References of "Donneau, Anne-Françoise"
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See detailScreening for the metabolic syndrome in subjects with migraine
Streel, Sylvie ULg; Donneau, Anne-Françoise ULg; Dardenne, Nadia ULg et al

in Cephalalgia : An International Journal of Headache (2016)

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See detailEfficacy of the RemoweLL cardiotomy reservoir for fat and leucocyte removal from shed mediastinal blood: a randomized controlled trial.
LAGNY, Marc-Gilbert ULg; GOTHOT, André ULg; HANS, Grégory ULg et al

in Perfusion (2016)

Efficacy of the RemoweLL cardiotomy reservoir for Fat and Leucocyte removal from shed mediastinal blood: a randomized controlled trial. ABSTRACT (176 words) Introduction Re-transfusion of lipid particles ... [more ▼]

Efficacy of the RemoweLL cardiotomy reservoir for Fat and Leucocyte removal from shed mediastinal blood: a randomized controlled trial. ABSTRACT (176 words) Introduction Re-transfusion of lipid particles and activated leucocytes with shed mediastinal blood (SMB) can aggravate cardiopulmonary bypass-associated inflammation and increase the embolic load. This study evaluated the fat and leucocyte removal capacity of the RemoweLL cardiotomy reservoir. Methods Forty-five patients undergoing elective on-pump cardiac surgery were randomly allocated to filtration of SMB using the RemoweLL or the Admiral cardiotomy reservoir. The primary outcome was the drop in leucocytes and lipid particles obtained with the two filters. The effect of the filters on other blood cells and inflammatory mediators such as myeloperoxidase (MPO) was also assessed. Results The RemoweLL cardiotomy filter removed 16.5 % of the leucocytes (P < 0.001) while no significant removal of leucocytes was observed with the Admiral (P = 0.48). The percentage reductions in lipid particles were similar in the two groups (26% vs 23 %, P = 0.2). Both filters similarly affected the level of MPO (P = 0.71). Discussion The RemoweLL filter more effectively removed leucocytes from SMB than the Admiral. It offered no advantage in term of lipid particle clearance. [less ▲]

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See detailEffectiveness of High Intensity Radial Shock Wave Therapy in The Treatment of Chronic Plantar Fasciitis
Demoulin, Christophe ULg; Vanderthommen, Marc ULg; Fromm, Aurélien et al

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(Suppl. 1 No. 2), 733

Introduction: Literature is scarce concerning the effectiveness of high dose radial extracorporeal shock wave therapy (ESWT). Therefore, the aim of this study was to investigate its effectiveness on pain ... [more ▼]

Introduction: Literature is scarce concerning the effectiveness of high dose radial extracorporeal shock wave therapy (ESWT). Therefore, the aim of this study was to investigate its effectiveness on pain, function and pressure pain threshold in patients with chronicplantar fasciitis (PF). Materials and Methods: Patients with a diagnosis of chronic (pain lasting for more than 3 months) uni- or bilateral PF with a history of failed conservative treatment were included. After a 6-week control period during which no treatment occurred, a 2-week treatment period followed by a three weeks of rest (cicatrization phase) was provided. The treatment period consisted of three radial ESWT sessions (2000 impulses of 10 Hz frequency per session with an energy flux density of 0,275mJ/mm2) separated by a one-weekinterval. Patient assessments (pain intensity, foot function and pressure pain threshold (PPT) at the site of maximum local tenderness disability) were conducted at baseline, after the 6-week control phase (pre-treatment) and at the end of the cicatrization phase (post-treatment). Results: Thirty patients (19 women (63.3%)) with chronic PF and a mean age of 51.9±11 years were included in the present study. No drop-out occurred throughout the study period. No changes were observed at the pre-treatment assessment session except for pain intensity which decreased slightly but significantly (P<0.05). At the post-treatment session, highly significant (P<0.001) and clinically meaningful changes occurred for pain intensity (-34%), foot function score (-60%) and PPT (+68%). Conclusions: The present study suggests that high dose radial ESWT is a feasible and effective way to quickly and significantly decrease pain and disability in most patients with chronic PF. [less ▲]

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See detailEffects of twelve weeks of aerobic or strength training in addition to standard care in Parkinson’s disease: a controlled study
Demonceau, Marie ULg; MAQUET, Didier ULg; Jidovtseff, Boris ULg et al

in European Journal of Physical and Rehabilitation Medicine (2016), 52

BACKGROUND: Physical exercises in addition to standard care (SC) in patients with Parkinson’s disease (PD) are now common practice in many care units. However, exercises can cover a wide range of ... [more ▼]

