References of "Coghe, J"
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See detailConcepts in the prevention of bovine respiratory disease.
Makoschey, B.; Lekeux, Pierre ULg; Lacroux, C. et al

in Berliner und Munchener Tierarztliche Wochenschrift (2008), 121(11-12), 446-449

The bovine respiratory disease (BRD) complex requires further research both, to fully understand the disease from the different perspectives as well as to develop new tools and strategies for vaccination ... [more ▼]

The bovine respiratory disease (BRD) complex requires further research both, to fully understand the disease from the different perspectives as well as to develop new tools and strategies for vaccination and treatment was the conclusion at a recent BRD symposium in Rome, Italy. A group of scientist across Europe followed the invitation of Prof. E. Thiry (University of Liège, Belgium) to convene for a 2 days workshop type symposium sponsored by Intervet/Schering-Plough Animal Health (Fig. 1 – group picture) [less ▲]

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See detailAffections respiratoires bovines : évolution des lésions pulmonaires et rapidité d’intervention
Lekeux, Pierre ULg; Coghe, J.

in Proceedings: Congrès de la Société Française de Buiatrie (2004)

Respiratory disease is the principal cause of loss of young cattle worldwide. The syndrome arises from a number of factors, including those involving the animal, e.g., age, general condition and immune ... [more ▼]

Respiratory disease is the principal cause of loss of young cattle worldwide. The syndrome arises from a number of factors, including those involving the animal, e.g., age, general condition and immune status; its environment, e.g., changes in food, temperature and humidity that lead to stress; and the presence of infectious agents, e.g., bacteria, viruses and mycoplasmas. The syndrome, in a method proposed by the author, can be classified into four grades: Grade 1, subclinical disease; Grade 2, compensated clinical disease; Grade 3, noncompensated clinical disease; and Grade 4, irreversible clinical disease. The increase in frequency and economic impact of bovine respiratory disease complex can be correlated with the escalating industrialisation of cattle production. In intensive operations, commingling of animals from multiple sources, exposure to many organisms, stress and management practices are all factors that can lead to disease. The predisposition of cattle, especially beef calves, to respiratory problems is related to their lack of functional pulmonary hardiness. Selection of breeds that demonstrate adequate pulmonary function and sufficient ventilatory reserve may help in the control of the bovine respiratory disease complex, but this approach is difficult to implement and slow to produce results. Prophylactic measures, including vaccination programmes and modifying management practices to reduce stress, also have a place in preventing the bovine respiratory disease complex. Unfortunately, these measures are not always easy to put into operation and cannot completely eradicate the problem. Therapeutic strategies to minimise the economic impact of the syndrome include use of early antibacterial therapy, modulation of the pulmonary inflammatory reaction and correction of mechanical disorders [less ▲]

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See detailAcute phase proteins assessment for an early selection of treatments in growing calves suffering from bronchopneumonia under field conditions
Humblet, Marie-France ULg; Coghe, J.; Lekeux, Pierre ULg et al

in Research in Veterinary Science (2004), 77(1), 41-47

Blood samples were taken from calves with respiratory disease the first day of examination for determination of the serum concentration of haptoglobin, fibrinogen, alpha-2- and gamma-globulins, and ... [more ▼]

Blood samples were taken from calves with respiratory disease the first day of examination for determination of the serum concentration of haptoglobin, fibrinogen, alpha-2- and gamma-globulins, and albumin. A clinical examination was performed daily for the duration of the disease. The animals were retrospectively classified in two categories: those animals requiring no treatment or antibiotics alone (group A), and antibiotics associated to anti-inflammatory drugs (group B). The serum proteins were tested in order to check whether they were able to distinguish, on the first day of clinical examination, between calves requiring anti-inflammatory treatment (group B) or not (group A). About 80% of calves were properly classified in both groups by the combined use of the two serum proteins haptoglobin and fibrinogen: these two proteins, and especially haptoglobin, were useful for the identification of calves requiring an anti-inflammatory treatment. [less ▲]

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See detailComparison between three therapeutic strategies in the bovine respiratory disease complex
Boutet, Philippe ULg; Coghe, J.; Borceux, J. P. et al

in Pflügers Archiv : European Journal of Physiology (2002), 443

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See detailRecent advances in bovine pneumology
Lekeux, Pierre ULg; Borceux, J.; Boutet, Philippe ULg et al

in Kaske, Martin; Scholz, Henner; Höltershinken, Martin (Eds.) Recent developments and perspectives in bovine medicine (2002)

