References of "Cerri, Simona"
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See detailAtrial Natriuretic Peptide in cardiac horses
Leroux, Aurélia ULg; Al-Haidar, Ali; Remy, Benoît ULg et al

in Voorjaarsdagen Proceedings (2014, April 17)

Background: Natriuretic peptides are cardiac biomarkers that have been shown to have high potential for diagnosis, prognosis, and guidance of treatment in human and small animal cardiology. However, their ... [more ▼]

Background: Natriuretic peptides are cardiac biomarkers that have been shown to have high potential for diagnosis, prognosis, and guidance of treatment in human and small animal cardiology. However, their diagnostic and prognosis value in the equine species has only been studied in a limited number of cases. Objective: To investigate the plasma atrial natriuretic peptide concentration (ANPPl) in a large group of horses with various degrees of valvular regurgitation (VR) and heart failure (HF). Animals: Ninety-one horses, admitted at the equine teaching hospital of the University of Liege, and with no, mild, moderate or severe VR and presenting various stages of HF, according to human and canine grading system (A: no VR, B1: asymptomatic VR without cardiac remodelling, B2: asymptomatic VR with cardiac remodelling, C: symptomatic VR). Methods: All horses underwent clinical and Doppler echocardiographic examination, which allowed determining the presence, nature, and severity of VR, and the HF stage. The ANPPl was measured using a commercially available human RIA test. The mean values of body weight, age, ANPPl and each echocardiographic parameter were compared between horses in stage A, B1, B2 or C of HF and between horses with no, mild, moderate or severe VR, using a one-way ANOVA test. Then, correlations between ANPPl and each echocardiographic parameter were assessed using a Pearson’s product-moment analysis. Results: Horses with severe and moderate VR had significantly higher ANPPl than horses with mild or no VR. ANPPl was significantly higher in horses at stage B2 and C of HF than horses at stage A and B1. Moreover, ANPPl was significantly correlated with most of the measured echocardiographic variables. This correlation was especially strong with the left atrial diameter and its percentage of dilation. Conclusions and Clinical Importance: Those results suggest that ANPPl in horses suffering from VR could have a high diagnostic value of HF, especially in horses with tricuspid or mitral insufficiency and with enlargement or dysfunction of the atria. [less ▲]

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See detailUse of automatic stapling device during castration to prevent (re)occurrence of inguinal hernia in horses with large vaginal rings.
Salciccia, Alexandra ULg; de la Rebière de Pouyade, Geoffroy ULg; Ponthier, Jérôme ULg et al

in Journal of Equine Veterinary Science (2014, January), 34(1), 99-100

(Re)ocurrence of inguinal hernia in case of very large vaginal rings may simply be prevented by closure of the vaginal tunic by TA staples during castration by inguinal approach. This method provides a ... [more ▼]

(Re)ocurrence of inguinal hernia in case of very large vaginal rings may simply be prevented by closure of the vaginal tunic by TA staples during castration by inguinal approach. This method provides a good resistance to internal pressure, appears to be safe, fast and easy to perform and may therefore be an interesting alternative to laparoscopic techniques when castration is considered. [less ▲]

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See detailEffect of inhaled hysrosoluble curcumin in lipopolysaccharide-induced lung neutrophilia in horses
Sandersen, Charlotte ULg; Cerri, Simona ULg; Franck, Thierry ULg et al

in Dorothy Russel Havemeyer Foundation IAD Workshop (2014)

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See detailAtrial Natriuretic Peptide as an indicator of the severity of valvular regurgitation and heart failure in horses
Leroux, Aurélia ULg; Al Haidar, Ali; Remy, Benoît ULg et al

in Journal of Equine Veterinary Science (2014), in press

Natriuretic peptides are cardiac biomarkers, routinely used for diagnosis, prognosis, and guidance for treatment in human and small animal cardiology. However, their diagnostic and prognostic value in ... [more ▼]

