La pyknocytose infantile : une anemie neonatale mal connue a propos de 5cas.
Limme, Boris ; Dresse, Marie-Françoise ; et al
in Archives de Pédiatrie (2008), 15(12), 1765-8
Infantile pyknocytosis (IP) is a rare hematological entity of newborns. It is a form of hemolytic anemia with unusual red cell morphology: the red blood cells are distorted, irregular, and small with many ... [more ▼]
Infantile pyknocytosis (IP) is a rare hematological entity of newborns. It is a form of hemolytic anemia with unusual red cell morphology: the red blood cells are distorted, irregular, and small with many projections. Spontaneous resolution usually occurs by 4-6months of age. OBSERVATION: We describe the clinical features and biological parameters of 5 cases of IP. The first symptoms were always early jaundice, which required phototherapy. Anemia was severe in all babies and red blood cell transfusion was needed. CONCLUSION: IP is a rare cause of neonatal anemia whose diagnosis is based on a careful peripheral blood smear examination. In our study, anemia was severe and required red blood cell transfusion. Ethnic specificity and familial occurrence are reported in our experience. [less ▲]Detailed reference viewed: 228 (12 ULg)
Inositide-specific phospholipase c beta1 gene deletion is a rare event in myelodysplastic syndromes.
Herens, Christian ; ; Tassin, Françoise et al
in Leukemia (2006), 20(3), 521-2522-3Detailed reference viewed: 16 (8 ULg)