References of "Lecloux, Geoffrey"
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See detailDRAMATIC OSTEONECROSIS OF THE JAW ASSOCIATED WITH ORAL BIPHOSPHONATES TREATMENT AFTER IMPLANT REMOVAL: A CASE REPORT
FERNANDEZ AYORA, Alberto ULg; HERION, Francine ULg; LAMBERT, France ULg et al

Poster (2013, October)

BACKGROUND Osteoporosis affects millions of elderly patients. Bisphosphonates represent first-line therapy. Osteonecrosis of the jaws in patients treated with bisphosphonates is mostly associated with ... [more ▼]

BACKGROUND Osteoporosis affects millions of elderly patients. Bisphosphonates represent first-line therapy. Osteonecrosis of the jaws in patients treated with bisphosphonates is mostly associated with intravenous bisphosphonates while the incidence associated with oral bisphosphonates is not significant. AIM This report documents a case of bisphosphonate-related osteonecrosis of the jaw (BRONJ) after dental implant removal in an osteoporotic patient treated with alendronate and risedronate for 15 years. MATERIAL AND METHODS An 83-years-old patient with no significant systemic disease underwent implant removal in the first molar left hemimandible position in 2010 due to a peri-implantitis. The surgical procedure was uneventful thought preventive measures were no taken. In June 2011, the patient was referred to our department with a wide bone sequestration of the left mandibular body. A panoramic radiograph showed an increased bone marrow density with bone sequestration. Since then, the patient underwent several courses of antibiotics and conservative therapy, without relief of symptoms. RESULTS Since 2011, the patient has lost 13 teeth in the mandible and the osteonecrosis has disseminated to the entire jaw and the left mandible condyle. The patient has even lost the left hearing. Resective surgery under general anesthesia is not indicated due to the risk because of the age of the patient. CONCLUSION AND CLINICAL IMPLICATIONS Despite the low risk of BRONJ occurrence after implant surgery in oral N-BP users, the fate of dental implants in these patients remains uncertain. Therefore patients at risk must be given a full explanation of the potential risks of implant failure and BRONJ development. Osteonecrosis of the jaws in association with bisphosphonate therapy is a very serious condition with which all dentists should be familiar. Since the treatment of BRONJ is difficult, prevention is the main goal. When the osteonecrosis begins, it can be very painful to the patient, difficult to treat, and can lead to very deleterious sequelae. [less ▲]

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See detailUn approche moderne de la régénération osseuse
LAMBERT, France ULg; LECLOUX, Geoffrey ULg; ROMPEN, Eric ULg

Scientific conference (2013, March)

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See detailA methodological approach to assessing alveolar ridge preservation procedures in humans: soft tissue profile.
VANHOUTTE, Vanessa ULg; ROMPEN, Eric ULg; LECLOUX, Geoffrey ULg et al

in Clinical Oral Implants Research (2013)

Introduction: The aesthetic results of implant restoration in the anterior maxilla are particularly related to the soft tissue profile. Although socket preservation techniques appear to reduce bone ... [more ▼]

Introduction: The aesthetic results of implant restoration in the anterior maxilla are particularly related to the soft tissue profile. Although socket preservation techniques appear to reduce bone remodelling after tooth extraction, there is still few investigations assessing the external soft tissue profile after such procedures. The goal of the present study was to describe an accurate technique to evaluate soft tissue contour changes after performing socket preservation procedures. The secondary objective was to apply the newly develop measuring method to a specific socket preservation using a “saddled” connective tissue graft combined with the insertion of slowly resorbable biomaterials into the socket. Materials and Methods: A total of 14 patients needing tooth replacement in the aesthetic region were included to receive a socket preservation procedure using a connective tissue graft. Impressions were taken before the tooth extraction (baseline) and at 2, 4, and 12 weeks after the procedure. The corresponding plaster casts were scanned, and the evolution of the soft tissue profile in relation to the baseline situation was assessed using imaging software. Results: The measuring technique allowed assessing the soft tissue profiles accurately at different level of the alveolar process. The insertion of a saddled connective tissue appeared to compensate significantly for the horizontal and vertical bone remodelling after a socket preservation procedure in most regions of the alveolar crest. After 12 weeks, the only significant change was located in the more cervical and central region of the alveolar process and reached a mean of 0.76 mm. Conclusion: Within the limitations of this study, we found that a saddled connective tissue graft combined with a socket preservation procedure could almost completely counteract the bone remodelling in terms of the external soft tissue profile. The minor changes found in the cervical region might disappear with the emergence profile of the prosthodontic components. The described technique might therefore enhance the aesthetic outcomes when a tooth has to be replaced in the aesthetic zone. The described protocol can be used to further compare the effectiveness of different extraction socket preservation protocols in randomised controlled trials. [less ▲]

