References of "DIVE, Dominique"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailMultimodal evoked potentials for functional quantification and prognosis in multiple sclerosis
GIFFROY, Xavier ULg; MAES, Nathalie ULg; Albert, Adelin ULg et al

in BMC Neurology (2016)

Functional biomarkers able to identify multiple sclerosis (MS) patients at high risk of fast disability progression are lacking. The aim of this study was to evaluate the ability of multimodal (upper and ... [more ▼]

Functional biomarkers able to identify multiple sclerosis (MS) patients at high risk of fast disability progression are lacking. The aim of this study was to evaluate the ability of multimodal (upper and lower limbs motor, visual, lower limbs somatosensory) evoked potentials (EP) to monitor disease course and identify patients exposed to unfavourable evolution. One hundred MS patients were assessed with visual, somatosensory and motor EP and rated on the Expanded Disability Status Scale (EDSS) at baseline (T0) and about 6 years later (T1). The Spearman correlation (rS) was used to evaluate the relationship between conventional EP scores and clinical findings. Multiple (logistic) regression analysis estimated the predictive value of baseline electrophysiological data for three clinical outcomes: EDSS, annual EDSS progression, and the risk of EDSS worsening. In contrast to longitudinal correlations, cross-sectional correlations between the different EP scores and EDSS were all significant (0.33 ≤ rS < 0.67, p < 0.001). Baseline global EP score and EDSS were highly significant predictors (p < 0.0001) of EDSS progression 6 years later. The aseline global EP score was found to be an independent predictor of the EDSS annual progression rate (p < 0.001), and of the risk of disability progression over time (p < 0.005). Based on a ROC curve determination, we defined a Global EP Score cut off point (17/30) to identify patients at high risk of disability progression illustrated by a positive predictive value of 70 %. This study provides a proof of the concept that electrophysiology could be added to MRI and used as another complementary prognostic tool in MS patients. [less ▲]

Detailed reference viewed: 46 (11 ULg)
Full Text
Peer Reviewed
See detailDo evoked potentials contribute to the functional follow-up and clinical prognosis of multiple sclerosis?
GIFFROY, Xavier ULg; MAES, Nathalie ULg; Albert, Adelin ULg et al

in Acta Neurologica Belgica (2016)

The clinical variability and complexity of multiple sclerosis (MS) challenges the individual clinical course prognostication. This study aimed to find out whether multimodal evoked potentials (EP ... [more ▼]

The clinical variability and complexity of multiple sclerosis (MS) challenges the individual clinical course prognostication. This study aimed to find out whether multimodal evoked potentials (EP) correlate with the motor components of multiple sclerosis functional composite (MSFCm) and predict clinically relevant motor functional deterioration. One hundred MS patients were assessed at baseline (T0) and about 7.5 years later (T1), with visual, somatosensory and motor EP and rated on the Expanded Disability Status Scale (EDSS) and the MSFCm, including the 9 Hole Peg Test and the Timed 25 Foot Walk (T25FW). The Spearman correlation coefficient (rS) was used to evaluate the cross-sectional and longitudinal relationship between EP Z scores and clinical findings. The predictive value of baseline electrophysiological data for clinical worsening (EDSS, 9-HPT, T25FW, MSFCm) during follow-up was assessed by logistic regression analysis. Unlike longitudinal correlations, cross-sectional correlations between EP Z scores and clinical outcomes were all significant and ranged between 0.22 and 0.67 (p\0.05). The global EP Z score was systematically predictive of EDSS and MSFCm worsening over time (all p\0.05). EP latency was a better predictor than amplitude, although weaker than latency and amplitude aggregation in the global EP Z score. The study demonstrates that EP numerical scores can be used for motor function monitoring and outcome prediction in patients with MS. [less ▲]

Detailed reference viewed: 40 (5 ULg)
Full Text
See detailPlace de l'exploration neurophysiologique dans la SEP
DIVE, Dominique ULg; GIFFROY, Xavier ULg; WANG, François-Charles ULg

Conference (2014, October 11)

Detailed reference viewed: 35 (6 ULg)
Full Text
Peer Reviewed
See detailCe cavernome cérébral est-il la cause d'un syndrome parkinsonien ?
Benmouna, Karim ULg; DIVE, Dominique ULg; WANG, François-Charles ULg et al

in Revue Médicale de Liège (2013), 68(12), 613-616

We report the case of a patient presenting with an akineto-rigid syndrome of the left hemibody whose etiological exploration by magnetic resonance imaging showed the presence of a cavernoma located in the ... [more ▼]

We report the case of a patient presenting with an akineto-rigid syndrome of the left hemibody whose etiological exploration by magnetic resonance imaging showed the presence of a cavernoma located in the right lenticular region. The interest of this situation lies in establishing whether pathophysiological link may exist between such symptoms and the lesion. [less ▲]

