References of "Delvenne, Catherine"
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See detailOrganising access to evidence-based medicine resources on the web
Delvenne, Catherine ULg; Pasleau, Françoise ULg

in Computer Methods & Programs in Biomedicine (2003), 71(1), 1-10

The continuing education is a challenge for health care professionals, considering the growing amount and variable quality of information in this field. In this context, we developed a method allowing ... [more ▼]

The continuing education is a challenge for health care professionals, considering the growing amount and variable quality of information in this field. In this context, we developed a method allowing clinicians to have a centralised access to the best current medical evidence supporting medical decision-making. Relevant data has been gathered according to the rules stated for Evidence-Based Medicine (EBM) and organised in a free-of-charge Web site, created by using common software applications. The general aim of our study was to encourage individual practice of EBM by providing tutorials as well as a selection of free access tools for searching medical information on the Web. In addition to the education part, we provided clinicians, through a Web interface, with up-to-date, accurate and quality data obtained from heterogeneous sources and presented in a full text format when available. The developed methodology has been applied to human prostate cancer. URL address: http://www.ebm.lib.ulg.ac.be/prostate/index.htm. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved. [less ▲]

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See detailDaily management of the transition to the future.
Goffinet, Nathalie ULg; Delvenne, Catherine ULg; Chalon, Patrice ULg et al

in Proceedings of the 8th European Conference of medical and Health Libraries, Köln, Septembre 16-21, 2002. (2002)

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See detailCréation d'un site Internet d'Evidence-Based Medicine.
Delvenne, Catherine ULg; Pasleau, Françoise ULg

in Médi-Sphère (2002), (67), 41-43

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See detailRecommandations pour la redaction de notices d'information pour les patients
Delvenne, Catherine ULg; Bonnet, Pierre ULg; Pasleau, Françoise ULg

in Revue Médicale de Liège (2001), 56(12), 840-5

With Evidence-Based Medicine, shared decision making is attracting considerable interest as a means by which patient preferences can be incorporated into clinical decisions. Patients cannot express ... [more ▼]

With Evidence-Based Medicine, shared decision making is attracting considerable interest as a means by which patient preferences can be incorporated into clinical decisions. Patients cannot express informed preferences unless they are given sufficient and appropriate information, including a detailed explanation concerning their condition, the different therapeutic options and the likely outcomes with and without treatment. A patient education leaflet is a potentially powerful tool for communicating information to patients, who will be able to participate in the process of decision making. The present article is a review of available guides for the writing of patient information materials. It also includes criteria for evaluating their quality. [less ▲]

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See detailLe Problem-Based Learning, description d'une pedagogie conduisant a la medecine factuelle
Chalon, Patrice ULg; Delvenne, Catherine ULg; Pasleau, Françoise ULg

in Revue Médicale de Liège (2000), 55(4), 233-8

Problem-Based Learning is an educational method which uses health care scenarios to provide a context for learning and to elaborate knowledge through discussion. Additional expectations are to stimulate ... [more ▼]

Problem-Based Learning is an educational method which uses health care scenarios to provide a context for learning and to elaborate knowledge through discussion. Additional expectations are to stimulate critical thinking and problem-solving skills, and to develop clinical reasoning taking into account the patient's psychosocial environment and preferences, the economic requirements as well as the best evidence from biomedical research. Appearing at the end of the 60's, it has been adopted by 10% of medical schools world-wide. PBL follows the same rules as Evidence-Based Medicine but is student-centered and provides the information-seeking skills necessary for self-directed life long learning. In this short article, we review the theoretical basis and process of PBL, emphasizing the teacher-student relationship and discussing the suggested advantages and disadvantages of this curriculum. Students in PBL programs make greater use of self-selected references and online searching. From this point of view, PBL strengthens the role of health libraries in medical education, and prepares the future physician for Evidence-Based Medicine. [less ▲]

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See detailSelection de ressources EBM sur l'Internet
Delvenne, Catherine ULg; Pasleau, Françoise ULg

in Revue Médicale de Liège (2000), 55(4), 220-5

To integrate Evidence-Based Medicine (EBM) into practice, the physician has access to a number of resources on the Internet. They belong to two distinct groups: tools intended for EBM learning and EBM ... [more ▼]

