References of "Hermanns, Jean-François"
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See detailReactions cutanees a l'encre de tatouage.
FRANCHIMONT, Claudine ULg; Hermanns, Jean-François ULg; PIERARD, Gérald ULg

in Revue Médicale de Liège (2011), 66(7-8), 430-3

Ritual and artistic tattoos rely on the use of numerous pigments which are not all entirely inert once placed in the dermis. The compositions of some tattoo inks are identified. However, new but less well ... [more ▼]

Ritual and artistic tattoos rely on the use of numerous pigments which are not all entirely inert once placed in the dermis. The compositions of some tattoo inks are identified. However, new but less well identified compounds appear on the market. Allergic reactions can be present under different aspects. They may correspond to allergic contact dermatitis or to photodermatitis. Other reactions include allergic hypersensitivity reactions as well as lichenoid, granulomatous or pseudolymphoma reactions. Pulsed light and laser are typically used for regular tattoo removal. These procedures are not indicated in inflamed tattoos. Indeed, the pigment dispersed during photolysis may perpetuate the reaction. Pseudotattoos due to the stratum corneum staining are frequently responsible for photoeczema. [less ▲]

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See detailLes engelures, stigmates des affres climatiques.
Hermanns, Jean-François ULg; Caucanas, Marie ULg; PIERARD, Gérald ULg et al

in Revue Médicale de Liège (2010), 65(12), 688-90

Chilblain results from environmental nonfreezing cold exposure. It is a localized inflammatory lesion most frequently localized on the toes and fingers. Chilblains are often idiopathic, but they may be ... [more ▼]

Chilblain results from environmental nonfreezing cold exposure. It is a localized inflammatory lesion most frequently localized on the toes and fingers. Chilblains are often idiopathic, but they may be part of lupus erythematosus. [less ▲]

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See detailHedgehog ringworm in humans and a dog.
Pierard-Franchimont, Claudine; Hermanns, Jean-François ULg; Collette, C. et al

in Acta Clinica Belgica (2008), 64

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See detailLe pimecrolimus (Elidel) hors des sentiers battus.
Hermanns-Lê, Trinh ULg; Hermanns, Jean-François ULg; Thirion, Laurence et al

in Revue Médicale de Liège (2006), 61(4), 256-9

Pimecrolimus is an immune downregulator that belongs to the class of calcineurin inhibitors. Its efficacy is recognized for the topical treatment of the mild to moderate types of atopic dermatitis. In ... [more ▼]

Pimecrolimus is an immune downregulator that belongs to the class of calcineurin inhibitors. Its efficacy is recognized for the topical treatment of the mild to moderate types of atopic dermatitis. In addition, the drug shows activity in a series of other dermatitides. We report a review of the international literature about this topic. [less ▲]

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See detailMechanobiology and force transduction in scars developed in darker skin types.
Quatresooz, Pascale ULg; Hermanns, Jean-François ULg; Paquet, Philippe ULg et al

in Skin Research & Technology (2006), 12(4), 279-82

BACKGROUND: Scarring is a complex process involving many cell types, cytokines and biological pathways including mechanobiology. Some subtle mechanical properties of skin can be assessed by measuring the ... [more ▼]

BACKGROUND: Scarring is a complex process involving many cell types, cytokines and biological pathways including mechanobiology. Some subtle mechanical properties of skin can be assessed by measuring the speed of ultrasound shear wave propagation. The orientation of abnormal skin tension forces can be visualized, particularly in darker skin types, using dermoscopy showing distinct patterns of rete ridges' conformation. AIM: To assess some mechanobiological features of scars in darker skin types. PATIENTS AND METHODS: Large atrophic and hypertrophic surgical scars were examined on the trunk of 35 darker skin subjects. The surrounding skin was used as a comparator. Dermoscopic aspects were recorded. Resonance running time measurements (RRTM) were performed using a shear wave propagation device (Reviscometer). They were performed in four specific directions at given angles with regard to the long axis of the scar. The minimum, maximum and mean RRTM values were recorded at each site. RESULTS: Dermoscopy revealed patterns of melanin deposits in scars distinct from the normal honeycomb network seen in the surrounding skin. Hypertrophic scars showed a patchy pattern of large macular melanoderma dispersed in a lighter background. In these cases, low RRTM values were obtained with little variations according to the orientation of the measurements. By contrast, atrophic scars showed a streaky laddering melanotic pattern under dermoscopy. Higher RRTM values were often obtained, particularly in the transversal direction of the scars. Mechanical anisotropy was greater in the atrophic scars compared with the normal skin. DISCUSSION: Darker skin types represent a model for visualizing the main orientation of the epidermal rete ridges. A correlation was found between the pattern of melanized rete ridges of scars and the main orientation of the intrinsic forces in the skin. [less ▲]