Detailed reference viewed: 214 (40 ULg)
Full Text
Peer Reviewed
See detailPartial trisomy 4q associated with young-onset dopa-responsive parkinsonism.
Garraux, Gaëtan ULg; CABERG, Jean-Hubert ULg; Vanbellinghen, Jean-Francois et al

in Archives of Neurology (2012), 69(3), 398-400

OBJECTIVE: To describe a patient who developed a young-onset, dopa-responsive parkinsonism linked to a de novo heterozygous interstitial duplication 4q. DESIGN: Case report. SETTING: Movement Disorder ... [more ▼]

OBJECTIVE: To describe a patient who developed a young-onset, dopa-responsive parkinsonism linked to a de novo heterozygous interstitial duplication 4q. DESIGN: Case report. SETTING: Movement Disorder Outpatient Clinic at the University Hospital Centre, Liege, Belgium. Patient A 31-year-old woman. MAIN OUTCOME MEASURES: Clinical, neuroimaging, and genetic data. RESULTS: The duplicated region contains 150 known genes, including the alpha-synuclein (SNCA) gene locus. Motor and 6-[(18)F]fluoro-L-dopa positron emission tomography features are similar to those previously reported in heterozygote SNCA duplication carriers. Altered expression of other genes contained in the duplicated region may contribute to clinical features that are uncommon in the phenotypic spectrum of SNCA multiplications such as delayed developmental psychomotor milestones during infancy and musculoskeletal abnormalities. CONCLUSION: This case report provides new insights on the genetic basis of parkinsonism. [less ▲]

Detailed reference viewed: 43 (11 ULg)
Full Text
Peer Reviewed
See detailLa maladie d'Hirayama
WANG, François-Charles ULg; GÖBELS, Catherine ULg; TOMASELLA, Marco ULg et al

in Correspondances en Nerf & Muscle (2011), XV(7), 246-252

La MH reste une maladie rare et sa physiopathologie, toujours incertaine, rend le choix thérapeutique quelque peu hasardeux. Le port du collier cervical semble indiqué en phase évolutive dans les formes ... [more ▼]

La MH reste une maladie rare et sa physiopathologie, toujours incertaine, rend le choix thérapeutique quelque peu hasardeux. Le port du collier cervical semble indiqué en phase évolutive dans les formes les plus typiques. Lorsque se surajoute une compression visible de la moelle cervicale en position neutre, une image cavitaire intra-médullaire ou une atteinte débordant les cornes antérieures, un geste chirurgical devra être discuté. [less ▲]

Detailed reference viewed: 180 (20 ULg)
Full Text
Peer Reviewed
See detailMétastase septique dorsale secondaire d’un abcès rétropharyngé responsable d’une tétraparésie
Kaux, Jean-François ULg; LENELLE, Jacques ULg; FRIPPIAT, Frédéric ULg et al

in Revue Neurologique (2011), 167(8-9), 638-640

Introduction: Peri-tonsillar abscess remains one of the most frequent serous complications of oropharyngeal or dental infections. It can evolve to parapharyngeal and/or retropharyngeal spaces. It can be ... [more ▼]

Introduction: Peri-tonsillar abscess remains one of the most frequent serous complications of oropharyngeal or dental infections. It can evolve to parapharyngeal and/or retropharyngeal spaces. It can be life-threatning and, more rarely, neurological complications are described. Observations: We report the case of a 56 year old woman who developed within few days a progressive tetraparesia due to cervical medullary compression. This compression was consecutive to an epidurite which was a complication of a retropharyngeal abscess. The only surgical act was a cervicotomy to drain the abscess and identify the pathological germ. A targeted antibiotherapy was quickly begun. The recovery was obtained rather quickly and the neurological evolution was good. After one year, the cervical spine presents a post-infectious deformation without sign of root or spinal-cord compression. Conclusion: A cervical tetraparesia induced by spondylodiscitis and epiduritis following a retropharyngeal abscess with Staphylococcus aureus is a rare complication. Adequate diagnosis, as fast as possible, is mandatory in order to carry out an adapted antibiotherapy in the hopes of a complete recovery. The place of surgery on the spine remains to be specified. [less ▲]

Detailed reference viewed: 396 (18 ULg)
Full Text
Peer Reviewed
See detailLatence du potentiel global d’action musculaire du muscle 1er interosseux dorsal de la main
Kaux, Jean-François ULg; Dive, Dominique ULg; Wang, François-Charles ULg

in Lettre du Neurologue (La) : le Courrier du Spécialiste (2011), XV(1), 21-23

Detailed reference viewed: 61 (7 ULg)
Full Text
Peer Reviewed
See detailRéponses « prémotrices » du muscle premier interosseux dorsal de la main
Kaux, Jean-François ULg; Dive, Dominique ULg; Wang, François-Charles ULg

in XVIIèmes Journées Francophones d'Electroneuromyographie (2010, June 11)

