References of "Hoyoux, Claire"
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See detailPurpura thrombocytopénique idiopathique...idiopathique, vraiment?
LONGTON, Julie ULg; DRESSE, Marie-Françoise ULg; Florkin, Benoît et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2016), 18(1), 112

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See detailConcomitant nodal involvement by Langerhans cell histiocytosis and Hodgkin's lymphoma
Geurten, Claire ULg; THIRY, Albert ULg; Jamblin, Paul et al

in Pediatrics International : Official Journal of the Japan Pediatric Society (2015), 56(6), 1214-1217

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See detailConcomitant nodal involvement by Langerhans Cell Histiocytosis and Hodgkin Lymphoma
Geurten, Claire ULg; THIRY, Albert ULg; Jamblin, Paul et al

Poster (2015, March 12)

Introduction : Langerhans cell histiocytosis is defined as a clonal neoplastic proliferation of myeloid dendritic cells that upon activation migrate from the mucosal to lymph nodes. Definitive diagnosis ... [more ▼]

Introduction : Langerhans cell histiocytosis is defined as a clonal neoplastic proliferation of myeloid dendritic cells that upon activation migrate from the mucosal to lymph nodes. Definitive diagnosis is made by anatomo-pathological and immunohistochemical analysis. Langerhans cell histiocytosis is rarely, yet not exceptionally, found coexisting with other malignant neoplasms, suggesting it might arise in reaction to the cytokinic secretion of malignant cells. Case : We report the case of a 10-year-old female presenting with an isolated laterocervical lymphadenopathy and a mild general condition alteration tracing back to two months earlier. Nodal biopsy was performed and revealed concomitant involvement by Langerhans cell histiocytosis and Hodgkin lymphoma. Treatment of lymphoma led to the disappearance of the whole symptomatology. Discussion : Literature beholds reports of 30 cases of the simultaneous occurence of Hodgkin lymphoma with Langerhans cell histiocytosis, which is more than fortuitous regarding the low incidence of both diseases. A common etiology could explain such an association, but it might also be possible that background inflammatory cells of Hodgkin lymphoma stimulate the proliferation of Langerhans cells, making it a reactive process when occurring simultaneously with other neoplasms. Clinicians should thus be aware of the possibility of this association and carefully exclude any other life-threatening malignant proliferation when confronted to apparently isolated Langerhans cell histiocytosis. [less ▲]

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See detailTumeurs rhabdoïdes néonatales : à propos de deux cas.
Carichon, T; FORGET, Patricia ULg; Piette, Caroline ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015), 17(1),

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See detailPosterior Reversible Encephalopathy Syndrome in Pediatric Leukemia
Carichon, Tifenn ULg; Piette, Caroline ULg; Florkin, Benoît et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015), 17(1), 48

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See detailSchizencephaly associated with a severe prothrombotic syndrome caused by antithombin III deficiency
Daron, Aurore; DRESSE, Marie-Françoise ULg; Hoyoux, Claire ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015), 17(1), 109

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See detailUNE TUMEUR RARE DE LA FACE CHEZ UN NOURRISSON DE 6 MOIS
Fontaine, C; DEMEZ, Pierre ULg; FORGET, Patricia ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015), 17(1), 46

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See detailLE CANCER DU TRES JEUNE ENFANT : EPIDEMIOLOGIE LIEGEOISE
Fontaine, C; RIGO, Vincent ULg; FORGET, Patricia ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015), 17(1), 47

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See detailOsteopetrosis mimicking juvenile myelomonocytic leukemia.
Hoyoux, Claire ULg; DRESSE, Marie-Françoise ULg; FORGET, Patricia ULg et al

in Pediatrics International : Official Journal of the Japan Pediatric Society (2014)

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See detailOsteopetrosis mimicking juvenile myelomonocytic leukemia.
Hoyoux, Claire ULg; DRESSE, Marie-Françoise ULg; Forget, Patricia et al

in Pediatrics international : official journal of the Japan Pediatric Society (2014), 56(5), 779-82

A 5-month-old boy developed splenomegaly, anemia, thrombocytopenia with elevated white cells, monocytosis and immature granulocytes in the peripheral blood. Bone marrow showed dysplasia without blastosis ... [more ▼]