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See detailGaia, lumière et biosphère.
Hermanns, Jean-François ULg; Hermanns-Lê, Trinh ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2005), 60 Suppl 1

Some aspects of life are tightly bound to light exposure. Photosynthesis, chronobiology and various manifestations of the socio-cultural behaviour are typical examples.

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See detailStriae distensae in darker skin types: the influence of melanocyte mechanobiology.
Pierard, Claudine ULg; Hermanns, Jean-François ULg; Hermanns-Lê, Trinh ULg et al

in Journal of Cosmetic Dermatology (2005), 4(3), 174-8

Introduction Striae distensae in White people are commonly described as being reddish at first and turning white in time. This dual perception has been challenged. Indeed, the color difference between ... [more ▼]

Introduction Striae distensae in White people are commonly described as being reddish at first and turning white in time. This dual perception has been challenged. Indeed, the color difference between striae distensae and their surrounding skin varies on a wide range in part depending upon typology. Aim To study striae nigrae that are found only in subjects of darker complexion. Materials and methods In the present study conducted in 44 darker skin adults, dermoscopy was combined to reflectance colorimetry. Results Striae nigrae exhibited hypermelanosis of the epidermal rete ridges crossing transversally the lesions in a laddering pattern. By contrast, striae albae showed only faint melanotic networks. Conclusions As striae distensae are in part under the influence of skin stretching, their colors are likely to be controlled by some mechanobiological process activating or inhibiting melanogenesis in people of darker complexion. No argument involving an inflammatory mechanism is supported by the present observations. [less ▲]

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See detailLe cas clinique du mois. Angiomyxome superficiel.
Quatresooz, Pascale ULg; Hermanns, Jean-François ULg; Legrain, A. et al

in Revue Médicale de Liège (2004), 59(3), 128-30

Some cutaneous neoplasms are seemingly harmless, but they may prove to be problematic due to their propensity to invade or to recur. We present 2 cases of superficial angiomyxoma.

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See detailJuvenile acanthosis nigricans and insulin resistance.
Hermanns-Lê, Trinh ULg; Hermanns, Jean-François ULg; Pierard, Gérald ULg

in Pediatric Dermatology (2002), 19(1), 12-4

Acanthosis nigricans in obese adolescents is frequently associated with hyperinsulinemia and insulin resistance. We report three cases of this condition. In the early stage the skin lesions appeared to be ... [more ▼]

Acanthosis nigricans in obese adolescents is frequently associated with hyperinsulinemia and insulin resistance. We report three cases of this condition. In the early stage the skin lesions appeared to be erythematous and pruritic, mimicking an inflammatory dermatitis. Dietary control and oral metformin hydrochloride markedly improved the lesions. Topical calcipotriol may also help to control the skin condition. [less ▲]

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See detailPrenons garde aux lésions kystiques cutanées. Du dérisoire au méritoire.
Hermanns-Lê, Trinh ULg; Hermanns, Jean-François ULg; Pierard, Claudine ULg et al

in Revue Médicale de Liège (2002), 57(5), 314-6

Cutaneous cystic-like lesions do not always correspond to real epithelial cysts. Indeed, the histological examination may identify another benign tumour. But, in some instances, the surprise may be ... [more ▼]