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See detailBone Regeneration Using Porous Titanium Particles versus Bovine Hydroxyapatite: A Sinus Lift Study in Rabbits.
LAMBERT, France ULg; LECLOUX, Geoffrey ULg; Léonard, Angélique ULg et al

in Clinical Implant Dentistry & Related Research (2013), 15(3),

Aim: The first objective of this study was to qualitatively and quantitatively assess the bone formation process, particularly the long-term behavior and three-dimensional volume stability of subsinusal ... [more ▼]

Aim: The first objective of this study was to qualitatively and quantitatively assess the bone formation process, particularly the long-term behavior and three-dimensional volume stability of subsinusal bone regeneration, using titanium (Ti) or bovine hydroxyapatite (BHA) granules, in a rabbit model. The second objective was to evaluate the effect of the hydration of the BHA particles with a therapeutic concentration of doxycycline solution on the osteogenesis and biomaterial resorption. Materials and Methods: Rabbits underwent a double sinus lift procedure using one of three materials: grade 1 porous Ti particles, BHA, or BHA hydrated with doxycycline solution (0.1 mg/ml) (BHATTC). Animals were sacrificed after 1 week, 5 weeks, or 6 months. Samples were analyzed using µCT and nondecalcified histology. Results: The materials used in each of the three groups allowed an optimal bone formation; bone quantities and densities were not statistically different between the three groups. At 6 months, more stable three-dimensional volume stability was found with Ti and BHATTC (p = .0033). At 5 weeks and 6 months, bone to material contact corroborating osteoconduction was significantly higher with BHA and BHATTC than with Ti (p < .0001). Conclusions and Clinical Implications: Even though the studied biomaterials displayed different architectures, they are relevant candidates for sinus lift bone augmentation prior to dental implants because they allow adequate three-dimensional stability and osteogenesis. However, to recommend the clinical use of Ti, both an observation on the drilling effects of Ti particles and clinical trials are needed. [less ▲]

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See detailA comparison of three calcium phosphate based space fillers in sinus elevation: a study in rabbits
LAMBERT, France ULg; Léonard, Angélique ULg; LECLOUX, Geoffrey ULg et al

in The international Journal of Oral and Maxillofacial Implants (2013), 28(2), 393-402

Aim: Sub-sinusal bone regeneration procedures are reliable procedures that are known to be efficient with the use of biomaterials alone. Nevertheless, many types of biomaterials are available, and their ... [more ▼]

Aim: Sub-sinusal bone regeneration procedures are reliable procedures that are known to be efficient with the use of biomaterials alone. Nevertheless, many types of biomaterials are available, and their efficacy in terms of bone formation and resorption rate have rarely been compared. This study aimed to compare the bone formation, resorption rate, osteoconductivity and 3D volume changes of three biomaterials often used for alveolar ridge augmentation. Materials and Methods: Rabbits underwent a double sinus lift procedure using three different types of space fillers: bovine hydroxyapatite (BHA), beta calcium phosphate (ß-TCP) and biphasic calcium phosphate (BCP). Animals were sacrificed at 1 week, 5 weeks and 6 months. Samples were subjected to X-ray microtomography and histology. Qualitative analysis was performed on non-decalcified sections, and quantitative histomorphometric analysis was conducted using SEM. Volume variations of bone augmentations were calculated at different time points. Results: All three particulated biomaterials proved to be effective in promoting osteogenesis. At 6 months, biomaterial resorption rates were significantly different across the 3 groups (p<0.0001). The highest resorption rate was found with β-TCP, in which only 6.7% of the baseline particle surface remained. At 6 months, bone was in close contact with the BHA particles, constituting a composite network; in contrast, BCP particles were often surrounded by soft tissues. In each group, no significant difference in volume variations were found at the different time point. Conclusions and clinical implications: Despite the limitations of the study, the three particulated space-filling biomaterials proved to be efficient to promote osteogenesis. High resorption rates and complete replacement of the biomaterials by bone seemed to withstand intrasinusal pressure. Further investigations in humans should consider longer follow-up periods. [less ▲]

