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See detailMicroencapsulation of Erythromycin and Clarithromycin Using a Spray-Drying Technique
Zgoulli, S.; Grek, V.; Barre, G. et al

in Journal of Microencapsulation (1999), 16(5, Sep-Oct), 565-71

Previous methods of microencapsulation are unable to process particles smaller than 100 microm without organic solvents or the use of multistep processes. The present study investigates the feasiblity of ... [more ▼]

Previous methods of microencapsulation are unable to process particles smaller than 100 microm without organic solvents or the use of multistep processes. The present study investigates the feasiblity of a one-step spray-drying process to microencapsulate erythromycin and clarithromycin, antibiotics known to have an unpleasant, bitter taste. Mixtures of clarithromycin (5% by weight) or erythromycin (30% by weight) with a biodegradable polymer were prepared and spray-dried under specific conditions of temperature and turbine speed. This process resulted in the microencapsulation of 80% of each drug as determined by high pressure liquid chromatography. Particle size ranged from 1 to 80 microm as determined by electron microscopy. These data show that microencapsulation of macrolides using a spray-drying technique is feasible. Spray-drying microencapsulation might be useful in the formulation of palatable oral suspensions of bitter tasting drugs. [less ▲]

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See detailMicroencapsulation Of Erythromycin And Clarithromycin Using A Spray-Drying Technique
Zgoulli, S.; Grek, V.; Barre, G. et al

in Journal of Microencapsulation (1999), 16(5),

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See detailRelationship between physiologic conditions of Lactobacillus acidophilus growth and their viability after encapsulation by spray-drying.
Zgoulli, S.; Grek, V.; Roblain, D. et al

Poster (1995, February)

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See detailMicroencapsulation of erythromycin and clarithromycin using a spray-drying technique.
Grek, V.; Zgoulli, S.; Delcour, M. A. et al

Poster (1994, January)

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See detailMicroencapsulation of HIV antigen: Potential application of the spray-drying technique.
Grek, V.; Zgoulli, S.; Goffinet, Gerhard ULg et al

Poster (1993, December)

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See detailAntigen microencapsulation using a spray-drying technique.
Zgoulli, S.; Gilsoul, J. J.; Gerard, J. et al

Poster (1993, October)

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See detailRelationship between physiologic conditions of Lactobacillus acidophilus growth and their viability after encapsulation by spray-drying.
Zgoulli, S.; Grek, V.; Blanchet, I. et al

Poster (1993, July)

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See detailLactobacillus Acidophilus microencapsulation by spray-drying.
Zgoulli, S.; Gilsoul, J. J.; Gerard, J. et al

Poster (1993, June)

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See detailAcute functional iron deficiency in obese subjects during very-low-energy all- protein diet.
Grek, V.; BEGUIN, Yves ULg; Weber, G. et al

Poster (1992)

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See detailThrombocytopénie allergique à la nitrofurantoïne
Sautois, Brieuc ULg; Mélon, P.; Grek, V. et al

in Revue Médicale de Liège (1991), 46

Nous rapportons le dixième cas de thrombocytopénie à la nitrofurantoïne. Trois épisodes successifs sont décrits chez la même patiente, s'accompagnant de frissons et d'une thrombocytopénie extrême. La ... [more ▼]

Nous rapportons le dixième cas de thrombocytopénie à la nitrofurantoïne. Trois épisodes successifs sont décrits chez la même patiente, s'accompagnant de frissons et d'une thrombocytopénie extrême. La récupération hématologique est rapide à l'arrêt du médicament (retour à 150 000 plaquettes après 3 à 4 jours), en rapport avec la demi-vie plasmatique brève de la nitrofurantoïne. [less ▲]

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See detailAllergic cross-reaction of teicoplanin and vancomycin
Grek, V.; Andrien, F.; Collignon, J. et al

in Journal of Antimicrobial Chemotherapy (1991), 28

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See detailLa leucémie a tricholeucocyte: 30 ans après.
Grek, V.; Hay, F.; Beguin, Yves ULg et al

in Revue Médicale de Liège (1989), 44(10), 358-64

Detailed reference viewed: 75 (3 ULg)