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See detailResuscitation procedures to improve perinatal adaptation in calves
Uysterpruyst, C. H.; Coghe, J.; Dorts, T. H. et al

in Proceedings : XXIIth World Buiatrics Congress (2002)

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See detailNuove strategie per migliorare l'efficacia della terapia nella sindrome respiratoria bovina negli animali da allevamento
Lekeux, Pierre ULg; Coghe, J.; Boutet, Philippe ULg

in Proceedings: 4° Congresso Nazionale Multisala SIVAR (2002)

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See detailSpirometric performance in Belgian Blue calves: I. Effects on economic losses due to the bovine respiratory disease complex.
Bureau, Fabrice ULg; Detilleux, Johann ULg; Dorts, T. et al

in Journal of Animal Science (2001), 79(5), 1301-1304

The aim of this study was to determine whether high spirometric performances in calves are associated with low economic losses due to the bovine respiratory disease complex (BRDC). Five spirometric ... [more ▼]

The aim of this study was to determine whether high spirometric performances in calves are associated with low economic losses due to the bovine respiratory disease complex (BRDC). Five spirometric variables (SV) were measured in 909 double-muscled Belgian Blue calves from 15 to 60 d of age. Afterward, calves were monitored for 6 mo to determine whether they developed BRDC and to determine the costs due to BRDC (i.e., medicine costs and veterinarians' fees, plus estimated financial losses due to mortality in case of death). To analyze the effects of spirometric performances on BRDC cost, a fixed linear model was used for each SV. In addition to SV, each model included the effects of sex, dam's parity, vaccination status, muscular development score, herd-period, and BW. Only herd-period and the maximal ventilation and the vital capacity had significant effects on costs due to BRDC, indicating that these two SV are major physiological determinants of economic losses associated with BRDC. Accordingly, it is assumed that an amelioration of maximal ventilation and vital capacity could result in increased resistance to BRDC in calves. [less ▲]

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See detailSpirometric performance in Belgian Blue calves: II. Analysis of environmental factors and estimation of genetic parameters.
Bureau, Fabrice ULg; Michaux, C.; Coghe, J. et al

in Journal of Animal Science (2001), 79(5), 1162-1165

Genetic parameters and environmental effects for spirometric variables (SV) in calves were estimated using 734 Belgian Blue calves (15 to 297 d of age), sired by 20 AI bulls. For each calf, the following ... [more ▼]

Genetic parameters and environmental effects for spirometric variables (SV) in calves were estimated using 734 Belgian Blue calves (15 to 297 d of age), sired by 20 AI bulls. For each calf, the following SV were measured: 1) the average ventilation (l/min) recorded during the 15 s of maximal ventilatory changes induced by lobeline administration (0.25 mg/kg, i.v.) (15-s MV(L)); 2) the vital capacity, and the maximal peak expiratory and inspiratory flows recorded after lobeline administration; and 3) the ventilatory reserve (15-s MV(L) - ventilation at rest). Analysis of environmental factors showed age of calf, herd, sex, and vaccination status had significant effects on SV. A sire model and a multiple-trait derivative-free REML procedure were used to estimate genetic parameters for SV, body weight, and muscling score. Heritabilities for SV ranged from 0.28 +/- 0.11 to 0.44 +/- 0.16. Genetic correlations among SV varied from 0.76 to 0.98 and environmental correlations from 0.69 to 0.80. Genetic correlations of SV with body weight (0.25 to 0.56) and with muscling score (0.21 to 0.76) were positive, as were environmental correlations of SV with body weight (0.44 to 0.70) and muscling score (0.09 to 0.25). These results suggest that selection may improve SV without impairing other traits of economic importance. [less ▲]

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See detailRespiratory adaptation to extra uterine life in healthy newborn calves
Uysterpruyst, C. H.; Reinhold, P.; Coghe, J. et al

in European Respiratory Journal (2000), 16(suppl 31), 300

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See detailValue of technegas for ventilation imaging in calf
Votion, Dominique ULg; Coghe, J.; Lekeux, Pierre ULg

in European Journal of Nuclear Medicine (2000), 27

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See detailSpirometric Variables Recorded after Lobeline Administration in Healthy Friesian and Belgian White and Blue Calves: Normal Values and Effects of Somatic Growth
Bureau, Fabrice ULg; Uystepruyst, C. H.; Coghe, J. et al

in Veterinary Journal (1999), 157(3), 302-308

The purposes of the present study were: (1) to develop original equations to predict spirometric variables (SV) in healthy Friesian and Belgian White and Blue (BWB) calves < 1 year of age; and (2) to ... [more ▼]