A 5-month-old boy developed splenomegaly, anemia, thrombocytopenia with elevated white cells, monocytosis and immature granulocytes in the peripheral blood. Bone marrow showed dysplasia without blastosis. Increased colony-forming unit-granulocyte-macrophage was found in the peripheral blood, mimicking granulocyte-macrophage colony-stimulating factor hypersensitivity. These findings fulfilled the diagnosis criteria for juvenile myelomonocytic leukemia (JMML), but no mutations in the CBL, NRAS, KRAS, or PTPN11 genes were detected. In addition to these findings severe hypogammaglobulinemia and elevated alkaline phosphatase were present. Bone X-ray showed dense and radiopaque bones with a bone-in-bone appearance characteristic of infantile malignant osteopetrosis (IMO). Genetic mutation in T-cell, immune regulator 1 (TCIRG1) was identified, confirming the diagnosis of IMO. Careful differential diagnosis including osteopetrosis, is therefore recommended in patients with clinical features and hematologic findings consistent with JMML. [less ▲]

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See detailParavertebral Burkitt’s Lymphoma in a Child: An Unusual Presentation
Hoyoux, Claire ULg; FORGET, Patricia ULg; Piette, Caroline ULg et al

in Case Reports in Medicine (2012), Article ID 891714, 4 pages

Paravertebral malignant tumors constitute 4.8% of cancer cases in pediatric oncology and are mostly composed of neuroblastoma (46.4%) and soft tissue sarcomas (35.7%). We describe the case of a Caucasian ... [more ▼]

Paravertebral malignant tumors constitute 4.8% of cancer cases in pediatric oncology and are mostly composed of neuroblastoma (46.4%) and soft tissue sarcomas (35.7%). We describe the case of a Caucasian 6-year-old boy who was admitted for middle back pain radiated to limbs and progressively increasing weakness of the legs, suggesting a spinal cord disease. The exploration revealed two paravertebral masses extending through the neural foraminae into the epidural space. The association with elevated serum neuron specific enolase suggested at first the diagnosis of neuroblastoma, but the pathological examination revealed a Burkitt’s lymphoma. This is a rare location of sporadic Burkitt’s lymphoma with neurologic syndrome as first symptoms. [less ▲]

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See detailA Case of Osteosarcoma in a Patient With Pycnodysostosis
Cortisse, Natasha; FORGET, Patricia ULg; DRESSE, Marie-Françoise ULg et al

in American Journal of Pediatric Hematology/oncology (2012), 34

Pycnodysostosis is a rare sclerosing bone dystrophy. The main clinical features are short stature and oral and maxillofacial abnormalities such as a large head, a small and underdeveloped face with ... [more ▼]

Pycnodysostosis is a rare sclerosing bone dystrophy. The main clinical features are short stature and oral and maxillofacial abnormalities such as a large head, a small and underdeveloped face with prominent nose and eyes, irregular dentition, small hands and feet with dystrophic nails, and trunk deformities such as scoliosis. The differential diagnosis is established with other skeletal dysplasias such as osteopetrosis, cleidocranial dysplasia, and idiopathic acroosteolysis. Since its first description in 1962 by Maroteaux and Lamy, about 100 cases have been published, some of these with uncommon features. We describe the case of a 22-year-old European man with pycnodysostosis who developed a chondroblastic osteosarcoma of the right femur. No case of bone cancer in this sclerosing bone disease had been described so far. [less ▲]

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See detailManagement of Diffuse Gliomas in Children: a retrospective study of 27 cases and review of the literature
Piette, Caroline ULg; Deprez, Manuel; Born, Jacques et al

Conference (2008)

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See detailManagement of diffuse glioma in children: a retrospective study of 27 cases and review of literature.
Piette, Caroline ULg; Deprez, Manuel ULg; Born, Jacques et al

in Acta Neurologica Belgica (2008), 108(2), 35-43

Gliomas are the most common CNS tumours in children and present either as circumscribed tumours or diffusely infiltrative neoplasms. Diffuse gliomas develop both in the cerebral hemispheres and the ... [more ▼]