Cutaneous cystic-like lesions do not always correspond to real epithelial cysts. Indeed, the histological examination may identify another benign tumour. But, in some instances, the surprise may be greater. We report three patients in whom lesions suggested clinically small cysts. However, they were malignant neoplasms corresponding to a malignant fibrous histiocytoma, an epithelioid angiosarcoma and a metastatic adenocarcinoma, respectively. [less ▲]

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See detailAssessment of topical hypopigmenting agents on solar lentigines of Asian women.
Hermanns, Jean-François ULg; Petit, Ludivine; Pierard, Claudine ULg et al

in Dermatology : International Journal for Clinical & Investigative Dermatology (2002), 204(4), 281-6

BACKGROUND: So-called darkened age spots encompass distinct pathological processes. The efficacy of topical depigmenting agents is difficult to objectivate. OBJECTIVE: To assess the hypopigmenting effect ... [more ▼]

BACKGROUND: So-called darkened age spots encompass distinct pathological processes. The efficacy of topical depigmenting agents is difficult to objectivate. OBJECTIVE: To assess the hypopigmenting effect of three cosmetic formulations using objective biometrological methods. METHODS: 50 women of South-East Asian ancestry were enrolled in this pilot study. They had solar lentigines according to dermoscopic criteria. The lesions were treated by topical hypopigmenting formulations. Products were applied twice daily for 2 or 3 months. Assessments at 1-month intervals were made using narrow-band reflectance spectrophotometry, image analysis of video-recorded ultraviolet light reflection and photodensitometry- and image-analysis-assisted corneomelametry. RESULTS: A 20% azelaic acid formulation and another one containing 5% ascorbyl glucosamine, 1% kojic acid and alpha-hydroxyacid esters appeared inefficacious on solar lentigines. A stabilized soy extract showed a better although modest lightening effect when assessed by corneomelametry. The subclinical or faint mottled skin revealed by ultraviolet light examination better responded (p < 0.05) to treatments. CONCLUSION: Focal epidermal hyperpigmentation is better controlled by topical whitening agents when the increase in melanin content reflects a modest functional hyperactivity of melanocytes. [less ▲]

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See detailAnalytic Quantification of Phototype-Related Regional Skin Complexion
Hermanns, Jean-François ULg; Petit, L.; Hermanns-Lê, Trinh ULg et al

in Skin Research & Technology : Official Journal of International Society for Bioengineering & the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society For... (2001), 7(3), 168-71

BACKGROUND/AIMS: Narrow-band spectrophotometry that yields melanin (M) and erythema (E) indexes is a convenient method for assessing skin colour. The objective of the study was to assess the phenotype ... [more ▼]

BACKGROUND/AIMS: Narrow-band spectrophotometry that yields melanin (M) and erythema (E) indexes is a convenient method for assessing skin colour. The objective of the study was to assess the phenotype-associated body site differences in skin complexion. METHOD: The Mexameter MX16 was used to record the skin colour in 137 subjects. Evaluations were made on the inner arm, volar forearm, dorsal forearm and forehead. RESULTS: The inner arm and volar forearm had similar values for each of the colorimetric values. The dorsal forearm exhibited the highest M values, and the forehead had the highest E values. Significant positive linear correlations were found between M values from the distinct body sites. The E values showed a correlation only between the inner arm and the volar forearm. CONCLUSION: Regional skin colour differences are obvious. Sun-exposed skin does not react in the same way on the forearm and forehead. Regional variations in M can be predicted from the innate M value. In contrast, the regional variability in E is highly variable among subjects. [less ▲]

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See detailEffect of the 585 Nm Flashlamp-Pumped Pulsed Dye Laser for the Treatment of Keloids
Paquet, Philippe ULg; Hermanns, Jean-François ULg; Pierard, Gérald ULg

in Dermatologic Surgery (2001), 27(2), 171-4

BACKGROUND: Due to its potential effects on skin microcirculation and collagen metabolism, the 585 nm flashlamp-pumped pulsed dye laser has been proposed for treating abnormal scars. Indeed, one of the ... [more ▼]