To integrate Evidence-Based Medicine (EBM) into practice, the physician has access to a number of resources on the Internet. They belong to two distinct groups: tools intended for EBM learning and EBM syntheses prepared by different international organizations. The present article presents the main EBM resources on the network and comments on them. These information are also available on the URL site: http:www.ebm.lib.ulg.ac.be/prostate/link_ebm .htm. [less ▲]

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See detailComment resoudre en pratique un probleme diagnostique ou therapeutique en suivant une demarche EBM?
Delvenne, Catherine ULg; Pasleau, Françoise ULg

in Revue Médicale de Liège (2000), 55(4), 226-32

Evidence-Based Medicine (EBM) can be defined as the use of best current evidence from clinical research in making decisions about the care of individual patients. It consists of a process of turning ... [more ▼]

Evidence-Based Medicine (EBM) can be defined as the use of best current evidence from clinical research in making decisions about the care of individual patients. It consists of a process of turning clinical problems into questions and then locating the best available evidence to answer them, critically appraising the evidence for its validity and usefulness, and applying the findings to clinical practice. The present article presents the EBM principles and their application to diagnostic and therapeutic questions. Further detailed information on Evidence-Based Medicine is presented at the URL address: http: inverted question markwww.ebm.lib.ulg.ac.be/prostate/ebm.+ ++htm. [less ▲]

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See detailAdenocarcinome pancreatique: role de l'anatomie pathologique
Delvenne, Philippe ULg; Delvenne, Catherine ULg; Quatresooz, Pascale ULg et al

in Revue Médicale de Liège (2000), 55(3), 135-40

Duct cell adenocarcinoma is by far the most frequent neoplasm of the pancreas, accounting for about 80% of malignant tumors. In this report, we describe the main diagnostic pitfalls of this cancer in ... [more ▼]

Duct cell adenocarcinoma is by far the most frequent neoplasm of the pancreas, accounting for about 80% of malignant tumors. In this report, we describe the main diagnostic pitfalls of this cancer in routine or frozen sections, as well as the help of immunohistology to make the differential diagnosis. We also discuss the potential interest of tumor markers for evaluating the prognosis of these tumors and provide information about the creation of a Web site (URL: http://www.ebm.lib.ulg.ac.be/index.htm) created to help clinicians exploit the laboratory results. [less ▲]

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See detailCreation of a Web site about Evidence-Based Medicine
Delvenne, Catherine ULg; Pasleau, Françoise ULg; Gielen, Jacques et al

in Proceedings of the 8th International Congress on Medical librarianship. (2000)

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See detailIntroduction aux bases de données : Medline et le vocabulaire MeSH.
Pasleau, Françoise ULg; Delvenne, Catherine ULg; Quinaux, N.

Learning material (2000)

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See detailEvaluation pronostique des tumeurs solides humaines par immunohistologie
Delvenne, Philippe ULg; Delvenne, Catherine ULg; Fridman, Viviana ULg et al

in Revue Médicale de Liège (1999), 54(8), 677-82

The aim of this project is to evaluate the interest of new tumor markers in the most frequent solid tumors (breast, colon, prostatic cancers, ...). For each of these tumors, potential prognostic markers ... [more ▼]

The aim of this project is to evaluate the interest of new tumor markers in the most frequent solid tumors (breast, colon, prostatic cancers, ...). For each of these tumors, potential prognostic markers have been selected according to the literature and an immunohistologic technique has been developed to analyse them. We will first discuss the role of pathology in oncology, then briefly describe the analyzed markers and finally give information about a Web site (URL: http:/(/)www.ebm. lib.ulg.ac.be/index.htm) created to help clinicians exploit the laboratory results. [less ▲]

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See detailGuidelines to Adapt the General Principles of the Non-statistical Meta-analysis Method to Specific Fields of Biomedical Research: the Example of Molecular Oncology.
Pasleau, Françoise ULg; Delvenne, Catherine ULg; Cielniaszek, Nadine

in Libraries without limits : changing needs – changing roles Proceedings of the 6th European Conference of medical and Health Libraries. (1999)

In most circumstances, considerable time lags before results from biomedical research are integrated in general medical practice are inevitable. Several economic, technical factors and educational ... [more ▼]

