References of "Hauwaert, Christian"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailHepatic alveolar echinococcosis
Delbecque, Katty ULg; Hayette, Marie-Pierre ULg; Jeukens, Thierry ULg et al

in Acta Gastro-Enterologica Belgica (2000, January), 63(1), 1

Detailed reference viewed: 50 (14 ULg)
Full Text
Peer Reviewed
See detailToxicité potentielle et utilisation pratique du méthotrexate dans la polyarthrite rhumatoïde
Kaye, O.; Ribbens, Clio ULg; Hauwaert, Christian ULg et al

in Médecine et Hygiène (1995)

Detailed reference viewed: 12 (0 ULg)
Full Text
Peer Reviewed
See detailLe méthotrexate en rhumatologie: une révolution thérapeutique
Kaye, O.; Ribbens, Clio ULg; Hauwaert, Christian ULg et al

in Revue Médicale de Liège (1995), 50(11), 453-457

Detailed reference viewed: 74 (1 ULg)
Peer Reviewed
See detailDétection et caractérisation antigènique des anticorps antinucleaires dans les connectivites
de Marneffe, P.; Malaise, Michel ULg; Deflandre, Etienne ULg et al

in Revue Médicale de Liège (1989), 44(19), 577-591

Detailed reference viewed: 30 (6 ULg)
Full Text
Peer Reviewed
See detailTraitement de la polyarthrite rhumatoïde: étude comparative de l'effect des immunoglobulines G éluées du placenta et de celui des veinoglobulines
Sany, J.; Clot, J.; Combe, B. et al

in Presse Médicale (1987), 16(15), 723-724

A double-blind multicenter study comparing the effect of placenta eluted IgG and venoglobulins in the treatment of rheumatoid arthritis was conducted in 113 hospitalized patients. Rheumatoid arthritis was ... [more ▼]

A double-blind multicenter study comparing the effect of placenta eluted IgG and venoglobulins in the treatment of rheumatoid arthritis was conducted in 113 hospitalized patients. Rheumatoid arthritis was severe, classical (92 cases) or definite (21 cases), seropositive in 87 cases, with nodules in 32 cases; the mean duration of the disease was 10 years. The majority of patients had previously received numerous slow-acting drugs without result or with side-effects. A statistically significant decrease of all the quantitative indices but one (grip strength) was obtained with both products on the 8th day of treatment; the effect of placenta eluted IgG was statistically superior for the number of swollen joints (P less than 0.025), Ritchie's index (P less than 0.0005) and some extra-articular manifestations. There was no significant decrease in associated treatments and biological parameters (erythrocyte sedimentation rate, rheumatoid factor). Tolerance was excellent; some cases of benign venulitis were observed; treatment was never discontinued on account of side-effects. Further placebo-controlled of each of these immunoglobulins of placental origin are needed for firm conclusions to be drawn. [less ▲]

Detailed reference viewed: 21 (0 ULg)
Full Text
Peer Reviewed
See detailConfirmative study of the effectiveness of thymopentin in active rheumatoid arthritis
Malaise, Michel ULg; Franchimont, P.; Hauwaert, Christian ULg et al

in Survey of Immunologic Research (1985), 4

Detailed reference viewed: 4 (0 ULg)
Full Text
Peer Reviewed
See detailTreatment of active rheumatoid arthritis with slow intravenous injections of thymopentin
Malaise, Michel ULg; Franchimont, P.; Bach-Andersen, R. et al

in Lancet (1985), 13(1), 832-836

41 patients with active rheumatoid arthritis entered a placebo-controlled double-blind randomised study in which 21 received slow intravenous injections (given in fractions over 10 min) of thymopentin ... [more ▼]

41 patients with active rheumatoid arthritis entered a placebo-controlled double-blind randomised study in which 21 received slow intravenous injections (given in fractions over 10 min) of thymopentin (TP·5) 50 mg 3 times a week for 3 consecutive weeks and 20 received placebo in the same way. After 3 weeks of treatment the TP-5 group showed improvement (p<O' 05 or p<O: 01) in all but one of the clinical variables tested. There was improvement in the number of joints painful at rest, the number of joints painful on motion, scores for tenderness on pressure and swollen joints, severity of pain on awakening and morning stiffness, and right-hand grip strength; left hand grip strength remained unchanged. In the placebo group, only morning stiffness improved significantly. [less ▲]

Detailed reference viewed: 8 (0 ULg)
Full Text
Peer Reviewed
See detailIn vivo studies on the mononuclear phagocyte system Fc receptor function in rheumatoid arthritis. Correlations with clinical and immunological variables
Malaise, Michel ULg; Foidart, J. B.; Hauwaert, Christian ULg et al

in Journal of Rheumatology (1985), 12(1), 33-42

The mononuclear phagocyte system Fc receptor function was assessed in 13 control subjects and 17 patients with rheumatoid arthritis (RA) by intravenous injection of IgG coated (IgG-RBC) or of heat-damaged ... [more ▼]

The mononuclear phagocyte system Fc receptor function was assessed in 13 control subjects and 17 patients with rheumatoid arthritis (RA) by intravenous injection of IgG coated (IgG-RBC) or of heat-damaged (HD-RBC) 99rnTc-Iabeled autologous erythrocytes. Although the clearance half-times of control and RA erythrocytes were not significantly different, the spleen to liver uptake ratios per surface area (S/Ls), determined by quantitative scintigraphic analysis, were significantly lower in RA patients than in controls. The S/Lswere significantly correlated with the Steinbrocker stages Ir = 0.92; p < 0.01), the disease duration (r = 0.73; p < 0.01) and the total immunoglobulin levels (r = 0.73; p < 0.01). The Clq binding activity of the sera was inversely correlated with the spleen (r = 0.90; p < 0.01) and liver uptakes (r = 0.73; p < 0.02). Our results therefore show an alteration of the Fc receptor function of splenic and hepatic mononuclear phagocytes in RA patients. [less ▲]

Detailed reference viewed: 11 (0 ULg)
Peer Reviewed
See detailInterim results on the clinical effects of i.v. administered thymopentin in active rheumatoid arthritis
Malaise, Michel ULg; Franchimont, P.; Hauwaert, Christian ULg et al

in International Journal of Clinical Pharmacology, Therapy and Toxicology (1984), 4(6), 451-457

Forty-one patients with active rheumatoid arthritis entered a controlled, double-blind, randomized study; 21 received prolonged i.v. injections (10 min) of thymopentin 50 mg 3 times a week for 3 ... [more ▼]

Forty-one patients with active rheumatoid arthritis entered a controlled, double-blind, randomized study; 21 received prolonged i.v. injections (10 min) of thymopentin 50 mg 3 times a week for 3 consecutive weeks; the other 20 received placebo under the same conditions. The groups were comparable at the start of the study. Statistical tests of changes within the treatment groups after 3 weeks showed that the improvement achieved in the thymopentin group was significant (p less than 0.05 or p less than 0.01) for each clinical parameter, except for left-hand grip strength. On the other hand, no significant improvement was observed for any parameter except morning stiffness in the patients on placebo. The intergroup comparison showed significant differences, favouring thymopentin over placebo treatment, in the Ritchie index, scores for swollen joints, assessment of severity of pain and scores for changes in the activity of the disease. Only minor side-effects were experienced in the two treatment groups. The present placebo-controlled double-blind study confirms the previous positive results achieved in open studies, i.e., the beneficial therapeutic effect of prolonged i.v. injections of thymopentin in patients with severe rheumatoid arthritis observed after 3 weeks of therapy. The drug appears to be safe at the dose regimen used. [less ▲]

Detailed reference viewed: 6 (0 ULg)