The purposes of the present study were: (1) to develop original equations to predict spirometric variables (SV) in healthy Friesian and Belgian White and Blue (BWB) calves < 1 year of age; and (2) to determine the effects of somatic growth on SV. Sixty-seven Friesian and 500 BWB calves were investigated. For each calf, the following SV were calculated: (1) the average minute volume derived using all the ventilatory cycles recorded during the 15 s of maximal ventilatory changes induced by lobeline administration (0.25 mg/kg, i.v.) (15-s LMV); (2) the maximal tidal volume, the maximal peak expiratory flow and the maximal peak inspiratory flow recorded from single breaths after lobeline administration (MVTL, MPEFLand MPIFL, respectively); (3) the ventilatory reserve (VRL= 15-s LMV - VEr; VEr= minute volume at rest). Mass specific (s) values were also calculated. All SV changed linearly with somatic growth in both Friesian and BWB calves. Since the rise in SV was more related to body weight than the age of calves, equations for reference values of SV always had body weight as the only independent variable. In the youngest calves, s SV were lower in the BWB breed. In the oldest calves (i.e. 1 year of age), s MPEFLand s MPIFLremained small in BWB calves whereas s MVTL, s 15-s LMV and s VRLwere almost equal in both breeds. These results could be related to the lower resistance to respiratory disorders in BWB calves < 1 year of age than in Friesian calves < 1 year of age. [less ▲]

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See detailMaximal Ventilation Assessment in Healthy Calves
Bureau, Fabrice ULg; Coghe, J.; Uystepruyst, C. H. et al

in Veterinary Journal (1999), 157(3), 309-314

In order to define a reliable method for estimating maximal ventilation in cattle, 12 healthy calves underwent a rebreathing trial and injections of increasing doses of lobeline, a respiratory analeptic ... [more ▼]

In order to define a reliable method for estimating maximal ventilation in cattle, 12 healthy calves underwent a rebreathing trial and injections of increasing doses of lobeline, a respiratory analeptic. The effects of these tests on the main ventilatory parameters (tidal volume, VT; respiratory frequency, fR and minute volume,.VE) recorded during the 15 s of maximal response were studied and compared. The sharp rise in.VE(4.8 times higher than the resting value) observed during the rebreathing trial was mainly due to an increase in VT. This rise in ventilation was the highest ever reported in calves. Lobeline dose-dependently enhanced ventilation up to a threshold dose of 0.25 mg/kg, which always produced a maximal response. This maximal response (3.7 times higher than the resting value), reflecting both an increase in fR and VT, was reproducible at an interval of 12 h and was highly correlated with that observed during the rebreathing trial (R = 0.98, P< 0.001). These results suggest that: (1) rebreathing trial is a reliable method to induce and measure maximal ventilation in calves; and (2) lobeline administration (0.25 mg/kg) is a reliable means of accurately estimating this variable. Lobeline administration, unlike the rebreathing trial, is safe and easy to standardize, and the test therefore seems to be the preferred way of studying maximal ventilation in calves. [less ▲]

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See detailChanges in respiratory mechanics measured by IOS during the first day of life in calves
Uystepruyst, Ch; Reinhold, P.; Coghe, J. et al

in Proceedings: 17th Symposium of the Comparative Respiratory Society (1999)

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See detailRelationships between spirometric performances and occurrence and severity of respiratory disease in Belgian Blue calves
Bureau, Fabrice ULg; Fievez, Laurence ULg; Detilleux, J. et al

in Proceedings: 17th Symposium of the Comparative Respiratory Society (1999)

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See detailCorrelation between the neutralizing response to BRSV vaccinal strains and the prevention of pulmonary dysfunction induced by a challenge strain
Bureau, Fabrice ULg; Genicot, B.; Coghe, J. et al

in Proceedings: Réunion de la Société Belge de Physiologie et de Pharmacologie Fondamentales et Cliniques (1999)

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See detailLung scanning in calves using technegas
Votion, Dominique ULg; Coghe, J.; Lekeux, Pierre ULg

in Plügers Archives European Journal of Physiology (1998)

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See detailEstimation of the heritability of spirometric variables in calves
Bureau, Fabrice ULg; Coghe, J.; Uystepruyst, Christophe et al

in Pflügers Archiv : European Journal of Physiology (1998), 435

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See detailPotential of maximal ventilation as a sire selection criterion to reduce respiratory disease severity in beef cattle
Bureau, Fabrice ULg; Uystepruyst, Ch; Coghe, J. et al

in Proceedings: 16th Comparative Respiratory Society Meeting (1998)

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