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See detailCharacterization of a novel IMP-28 metallo-β-lactamase from a Spanish Klebsiella oxytoca clinical isolate
Pérez-Llarena, FJ; Fernández, A; Zamorano, L et al

in Antimicrobial Agents and Chemotherapy (2012), 56(8), 4540-3

An isolate of Klebsiella oxytoca carrying a novel IMP metallo-β-lactamase was discovered in Madrid, Spain. The bla(IMP-28) gene is part of a chromosomally located class I integron. The IMP-28 k(cat)/K(m ... [more ▼]

An isolate of Klebsiella oxytoca carrying a novel IMP metallo-β-lactamase was discovered in Madrid, Spain. The bla(IMP-28) gene is part of a chromosomally located class I integron. The IMP-28 k(cat)/K(m) values for ampicillin, ceftazidime, and cefepime and, to a lesser extent, imipenem and meropenem, are clearly lower than those of IMP-1. The His306Gln mutation may induce important modifications of the L3 loop and thus of substrate accessibility and hydrolysis and be the main reason for this behavior. [less ▲]

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See detailMultisite Observations of delta Scuti Stars 7 Aql and 8 Aql (a New delta Scuti Variable): The Twelfth STEPHI Campaign in 2003
Fox Machado, L.; Michel, Eric; Pérez Hernández, F. et al

in Astronomical Journal (The) (2007), 134

We present an analysis of the pulsation behavior of the delta Scuti stars 7 Aql (HD 174532) and 8 Aql (HD 174589), a new variable star, observed in the framework of the STEPHI XII campaign during 2003 ... [more ▼]

We present an analysis of the pulsation behavior of the delta Scuti stars 7 Aql (HD 174532) and 8 Aql (HD 174589), a new variable star, observed in the framework of the STEPHI XII campaign during 2003 June and July; 183 hr of high-precision photometry were acquired by using four-channel photometers at three sites on three continents during 21 days. The light curves and amplitude spectra were obtained following a classical scheme of multichannel photometry. Observations in different filters were also obtained and analyzed. Six and three frequencies have been unambiguously detected above a 99% confidence level in the range 190-300 muHz and 100-145 muHz in 7 Aql and 8 Aql, respectively. A comparison of observed and theoretical frequencies shows that 7 Aql and 8 Aql may oscillate with p-modes of low radial orders, typical among delta Scuti stars. In terms of radial oscillations the range of 8 Aql goes from n=1 to 3, while for 7 Aql the range spans from n=4 to 7. Nonradial oscillations have to be present in both stars as well. The expected range of excited modes according to a nonadiabatic analysis goes from n=1 to 6 in both stars. [less ▲]

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See detailPrimary Systemic Amyloidosis - A report of 2 cases
Dezfoulian, Bita ULg; Arrese Estrada, Jorge ULg; Fernandez, A. et al

in Dermatology : International Journal for Clinical & Investigative Dermatology (1996), 192

We report 2 cases of primary systemic amyloidosis. A monoclonal gammopathy was confirmed at the postmortem examination of the first patient. An extensive search for evidence of chronic infection ... [more ▼]

We report 2 cases of primary systemic amyloidosis. A monoclonal gammopathy was confirmed at the postmortem examination of the first patient. An extensive search for evidence of chronic infection, inflammation, neoplasms and paraproteinemia was conclusively negative in the other patient. The recognition of cutaneous signs of primary systemic amyloidosis is crucial to insure a rapid management aimed at postponing the fatal issue of the disease. [less ▲]

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