BACKGROUND: Physical exercises in addition to standard care (SC) in patients with Parkinson’s disease (PD) are now common practice in many care units. However, exercises can cover a wide range of interventions, and the specific effects of different interventions still deserve to be further investigated. AIM: To compare the effects of 12 weeks of two different types of physical exercises with SC in patients suffering from PD. DESIGN: Pseudo-randomized controlled trial. SETTING: University laboratory for outcomes, University Hospital Centre for interventions. POPULATION: Fifty-two outpatients suffering from mild to moderate PD at baseline. METHODS: Participants were allocated to 3 groups: the strength training (ST) group performed individualized upper and lower limbs strength training, the aerobic training (AE) group performed tailored gradual aerobic cycling, and the third group received SC. The effects of the interventions on body function were assessed by measuring isokinetic concentric peak torque for knee extension and flexion, peak oxygen consumption (VO2peak) and peak work load (PWL) during an incremental maximal cycling test. Changes in mobility were evaluated from spatial-temporal gait features measured by mean of an accelerometer system and the six-minute walk distance (6mwd) test. We used questionnaires to estimate health-related quality of life and habitual physical activity. RESULTS: No significant changes in any outcome measures occurred in the SC group. More than 80% of the participants adequately completed the AE and the ST interventions. The ST group significantly improved all peak torque measures (p≤0.01), except knee extension in the least affected side (p=0.13). This group also improved the PWL (p=0.009) and 6mwd (p=0.03). The AE group improved the VO2peak (p=0.02) and PWL (p<0.001). CONCLUSION: Physical fitness in patients with PD rapidly improved in compliance with training specificities, but better fitness hardly translated into better mobility and health-related quality of life. CLINICAL REHABILITATION IMPACT: Physiotherapists can efficiently propose physical conditioning to patients with mild to moderate PD, but these interventions are insufficient to improve gait and participation. Notwithstanding, ST is an efficient intervention for improving walking capacity. [less ▲]

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See detailDelayed neuroendocrine sexual maturation in female rats after a very low dose of Bisphenol A through altered GABAergic neurotransmission and opposing effects of a high dose.
Franssen, Delphine ULg; GERARD, Arlette ULg; HENNUY, Benoit ULg et al

in Endocrinology (2016)

Rat sexual maturation is preceded by a reduction of the interpulse interval (IPI) of gonadotropinreleasing hormone (GnRH) neurosecretion. This work aims at studying disruption of that neuroendocrine event ... [more ▼]

Rat sexual maturation is preceded by a reduction of the interpulse interval (IPI) of gonadotropinreleasing hormone (GnRH) neurosecretion. This work aims at studying disruption of that neuroendocrine event in females after early exposure to a very low dose of Bisphenol A (BPA), a ubiquitous endocrine disrupting chemical. Female rats were exposed to vehicle or BPA 25 ng/kg.day, 25 g/kg.day, or 5 mg/kg.day from postnatal day (PND) 1 to 5 or 15. Exposure to 25 ng/kg.day of BPA for 5 or 15 days was followed by a delay in developmental reduction of GnRH IPI studied ex vivo on PND 20. After 15 days of exposure to that low dose of BPA, vaginal opening tended to be delayed. In contrast, exposure to BPA 5 mg/kg.day for 15 days resulted in a premature reduction inGnRHIPI and a trend toward early vaginal opening. RNAseq analysis on PND20 indicated that exposure to BPA resulted in opposing dose effectsonthemRNAexpression of hypothalamic genes involved inGABAA neurotransmission. The study of GnRH secretion in vitro in the presence of GABAA receptor agonist/antagonist confirmed an increased or a reduced GABAergic tone after in vivo exposure to the very low or the high dose of BPA, respectively. Overall, we show for the first time that neonatal exposure to BPA leads to opposing dose-dependent effects on the neuroendocrine control of puberty in the female rat. A very low and environmentally relevant dose of BPA delays neuroendocrine maturation related to puberty through increased inhibitory GABAergic neurotransmission. [less ▲]

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See detailInformation behaviour of French-speaking speech–language therapists in Belgium: results of a questionnaire survey
Durieux, Nancy ULg; Pasleau, Françoise ULg; Piazza, Aurélie ULg et al

in Health Information and Libraries Journal (2016), 33

BACKGROUND: Speech–language therapists (SLTs) are encouraged to implement evidence-based practice (EBP). Nevertheless, EBP use by practitioners can be questioned. OBJECTIVES: The objective of this study ... [more ▼]

