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See detailLevels of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and polychlorinated biphenyls in human milk from different regions of France
Focant, Jean-François ULg; Fréry, N; Bidondo, ML et al

in Science of the Total Environment (2013), 452-453

Wereport on the pilot study carried out before the start of the Elfe project (French longitudinal study from childhood). A total of 44 samples of mature human milk were collected at home 8 weeks after ... [more ▼]

Wereport on the pilot study carried out before the start of the Elfe project (French longitudinal study from childhood). A total of 44 samples of mature human milk were collected at home 8 weeks after delivery. A total of 7 polychlorinated dibenzo-p-dioxins (PCDDs), 10 polychlorinated dibenzofurans (PCDFs), 12 dioxin-like (DL) polychlorinated biphenyls (PCBs), and 6 non dioxin-like (NDL)-PCBs were measured. For total TEQ (PCDD/Fs and DL-PCBs), the geometric mean concentration was 17.81 pg TEQWHO05/g lipids. Relative PCDD, PCDF, and DL-PCB contributions to the arithmetic mean TEQWHO05 were 38%, 18%, and 44%, respectively. The use of TEFWHO05 instead of TEFWHO98 resulted in a 27% reduction of the total TEQ value. Although PCDD levels did not significantly change (less than 0.5% increase), PCDF and DL-PCB levels both decreased by 35% and 38%, respectively. Levels have been compared to data obtained during a previous non-reported national study conducted in 1998 (TEFWHO98) in French lactaria (n = 244). The mean of PCDD/Fs has decreased about 39.4% (18.8 pg TEQWHO98/g lipids in 1998 vs 11.4 pg TEQWHO98/g lipids in pilot study), respectively 41.5% for PCDDs (10.6 pg TEQWHO98/g lipids in 1998 vs 6.2 pg TEQWHO98/g lipids in pilot study) and 36.7% for PCDFs (7.9 pg TEQWHO98/g lipids in 1998 vs 5.0 pg TEQWHO98/g lipids in pilot study). For the sum of the 6 NDL-PCBs, the 2007 geometric mean concentration in milk was 176.3 ng/g lipids. The arithmetic mean lipid concentration in 2007 breast milk was 26.4 g/l (range from 6.0 to 46.7 g/l). A PCDD/F and DL-PCB daily intake was estimated to be 62.3 pg TEQWHO05/kg body weight per day (85.0 pg TEQWHO98/kg bodyweight per day) for a baby of 5 kg of bodyweight fed daily with 700 ml of maternal milk containing 25 g/l of lipids. [less ▲]

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See detailDioxins in Human Milk from Different Regions of France: Pilot of the French Longitudinal Study of Children (ELFE)
Vandentoren, S; Frery, N; Bidondo, ML et al

in Organohalogen Compounds (2011), 73

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See detailExposure factors influencing serum dioxin concentrations in the French dioxin and incinerators study
Frery, N.; Zeghnoun, A.; Sarter, H. et al

in Organohalogen Compounds (2007), 69

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See detailConfounding factors influencing serum dioxin concentrations in the French dioxin and incinerators study
Frery, N.; Zegnoun, N.; Sarter, H. et al

in Organohalogen Compounds (2007), 69

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See detailDealing with the non-detected and non-quantified data. The example of the serum dioxin data in the French dioxin and incinerators study
Zeghnoun, A.; Pascal, M.; Frery, N. et al

in Organohalogen Compounds (2007), 69

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See detailDietary habits and self-production of foods of individuals participating in the French dioxin and incinerators study
Grange, D.; Volatier, J. L.; Frery, N. et al

in Organohalogen Compounds (2007), 69

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See detailFactors explaining variation in serum dioxin concentrations for the specific congeners in the French dioxin and incinerators study
Zeghnoun, A.; Frery, N.; Volatier, J. L. et al

in Organohalogen Compounds (2007), 69

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See detailData quality of the serum analysis of PCDD, PCDF and PCB in the French dioxin and incinerators study
Pascal, M.; Eppe, Gauthier ULg; Zeghnoun, A. et al

in Organohalogen Compounds (2007), 69

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