References of "Leemans, J"
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See detailCorrelation of bronchoalveolar eosinophilic percentage with airway responsiveness in cats with chronic bronchial disease
Allerton; Leemans, J; Tual, Charlotte ULg et al

in Journal of Small Animal Practice (2013), 54(5), 258-264

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See detailViral RNA load in semen from bluetongue serotype 8-infected rams: Relationship with sperm quality
Leemans, J.; Raes, M.; Vanbinst, T. et al

in Veterinary Journal (2012), 192(3), 304-310

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See detailSalmeterol or doxycycline do not inhibit acute bronchospasm and airway inflammation in cats with experimentally-induced asthma
Leemans, J.; Kirschvink, N.; Bernaerts, Frederique ULg et al

in Veterinary Journal (2011)

The objective of this study was to determine if inhaled salmeterol, a long-acting β2-adrenergic agonist, and oral doxycycline, a tetracycline antibiotic displaying matrix metalloproteinase (MMP ... [more ▼]

The objective of this study was to determine if inhaled salmeterol, a long-acting β2-adrenergic agonist, and oral doxycycline, a tetracycline antibiotic displaying matrix metalloproteinase (MMP) inhibitory activity, reduce airway inflammation and obstruction in cats with experimentally-induced asthma. Eight Ascaris suum (AS)-sensitised cats were enrolled in a prospective study in which they underwent four AS-challenges at 1 month intervals. The challenged animals were given no treatment or were treated on 4 consecutive days with either: (1) oral prednisolone (1 mg/kg twice daily), (2) inhaled salmeterol (50 μg twice daily), or (3) oral doxycycline (5 mg/kg twice daily), according to a randomised cross-over design. Inhibition of allergen-induced early (EAR) and late (LAR) asthmatic reactions were assessed by barometric whole-body plethysmography. Cytology and measurement of MMP-2 and -9 activities were carried out on bronchoalveolar lavage fluid (BALF). Although none of the treatments prevented the EAR, prednisolone treatment inhibited the LAR. Relative to untreated cats, the eosinophil percentage and MMP-2 activity in BALF were significantly reduced following prednisolone treatment (P < 0.05). Short-term therapy with either salmeterol or doxycycline had no effect on the EAR or LAR or on airway inflammation. Given the chronic nature of this disease in cats, long-term therapy may be required to produce more favourable functional and clinical outcomes. [less ▲]

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See detailImpact of age and breed on incidence of clinical signs after natural infection with bluetongue virus serotype 8 in sheep
Kirschvink, N.; Leemans, J.; Bolkerts, B. et al

Conference (2010, June)

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See detailActivity of metalloproteinases MMP2 and MMP9 in matched serum and bronchoalveolar lavage fluid samples in a dog model of airway inflammation
Manens, Jefferson ULg; Bolognin, M.; Leemans, J. et al

in 19h ECVIM Meeting - Porto, Portugal - 8-10 septembre 2009 (2009, September 08)

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See detailBarometric whole-body plethysmographic measurements in dogs suffering from brachycephalic airway obstruction syndrome.
Bernaerts, Frederique ULg; Talavera, J.; Leemans, J. et al

in Veterinary Journal (2008)

The clinical features of brachycephalic airway obstructive disease in 11 brachycephalic dogs are described in this study. The respiratory strategy was assessed before (n = 11) and after (n = 6) surgery ... [more ▼]

The clinical features of brachycephalic airway obstructive disease in 11 brachycephalic dogs are described in this study. The respiratory strategy was assessed before (n = 11) and after (n = 6) surgery using barometric whole-body plethysmography (BWBP), with the relationship between BWBP variables and the severity of the clinical signs assessed by the use of a respiratory score based on clinical, radiographic and endoscopic findings. Partial collapse of the left main bronchus was a common finding not previously described as part of the brachycephalic airway obstructive disease syndrome. Epiglottic cysts, laryngeal granulomas and nasopharyngeal turbinates in English Bulldogs were other previously unreported findings. No significant correlation between the respiratory score and any of the BWBP variables was detected. Compared to healthy dogs, brachycephalic dogs had a significantly lower Te/Ti ratio (expiratory time over inspiratory time), peak inspiratory flow (PIF) per kg bodyweight (BW), significantly higher peak expiratory flow (PEF) per kg BW, PEF/PIF, and enhanced pause. These variations are compatible with upper airway obstructions primarily in the extrathoracic airways. Following surgery, a significant decrease in PEF/PIF was detected. The study showed that BWBP could be used to characterise the respiratory strategy in brachycephalic dogs before and after surgery. [less ▲]

