References of "Chai, Yoke Chin"
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See detailAssessing local Ca2+ concentrations in calcium phosphate scaffolds by computational modelling
Manhas, Varun ULg; Guyot, Yann ULg; Chai, Yoke Chin et al

Poster (2013, October 24)

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See detailA MODEL FOR CELL/MATRIX GROWTH ON 3D SURFACES: A COUPLING OF LEVEL SET METHOD AND BRINKMAN EQUATION
Guyot, Yann ULg; Papantoniou, Ioannis; Chai, Yoke Chin et al

Conference (2013, September 11)

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See detailMULTIPHYSICS MODELING OF CELL/MATRIX GROWTH ON 3D STRUCTURES.
Guyot, Yann ULg; Papantoniou, Ioannis; Chai, Yoke Chin et al

Conference (2013, August 26)

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See detailA MATHEMATICAL MODEL FOR CELL/MATRIX GROWTH ON 3D SURFACES USING THE LEVEL SET METHOD.
Guyot, Yann ULg; Papantoniou, Ioannis; Chai, Yoke Chin et al

Conference (2013, April 03)

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See detailIn vitro and in vivo comparative study of material properties crucial for reverse engineering of calcium phosphate scaffolds
Chai, Yoke Chin; Kerckhofs, Greet ULg; Bertels, Jeroen et al

Conference (2013)

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See detailMathematical Level-Set Modelling of Cell Growth on 3D Surfaces
Guyot, Yann ULg; Papatoniou, Ioannis; Chai, Yoke Chin et al

Poster (2012, September)

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See detailEctopic bone formation by 3D porous calcium phosphate-Ti6Al4V hybrids produced by perfusion electrodeposition.
Chai, Yoke Chin; Kerckhofs, Greet ULg; Roberts, Scott J. et al

in Biomaterials (2012), 33(16), 4044-58

Successful clinical repair of non-healing skeletal defects requires the use of bone substitutes with robust bone inductivity and excellent biomechanical stability. Thus, three-dimensionally functionalised ... [more ▼]

Successful clinical repair of non-healing skeletal defects requires the use of bone substitutes with robust bone inductivity and excellent biomechanical stability. Thus, three-dimensionally functionalised porous calcium phosphate-Ti6Al4V (CaP-Ti) hybrids were produced by perfusion electrodeposition, and the in vitro and in vivo biological performances were evaluated using human periosteum derived cells (hPDCs). By applying various current densities at the optimised deposition conditions, CaP coatings with sub-micrometer to nano-scale porous crystalline structures and different ion dissolution kinetics were deposited on the porous Ti6Al4V scaffolds. These distinctive physicochemical properties caused a significant impact on in vitro proliferation, osteogenic differentiation, and matrix mineralisation of hPDCs. This includes a potential role of hPDCs in mediating osteoclastogenesis for the resorption of CaP coatings, as indicated by a significant down-regulation of osteoprotegerin (OPG) gene expression and by the histological observation of abundant multi-nucleated giant cells near to the coatings. By subcutaneous implantation, the produced hybrids induced ectopic bone formation, which was highly dependent on the physicochemical properties of the CaP coating (including the Ca(2+) dissolution kinetics and coating surface topography), in a cell density-dependent manner. This study provided further insight on stem cell-CaP biomaterial interactions, and the feasibility to produced bone reparative units that are predictively osteoinductive in vivo by perfusion electrodeposition technology. [less ▲]

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See detailCalcium phosphate scaffolds customizations for bone tissue engineering applications
Carlier, Aurélie ULg; Chai, Yoke Chin; Theys, Tina et al

Poster (2011, November 18)

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See detailAn integrative model based approach to optimize calcium phosphate scaffold-stem cell combinations
Carlier, Aurélie ULg; Chai, Yoke Chin; Theys, Tina et al

Poster (2011, June 07)

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See detailOptimization of calcium phosphate scaffold-cell combinations using an integrative model based approach
Carlier, Aurélie ULg; Chai, Yoke Chin; Theys, Tina et al

in International Conference on Tissue Engineering (ECCOMAS) - proceedings (2011, June 03)

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See detailThe use of micro-CT to correlate in-vitro cell behaviour with the surface roughness of Ti6Al4V scaffolds for tissue engineering
Pyka, Grzegorz; Kerckhofs, Greet ULg; Chai, Yoke Chin et al

in Abstract book SkyScan User Meeting 2011 (2011)

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See detailComputational modelling of calcium mediated bone regeneration
Carlier, Aurélie ULg; Chai, Yoke Chin; Theys, Tina et al

Poster (2010, November 26)

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See detailA mathematical model of calcium ion influence on the activity of osteogenic cells
Carlier, Aurélie ULg; Chai, Yoke Chin; Theys, Tina et al

Poster (2010, November 19)

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See detailA mathematical model of calcium ion influence on the activity of osteogenic cells
Carlier, Aurélie ULg; Chai, Yoke Chin; Theys, Tina et al

Poster (2010, November 19)

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