Introduction – Lors de l’enregistrement du potentiel global d’action musculaire (PGAM) au niveau du muscle premier interosseux dorsal de la main (PID) après stimulation du nerf ulnaire au poignet, il est ... [more ▼]

Introduction – Lors de l’enregistrement du potentiel global d’action musculaire (PGAM) au niveau du muscle premier interosseux dorsal de la main (PID) après stimulation du nerf ulnaire au poignet, il est habituel d’observer un pic positif initial (pour une amplification d’environ 1 mV par division). Objectif – Déterminer l’origine de cette déflection positive précédant le PAGM du PID lors de la stimulation du nerf ulnaire au poignet. S’agit-il d’une réponse motrice générée au voisinage de l’électrode de détection active (champ proche) ? La positivité signifiant que les plaques motrices, où est générée cette réponse, ne sont pas exactement sous l’électrode active. S’agit-il, au contraire, de la captation d’une activité générée nettement à distance du système de détection (champ lointain) ? La positivité étant alors liée à l’orientation d’un dipôle électrique par rapport au système de détection. Sujets et méthodes - Dix patients successifs, indemnes d’atteinte du nerf ulnaire, sont étudiés. Une électrode active (G1) est placée sur le PID, au sommet de la saillie musculaire provoquée par le rapprochement actif du pouce et de l’index. L’électrode de référence (G2) est placée successivement sur le pouce, l’index, l’auriculaire, l’os trapèze au poignet et sur le membre controlatéral. Une stimulation électrique percutanée est appliquée au nerf ulnaire au poignet. Le muscle abducteur du Vème doigt (AB5) est également étudié (G1 au milieu de l’éminence hypothénar et G2 sur l’auriculaire). Résultats – Le pic positif précédant le PAGM du PID est en moyenne plus ample lorsque l’électrode de référence est placée sur l’index. Le PAGM du PID débute systématiquement par une déflection négative lorsque l’électrode de référence est placée sur l’os trapèze au poignet ou sur le membre controlatéral. L’absence de positivité initiale est associée à un raccourcissement de la latence distale motrice. Lorsque le gain des réponses motrices du PID et de l’AB5 est fixé à 0,1 ou 0,2 mV/division, quel que soit le muscle étudié et quel que soit le montage G1/G2 utilisé, toutes les déflections initiales (positives ou négatives) présentent une latence identique ou presque. Discussion – La déflection positive initiale qui précède le PAGM du PID, lorsque G2 est distale par rapport à la cathode, reflète l’activité générée au niveau des autres muscles innervés par le nerf ulnaire et notamment l’AB5. L’absence de cette positivité, lorsque G2 est proximale à la cathode ou sur le membre controlatéral, est liée à une inversion de polarité de la déflection initiale. Il en résulte, une réduction artificielle de la latence distale motrice. Ce type de référence doit donc être évité dans nos examens de routine. Conclusion – Ce travail souligne d’une part, l’importance de G2 dans l’enregistrement d’un PAGM et d’autre part, que les enregistrements de surface peuvent être influencés par la contraction de muscles situés à distance du couple G1/G2, même si un seul nerf est activé par la stimulation électrique percutanée. [less ▲]

Detailed reference viewed: 50 (4 ULg)
Full Text
Peer Reviewed
See detailMotor neuron disorders : novel electrophysiologic approach (MUFDEC protocol)
WANG, François-Charles ULg; Le Forestier, Nadine; WANG, Pascale ULg et al

in Clinical Neurophysiology (2009), Suppl(Vol 60), 143-152

Detailed reference viewed: 21 (5 ULg)
Full Text
Peer Reviewed
See detailDe novo interstitial duplication 4q associated with sporadic young-onset dopa-responsive parkinsonism
Garraux, Gaëtan ULg; VANBELLINGHEN, Jean-François ULg; JAMAR, Mauricette ULg et al

in Movement Disorders : Official Journal of the Movement Disorder Society (2009), 24(Suppl. 1), 138-139

Detailed reference viewed: 10 (3 ULg)
Full Text
See detailExploration musculaire isocinétique dans la sclérose en plaques : épreuves de force et de fatigabilité
Maquet, Didier ULg; Dive, Dominique ULg; Hengen, Christine ULg et al

in Abstract book de la 6ème Journée Belge d’Isocinétisme du GIBL (2008, March)