In most circumstances, considerable time lags before results from biomedical research are integrated in general medical practice are inevitable. Several economic, technical factors and educational orientation are responsible for this gap. Effective information management at the institutional level, could provide clinicians the means to adopt new perspectives. At present, the link between basic research and clinical application relies upon the motivation of individuals to develop new skills in literature retrieval and analysis and yet their occupational responsabilities inhibit this endeavour. Academic librarians, educated and trained in information and biomedical sciences, have a role in providing physicians with current and readily applicable knowledge from the critical analysis of the literature. The Faculty of Medicine Library is developing a research programme to design an updated and comprehensive picture of the diagnostic and prognostic biological markers in the field of human prostate cancer. The final product is envisioned as a database accessible on the web that will integrate bibliographic analyses and results from prospective and retrospective studies conducted at the University of Liège. As this product is designed to have a direct impact on clinical decision making and patient care, it should guarantee thoroughness, relevancy and objectivity and not become yet another narrative review of the literature. Over the last decade, there has been a movement towards using statistical meta-analyses to synthesize literature. This method has proven to be useful when similar strategies are used to produce similar quantitative outcomes that can be merged for statistical analysis.1 Even though studies in cancer research assess the same model, they are often too fragmented or heterogeneous in their design, methods and instrumentation. Approaches have been developed to conduct non-statistical meta-analysis of such publications.2 Quantitative and qualitative meta-analyses are based on common principles which are largely discussed in the literature. They are related to model development, literature coding, rating references for quality and annotating and synthesizing high quality references. In practice, these basic principles require translation into actual instructions adapted to every domain of biomedical research. Variable definition is a very critical step that governs the quality of subsequent analyses. Specific examples provided illustrate the guidelines acquired from our experience. Il s'écoule souvent un intervalle de temps fort long avant que les nouveaux concepts issus de la recherche biomédicale soient intégrés dans la pratique médicale courante. Les raisons de cette situation sont autant d'ordre économique et technique que culturel. Actuellement, les liens entre la recherche fondamentale et la médecine clinique ne peuvent exister que sur base d'initiatives individuelles et les médecins concernés doivent investir une partie de leur temps dans l'apprentissage des techniques de recherche et d'analyse de la littérature. Une gestion professionnelle de l'information au niveau d'une institution telle qu'un hôpital universitaire devrait par contre inciter davantage de cliniciens à utiliser les ressources de la littérature issue de la recherche biomédicale. C'est pourquoi la Bibliothèque de la Faculté de Médecine de l'Université de Liège propose, à titre expérimental, de créer un prototype de site web consacré à l'étude des marqueurs pronostiques et diagnostiques du cancer de la prostate. Des scientifiques, spécialisés en sciences biomédicales et formés aux techniques de gestion documentaire, fourniront à l'intention des médecins spécialistes et/ou généralistes, voire des patients eux-mêmes, une analyse critique de la littérature en relation directe avec les activités cliniques de l'institution. Notre objectif étant de fournir aux médecins des informations susceptibles d'être utilisées comme bases de décision clinique, notre responsabilité se trouve engagée vis à vis des patients. Nous devrons donc définir une stratégie qui garantisse à la fois l'exhaustivité et la pertinence de l'information traitée et l'objectivité des analyses présentées. Sur base des principes de la méta-analyse,1,2 nous avons conçu un protocole en cinq étapes comprenant: la définition à priori des objectifs, la recherche non biaisée d'information, la définition de critères de sélection des études, l'extraction et la synthèse des données. La difficulté consistera à traduire ces principes en une série de consignes pratiques et techniques et d'en dégager des lignes de conduite générales qui permettront d'étendre cette approche à n'importe quel domaine de la médecine. 1. D'Agostino RB, Weintraub M. Meta-analysis: a method for synthesizing research. Clin Pharmacol Ther 1995;58:605-616 2. Bland CJ, Meurer LN, Maldonado G. A systematic approach to conducting a non-statistical meta-analysis of research literature. Acad Med 1995;70:642-653 [less ▲]

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See detailBibliothèques et Informatique médicale.
Delvenne, Catherine ULg; Pasleau, Françoise ULg

in Newsletter to European Health Librarians (1999), (54), 677-382

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See detailGuidelines to Adapt the General Principles of the Non-statistical Meta-analysis Method to Specific Fields of Biomedical Research: the Example of Molecular Oncology.
Pasleau, Françoise ULg; Delvenne, Catherine ULg; Cielnaszek, Nadine

Conference (1998, June 26)

In most circumstances, considerable time lags before results from biomedical research are integrated in general medical practice are inevitable. Several economic, technical factors and educational ... [more ▼]