Gliomas are the most common CNS tumours in children and present either as circumscribed tumours or diffusely infiltrative neoplasms. Diffuse gliomas develop both in the cerebral hemispheres and the brainstem and have a poor prognosis. Guidelines for the therapy of these tumours are still debated. In this study, we reviewed the clinical features of 27 consecutive patients with diffuse gliomas admitted to the Department of Paediatrics of CHR Citadelle, University of Liege, between 1985 and 2005. We review their clinical presentation, diagnosis, treatment and outcome with reference to the published literature. [less ▲]

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See detailPediatric gastric lymphoma: a rare entity.
Jacquemart, Caroline; Guidi, Ornella; Etienne, Isabelle et al

in Journal of Pediatric Hematology/Oncology : Official Journal of the American Society of Pediatric Hematology/Oncology (2008), 30(12), 984-6

Primary gastric lymphoma is a rare event in childhood. We describe a 13-year-old boy with gastric Burkitt-like lymphoma localized in the fundus. Symptoms mimicking gastritis-epigastric pain, hypochromic ... [more ▼]

Primary gastric lymphoma is a rare event in childhood. We describe a 13-year-old boy with gastric Burkitt-like lymphoma localized in the fundus. Symptoms mimicking gastritis-epigastric pain, hypochromic anemia, anorexia, and weight loss had been present for a few months before diagnosis. No Helicobacter pylori infection was shown at diagnosis. Biopsies obtained by ultrasound gastroscopy proved the diagnosis; F-fluorodeoxyglucose-positron emission tomography detected an isolated large gastric hypermetabolic mass. According to the international FAB/LMB 96 trial, the patient was treated with chemotherapy alone and is in first complete remission 2(1/2) years after diagnosis. [less ▲]

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See detailSecondary cancers in childhood
FORGET, Patricia ULg; DRESSE, Marie-Françoise ULg; Schmitz, V et al

in Revue Médicale de Liège (2006), 61(2), 76-80

Improved survival of pediatric cancer patients will lead to an increase of late sequellae such as secondary malignant neoplasms (SMN). Specific pediatric factors predisposing to these SMN are as follows ... [more ▼]

Improved survival of pediatric cancer patients will lead to an increase of late sequellae such as secondary malignant neoplasms (SMN). Specific pediatric factors predisposing to these SMN are as follows: long expecting duration of life, high cellular proliferative potential, toxicity of often combined cancer therapies (radio- and chemotherapies) and more frequent genetic predisposition to cancer. Better understanding of these factors could improve patients management and could lead to the development of less toxic future therapies with the hope to decrease the risk of SMN. [less ▲]

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See detailF-18-FDG PET in children with lymphomas
Depas, Gisèle ULg; De Barsy, Caroline; Jerusalem, Guy ULg et al

in European Journal of Nuclear Medicine and Molecular Imaging (2005), 32(1), 31-38

Purpose: The aim of this study was to retrospectively evaluate the performance of positron emission tomography (PET) with F-18-fluorodeoxyglucose (F-18-FDG) in children with lymphomas, at various stages ... [more ▼]

Purpose: The aim of this study was to retrospectively evaluate the performance of positron emission tomography (PET) with F-18-fluorodeoxyglucose (F-18-FDG) in children with lymphomas, at various stages of their disease. Methods: Twenty-eight children (mean age 12.5 years, 14 girls, 14 boys) with Hodgkin's disease (HD, n=17) or non-Hodgkin's lymphoma (NHL, n= 11) were evaluated. Patients were investigated at initial staging (n=19), early in the course of treatment (n=19), at the end of treatment (n=16) and during long-term follow-up (n=19). A total of 113 whole-body PET studies were performed on dedicated scanners. PET results were compared with the results of conventional methods (CMs) such as physical examination, laboratory studies, chest X-rays, computed tomography, magnetic resonance imaging, ultrasonography and bone scan when available. Results: At initial evaluation (group 1), PET changed the disease stage and treatment in 10.5% of the cases. In early evaluation of the response to treatment (group 2), PET failed to predict two relapses and one incomplete response to treatment. In this group, however, PET did not show any false positive results. There were only 4/75 false positive results for PET among patients studied at the end of treatment (group 3, specificity 94%) or during the systematic follow-up (group 4, specificity 95%), as compared with 27/75 for CMs (specificity 54% and 66%, respectively). Conclusion: F-18-FDG-PET is a useful tool for evaluating children with lymphomas. Large prospective studies are needed to appreciate its real impact on patient management. [less ▲]

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