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See detailPiezocision-assisted orthodontic treatment in adult patient: A case report
CHARAVET, Carole ULg; LAMBERT, France ULg; LECLOUX, Geoffrey ULg et al

Conference (2012, December 07)

The duration of orthodontic treatments in adult patient remains a barrier for some patients. The recent scientific reports describing piezocision technique involving minimally invasive corticotomies, seem ... [more ▼]

The duration of orthodontic treatments in adult patient remains a barrier for some patients. The recent scientific reports describing piezocision technique involving minimally invasive corticotomies, seem to be of interest for these particular cases. The present communication describes the clinical case of a 20-year-old patient presenting a class I bilateral, an overcrowding of front areas with the superior canine in mesio-infraclusion and a deviated lower median line. An excellent multidisciplinary approach is mandatory for the planification of such cases. Under local anesthesia, the surgical technique involves vertical minimal incision around the teeth that need to be moved. Trough the minimal incisions, 5mm vertical alveolar osteotomies are performed using ultrasonic surgical device. No suture is necessary. The orthodontic activation is applied 1 week before the surgical procedure and the patient is recalled every 15 days to activate the orthodontic appliance. In this case self-ligating brackets were used to reduce the friction. Post-operative outcomes were painless for the patient and the complete orthodontic procedure took 7 months. The overall treatment appeared to be faster than a conventional orthodontic treatment. However, even if animal studies seem to confirm the clinical feeling described in this case report, further clinical studies including randomized controlled trials are needed to validate this treatment approach. [less ▲]

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See detailTraitement orthodontique chez le patient adulte assisté par piezocision : Illustration d'un cas clinique
CHARAVET, Carole ULg; LECLOUX, Geoffrey ULg; LAMBERT, France ULg et al

Poster (2012, November)

La durée des traitements orthodontiques chez l’adulte reste une barrière pour certains d’entre eux. La littérature scientifique récente qui décrit la technique de piezocision impliquant des corticotomies ... [more ▼]

La durée des traitements orthodontiques chez l’adulte reste une barrière pour certains d’entre eux. La littérature scientifique récente qui décrit la technique de piezocision impliquant des corticotomies à minima semble être intéressante pour traiter ce type de patient. Cette communication décrit le cas clinique d’une patiente de 20 ans présentant une classe I bilatérale, un encombrement des fronts avec les canines supérieures en vestibulomésioinfraclusion et une ligne médiane inférieure déviée à droite. Une planification multidisciplinaire est indispensable pour traiter ce genre de cas. La technique chirurgicale nécessite une anesthésie locale. Des incisions verticales à minima sont réalisées en vestibulaire, de part et d’autre des dents à déplacer. Ensuite, par cette petite incision, une corticotomie inter-radiculaire de 5mm de long est réalisée à l’aide d’un piezotome. Il n’est pas nécessaire de suturer. Un appareil fixe multiattache est posé 1 semaine avant la procédure chirurgicale et le patient est convoqué tous les 15 jours activé. Dans ce cas, un appareil fixe bimaxillaire auto-ligaturant a été placé pour une friction minimale. Les suites post-opératoires pour le patient ont été minimes et la durée totale du traitement orthodontique a été de 7 mois. Le traitement dans sa globalité semble donc avoir été plus rapide qu’un traitement classique. Cependant, même si des études animales semblent confirmer le sentiment clinique décrit dans ce cas, des études cliniques contrôlées randomisées sont nécessaires pour valider cette approche de traitement. [less ▲]

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See detailA methodological approach to assessing alveolar ridge preservation procedures in humans: hard tissue profile.
LAMBERT, France ULg; Vincent, Kim; VANHOUTTE, Vanessa ULg et al

in Journal of Clinical Periodontology (2012), 9

AIMS: Multiple surgical protocols using biomaterials have been proposed to limit the typical post-extraction bone resorption. However, because of the heterogeneity of the studies, particularly the ... [more ▼]