In most circumstances, considerable time lags before results from biomedical research are integrated in general medical practice are inevitable. Several economic, technical factors and educational orientation are responsible for this gap. Effective information management at the institutional level, could provide clinicians the means to adopt new perspectives. At present, the link between basic research and clinical application relies upon the motivation of individuals to develop new skills in literature retrieval and analysis and yet their occupational responsabilities inhibit this endeavour. Academic librarians, educated and trained in information and biomedical sciences, have a role in providing physicians with current and readily applicable knowledge from the critical analysis of the literature. The Faculty of Medicine Library is developing a research programme to design an updated and comprehensive picture of the diagnostic and prognostic biological markers in the field of human prostate cancer. The final product is envisioned as a database accessible on the web that will integrate bibliographic analyses and results from prospective and retrospective studies conducted at the University of Liège. As this product is designed to have a direct impact on clinical decision making and patient care, it should guarantee thoroughness, relevancy and objectivity and not become yet another narrative review of the literature. Over the last decade, there has been a movement towards using statistical meta-analyses to synthesize literature. This method has proven to be useful when similar strategies are used to produce similar quantitative outcomes that can be merged for statistical analysis.1 Even though studies in cancer research assess the same model, they are often too fragmented or heterogeneous in their design, methods and instrumentation. Approaches have been developed to conduct non-statistical meta-analysis of such publications.2 Quantitative and qualitative meta-analyses are based on common principles which are largely discussed in the literature. They are related to model development, literature coding, rating references for quality and annotating and synthesizing high quality references. In practice, these basic principles require translation into actual instructions adapted to every domain of biomedical research. Variable definition is a very critical step that governs the quality of subsequent analyses. Specific examples provided illustrate the guidelines acquired from our experience. 1. D'Agostino RB, Weintraub M. Meta-analysis: a method for synthesizing research. Clin Pharmacol Ther 1995;58:605-616 2. Bland CJ, Meurer LN, Maldonado G. A systematic approach to conducting a non-statistical meta-analysis of research literature. Acad Med 1995;70:642-653 [less ▲]

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See detailFacteurs pronostiques du cancer de la prostate : création d’un site Internet basé sur des évidences.
Delvenne, Catherine ULg; Cielniaszek, N.; Gielen, Jacques et al

in Informatique et Santé, Santé et Réseaux Informatiques : Comptes-rendus des journées Francophones d’Informatique Médicale, Liège, Avril 1998. (1998)

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See detailDetection of Human Papillomaviruses in Paraffin-Embedded Biopsies of Cervical Intraepithelial Lesions: Analysis by Immunohistochemistry, in Situ Hybridization, and the Polymerase Chain Reaction
Delvenne, Philippe ULg; Fontaine, Marie-Anne; Delvenne, Catherine ULg et al

in Modern Pathology : An Official Journal of the United States & Canadian Academy of Pathology, Inc (1994), 7(1), 113-119

One hundred and forty biopsies with an initial diagnosis of cervical intraepithelial lesion (CIL) were tested for the presence of human papillomavirus (HPV) by immunohistochemistry and in situ ... [more ▼]

One hundred and forty biopsies with an initial diagnosis of cervical intraepithelial lesion (CIL) were tested for the presence of human papillomavirus (HPV) by immunohistochemistry and in situ hybridization using commercial biotinylated probes (Vira-Type in situ assay; Digene Diagnostics, Silver Spring, MD) or probes labeled with digoxigenin by the random primer technique. Immunohistochemistry was more inferior to the in situ hybridization method, with a detection rate of 14% (20/140) compared to 61% (86/140) for the in situ assay with the digoxigenin-labeled probes. Biotinylated probes proved to be slightly less sensitive than digoxigenin-labeled probes, with a detection rate of 53% (74/140). Although less sensitive in our series taken as a whole, immunohistochemistry was positive in a few cases of CILs negative by in situ hybridization, so that the association of these techniques gave the highest detection rate (66%; 92/140). The CILs that remained negative with these methods (34%; 48/140) were investigated by the polymerase chain reaction (PCR) using consensus primers to determine definitively the presence of HPV in these lesions and were reviewed histologically to assess the diagnosis of CILs. The PCR method increased the detection rate of HPV in our series to 76% (107/140). The diagnosis of CILs was confirmed for all the biopsy specimens positive by PCR (15/15; 100%) and for all the HPV negative tissues with histological features of a high-grade lesions (7/7; 100%).(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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