References of "Dubruel, Peter"
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See detailpH-responsive flower-type micelles formed by a biotinylated poly(2-vinylpyridine)-block-poly(ethylene-oxide)-block-poly(ε-caprolactone) triblock copolymer
Van Butsele, Kathy ULg; Cajot, Sébastien ULg; Van Vlierberghe, Sandra et al

in Advanced Functional Materials (2009), 19(9), 1416-1425

In the present work, a method is proposed to assemble pH-responsive, flower-like micelles that can expose a targeting unit at their periphery upon a decrease in pH. The micelles are composed of a novel ... [more ▼]

In the present work, a method is proposed to assemble pH-responsive, flower-like micelles that can expose a targeting unit at their periphery upon a decrease in pH. The micelles are composed of a novel biotinylated triblock copolymer of poly(-caprolactone)-block-poly(ethylene oxide)-block-poly(2-vinylpyridine) (PCL-b-PEO-b-P2VP) and the non-biotinylated analogue. The block copolymers are synthesized by sequential anionic and ring-opening polymerization. The pH-dependent micellization behaviour in aqueous solution of the triblock copolymers developed is studied using dynamic light scattering, zeta potential, transmission electron microscopy (TEM), and fluorimetric measurements. The shielding of the biotin at neutral pH and their availability at the micelle surface upon protonation is established by TEM and surface plasmon resonance with avidin and streptavidin-coated gold surfaces. The preliminary stealthy behavior of these pH-responsive micelles is examined using the complement activation (CH50) test. [less ▲]

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See detailElectrografting of Poly(ethylene glycol) Acrylate : A One-Step Strategy for the Synthesis of Protein-Repellent Surfaces
Gabriel, Sabine ULg; Dubruel, Peter; Schacht, Etienne et al

in Angewandte Chemie (International ed. in English) (2005), 44(34), 5505-5509

Electrografting of acrylate end-capped poly(ethylene glycol) (PEG) is an important technique for the one-step coating of electroconductive substrates by an adherent hydrophilic coating (see figure). This ... [more ▼]

Electrografting of acrylate end-capped poly(ethylene glycol) (PEG) is an important technique for the one-step coating of electroconductive substrates by an adherent hydrophilic coating (see figure). This technique is very efficient for the production of new protein-repellent surfaces. [less ▲]

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See detailPreparation of reactive surfaces by electrografting: a route to biosensors
Gabriel, Sabine ULg; Jérôme, Christine ULg; Jérôme, Robert ULg et al

Poster (2004, May 27)

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