Natriuretic peptides are cardiac biomarkers, routinely used for diagnosis, prognosis, and guidance for treatment in human and small animal cardiology. However, their diagnostic and prognostic value in horses has received little study. The aim of this study was to investigate the plasma atrial natriuretic concentration (ANPPl) in a large group of horses with various degrees of valvular regurgitation (VR) and congestive heart failure (CHF). Clinical examination and two-dimensional, time-motion mode and Doppler echocardiography were performed on 91 horses admitted to the Equine Teaching Hospital of Liege University, with either no, mild, moderate or severe VR and presenting various stages of CHF. ANPPl was measured using a commercially available human RIA test. Mean values of body weight, age, ANPPl and echocardiographic parameters were compared between horses with no, mild, moderate and severe VR and between horses in different CHF stages. Correlation and linear regression of ANPPl with each echocardiographic parameter and with the percentage of dilation of each of cardiac chambers were assessed. Horses with severe or moderate VR had significantly higher ANPPl than horses with mild or no VR. ANPPl was significantly higher in horses presenting CHF than in horses without CHF. ANPPl was significantly correlated with the left atrial diameter and its percentage of dilation. These results suggest a diagnostic value of ANPPl in horses with VR, especially with tricuspid or mitral insufficiency with dilation of the atria. [less ▲]

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See detailÉtiopathogénie de la myopathie atypique et gestion raisonnée des cas
Votion, Dominique ULg; Patarin, Florence; Cerri, Simona ULg et al

in In Proceedings: Journée AVEF (Association des Vétérinaires Equins Français) (2013, December)

Atypical myopathy is an acute intoxication resulting from the ingestion of a toxin contained in the seeds of some trees of the genus Acer (i.e. « maple trees »). The causes of the emergence of the disease ... [more ▼]

Atypical myopathy is an acute intoxication resulting from the ingestion of a toxin contained in the seeds of some trees of the genus Acer (i.e. « maple trees »). The causes of the emergence of the disease due to trees naturalized for many decades remain undetermined. Currently, there is no cure for atypical myopathy but symptomatic treatment may be revisited on the basis of knowledge of the aetio-pathogenesis of the disease. This paper compiles recommendations following a discussion on treatment of atypical myopathy held in October 2013 at the University of Liege (Belgium) to provide emergency treatment distinguishing clinical management (1) at hospital, (2) in the field and (3) preventive measures to protect pasture companions. [less ▲]

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See detailImaging findings in 12 horses with lymphoma: a retrospective study
Evrard, Laurence ULg; Fonseca, Rita; Bolen, Géraldine ULg et al

Poster (2013, February)

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See detailTraditional and quantitative assessment of acid-base and shock variables in horses with atypical myopathy
van Galen, G; Cerri, Simona ULg; Porter, S et al

in Journal of Veterinary Internal Medicine (2013), 27(1), 186-193

BACKGROUND: Descriptions of acid-base disturbances in atypical myopathy (AM) are limited. OBJECTIVES: Describe and compare traditional and quantitative acid-base abnormalities and cardiovascular shock ... [more ▼]

BACKGROUND: Descriptions of acid-base disturbances in atypical myopathy (AM) are limited. OBJECTIVES: Describe and compare traditional and quantitative acid-base abnormalities and cardiovascular shock status in horses with AM at admission. ANIMALS: 34 horses with AM, 15 healthy controls. METHODS: Retrospective case-control study. Records were searched for shock variables (packed cell volume [PCV], blood urea nitrogen [BUN], heart and respiratory rate) and acid-base variables (venous blood gas analysis, electrolytes, total protein, lactate) on admission. Base excess (BE) of free water (BEfw), chloride (BEcl), total protein (BEtp), and unidentified anions (BEua), anion gap (AG), measured strong ion difference (SIDm), and concentration of total nonvolatile weak acids ([Atot]) were calculated. Acid-base classifications, using simplified strong ion model and traditional approach, and shock grades were assigned. A 2-sample Wilcoxon rank-sum test and Bonferroni correction compared variables in AM cases versus control horses. Significance was P < .05/16 for acid-base and P < .05/5 for shock variables. RESULTS: Tachycardia, tachypnea, and normal to increased PCV and BUN were common in AM cases. Respiratory, metabolic acid-base alterations, or both were mainly caused by respiratory alkalosis, lactic acidosis, and SIDm alkalosis, alone or in combination. Evaluated variables (except pH, potassium concentration, total protein, and related calculations) were significantly different (P < .001) between AM cases and control horses. The strong ion model provided a more accurate assessment than the traditional approach and identified mixed derangements. CONCLUSIONS AND CLINICAL IMPORTANCE: Acid-base derangements should be evaluated in horses with AM and this preferably with the strong ion model. [less ▲]

