References of "Defourny, Jean"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailStructure and development of cochlear afferent innervation in mammals.
Defourny, Jean ULg; Lallemend, Francois; Malgrange, Brigitte ULg

in American Journal of Physiology - Cell Physiology (2011), 301(4), 750-61

In mammals, sensorineural deafness results from damage to the auditory receptors of the inner ear, the nerve pathways to the brain or the cortical area that receives sound information. In this review, we ... [more ▼]

In mammals, sensorineural deafness results from damage to the auditory receptors of the inner ear, the nerve pathways to the brain or the cortical area that receives sound information. In this review, we first focused on the cellular and molecular events taking part to spiral ganglion axon growth, extension to the organ of Corti, and refinement. In the second half, we considered the functional maturation of synaptic contacts between sensory hair cells and their afferent projections. A better understanding of all these processes could open insights into novel therapeutic strategies aimed to re-establish primary connections from sound transducers to the ascending auditory nerve pathways. [less ▲]

Detailed reference viewed: 28 (11 ULg)