References of "Gol-Winkler, Rose"
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See detailSpecific transcription factors regulate the c-erbB2 expression in the tumor BT-474 mammary cells.
Grooteclaes, Madeleine; Pasleau, Françoise ULg; Gol-Winkler, Rose

Conference (1995, March 24)

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See detailSpecific transcription factors of the tumor BT-474 mammary cells regulate the c-erbB2 gene expression.
Grooteclaes, Madeleine; Pasleau, Françoise ULg; Gol-Winkler, Rose

Conference (1994, December 22)

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Peer Reviewed
See detailThe 6 kb c-erbB2 promoter contains positive and negative regulatory elements functional in human mammary cell lines.
Grooteclaes, Madeleine; Pasleau, Françoise ULg; Dijkmans, Huguette et al

Conference (1994, September)

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See detailRégulation de l'expression de l'oncogène c-erbB2 dans les cancers mammaires humains.
Grooteclaes, Madeleine; Pasleau, Françoise ULg; Dijkmans, Huguette et al

Conference (1994, May 06)

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See detailThe c-erbB2 upstream regulatory region contains positive and negative cis-acting elements differentially active in human mammary tumor cell lines.
Grooteclaes, Madeleine; Pasleau, Françoise ULg; Berzi, Paulette et al

Conference (1994, January 29)

Detailed reference viewed: 11 (2 ULg)
See detailBreast-specific expression of erbB2-LUC reporter genes.
Pasleau, Françoise ULg; Grooteclaes, Madeleine; Berzi, Paulette et al

Conference (1993, November 11)

Detailed reference viewed: 10 (1 ULg)
See detailMolecular alterations in breast cancers : deregulation of c-erbB2 gene expression.
Gol-Winkler, Rose; Pasleau, Françoise ULg; Grooteclaes, Madeleine et al

Conference (1993, September)

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See detailExpression of the C-Erbb2 Gene in the Bt474 Human Mammary Tumor Cell Line: Measurement of C-Erbb2 Mrna Half-Life
Pasleau, Françoise ULg; Grooteclaes, Madeleine; Gol-Winkler, Rose

in Oncogene (1993), 8(4), 849-54

BT474 and SK-BR-3 mammary adenocarcinoma cells contain eight copies of the c-erbB2 gene but overexpress the mRNA 80 times over the levels measured in normal breast or in the HBL-100 cell line. Using ... [more ▼]

BT474 and SK-BR-3 mammary adenocarcinoma cells contain eight copies of the c-erbB2 gene but overexpress the mRNA 80 times over the levels measured in normal breast or in the HBL-100 cell line. Using Northern blot analysis and molecular titration based on RNAase protection assay, the decrease in the c-erbB2 mRNA level was monitored in BT474 cells treated with actinomycin D from 1 up to 24 h. The c-erbB2 degradation rate during the first 12 h corresponds to a calculated c-erbB2 mRNA half-life of approximately 7 h. Forty percent of the mRNA present in the cells before treatment remains undegraded after transcription has been blocked for 24 h. Pretreatment with cycloheximide results in complete mRNA degradation in 24 h, suggesting that labile proteins stabilize part of the c-erbB2 mRNA population. Comparison with the c-erbB2 mRNA turnover in HBL-100 'normal' cells indicated that the accumulation of the c-erbB2 gene product in the tumor cells is not the result of stabilization of the messenger. Rather, it is correlated with an increased rate of c-erbB2 mRNA transcription as indicated by run-on transcription assays. Both BT474 and SK-BR-3 tumor cell lines were found to synthesize 20-40 times more c-erbB2 mRNA than HBL-100 cells. [less ▲]

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See detailCaractérisation des altérations moléculaires responsables de la surexpression du gène c-erbB2 dans les cancers du sein.
Grooteclaes, Madeleine; Pasleau, Françoise ULg; Dijkmans, Huguette et al

Conference (1993, March 26)

Detailed reference viewed: 17 (4 ULg)
Peer Reviewed
See detailEtude de l'expression de l'oncogène c-erbB2 dans les cellules épithéliales mammaires humaines "normales" HBL-100 et tumorales BT-474.
Grooteclaes, Madeleine; Pasleau, Françoise ULg; Gol-Winkler, Rose

Conference (1992, November 24)

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See detailExpression transitoire du promoteur c-erbB2 dans les cellules épithéliales mammaires normales et tumorales en culture.
Grooteclaes, Madeleine; Pasleau, Françoise ULg; Dijkmans, Huguette et al

Conference (1992, February)

Detailed reference viewed: 34 (1 ULg)
Peer Reviewed
See detailLes oncogènes dans les cancers du sein.
Gol-Winkler, Rose; Pasleau, Françoise ULg; Dijkmans, Huguette

Conference (1990)

Detailed reference viewed: 52 (2 ULg)