References of "Grandfils, Christian"
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See detailTailored made degradable synthetic polymers for 3D (bio)printing
Grandfils, Christian ULg

Conference (2016, January 26)

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See detailDPSC colonization of functionalized 3D textiles
Ortiz, Marine; Rosales-Ibáñez, R; Pozos-Guillén, A. et al

in Journal of Biomedical Materials Research, Part B : Applied Biomaterials (2016), 10.1002/jbm.b.33609

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See detailDevelopment and characterization of bilayer films of FucoPol and chitosan
Ferreiraa, A.R.V.; Torres, C.A.V.; Freitas, F. et al

in Carbohydrate Polymers (2016), 147

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See detailAssessment of the adhesive properties of FucoPol, a bacterial polysaccharide
Araújo, D.; Alves, V.D.; Campo, J. et al

in International Journal of Biological Macromolecules (2016), 92

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See detailAdaptation of targeted nanocarriers to changing requirements in antimalarial drug delivery
Marques, J.; Valle-Delgado, J.; Urbán, P. et al

in Nanomedicine : Nanotechnology, Biology, and Medicine (2016)

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See detailSynthesis of hydrophilic CuInS2/ZnS quantum dots with different polymeric shells and study of their cytotoxicity and hemocompatibility
Speranskaya, Elena Sergeevna; Sevrin, Chantal ULg; De Saeger, Sarah et al

in ACS Applied Materials and Interfaces (2016), 6

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See detailComparison of commercial membranes tailored as 3D in vitro cell models
Romano, Ilaria ULg; Tilkin, Rémi ULg; Hubaux, Roland et al

Poster (2016)

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See detailIn vitro and in vivo evaluation of drug-eluting microspheres designed for transarterial chemoembolization therapy
Wang, Y.; Molin, D.; Sevrin, Chantal ULg et al

in International Journal of Pharmaceutics (2016), 503

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See detailStudy of cell growth on/in modified polymer matrices as scaffolds for tissue engineering
Markvicheva, E.; Drozdova, M.; Demina, T. et al

Poster (2016)

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See detailPolylactide-based microspheres prepared using solid-state copolymerized chitosan and D,L-lactide
Demina, Tatiana; Akopova, T.A.; Vladimirov, L.V. et al

in Materials Science and Engineering: A (2016), C59

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See detailHighly Luminescent Aqueous Ag2S Quantum Dots as New Generation Quantum Dots
Yağcı Acar, Havva Funda; Hocaoğlu, I.; Demir, F. et al

in Proceediing of the meeting (2015, March 09)

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See detailPolymeric synthetic antidote
Grandfils, Christian ULg; Sevrin, Chantal ULg; Flebus, Luca ULg

Patent (2015)

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See detailProduction of extracellular polysaccharide by Enterobacter A47 using cheese whey as the sole carbon source
Antunes, S.; Alves, V.D.; Grandfils, Christian ULg et al

in Proceeding of the meeting (2015, January 19)

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See detailCharacterization of the chitin-glucan complex extracted from Komagataella pastoris cell wall
Farinha, I.; Duarte, P.; Pimentel et al

in Proceeding of the meeting (2015, January 19)

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See detailLow molecular weight poly (2-dimethylamino ethylmethacrylate) polymers with controlled positioned fluorescent labeling: Synthesis, characterization and in vitro interaction with human endothelial cells.
Flebus, Luca ULg; Lombart, François ULg; Sevrin, Chantal et al

in International journal of pharmaceutics (2015), 478(1), 278-287

Poly (2-dimethylamino ethylmethacrylate) (PDMAEMA) is an attractive non-degradable polymer studied as nonviral vector for gene delivery but it can be also adopted for delivery of other biopharmaceutical ... [more ▼]

Poly (2-dimethylamino ethylmethacrylate) (PDMAEMA) is an attractive non-degradable polymer studied as nonviral vector for gene delivery but it can be also adopted for delivery of other biopharmaceutical drugs. As a parenteral carrier, the PDMAEMA free form (FF) might interact with tissues and cells. Few data are available on its selective internalization and efflux from cells, while the majority of studies published have followed the distribution of DNA complexed with PDMAEMA. In order to address polycation safety, the first aim was to synthesize by atom transfer radical polymerisation (ATRP) fluorescent labeled PDMAEMA of low molecular weight (Mw) (below 15kDa), controlling the position and density of fluorescein. The second goal was to analyze the possible difference in uptake and subcellular distribution of this labeled FF polycation between human umbilical vein endothelial cells (HUVEC) and hCMEC/D3 cells. These two cell lines have been chosen in order to detect selectivity towards the blood-brain barrier (BBB). In both cases, polycation was detected along the plasma membrane followed by progressive migration to the peri-nuclear region, where it overlapped with lysosomal structures. The analysis by fluorescence-activated cell sorting (FACS) of the PDMAEMA uptake by hCMEC/D3 cells showed a significant (p<0.05) inhibition (40%) in presence of 2-dexoxy-d-glucose inhibitor, a result supporting an energy-dependence mechanism(s). Cytotoxicity study showed that low Mw PDMAEMA (10kDa) lead to a minor cytotoxicity compared to the higher ones. As main conclusion this study highlights the similitude in cell trafficking of FF PDMAEMA and data previously reported for PDMAEMA/DNA complexes. [less ▲]

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See detailCyto/hemocompatible magnetic hybrid nanoparticles (Ag2SFe3O4) with luminesceence in the near-infrared region as promising theranostic materials
Hocaoglu, I.; Asik, A.; Ulusoy, U. et al

in Colloids and Surfaces B : Biointerfaces (2015), 133

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