AIMS: Multiple surgical protocols using biomaterials have been proposed to limit the typical post-extraction bone resorption. However, because of the heterogeneity of the studies, particularly the differences in assessment methods, it is difficult to determine the superiority of one technique over another. The objective of this study was to describe a new radiographic method to draw a map of alveolar bone remodelling after alveolar ridge preservation procedures to compare different surgical techniques more accurately. The newly developed measuring method was applied to a case series describing a specific preservation technique. MATERIALS AND METHODS: Fourteen extraction sites (in 14 patients) located in the upper anterior maxilla were treated with bovine hydroxyapatite (0.25- to 1-mm particles) and a saddled connective tissue graft. A radiographic three-dimensional assessment of the hard tissues was performed at baseline and 3 months after the procedure. Standardized horizontal measurements were taken at three corono-apical levels (-2, -5 and -9 mm) and at three mesio-distal levels (mesial, centre and distal) in the buccal and palatal aspects. Vertical measurements were also recorded in nine regions superior to the alveolar crest. The measurements were performed by two independent observers and intra- and inter-observer effects were evaluated. RESULTS: No inter- and intra-observer effects were found when analysing the measurements from these two observers. The horizontal dimension of the crest decreased by 1.6 mm (20%) in the cervical regions (-2 mm level), decreased moderately, by 1 mm (12%), at the -5 mm level and decreased very little, 0.5 mm (6%), at the apical (-8 mm) level. The losses were always significantly higher in the buccal than in the palatal aspect. Buccally, the maximal bone remodelling at the cervical level remained below 1 mm. Vertical bone resorption was homogeneous and<1 mm in the nine measured regions. DISCUSSION: The radiographic measuring methodology proved to be reproducible. It can be applied in other clinical settings. It successfully assessed the alveolar ridge preservation technique (BHA+saddle connective tissue graft). [less ▲]

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See detailEarly Implant placement in socket preservations: 12-month results of a prospective case series.
DETHIER, Frédéric ULg; LECLOUX, Geoffrey ULg; ROMPEN, Eric ULg et al

Poster (2012, June)

Objectives: The aim of this study was to evaluate the clinical and histological outcomes of implant placed after socket preservation procedures in the esthetic zone. Implant survival rate and biological ... [more ▼]

Objectives: The aim of this study was to evaluate the clinical and histological outcomes of implant placed after socket preservation procedures in the esthetic zone. Implant survival rate and biological complications were recorded during a follow-up period of 1 year. Materials and methods: A series of 12 patients needing the replacement of a single tooth in the esthetic zone were included in the present study. The hopeless teeth were extracted atraumatically, the sockets were filled with bovine hydroxyapatite (0.25-1mm particles) and the sites were covered with a saddled connective tissue graft. After a healing period of 3 months, biopsies were retrieved in the socket preservation sites and implants were placed. The patients were followed for a period of 1 year. Results: The etiologies of tooth loss were : endodontic (9), caries (1), periodontal (1), and traumatic (1). A total of 12 implants (10 incisors, 2 premolars) were placed on 12 patients (6 men / 6 women) aged from 24 to 61 (42,3 – 11,91). All implant reached an adequate primary stability (> 20N/cm2). 7 out of 12 implants were immediately restored with a temporary crown, and the définitive restorations were successfully placed in all cases. After a follow-up period of 1 year, all implants fulfilled strict success criteria for dental implants with regard to osteointegration, including the absence of peri-implant radiolucency, implant mobility, suppuration, and pain and no further complications occurred. Out of 12 sites only 7 biopsies were retrieved for histological analyses. New bone was found in the apical third of the socket in every specimen, in the mid-third in only 3 specimen and no bone was found in any of the spécimen in the more cervical third of the socket. Conclusion: The results from this prospective case series suggest that early implant placement in extraction socket site seems to display good clinical outcomes despite the incomplete bone regeneration in the socket at 3 months. [less ▲]

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See detailDescription of a ‘soft tissue friendly’ protocol for immediate loading in the esthetic zone: 1 year result of 13 consecutive patients
COMPEYRON, Yoann ULg; LECLOUX, Geoffrey ULg; ROMPEN, Eric ULg et al

Poster (2012, June)