Detailed reference viewed: 175 (15 ULg)
Peer Reviewed
See detailIsokinetic strength and fatigability in patients with multiple sclerosis. The relationship between gait speed and isokinetic parameters
Maquet, Didier ULg; Dive, Dominique ULg; Entem, Arnaud et al

in Isokinetics & Exercise Science (2007), 15

Introduction Multiple sclerosis (MS) is a chronic disease characterized by inflammation and demyelisation of the central nervous system. Decline of muscular performances, fatigue, weakness and spasticity ... [more ▼]

Introduction Multiple sclerosis (MS) is a chronic disease characterized by inflammation and demyelisation of the central nervous system. Decline of muscular performances, fatigue, weakness and spasticity are the most common and disabling symptoms characterizing this neurological disease. Undoubtedly, objective assessments of muscle function would be relevant to deliver the most appropriate treatment and to appraise possible training effects resulting from rehabilitation. The purposes of this study were to assess muscle strength and fatigue of knee flexors and extensors in patients with multiple sclerosis by means of an isokinetic dynamometer. Relations between isokinetic results and gait speed were also investigated. Methods Eight patients (49 +/- 7 years old) suffering from multiple sclerosis (with unaided gait) were included in this study. Bilateral knee flexor and extensor performances were assessed using a Cybex Norm dynamometer. Maximal isokinetic strength was measured at 60°/s (3 repetitions) and 180°/s (5 repetitions). Thereafter, patients performed a fatigue protocol consisting in 30 successive maximal-intensity knee flexions and extensions at 180°/s angular velocity. Fatigue was analysed using the cumulative work parameter (corresponding to the sum of work developed through the 30 movements) and a fatigue index (ratio between work developed during 3 last contractions and 3 first contractions). Gait speeds corresponded to the time necessary to subject for walking at maximal speed on a 7.62 m and 100 m long walkway. Results Isokinetic parameters (strength and fatigue) appeared to be decreased in MS patients comparatively to normative data [1]. Knee flexors/extensors ratio was reduced for some patients, yet MS subjects displayed no significant bilateral asymmetry, suggesting a bilateral weakness process. Significant negative correlations (- 0.76 < r < - 0.95, p < 0.05) between gait speeds (measured through a 7.62 m and 100 m long walkway) and hamstring isokinetic parameters (peak torque and cumulative work) were observed. In contrast, we did not find any correlation between gait speed and quadriceps isokinetic performances, except for the correlation between gait speed on 100 m long walkway and fatigue index (0.78 < r < 0.89, p < 0.05). Discussion and conclusion Objective evaluation of muscle performance deficiencies in patients with MS appears essential for designing a successful rehabilitation program. However, no consensus has been established with regard to the most relevant isokinetic protocol modalities for assessing patients suffering form central nervous system lesions. Our preliminary results underlined that gait speed was negatively correlated to hamstring isokinetic parameters (strength and cumulative work). Interestingly, no patient included in our study reported increased symptoms such as spasticity during or after the test, indicating that MS patients are able to perform strength and fatigue isokinetic assessments. References [1] Maquet D, Croisier JL, Renard C, Crielaard JM. Muscle performance in patients with fibromyalgia, Joint Bone Spine 69 :293-9, 2002. [less ▲]

Detailed reference viewed: 184 (17 ULg)
Full Text
See detailL'image du mois. Un cas de leucoencephalopathie rapidement progressive sur angiopathie amyloide
Wauters, Odile ULg; Scholtes, Félix ULg; Dive, Dominique ULg et al

in Revue Médicale de Liège (2006), 61(1), 3-4

Detailed reference viewed: 169 (14 ULg)
Full Text
Peer Reviewed
See detailTrigeminal nociceptive evoked potentials (TNEP) in migraine
Magis, Delphine ULg; Allena, Marta; De Pasqua, Victor ULg et al

in Cephalalgia : An International Journal of Headache (2005, October), 25(10), 875

Detailed reference viewed: 36 (7 ULg)
Full Text
Peer Reviewed
See detailObservation n°5 (cas particulier de Parsonage & Turner)
Wang, François ULg; Kaux, Jean-François ULg; Dive, Dominique ULg

in Correspondances en Nerf & Muscle (2005, June), (Numéro spécial), 20-23

Detailed reference viewed: 231 (89 ULg)
Full Text
Peer Reviewed
See detailNeuropathie périphérique diabétique
DIVE, Dominique ULg; LIEVENS, Isabelle ULg; Moonen, Gustave ULg et al

in Revue Médicale de Liège (2005)

Detailed reference viewed: 22 (3 ULg)
Peer Reviewed
See detailCas clinique
WANG, François-Charles ULg; DIVE, Dominique ULg

Conference (2001, January 27)

Detailed reference viewed: 9 (1 ULg)