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See detailRelationship between echocardiographic measurements and body size in horses.
Al Haidar, Ali; Leroux, Aurélia ULg; Borde, Laura ULg et al

in Journal of Equine Veterinary Science (2013), 33(2), 107-114

The objectives of this work were to evaluate the optimal body size variable, and to determine mathematical model that best fits echocardiographic measurements to body size in the equine species. 150 ... [more ▼]

The objectives of this work were to evaluate the optimal body size variable, and to determine mathematical model that best fits echocardiographic measurements to body size in the equine species. 150 horses of various breeds, aged 1 week to 17 years old, body weight (BW) 38 to 890 kg, and free from cardiac disease were used in this study. Based on their age (i.e. younger or older than 2 years), animals were separated into 2 groups. In each horse, the body weight (BW), height at withers (HT), thoracic circumference (TC) and the body length (BL) were measured, the body surface area (BSA) was calculated, and a standard two-dimensional and M-mode echocardiography was performed allowing classic cardiac measurements to be taken. Correlations between each echocardiographic measurement and each of the anthropometric variables were assessed via a Pearson’s product-moment analysis and using linear, logarithmic, and power regression analysis in all animals and within the 2 groups. The dimensional, but not the functional, echocardiographic measurements showed a close correlation with all body size variables, especially during growth. The relationship between cardiac measurements and body size was best described using power regression models with TC as the anthropometric variable, but the relationship was also very accurately described using BW, BSA, or BL. In the equine species, dimensional echocardiographic reference values should be established using power regression equations on TC. Such a correction for body size could increase the diagnostic value of echocardiography in equine cardiology. [less ▲]

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See detailEffect of breed, sex, age and body weight on Echocardiographic Measurements in the Equine Species
Al Haidar, Ali; Farnir, Frédéric ULg; Deleuze, Stefan ULg et al

in Research in Veterinary Science (2013), In press

Little is known about the effect of various animal's signalment variables on echocardiographic reference values in the equine species. This study was performed to evaluate the effect of sex, breed, age ... [more ▼]

Little is known about the effect of various animal's signalment variables on echocardiographic reference values in the equine species. This study was performed to evaluate the effect of sex, breed, age and body weight (BW) on echocardiographic measurements in the equine species. Echocardiography was performed on 212 ponies or horses of various breeds, aged from 1 day to 37 years old (mean ± SD: 7.8 ± 5.8 years), BW 38-890 kg (mean ± SD: 421 ± 133 Kg), and free of cardiac disease. Fifty of those animals aged from 2 months to 35 years old (mean ± SD: 11.6 ± 6.4 years old); BW 77-662 kg (mean ± SD: 436 ± 135 kg) were also examined using the pulsed-wave Doppler mode. Standard two-dimensional and M-mode echocardiography were performed on all animals. Standard pulsed-wave Doppler examination of each cardiac valve was performed on the 50 first examined animals. Data were analysed using a general linear model including the effect of sex, age, breed and BW after logarithmic transformation of the data. Therefore, the same analysis was performed separately on animals aged  2 years-old and on older animals. All dimensional echocardiographic measurements were significantly affected by BW and most of them were significantly affected by breed, but not by sex. Only the aortic and the pulmonary artery internal diameter were significantly affected by age. None of the Doppler measurements were significantly affected by the tested variables. In conclusion, in the equine species, dimensional echocardiographic reference values should be established using regression equations as a function of BW, which could increase the diagnostic value of this leading technique in equine cardiology. Breed could also have an effect on those measurements. [less ▲]

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See detailassessment of acid base imbalances in horses suffering from atypical myopathy
Van Galen, Gaby ULg; Cerri, Simona ULg; Porter, Sarah et al

in proceedings AAEP 2011 (2011, November 11)

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See detailExploratory survey on acid base derangements in horses suffering from atypical myopathy
Van Galen, Gaby ULg; Cerri, Simona ULg; Porter, Sarah et al

in Proceedings BEVA 2011 (2011, September 08)

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