Objectives: Repeted abutment connection and disconnections compromize the connective and epithelial sealing around implant components, leading to peri-implant bone remodeling (Abrahamsson, 1997). Placing ... [more ▼]

Objectives: Repeted abutment connection and disconnections compromize the connective and epithelial sealing around implant components, leading to peri-implant bone remodeling (Abrahamsson, 1997). Placing the definitive abutment at the time of implant placement might be a treatment option to minimize this biological rupture. The aim of this study was to evaluate the effectiveness of pre-shaped zirconium abutments for immediate implant loading in the anterior maxilla. Materials and methods: A total of 13 patients needing the placement of one or several implant in the esthetic zone were treated with Regular Crossfit Bone Level (Straumann) implants. Implants were placed and immediately restored with a pre-shaped zirconium abutments and provisional resin crowns if the primary stability reached at least 20 N/cm2. Implant survival rate, biological and prosthodontic complications as well as peri-implant tissue status (papilla index) were recorded during a follow-up period of 1 year. Results: A total of 14 implants (8 incisors, 1 canines, 5 premolars) placed in 11 patients (4 men / 7 women) aged from 22 to 60 years old (48,5 +/- 11,5) could be assessed for the entire follow-up period. 2 patients dropped out. All implants reached an adequate primary stability (> 20N/cm2) to perform an immediate implant restoration. Straight pre-shaped Zirconium abutment was used in each case. Six implants were placed in socket preservation sites and five implants were placed simultaneously with a GBR. After a follow-up period of 1 year, all implants fulfilled survival criteria for dental implants with regard to osteointegration, including the absence of peri-implant radiolucency, implant mobility, suppuration, and pain. One abutment screw loosening was observed during the provisional period and no abutment fracture occurred. Definitive full ceramic-cemented restorations were successfully performed on each implant after a mean period of 6 months and no further complications occurred. In 11 out of 14 implants, an improvement of the papilla index was observed from baseline to 1 year follow-up whereas 3 implants showed a decrease of this index. Conclusion: The results from this prospective case series suggest that immediately restored implants using a final pre-shaped zirconium abutment in esthetic zone display favorable implant and prosthodontic outcomes and seems to allow an adequate papilla index improvement in most of the cases. [less ▲]

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See detailPatient morbidity after socket preservation using a connective tissue graft versus a bilayer collagen matrix: Preliminary results of a comparative Randomized Control Trial.
FERNANDEZ AYORA, Alberto ULg; VANHOUTTE, Vanessa ULg; LECLOUX, Geoffrey ULg et al

Poster (2012, June)

INTRODUCTION AND AIM: The present randomized controlled trial compared socket preservation procedures using bovine hydroxyapatite (Bio-Oss®, Geistlich, Switzerland) covered with a connective tissue graft ... [more ▼]

INTRODUCTION AND AIM: The present randomized controlled trial compared socket preservation procedures using bovine hydroxyapatite (Bio-Oss®, Geistlich, Switzerland) covered with a connective tissue graft (CT) versus a bilayer collagen membrane (CM) (Mucograft®, Geistlich, Switzerland), placed from buccal to palatal in split-thickness pouches in order to seal the extraction site and to potentially thicken the buccal mucosa. The aim of this present abstract was to evaluate post-operative complications and patient-centered outcomes of the two independent surgical protocols. METHODS: This randomized controlled trial included 26 patients (16 female, 10 male) aged from 20 to 69 years (mean: 42.6, SD: 12). 26 teeth were extracted atraumatically and the 2 distinct surgical protocols were applied randomly. Patients filled out a VAS form 1 week after the surgery to evaluate their level of discomfort and post-operative pain. Drug intakes as well as complications were also recorded. RESULTS: No statistical significant differences were found between the 2 groups in terms of post-operative complications (bleeding) and post-operative pain. The consumption of painkillers after the surgery decreased over time but was similar in the two groups. CONCLUSION: According to the preliminary results of the present RCT, none of both protocols seemed to induce significant post-operative pain and discomfort. There was no difference between the two procedures regarding post-operative complications and patient centered outcomes. [less ▲]

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See detailPatient morbidity after 2 different surgical protocols to treat miller class I recession in the anterior maxilla: A Comparaitive Ramdomized Control Trial.
SALHI, Leila ULg; ROMPEN, Eric ULg; LECLOUX, Geoffrey ULg et al