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See detailInvestigation of airway reactivity by barometric whole body plethysmography in cats with spontaneous bronchial disease
Bernaerts, Frederique ULg; Merveille, Anne-Christine ULg; Bolognin, M. et al

in 24th Symposium of the Veterinary Comarative Respiratory Society - Jena, Allemagne 8-10 octobre 2006 (2006, October)

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See detailInvestigation of the effect of salbutamol and prenisolone on lung function test in healthy dogs with experimentally induced airway inflammation
Bolognin, M.; Talavera, J.; Bernaerts, Frederique ULg et al

in 16th ECVIM Meeting - Amsterdam - Nederlands - Septembre 2006 (2006, September)

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See detailEffect of water intake on dietary mannitol, sodium chloride and food frequency in healthy cats
Kirschvink, N.; Lhoest, E.; Leemans, J. et al

in Proceedings of the 10th Congress ESVCN (2006)

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See detailEffects of feeding frequency on water intake in cats
Kirschvink, N.; Lhoest, E.; Leemans, J. et al

in Journal of Veterinary Internal Medicine (2005, May)

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See detailWater intake is influenced by feeding frequency and energy allowance in cats
Kirschvink, N.; Lhoest, E.; Leemans, J. et al

in Proceedings of the 9th Congress ESVCN (2005)

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See detailEffect of inhaled fluticasone on airway reactivity and 8-Iso-PGF2 in bronchoalveolar lavage fluid of cats
Kirschvink, N.; Leemans, J.; Delvaux, François ULg et al

in 5th China - France Pharmacological Joint Symposium - Beijing - France - Octobre 2004 (2004, October)

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See detailEffect of inhaled fluticasone on airway reactivity and inflammation in cats.
Kirschvink, N.; Leemans, J.; Delvaux, F. et al

in 22nd Veterinary and Comparative Respiratory Society Symposium - Montreal- Canada - Octobre 2004 (2004, October)

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See detailBronchial reactivity assessed by whole body barometric plethymography is correlated with lower airway inflammation in cats
Kirschvink, N.; Leemans, J.; Delvaux, François ULg et al

in 14th ESVIM Meeting - Barcelona - Espagne (2004, September)

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See detailPreventive use of bronchodilators reduces bronchoscopy-induced airflow limitation in cats
Kirschvink, N.; Leemans, J.; Delvaux, F. et al

in ACVIM Meeting - Minneapolis - USA - Juin 2004 (2004, June)

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See detailRadiographic signs induced by bronchoalveolar lavage in cats
Bernaerts, Frederique ULg; Kirschvink, N.; Leemans, J. et al

in 14th ESVIM Meeting - Barcelona - Espagne - Septembre 2004 (2004)

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See detailEffects of somatic growth, sex and circadian rhythm on respiratory parameters assessed by whole body barometric plethysmography in healthy cats
Leemans, J.; Kirschvink, N.; Delvaux, François ULg et al

in 14th ESVIM Meeting - Barcelona - Espagne (2004)

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See detailUse of a short-acting bronchodilator prevents bronchoscopy-induced airflow limitation in cats
Kirschvink, N.; Leemans, J.; Delvaux, François ULg et al

in 8th Annual Meeting de la Société Française de Pharmacologie - Strasbourg - France - Avril 2004 (2004)

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See detailMMP-2 and MMP-9 activity is increased in bronchoalveolar lavage fluid of asthmatic cats
Kirschvink, N.; Delvaux, François ULg; Leemans, J. et al

in Autumn Meeting, Belgian Society of Fundamental and Clinical physiology and Pharmacology - Liège - Belgique - novembre 2003 (2003, November)