BACKGROUND: Speech–language therapists (SLTs) are encouraged to implement evidence-based practice (EBP). Nevertheless, EBP use by practitioners can be questioned. OBJECTIVES: The objective of this study was to explore Belgian French-speaking SLTs’ information behaviour and their awareness of EBP. The collected data allow one to determine how far they have embraced this approach. METHODS: The two Belgian French-speaking SLT professional associations promoted an online questionnaire survey by email. Additionally, clinical supervisors of students were asked to participate. In March 2012, 2068 emails were sent. RESULTS: The participation rate was at least 20% (n = 415). The reported information needs mainly concerned treatment or diagnosis. Most of the time, to attempt to fulfil their information needs, SLTs relied on their own resources (personal experience and libraries) and on colleagues in the workplace. When they searched on the Internet, they preferred to use a general search engine rather than a specialised bibliographic database. Barriers to obtaining scientific information are highlighted. Only 12% of the respondents had already heard about EBP. CONCLUSION: This study provides the first overview of the information behaviour of SLTs working in the French community of Belgium. Several recommendations are suggested for SLTs and librarians. [less ▲]

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See detailQualités métrologiques de la version courte du Neurophysiology of Pain Questionnaire
Demoulin, Christophe ULg; Brasseur, P.; Roussel, N. et al

in Revue du Rhumatisme (2015, December), 82S

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See detailQue garder parmi les index de résistance à la fatigue?
Paulus, Julien ULg; Bosquet, Laurent; Gremeaux, Vincent et al

Conference (2015, November 20)

Objectif Les tests isocinétiques contribuent régulièrement à l'évaluation de la performance musculaire et en sont considérés comme un gold standard [1]. Les tests de fatigabilité peuvent s'avérer ... [more ▼]

Objectif Les tests isocinétiques contribuent régulièrement à l'évaluation de la performance musculaire et en sont considérés comme un gold standard [1]. Les tests de fatigabilité peuvent s'avérer complémentaires des épreuves courtes de force notamment pour évaluer un athlète sollicitant particulièrement la filière anaérobie lactique ou dans des contextes pathologiques spécifiques [2]. Bien que Bosquet et al. [3] aient démontré la reproductibilité d'un protocole de fatigabilité pour le genou, à notre connaissance, aucune étude, ayant pour objectif d'être exhaustive dans son analyse, n'a été menée sur la reproductibilité des paramètres mesurés (meilleure répétition, cumuls total et partiels) et index de fatigue (quotient des n dernières répétitions par les x premières, du cumul des répétitions par la meilleure,…). Ces index et paramètres mesurés sont néanmoins proposés directement par les dynamomètres, sans en connaître systématiquement la méthode de calcul, et/ou utilisés en clinique et dans la littérature pour caractériser la fatigabilité musculaire du genou [4]. Sont-ils cependant suffisamment reproductibles pour que leur utilisation soit scientifiquement validée? Matériel & méthode Dix-huit sujets, modérément actifs, ont réalisé trente extensions-flexions maximales du genou à trois occasions, avec sept à dix jours de repos entre chaque session. Le moment de force maximum (MFM) et le travail maximal (Wmax) de chaque répétition ont été enregistrés pour compiler onze paramètres mesurés et construire quarante-quatre index. La reproductibilité de chaque paramètre et index a été évaluée via leur ICC (2,1), SEM et MD respectifs. Résultats Les valeurs d'ICC des paramètres mesurés pour les extenseurs du genou sont quasi-systématiquement supérieures à 0.8 tandis que celles pour les fléchisseurs oscillent entre 0.7 et 0.8. Les valeurs d'ICC pour les "index de fatigue" construits sont inférieures à 0.7 et 0.5 respectivement pour les extenseurs et fléchisseurs. Aucune différence notable n'est observée entre la reproductibilité du MFM et celle du Wmax (que ce soit pour les extenseurs ou les fléchisseurs ou pour les paramètres mesurés et les "index de fatigue"). Discussion Au vu des valeurs obtenues sur notre population, il apparait qu'aucun index de fatigue calculé ne semble suffisamment reproductible pour une utilisation clinique ou scientifique! Seuls les paramètres mesurés tels que la meilleure répétition, le cumul total ou partiel présentent une reproductibilité qui peut être qualifiée de (très) haute voire excellente et sont donc utilisables en clinique ou en recherche pour caractériser la fatigabilité musculaire du genou. [less ▲]

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See detailHydroxyethyl Starch 130/0.4 and the Risk of Acute Kidney Injury After Cardiopulmonary Bypass: A Single-Center Retrospective Study.
LAGNY, Marc-Gilbert ULg; ROEDIGER, Laurence ULg; KOCH, Jean-Noël ULg et al

in Journal of Cardiothoracic and Vascular Anesthesia (2015)