Conference (2012, June)

Aim: The objective of this study was to compare two different periodontal plastic surgery procedures to treat Miller’s class I recession: a coronally advanced flap (control group) versus the pouch ... [more ▼]

Aim: The objective of this study was to compare two different periodontal plastic surgery procedures to treat Miller’s class I recession: a coronally advanced flap (control group) versus the pouch technique (test group), both of which were associated with connective tissue graft. Methods: Forty consecutive patients were included, with 20 patients being allocated for each group. The level of recession coverage, the keratinised tissue quantity, gingival aesthetics (PES), and postoperative outcomes were assessed for a follow-up period of 6 months. Results: After 6 months, both techniques allowed for the excellent mean root coverage of 96.3 ± 12.1% in the control group and of 91.3 ± 17.6% in the test group. Complete root coverage was achieved in 89.5% (17/19) and 79% (15/19) of the recession cases in the control and the test groups, respectively. A significant increase in keratinised tissue height (p=0.0011) was observed in the test group. A significant improvement in the pink aesthetic score was found in the 2 groups, but gingival texture displayed significantly better results in the test group (p<0.0001). No significant difference between the 2 groups was found in terms of the morbidity outcomes. Pain killer consumption was similar in the 2 groups and significantly decreased over time. [less ▲]

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See detailTechnologies in Periodontology: Avantages of the Piezosurgey
LAMBERT, France ULg; LECLOUX, Geoffrey ULg

Conference (2011, February 18)

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See detailDescription of the bone-remodeling pattern after socket preservation procedures in human: a methodological study
LAMBERT, France ULg; VINCENT, Kim ULg; VANHOUTTE, Vanessa ULg et al

Poster (2011)

Background: The bone remodeling after tooth extraction can result in the loss of as much as 50% of the buccal wall and a global crestal reduction in width of 3.87mm according to a recent systematic review ... [more ▼]

Background: The bone remodeling after tooth extraction can result in the loss of as much as 50% of the buccal wall and a global crestal reduction in width of 3.87mm according to a recent systematic review. Multiple surgical protocols using biomaterials are proposed in order to limit the typical postextraction bone resorption. However, because of the heterogeneity of the studies and, more specifically, of the assessment methods, it is difficult to assert the superiority of one technique over another. Aim: The objective of this study was to develop a new radiographic method to assess alveolar bone remodeling after socket preservation procedures. Methods: Sixteen extraction sites (in 14 patients) localized in the upper anterior maxilla were treated with bovine hydroxyapatite (0.25–1mm particles) and a saddled connective tissue graft. A radiographic 3-dimensional assessment of the hard tissues was performed at baseline and at 3 months after the procedure. Standardized horizontal measurements were taken at three corono apical levels ( 2, 5, and 9mm) and at three mesio-diatal level (Mesial, Center, and Distal) in the buccal and palatal aspects. Vertical measurements were also recorded in nine regions over the top of the alveolar crest. Results: Extraction socket-preservation technique assessed in the present study significantly reduced horizontal bone remodeling. The horizontal dimension of the crest decreased by 1.6mm (20%) in the cervical regions ( 2mm level), experienced a moderate decrease of 1mm (12%) at the 5mm level, and experienced a very low decrease of 0.5mm(6%) in the apical ( 8mm) level. The losses were always significantly higher in the buccal than in the palatal aspect. Buccally, the maximal bone remodeling at the cervical level remained below 1mm. Vertical bone resorption was homogeneous and was < 1mm in the nine measured regions. Conclusions and clinical implications: The radiographic measuring methodology proved to be accurate and reproducible. It can be applied in other clinical settings. Moreover, the surgical procedure evaluated in the present study, significantly limits the postextraction buccal bone remodeling compared with the data found in the literature for untreated extraction socket in the aesthetic area. However, a complete inhibition of the bone remodeling was not reached and the authors suggest a surgical technique using a ‘‘saddled’’ connective tissue graft to thicken buccal soft tissue biotype and consequently compensate for cervical bone loss. [less ▲]

