References of "Leroy, Danielle"
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See detailEffects of marginal iron overload on iron homeostasis and immune function in alveolar macrophages isolated from pregnant and normal rats.
Ward, Roberta J; Wilmet, Stephanie; Legssyer, Rachida et al

in Biometals (2009), 22(2), 211-23

The effects of changes in macrophage iron status, induced by single or multiple iron injections, iron depletion or pregnancy, on both immune function and mRNA expression of genes involved in iron influx ... [more ▼]

The effects of changes in macrophage iron status, induced by single or multiple iron injections, iron depletion or pregnancy, on both immune function and mRNA expression of genes involved in iron influx and egress have been evaluated. Macrophages isolated from iron deficient rats, or pregnant rats at day 21 of gestation, either supplemented with a single dose of iron dextran, 10 mg, at the commencement of pregnancy, or not, showed significant increases of macrophage ferroportin mRNA expression, which was paralleled by significant decreases in hepatic Hamp mRNA expression. IRP activity in macrophages was not significantly altered by iron status or the inducement of pregnancy +/- a single iron supplement. Macrophage immune function was significantly altered by iron supplementation and pregnancy. Iron supplementation, alone or combined with pregnancy, increased the activities of both NADPH oxidase and nuclear factor kappa B (NFkappaB). In contrast, the imposition of pregnancy reduced the ability of these parameters to respond to an inflammatory stimuli. Increasing iron status, if only marginally, will reduce the ability of macrophages to mount a sustained response to inflammation as well as altering iron homeostatic mechanisms. [less ▲]

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See detailNew system for complexation of uranyl ions from liquid wastes of low-level activity: Polypyrrole doped with complexing polyanions
Leroy, Danielle ULg; Martinot, Lucien; De Becker, Michaël ULg et al

in Journal of Applied Polymer Science (2000), 77(6), 1230-1239

Polymer composites consisting of polypyrrole doped by uranyl complexing polyanions [i.e., poly(2-acrylamidoglycolic acid) and poly(2-acrylamido-2-methyl-1-propanesulfonic acid)] were electrochemically ... [more ▼]

Polymer composites consisting of polypyrrole doped by uranyl complexing polyanions [i.e., poly(2-acrylamidoglycolic acid) and poly(2-acrylamido-2-methyl-1-propanesulfonic acid)] were electrochemically synthesized. Bulk material and thin layers strongly adhering to inert supporting electrodes were prepared. These composites were used to precipitate uranyl ions from simulated radioactive wastes. Among different experimental techniques used for the analysis of uranium immobilized in the composites, the Rutherford backscattering of cu particles proved efficient in thin layers. Leaching tests confirmed the persistence of the uranium complexation in the solid composites. [less ▲]

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