BACKGROUND: Due to its potential effects on skin microcirculation and collagen metabolism, the 585 nm flashlamp-pumped pulsed dye laser has been proposed for treating abnormal scars. Indeed, one of the main problems with keloidal scars is their disfiguring erythematous color. OBJECTIVE: To assess the efficacy of the 585 nm pulsed dye laser on the appearance of keloids. METHODS: Eleven patients with skin phototypes II-IV and keloids were treated with the 585 nm pulsed dye laser. After one to three treatment sessions, clinical assessments of the scars were performed in combination with remittance spectroscopy measurements of the redness and melanin pigmentation. A group of nine keloids covered by silicone gel sheeting served as controls. Data were compared statistically. RESULTS: During laser treatments, a discrete decrease in redness of the scars was clinically reported. However, this improvement was not confirmed by the objective spectrophotometric data. No side effects, especially hyperpigmentation, were disclosed. The keloids redness was not improved in the control group. CONCLUSION: The 585 nm pulsed dye laser yields only minimal effects, if any, on the erythema of keloids. Similarly silicone gel sheeting does not modify the keloids redness. [less ▲]

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See detailRelativite de la prise en charge des cancers cutanes. Plaidoyer pour la synergie entre le medecin generaliste et le dermatologue-oncologue
Pierard, Gérald ULg; Pierard-Franchimont, Claudine ULg; Cornil, F. et al

in Revue Médicale de Liège (2000), 55(4), 247-252

The clinical diagnosis and treatment of cutaneous cancers represent a frequent situation in cancerology. About one third of all human cancers take their origin from the skin. The general practitioner and ... [more ▼]

The clinical diagnosis and treatment of cutaneous cancers represent a frequent situation in cancerology. About one third of all human cancers take their origin from the skin. The general practitioner and the dermatologist-oncologist play the key role in that field of health care. [less ▲]

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See detailLes mélanomes cutanés, un spectre de cancers émergents chez la femme en région wallonne
Pierard-Franchimont, Claudine ULg; Arrese Estrada, Jorge ULg; Cornil, F. et al

in Revue Médicale de Liège (1999), 54(5), 495-499

The Mosan Study Group of Pigmented Neoplasms was founded about 15 years ago. It has collected more than 20.000 cutaneous malignancies including melanoms and basal and squamous cell carcinomas. The ... [more ▼]

The Mosan Study Group of Pigmented Neoplasms was founded about 15 years ago. It has collected more than 20.000 cutaneous malignancies including melanoms and basal and squamous cell carcinomas. The incidence of these cancers in on the rise in Wallonia. In particular, malignant melanoms represent a spectrum of emerging cancers characterized by a proteiform biological outcome. They mostly affect young women. The major risk factor appears to be iterative and unwise ultraviolet exposures. The prevention of malenomas is basically founded on such a dogma and accordingly relies on sunscreens. However, controversies about their beneficial effects are rife and fueled by axiomas and contradictory sophisms. At the exception of surgery, the therapeutic options for the diverse types of melanomas do not yet fulfill the scope of evidence-based medicine. [less ▲]

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See detailHigh-Grade Pleomorphic T Cell Lymphoma with Restricted Involvement of Skin and Bone Marrow
Gautier, M. S.; Pierard, Gérald ULg; Andrien, Francine ULg et al

in Dermatology : International Journal for Clinical & Investigative Dermatology (1993), 186(4), 287-9

Pleomorphic T cell lymphoma of the medium to large cell type expressing CD30 antigen is a most aggressive peripheral T cell lymphoma. Currently, there is no satisfactory treatment available for this ... [more ▼]

Pleomorphic T cell lymphoma of the medium to large cell type expressing CD30 antigen is a most aggressive peripheral T cell lymphoma. Currently, there is no satisfactory treatment available for this neoplasm. We report the case of a woman with prominent skin and bone marrow involvement without detectable lymph node localization. This unusual presentation of disease responded well to polychemotherapy combined with autologous bone marrow transplantation. [less ▲]

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