References of "Gonce, Michel"
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See detailEpidemiology of major depression in Belgian parkinsonian patients
Vanderheyden, Jean-Emile; GONCE, Michel ULg; BOURGEOIS, Philip et al

in Acta Neurologica Belgica (2010), 110

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See detailChorea associated with anti-phospholipid antibodies: case report.
DEMONTY, Jean ULg; GONCE, Michel ULg; Ribai, P. et al

in Acta clinica Belgica (2010), 65(5), 350-3

A seventeen year-old boy developed left sided chorea in a few days, subsequently involving the four limbs. Although he presented a marfanoid phenotype, genetic analysis of the Fibrillin 1 was normal. The ... [more ▼]

A seventeen year-old boy developed left sided chorea in a few days, subsequently involving the four limbs. Although he presented a marfanoid phenotype, genetic analysis of the Fibrillin 1 was normal. The genes for familial chorea and Huntington's disease were also negative. Biological tests showed normal serum homocystein, but revealed very high levels of anti-beta2-GP1 IgG, anticardiolipin and lupus anticoagulant, which remained at similar values for a period of over three months. Electroencephalogram and cerebral magnetic resonance imaging (MRI) showed no abnormalities. Brain PET-scan disclosed bilateral striatal hypermetabolism. The patient was treated with methylprednisolone and low dose of acetylsalicylic acid. He improved markedly after six weeks of treatment, and choreic movements disappeared completely after two months. A control PET-scan performed at this time showed reversion of striated hypermetabolism to a normal pattern. The pathogenic aspects of this relatively rare case of chorea are discussed. [less ▲]

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See detailTreatments for progressing Parkinson's disease: a clinical case scenario study.
MAERTENS DE NOORDHOUT, Alain ULg; Santens, Patrick; Gerard, Jean-Marie et al

in Acta Neurologica Belgica (2009), 109(3), 189-99

OBJECTIVE: A 'case scenario' study on clinical decisions in progressing Parkinson's disease (PD) was developed to complement scientific evidence with the collective judgment of a panel of experts. METHODS ... [more ▼]

OBJECTIVE: A 'case scenario' study on clinical decisions in progressing Parkinson's disease (PD) was developed to complement scientific evidence with the collective judgment of a panel of experts. METHODS: The opinions of 9 experts in movement disorders on the appropriateness of 9 common pharmacological treatments for 33 hypothetical patient profiles were compared to those of 14 general neurologists. Before rating the case scenarios, all participants received a document integrating European and US guidelines for the treatment of patients with advanced PD. Case scenarios showing disagreement or with inconsistencies in appropriateness ratings were discussed at a feedback meeting. A tool for interactive discussion on the clinical case scenarios included was developed based on the outcome of the study. RESULTS: Current guidelines are often insufficient to adequately guide the management of patients with progressing PD. The case scenario study did not reveal major differences in opinions between experts in movement disorders and general neurologists about the appropriateness of certain drug choices for specific case scenarios. However in about 1 out of 5 treatment decisions where experts stated appropriateness or inappropriateness, the general neurologists panel had no or dispersed opinions. CONCLUSIONS: This study reveals more uncertainty about treatment of advanced PD in general neurologists compared with experts in movement disorders and underlines the need for additional support for guiding treatment decisions in clinical practice. [less ▲]

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See detailDystonies cervicales
DELVAUX, Valérie ULg; GONCE, Michel ULg

Article for general public (2002)

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See detailPainful legs and moving toes: a syndrome with different physiopathologic mechanisms.
Schoenen, Jean ULg; Gonce, Michel ULg; Delwaide, P.

in Neurology (1984), 34(8), 1108-12

Six patients with the syndrome of "painful legs and moving toes" were studied. Although clinical differences were nonspecific, the EMG disclosed two subgroups: one with a simple, erratic pattern of ... [more ▼]

Six patients with the syndrome of "painful legs and moving toes" were studied. Although clinical differences were nonspecific, the EMG disclosed two subgroups: one with a simple, erratic pattern of spontaneous activities in foot and leg muscles, and the other with a complex alternating pattern in antagonistic muscles. In the first group, the physiopathologic mechanism is thought to act in the periphery: in the lumbar roots when local anesthesia of the posterior tibial nerve suppresses spontaneous discharges, or in the nerve trunk when it is ineffective. In the second group, the symptomatology may be generated centrally, implying a more general disturbance of sensorimotor control. [less ▲]

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See detailSuccessful treatment of hemiballismus with progabide, a new GABA-mimetic agent.
Gonce, Michel ULg; Schoenen, Jean ULg; Charlier, M. et al

in Journal of Neurology (1983), 229(2), 121-4

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See detailPainful legs and moving toes: démembrement clinique et physiopathologique du syndrome
Schoenen, Jean ULg; Gonce, Michel ULg; Delwaide, P. J.

in Acta Neurologica Belgica (1983), 83

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