Hydroxyethyl Starches (HES) have been shown to increase the risk of acute kidney injury (AKI) in intensive care unit patients suffering sepsis. Whether this risk also applies to patients undergoing ... [more ▼]

Hydroxyethyl Starches (HES) have been shown to increase the risk of acute kidney injury (AKI) in intensive care unit patients suffering sepsis. Whether this risk also applies to patients undergoing elective surgery remains unclear. We investigated whether HES is associated with acute kidney injury after on-pump cardiac surgery. Materials and Methods: Balanced HES 130/0.4 (Volulyte®, Fresenius Kabi AG, Bad Homburg, Germany) was used as a pump prime and for intraoperative fluid therapy until July 2013 and has been entirely replaced by a balanced crystalloid solution (Plasmalyte®, Baxter, Lessines, Belgium) from August 2013. Data from 697 adult patients undergoing cardiac surgery between April 2013 and June 2014 were reviewed. HES patients were propensity-matched on previously published risk factors for AKI after cardiac surgery to patients treated with crystalloids. Postoperative AKI was defined as the primary outcome and assessed using the Acute Kidney Injury Network classification. A conditional logistic regression was used to investigate the association between the use of HES and postoperative AKI. Secondary outcomes included renal function at postoperative day 7, 30-day mortality, lengths of ICU and hospital stays and the incidence of postoperative respiratory complications. Results and Discussion: One hundred and thirty HES patients were successfully matched with 130 crystalloids patients. HES was significantly associated with postoperative AKI (odds ratio=2.4; 95 % CI= 1.2-4.8; P=0.02). No significant association was found between HES and any of the secondary outcomes. Conclusion: This study suggests that using balanced HES 130/0.4 as a pump prime and for intraoperative fluid therapy in adult patients undergoing on-pump cardiac surgery is associated with a higher incidence of AKI during the early postoperative period. [less ▲]

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See detailLeucocytes and lipid particles filtration in suction blood during cardiopulmonary bypass: impact on kidney function evaluated with a monocentric prospective randomized study.
LAGNY, Marc-Gilbert ULg; KOCH, Jean-Noël ULg; BLAFFART, Francine ULg et al

Conference (2015, October 03)

OBJECTIVE: Cardiac surgery may be complicated by acute kidney injury (AKI). Cardiotomy suction during cardiopulmonary bypass (CPB) is deleterious. A few studies have demonstrated that shed mediastinal ... [more ▼]

OBJECTIVE: Cardiac surgery may be complicated by acute kidney injury (AKI). Cardiotomy suction during cardiopulmonary bypass (CPB) is deleterious. A few studies have demonstrated that shed mediastinal blood (SMB) suction during cardiopulmonary bypass (CPB) can increase inflammatory response and lipids emboli. These 2 factors contribute to the development of postoperative AKI. The RemoweLL (RemoweLeucoLipids, Eurosets™, Italy) filter is a recent designed cardiotomy with a multilayer filter for activated leucocytes filtration and a syphon for lipid particles sequestration. The SMB can be collected and filtered in this supplementary cardiotomy added to CPB circuit. The aim of this monocentric prospective study was to compare the specific RemoweLL cardiotomy filtration for suction blood during CPB and a conventional 40 µm filter (Admiral, Eurosets™, Italy). The primary goal was to evaluate the AKI within 48 hours after surgery using the Acute Kidney Injury Network classification (AKIN classification) but also measuring early specific biomarkers of AKI: serum Cystatine C and urinary neutrophil gelatinase-associated lipocalin (NGAL). METHODS: Sixty patients scheduled for elective cardiac surgery (aortic or mitral valvular combined or not with coronary bypass grafting) with a glomerular filtration rate (GFR) > 45mL/min. were randomly into 2 groups for SMB filtration: - Groupe 1 (n=30) with RemoweLL cardiotomy (Leucocytes and lipids filter); - Groupe 2 (n=30) with Admiral cardiotomy (conventional 40 µm filter). All components: venous reservoir, oxygenator and surface treatment were similar in both groups. [less ▲]

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See detailCivilian deaths from weapons used in the Syrian conflict
Guha-Sapir, Debarati; Rodriguez-Llanes, Jose; Hicks, Madelyn et al

in British Medical Journal (2015), 351

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See detailEffectiveness of High Intensity Radial Shock Wave Therapy in The Treatment of Chronic Plantar Fasciitis
Demoulin, Christophe ULg; Vanderthommen, Marc ULg; Fromm, Aurélien et al

in Jacobs Journal of Physical Rehabilitation Medicine (2015), 1(3), 0117

Detailed reference viewed: 55 (8 ULg)