References of "Cleuter, Yvette"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailDeep sequencing reveals abundant non-canonical retroviral microRNAs in B-cell leukemia/lymphoma
Rosewick, Nicolas; Momont, Mélanie ULg; Durkin, Keith ULg et al

in Proceedings of the National Academy of Sciences of the United States of America (2013)

Viral tumor models have significantly contributed to our understanding of oncogenic mechanisms. How transforming delta-retroviruses induce malignancy however remains poorly understood, especially as viral ... [more ▼]

Viral tumor models have significantly contributed to our understanding of oncogenic mechanisms. How transforming delta-retroviruses induce malignancy however remains poorly understood, especially as viral mRNA/protein are tightly silenced in tumors. Here, using deep sequencing of broad windows of small RNA sizes in the Bovine Leukemia Virus ovine model of leukemia/lymphoma, we provide in vivo evidence of the production of non-canonical Pol IIItranscribed viral microRNAs in leukemic B-cells in the complete absence of Pol II 5’ LTR-driven transcriptional activity. Processed from a cluster of five independent self-sufficient transcriptional units located in a proviral region dispensable for in vivo infectivity, BLV microRNAs represent ~ 40 % of all microRNAs in both experimental and natural malignancy. They are subject to strong purifying selection and associate with Argonautes, consistent with a critical function in silencing of important cellular and/or viral targets. BLV microRNAs are strongly expressed in preleukemic and malignant cells in which structural and regulatory gene expression is repressed, suggesting a key role in tumor onset and progression. Understanding how Pol III-dependent microRNAs subvert cellular and viral pathways will contribute in deciphering the intricate perturbations that underlie malignant transformation. [less ▲]

Detailed reference viewed: 100 (26 ULg)
Peer Reviewed
See detailViral expression in bovine leukemia virus-induced tumor cells.
Van Den Broeke, Anne; Cleuter, Yvette; Portetelle, Daniel ULg et al

in Developments in Biological Standardization (1990), 72

Detailed reference viewed: 4 (0 ULg)
See detailEven transcriptionally competent proviruses are silent in bovine leukemia virus-induced sheep tumor cells.
Van Den Broeke, Anne; Cleuter, Yvette; Chen, G. et al

in Modern trends in human leukemia VIII (R. Neth., ed.), Springer Verlag, Berlin (1989)

Detailed reference viewed: 4 (0 ULg)
Peer Reviewed
See detailUltrastructural demonstration of retrovirus antigens with immunogold staining in prodromal acquired immune deficiency syndrome.
Feremans, W.; Menu, R.; Goldman, M. et al

in Journal of Clinical Pathology (1985), 37

Detailed reference viewed: 14 (0 ULg)
Peer Reviewed
See detailImmunological reactivity of the Bovine Leukemia Virus glycoprotein gp51.
Portetelle, Daniel ULg; Bruck, Claudine; Cleuter, Yvette et al

in Straub O.C. (Ed.) Current Topics in Veterinary Medicine and Animal Science (1982)

Detailed reference viewed: 2 (0 ULg)
See detailExpression of rabbit globin mRNA injected into fused HeLa cells.
Huez, Georges; Bruck, Claudine; Portetelle, Daniel ULg et al

in Celis, J. E.; Graessmann, A.; Loyter, A. (Eds.) Transfer of Cell Constituents into Eukaryotic Cells (1980)

Detailed reference viewed: 2 (0 ULg)
Peer Reviewed
See detailGenomic integration of bovine leukemia provirus and lack of viral RNA expression in the target cells of cattle with different responses to BLV infection.
Kettmann, Richard; Marbaix, Gérard; Cleuter, Yvette et al

in Leukemia Research (1980), 4

Detailed reference viewed: 6 (1 ULg)
See detailExpression of rabbit globin mRNA injected into fused HeLa cells.
Huez, Georges; Bruck, Claudine; Portetelle, Daniel ULg et al

in Celis, J. E.; Graessmann, A.; Loyter, A. (Eds.) Transfer of Cell Constituents into Eukaryotic Cells (1980)

Detailed reference viewed: 4 (0 ULg)
Peer Reviewed
See detailTranslation of rabbit globin mRNA upon injection into fused HeLa cells
Huez, Georges; Bruck, Claudine; Portetelle, Daniel ULg et al

in FEBS Letters (1980), 109

Detailed reference viewed: 3 (0 ULg)
Peer Reviewed
See detailHumoral antibody response to bovine leukemia virus infection in cattle and sheep.
Bex, Françoise; Bruck, Claudine; Mammerickx, Marc et al

in Cancer Research (1979), 39(3), 1118-1123

Detailed reference viewed: 8 (0 ULg)
See detailMorphogenesis of bovine leukemia virus (BLV).
Dekegel, D.; Mammerickx, Marc; Burny, Arsène et al

in Burny, Arsène (Ed.) Bovine leukosis: various methods of molecular virology (1977)

Detailed reference viewed: 9 (2 ULg)
Peer Reviewed
See detailSynthesis and complete processing of a high-molecular-weight precursor polypeptide to viral structural proteins in toad oocytes micro-injected with avian myeloblastosis virus ribonucleic acid.
Ghysdael, Jacques; Hubert, E.; Travnicek, M. et al

in Biochemical Society Transactions (1977), 5

Detailed reference viewed: 9 (6 ULg)
Peer Reviewed
See detailFrog oocytes synthesize and completely process the precursor polypeptide to virion structural proteins after microinjection of avian myeloblastosis virus
Ghysdael, Jacques; Hubert, E.; Travnicek, M. et al

in Proceedings of the National Academy of Sciences of the United States of America (1977), 74(8), 3230-3234

Detailed reference viewed: 7 (0 ULg)
See detailPurification of bovine leukemia virus gp70 and bovine leukemia virus p24. Detection by radioimmunoassay of antibodies directed against these antigens.
Portetelle, Daniel ULg; Mammerickx, Marc; Bex, Françoise et al

in Burny, Arsène (Ed.) Bovine leukosis: various methods of molecular virology (1977)

Detailed reference viewed: 9 (1 ULg)
Peer Reviewed
See detailBovine leukemia virus, an exogenous RNA oncogenic virus.
Kettmann, Richard ULg; Portetelle, Daniel ULg; Mammerickx, Marc et al

in Proceedings of the National Academy of Sciences of the United States of America (1976), 73

Detailed reference viewed: 15 (1 ULg)
Peer Reviewed
See detailBovine leukemia virus, an exogenous RNA oncogenic virus.
Kettmann, Richard ULg; Portetelle, Daniel ULg; Mammerickx, Marc et al

in Modern trends in human leukemia II (1976), 19

Detailed reference viewed: 12 (0 ULg)