Microencapsulation of Erythromycin and Clarithromycin Using a Spray-Drying Technique; ; et al in Journal of Microencapsulation (1999), 16(5, Sep-Oct), 565-71 Previous methods of microencapsulation are unable to process particles smaller than 100 microm without organic solvents or the use of multistep processes. The present study investigates the feasiblity of ... [more ▼] Previous methods of microencapsulation are unable to process particles smaller than 100 microm without organic solvents or the use of multistep processes. The present study investigates the feasiblity of a one-step spray-drying process to microencapsulate erythromycin and clarithromycin, antibiotics known to have an unpleasant, bitter taste. Mixtures of clarithromycin (5% by weight) or erythromycin (30% by weight) with a biodegradable polymer were prepared and spray-dried under specific conditions of temperature and turbine speed. This process resulted in the microencapsulation of 80% of each drug as determined by high pressure liquid chromatography. Particle size ranged from 1 to 80 microm as determined by electron microscopy. These data show that microencapsulation of macrolides using a spray-drying technique is feasible. Spray-drying microencapsulation might be useful in the formulation of palatable oral suspensions of bitter tasting drugs. [less ▲] Detailed reference viewed: 62 (16 ULg) Microencapsulation Of Erythromycin And Clarithromycin Using A Spray-Drying Technique; ; et al in Journal of Microencapsulation (1999), 16(5), Detailed reference viewed: 16 (3 ULg) Relationship between physiologic conditions of Lactobacillus acidophilus growth and their viability after encapsulation by spray-drying.; ; et al Poster (1995, February) Detailed reference viewed: 8 (0 ULg) Microencapsulation of erythromycin and clarithromycin using a spray-drying technique.; ; et al Poster (1994, January) Detailed reference viewed: 21 (0 ULg) Microencapsulation of HIV antigen: Potential application of the spray-drying technique.; ; Goffinet, Gerhard et alPoster (1993, December) Detailed reference viewed: 5 (0 ULg) Antigen microencapsulation using a spray-drying technique.; ; et al Poster (1993, October) Detailed reference viewed: 10 (0 ULg) Relationship between physiologic conditions of Lactobacillus acidophilus growth and their viability after encapsulation by spray-drying.; ; et al Poster (1993, July) Detailed reference viewed: 2 (0 ULg) Lactobacillus Acidophilus microencapsulation by spray-drying.; ; et al Poster (1993, June) Detailed reference viewed: 5 (1 ULg) Acute functional iron deficiency in obese subjects during very-low-energy all- protein diet.; BEGUIN, Yves ; et alPoster (1992) Detailed reference viewed: 9 (1 ULg) Thrombocytopénie allergique à la nitrofurantoïneSautois, Brieuc ; ; et alin Revue Médicale de Liège (1991), 46 Nous rapportons le dixième cas de thrombocytopénie à la nitrofurantoïne. Trois épisodes successifs sont décrits chez la même patiente, s'accompagnant de frissons et d'une thrombocytopénie extrême. La ... [more ▼] Nous rapportons le dixième cas de thrombocytopénie à la nitrofurantoïne. Trois épisodes successifs sont décrits chez la même patiente, s'accompagnant de frissons et d'une thrombocytopénie extrême. La récupération hématologique est rapide à l'arrêt du médicament (retour à 150 000 plaquettes après 3 à 4 jours), en rapport avec la demi-vie plasmatique brève de la nitrofurantoïne. [less ▲] Detailed reference viewed: 68 (0 ULg) Allergic cross-reaction of teicoplanin and vancomycin; ; et al in Journal of Antimicrobial Chemotherapy (1991), 28 Detailed reference viewed: 18 (0 ULg) La leucémie a tricholeucocyte: 30 ans après.; ; Beguin, Yves et alin Revue Médicale de Liège (1989), 44(10), 358-64 Detailed reference viewed: 75 (3 ULg) |
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