References of "Cieckiewicz, Ewa"
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See detailChemical analyses of the seeds from Prunella vulgaris: A chemotaxonomic approach
Paul, Aman ULg; Frederich, Michel ULg; Cieckiewicz, Ewa ULg et al

Poster (2014, April)

Common self-heal (Prunella vulgaris) plants are traditionally sown along the border of crops to enhance the biodiversity. Besides enhancing the biodiversity, they can also be a source of interesting ... [more ▼]

Common self-heal (Prunella vulgaris) plants are traditionally sown along the border of crops to enhance the biodiversity. Besides enhancing the biodiversity, they can also be a source of interesting compounds which could be important for food, pharmaceutical and cosmetic industries. The seeds of Common Yarrow were investigated for proteins, fatty acid compositions and polyphenolic compounds. The protein content was analyzed according to Dumas method, the extraction of oil was done using a cold extraction technique employing 2:1 chloroform/methanol as solvent, the fatty acid composition was determined using the gas chromatography and the amount of polyphenolic compounds were estimated using the method as described in European Pharmacopoeia, 8th edition. Common self-heal seeds can be of great commercial importance. [less ▲]

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See detailPotential anticancer activity of young Carpinus betulus leaves
Cieckiewicz, Ewa ULg; Angenot, Luc ULg; Gras, T et al

in Planta Medica (2012, August), 78(11), 1178

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See detailPotential anticancer activity of young Carpinus betulus leaves.
Cieckiewicz, Ewa ULg; Angenot, Luc ULg; Gras, T. et al

in Phytomedicine : International Journal of Phytotherapy and Phytopharmacology (2012), 19(3/4), 278-284

As part of our continuing research for anticancer compounds from the Walloon Region forest, EtOAc extract from Carpinus betulus leaves was phytochemically studied, leading to the bioguided isolation of ... [more ▼]

As part of our continuing research for anticancer compounds from the Walloon Region forest, EtOAc extract from Carpinus betulus leaves was phytochemically studied, leading to the bioguided isolation of pheophorbide a, which is responsible of anticancer properties of C. betulus young leaves. This compound was identified using nuclear magnetic resonance and mass spectrophotometric data and comparison with a commercial standard. Evaluation of the growth inhibitory activities of pheophorbide a using MTT colorimetric assay and phase-contrast microscopy in various human cancer cell lines confirmed the photoactivable properties of this compound. Our research showed, for the first time, the presence of pheophorbide a, a chlorophyll derived compound, which we quantified in high quantities in young leaves of C. betulus. This is in contrast with the literature which generally describes pheophorbide a as a catabolic product of chlorophyll, then preferentially present in old leaves. [less ▲]

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See detailIn Vitro Anticancer Potential of Tree Extracts from the Walloon Region Forest.
Frederich, Michel ULg; Marcowycz, Aline; Cieckiewicz, Ewa ULg et al

in Planta Medica (2009), 75(15), 1634-1637

Forty-eight extracts from 16 common Belgian trees from the Walloon Region forest were evaluated for IN VITRO growth inhibitory activity against the human LoVo colon cancer, PC3 prostate cancer, and U373 ... [more ▼]

Forty-eight extracts from 16 common Belgian trees from the Walloon Region forest were evaluated for IN VITRO growth inhibitory activity against the human LoVo colon cancer, PC3 prostate cancer, and U373 glioblastoma cell lines. Our study was performed with the aim of selecting plant candidates in order to later isolate new anticancer compounds from an easily affordable tree material. Extracts from ALNUS GLUTINOSA (stem bark), CARPINUS BETULUS (leaves and stem bark), CASTANEA SATIVA (stem bark), FAGUS SYLVATICA (leaves), ILEX AQUIFOLIUM (leaves), LARIX DECIDUA (leaves), QUERCUS PETRAEA (stem bark), and QUERCUS ROBUR (leaves) showed for the first time potent IN VITRO growth inhibitory activity and could become easily affordable sources of potential new anticancer agents. Root extracts from ROBINIA PSEUDOACACIA, already known for containing cytotoxic lectins, also showed interesting activity. [less ▲]

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