References of "Gluckman, E"
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See detailOutcomes of UCB transplantation are comparable in FLT3+ AML: Results of CIBMTR, eurocord and EBMT collaborative analysis.
Ustun, C.; Giannotti, F.; Zhang, M.-J. et al

in Leukemia : Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K (2017)

Allogeneic hematopoietic cell transplantation (HCT) from siblings or unrelated donors (URD) during complete remission (CR) may improve leukemia-free survival (LFS) in FLT3+ acute myeloid leukemia (AML ... [more ▼]

Allogeneic hematopoietic cell transplantation (HCT) from siblings or unrelated donors (URD) during complete remission (CR) may improve leukemia-free survival (LFS) in FLT3+ acute myeloid leukemia (AML) that has poor prognosis due to high relapse rates. Umbilical cord blood (UCB) HCT outcomes are largely unknown in this population. We found that compared with sibling HCT, relapse risks were similar after UCB (n=126), (HR 0.86, P=0.54) and URD (n=91) (HR 0.81, P=0.43). UCB HCT was associated with statistically higher non-relapse mortality compared with sibling HCT (HR 2.32, P=0.02), but not vs URD (HR 1.72, P=0.07). All three cohorts had statistically not significant 3-year LFS: 39% (95% CI 30-47) after UCB, 43% (95% CI 30-54) after sibling, and 50% (95% CI 40-60) after URD. Chronic GVHD rates were significantly lower after UCB compared with either sibling (HR 0.59, P=0.03) or URD (HR 0.49, P=0.001). Adverse factors for LFS included high leukocyte count at diagnosis and HCT during CR2. UCB is a suitable option for adults with FLT3+AML in the absence of an HLA-matched sibling and its immediate availability may be particularly important for FLT3+ AML where early relapse is common thus allowing HCT in CR1 when outcomes are best.Leukemia accepted article preview online, 25 January 2017. doi:10.1038/leu.2017.42. [less ▲]

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See detailEffect of volume reduction of cord blood units before storage on transplantation outcomes: a retrospective analysis of Eurocord-EBMT and Netcord
SACCARDI, R; Tucunduva, L; Ruggeri, A et al

in Bone Marrow Transplantation (2013, April 01), 48

In this Registry study, manipulation of the CBUs aimed at volume reduction was not shown to infl uence the clinical outcome, indicating a satisfactory validation of the associated technologies across the ... [more ▼]

In this Registry study, manipulation of the CBUs aimed at volume reduction was not shown to infl uence the clinical outcome, indicating a satisfactory validation of the associated technologies across the banks. Cells viability assessment methodology varied among banks. Further eff orts to standardize the quality controls before CBU release are needed. [less ▲]

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See detailEffect of HLA-matching recipients to donor non-inherited maternal antigens on outcomes after mismatched umbilical cord blood transplantation for hematologic malignancy
Rocha, V; Spellman, S; Zhang, MJ et al

in Biology of Blood & Marrow Transplantation (2012)

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See detailFamily-directed umbilical cord blood banking.
GLUCKMAN, E; ROCHA, V; BAUDOUX, Etienne ULg et al

in Haematologica (2011), 96(11), 1700-17007

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See detailUnrelated cord blood transplantation in adults with myelodysplasia or secondary acute myeloblastic leukemia : a survey on behalf of Eurocord and CLWP of EBMT
Robin, M.; Sanz, G. F.; Ionescu, I. et al

in Leukemia : Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K (2011), 25

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See detailKIR-ligand incompatibility in the Graft-versus-host direction improves outcome after umbilical cord blood transplantation for acute leukemia
Willemze, R.; Rodrigues, C. A.; Labopin, M. et al

in Leukemia : Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K (2009), 23

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