   Functional nanogels as platforms for imparting antibacterial, antibiofilm, and antiadhesion activities to stainless steelFaure, Emilie  ; Falentin, Céline ; Svaldo Lanero, Tiziana et alin Advanced Functional Materials (2012), 22(24), 5271-5282 In this work, long-term antibacterial, antiadhesion, and antibiofilm activities are afforded to industrial stainless steel surfaces following a green and bio-inspired strategy. Starting from catechol ... [more ▼] In this work, long-term antibacterial, antiadhesion, and antibiofilm activities are afforded to industrial stainless steel surfaces following a green and bio-inspired strategy. Starting from catechol bearing synthetic polymers, the film cross-linking and the grafting of active (bio)molecules are possible under environmentally friendly conditions (in aqueous media and at room temperature). A bio-inspired polyelectrolyte, a polycation-bearing catechol, is used as the film-anchoring polymer while a poly(methacrylamide)-bearing quinone groups serves as the cross-linking agent in combination with a polymer bearing primary amine groups. The amine/quinone reaction is exploited to prepare stable solutions of nanogels in water at room temperature that can be easily deposited to stainless steel. This coating provides quinonefunctionalized surfaces that are then used to covalently anchor active (bio) molecules (antibiofi lm enzyme and antiadhesion polymer) through thiol/ quinone reactions. [less ▲] Detailed reference viewed: 91 (22 ULg)Antibacterial polyelectrolyte micelles for coating stainless steelFalentin, Céline ; Faure, Emilie ; Svaldo Lanero, Tiziana et alin Langmuir (2012), 28(18), 7233-7241 In this study, we report on the original synthesis and characterization of novel antimicrobial coatings for stainless steel by alternating the deposition of aqueous solutions of positively charged ... [more ▼] In this study, we report on the original synthesis and characterization of novel antimicrobial coatings for stainless steel by alternating the deposition of aqueous solutions of positively charged polyelectrolytes micelles doped with silver based nanoparticles with a polyanion. The micelles are formed by electrostatic interaction between two oppositely charged polymers, a polycation bearing 3,4-dihydroxyphenylalanine units (DOPA, a major component of natural adhesives) and a polyanion (poly(styrene sulfonate), PSS) without using any block copolymer. DOPA units are exploited for their well-known ability to anchor to stainless steel and to form and stabilize biocidal silver nanoparticles (Ag0). The chlorine counter-anion of the polycation forms and stabilizes biocidal silver chloride nanoparticles (AgCl). We demonstrate that two layers of micelles (alternated by PSS) doped by silver particles are enough to impart to the surface a strong antibacterial activity against Gram-negative E. coli. Moreover, micelles that are reservoirs of biocidal Ag+ can be easily reactivated after depletion. This novel water-based approach is convenient, simple and attractive for industrial applications. [less ▲] Detailed reference viewed: 75 (9 ULg)Molecular biomimetics applied to medical devicesVan de Weerdt, Cécile ; ; Vreuls, Christelle et alPoster (2012, May 05) Detailed reference viewed: 32 (14 ULg)Molecular biomimetics applied to medical devicesVan de Weerdt, Cécile ; Vreuls, Christelle ; Genin, Alexis et alPoster (2012, April 18) Detailed reference viewed: 23 (10 ULg) A water-based antibacterial nanohybrid solution for coating stainless steelFalentin, Céline ; Faure, Emilie ; Svaldo Lanero, Tiziana et alConference (2011, June 28) Detailed reference viewed: 39 (5 ULg) |
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