Identification and quantification of concentration-dependent biomarkers in MCF-7/BOS cells exposed to 17β-estradiol by 2-D DIGE and label-free proteomicsCollodoro, Mike ; Lemaire, Pascale ; Eppe, Gauthier et alin Journal of Proteomics (2012), in press This paper reports the identification of biomarkers resulting from the exposure of MCF-7/BOS cells to 17β-estradiol (E2). The biomarkers were identified using 2 independent and complementary techniques, 2 ... [more ▼] This paper reports the identification of biomarkers resulting from the exposure of MCF-7/BOS cells to 17β-estradiol (E2). The biomarkers were identified using 2 independent and complementary techniques, 2-D DIGE / MALDI-TOF peptide mass fingerprint, and 2-D UPLC-ESI MS/MS. These markers form a preliminary molecular signature that can be used when testing the estrogenic activity of xenobiotics, either pure or in mixtures. [less ▲] Detailed reference viewed: 23 (12 ULg)![]() Hydrogen/Deuterium Exchange combined to MALDI Mass Spectrometry : The Importance of the Choice of the MatrixLemaire, Pascale ; Debois, Delphine ; Quinton, Loïc et alPoster (2010, May 25) Detailed reference viewed: 89 (18 ULg) Identification of biomarkers to estrogen exposure using MCF-7/BOS cell line exposed to 17β-estradiol and phytoestrogensCollodoro, Mike ; Bertrand, Virginie ; Lemaire, Pascale et alPoster (2009, June) Use of an estrogen responsive cell line and proteomic for biomarker discovery and the screening of xenoestrogen Detailed reference viewed: 35 (4 ULg) Imaging mass spectrometry reveals peptide distributions in MALDI samplesDebois, Delphine ; Lemaire, Pascale ; Quinton, Loïc et alPoster (2009, March) Detailed reference viewed: 14 (3 ULg) Global strategy for the development of estrogenic compounds detection screening testCollodoro, Mike ; ; Lemaire, Pascale et alPoster (2007, May) Detailed reference viewed: 9 (0 ULg) |
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