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See detailBone regeneration using porous titanium particles vs. bovine hydroxyapatite: a sinus lift study in rabbits
LAMBERT, France ULg; LECLOUX, Geoffrey ULg; Léonard, Angélique ULg et al

Poster (2011)

Background: The use of porous titanium particles as space filling biomaterials for intraoral bone regeneration might be of interest because of both the mechanical stability and nonresorbable properties ... [more ▼]

Background: The use of porous titanium particles as space filling biomaterials for intraoral bone regeneration might be of interest because of both the mechanical stability and nonresorbable properties. Titanium particles were recently described for bone regeneration in sinus lifts and in the treatment of periimplantitis. Nevertheless, tissue integration and 3D bone regeneration with titanium particles were poorly explored in these previous reports. Aim: The first objective of this study was to qualitatively and quantitatively assess the bone formation process, particularly the long-term behavior and 3D volume stability of subsinusal bone regeneration, using titanium or bovine hydroxyapatite granules, in a rabbit model. The second objective was to evaluate the effect of the hydration of the BHA particles with a therapeutic concentration of doxycycline solution on the osteogenesis and biomaterial resorption. Methods: Rabbits underwent a double sinus lift procedure using one of three materials: grade 1 porous titanium particles (Ti), bovine hydroxyapatite (BHA) or chemically modified bovine hydroxyapatite (BHATTC). Animals were sacrificed after 1 week, 5 weeks or 6 months. Samples were analyzed using mCT and nondecalcified histology. Results: The materials used in each of the three groups allowed an optimal bone formation; bone quantities and densities were not statistically different between the three groups. At 6 months, more stable 3D volume stability was found with TI and BHATTC (P¼0.0033). At 5 weeks and 6 months, bone to material contact (BMC) corroborating osteoconduction was significantly higher with BHA and BHATTC than with Ti (P < 0.0001). Conclusions and clinical implications: Even though the studied biomaterials displayed different architectures, they are relevant candidates for sinus lift bone augmentation before dental implants because they allow adequate 3D stability and osteogenesis. However, to recommend the clinical use of Ti, both an observation on the drilling effects of Ti particles and clinical trials are needed. [less ▲]

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See detailRevisited rules of papilla level adjacent to single-tooth dental implants according recent implant designs. A retrospective study.
LECLOUX, Geoffrey ULg; Beaujan, Laurie; ROMPEN, Eric ULg et al

Poster (2010, October)

Background: According to Choquet and Tarnow principles (2001), a papilla is always present if the distance from the base of the contact point between two crowns to the crest of the bone is 5 mm or less ... [more ▼]

Background: According to Choquet and Tarnow principles (2001), a papilla is always present if the distance from the base of the contact point between two crowns to the crest of the bone is 5 mm or less. The arrival of new designs in implantology suggested more tissue preservation and so a possible evolution for the aesthetic treatments. Aim: This study was designed to determine whether the distance from the base of the contact point to the crest of the bone would correlate with the presence or absence of the interproximal papillae adjacent to single-tooth implants using the recent implant designs. Methods: A clinical, photographical and radiographical retrospective evaluation of the papilla level around single dental implants and their adjacent teeth was performed in the anterior maxilla in 34 patients restored with 39 implants. These implants were loaded at least 6 months and present a modified profile (Implants : NobelConcept and NobelActive, Nobel Biocare ; Bone Level, Straumann. Abutments : Platform-switching and curvy). Sixty-three papillae were available for evaluation. The Jemt index, the vertical distance between the base of the contact point and the bone crest, the distance from the papilla level to the contact point were measured. The measurements were rounded off to the nearest 0,001 millimeter and used with calibration computer programs (ImageJ) to be analyzed. The statistical analyses were realized with SAS program (SAS Institute, Cary, NC, USA). Results: When the measurements from the contact point to the crest of bone was 5 mm or less, the papilla was present 100% of the time. When the distance was 6 mm, the papilla was present 96% of the time. And when the distance was 7 and 8 mm, the papilla was present 57,14% and 50% of the time. Conclusions and clinical implications: These results show the influence of the bone crest on the presence or absence of papillae between implants and adjacent teeth. The data also show a positive influence for recent designs of implant and abutment systems. This designs shift the actual critical bone distance under the contact point from 5mm to 6mm and could improve the aesthetic outcome. [less ▲]

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