References of "Del Fiore, G"
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See detailSimple device for the radiosynthesis of [carbonyl-11C]amides, esters and ketones using carbon-11 monoxide.
Brichard, L.; Del Fiore, G.; Lemaire, Christian ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (2003), 46

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See detailBrain activation during somatosensory and auditory stimulation in acute vegetative state of anoxic origin
Laureys, Steven ULg; Faymonville, Marie ULg; Del Fiore, G. et al

in Physiological imaging of the brain with PET (2000)

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See detailPreoperative evaluation of 54 gliomas by PET with fluorine-18-fluorodeoxyglucose and/or carbon-11-methionine.
Kaschten, Bruno ULg; Stevenaert, Achille ULg; Sadzot, Bernard ULg et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1998), 39(5), 778-85

This study evaluates the usefulness of PET for the preoperative evaluation of brain gliomas and methods of quantification of PET results. METHODS: Fifty-four patients with brain gliomas were studied by ... [more ▼]

This study evaluates the usefulness of PET for the preoperative evaluation of brain gliomas and methods of quantification of PET results. METHODS: Fifty-four patients with brain gliomas were studied by PET with 18F-fluorodeoxyglucose (FDG) (n = 45) and/or 11C-methionine (MET) (n = 41) before any treatment. Results of visual analysis, calculation of glucose consumption and five tumor-to-normal brain ratios for both tracers were correlated with two histologic grading systems and with follow-up. RESULTS: Visual analysis (for FDG) and tumor-to-mean cortical uptake (T/MCU) ratio proved to be the best tools for the evaluation of PET results. Methionine was proven to be better than FDG at delineating low-grade gliomas. Tumor-to-mean cortical uptake ratios for FDG and MET were clearly correlated (r = 0.78), leading to the equation T/MCU(FDG) = 0.4 x T/MCU(MET). We showed a good correlation between FDG PET and histologic grading. MET uptake could not differentiate between low-grade and anaplastic astrocytomas but was significantly increased in glioblastomas. Low-grade oligodendrogliomas exhibited high uptake of FDG and MET, probably depending more on oligodendroglial cellular differentiation than on proliferative potential. Uptake was decreased in anaplastic oligodendrogliomas, probably due to dedifferentiation. Care must be taken with peculiar histologic subgroups, i.e., juvenile pilocytic astrocytomas and oligodendrogliomas, because of a discrepancy between high PET metabolism and low proliferative potential (good prognosis). Both tracers proved useful for the prediction of survival prognosis. Methionine proved slightly superior to FDG for predicting the histologic grade and prognosis of gliomas, despite the impossibility of differentiation between Grades II and III astrocytomas with MET. This superiority of MET could be explained by patient sampling (low number of Grade III gliomas submitted to examination with both tracers). The combination of both tracers improved the overall results compared to each tracer alone. CONCLUSION: Both tracers are useful for the prediction of the histologic grade and prognosis. The apparent superiority of MET over FDG could be due to the small number of Grade III gliomas studied with both tracers. [less ▲]

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See detailS-, N- and O-[11C]methylations of a Nor precursor adsorbed on Al2O3/KF.
Schmitz, F.; Plenevaux, Alain ULg; Del Fiore, G. et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1995), 37

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See detail[1-11C]Bromoethane: an alternative to the use of [1-11C]iodoethane.
Schmitz, F.; Del Fiore, G.; Plenevaux, Alain ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1995), 37

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See detailFast quality control of short-lived radiopharmaceutical compounds with a photodiode array detector.
Plenevaux, Alain ULg; Lemaire, Christian ULg; Aerts, Joël ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1995), 37

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See detailFast routine production of L-[11C-methyl]methionine with Al2O3/KF in a disposable unit.
Del Fiore, G.; Schmitz, F.; Plenevaux, Alain ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1995), 37

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See detailSep Pak as alternative to rotary evaporators for radiopharmaceutical formulations.
Lemaire, Christian ULg; Plenevaux, Alain ULg; Del Fiore, G. et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1995), 37

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See detailEnantioselective syntheses of n.c.a. L-(a-methyl)-[b-11C]-4-chlorophenylalanine and L-(a-[11C]methyl-tryptophan.
Plenevaux, Alain ULg; Al-Darwich, M. J.; Lemaire, Christian ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1994), 35

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See detail11C-alkylation on Al2O3/MF: a useful method for rapid labelling.
Schmitz, F.; Plenevaux, Alain ULg; Del Fiore, G. et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1994), 35

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See detailAl2O3/KF in radiochemistry: fast preparation of L-[11C-methyl]methionine without HPLC.
Schmitz, F.; Plenevaux, Alain ULg; Del Fiore, G. et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1994), 35

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See detailAsymmetric synthesis of n.c.a. L-[2-11C]-4-chlorophenylalanine.
Plenevaux, Alain ULg; Al-Darwich, M. J.; Lemaire, Christian ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1993), 32

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See detailThrombolysis in anterior myocardial infarction: effect on regional viability studied with positon emission tomography
de landsheere, C. M.; Raets, D.; Pierard, Luc ULg et al

in Circulation (1987), 76(suppl.IV), 5

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