References of "Caudron, Isabelle"
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See detailSensitivity and specificity of blood leukocyte counts as an indicator of mortality in horses after colic surgery
Salciccia, Alexandra ULg; Sandersen, Charlotte ULg; Grulke, Sigrid ULg et al

in Veterinary Record : Journal of the British Veterinary Association (2013), 173(11),

The objectives of this study were to describe and relate perioperative changes in blood leukocyte counts to the outcome of surgical colic horses, determine a cut-off value in the early postoperative ... [more ▼]

The objectives of this study were to describe and relate perioperative changes in blood leukocyte counts to the outcome of surgical colic horses, determine a cut-off value in the early postoperative period to obtain an indicator of the outcome, and compare the obtained value to a validation population of horses. Fifty-three horses undergoing colic surgery were included in the descriptive part of the study. Total leukocyte counts were performed before, during and serially after surgery. A receiver operating characteristic analysis was performed on the leukocyte counts of 45 of these horses to determine a cut-off value for the outcome. The results obtained were validated on a second set of 50 horses that underwent colic surgery in similar conditions. The kinetics of blood leukocytes in survivors was higher than in non-survivors during the first days. Non-survivor horses were more likely to have at least one blood leukocyte count ≤3.9×103/mm3 between 28 and 60 hours after surgery than survivor horses. This cut-off value was confirmed in the validation population. These results suggest that routine values of blood leukocyte counts can be used as an additional prognostic indicator after colic surgery alongside other predictors previously associated with the outcome. [less ▲]

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See detailAssociation of breeding conditions with prevalence of osteochondrosis in foals
Vander Heyden, Laurent ULg; Lejeune, Jean-Philippe ULg; Caudron, Isabelle ULg et al

in Veterinary Record : Journal of the British Veterinary Association (2013), 178

Osteochondrosis (OC) is the most common developmental orthopaedic disease in horses and represents a major problem to the horse industry. The complete mechanism of this multifactorial disease is not yet ... [more ▼]

Osteochondrosis (OC) is the most common developmental orthopaedic disease in horses and represents a major problem to the horse industry. The complete mechanism of this multifactorial disease is not yet elucidated, but it is accepted that OC lesions are the result of intrinsic genetic and external factors. The aim of the present work was to evaluate the relationship between breeding management and OC. Breeding conditions were recorded, and a radiological examination was performed in 223 foals. Feeding practice and housing management were analysed in a multivariate model to determine risk factors for OC in three periods: gestation, birth to weaning and weaning to one-year-old. The major breakthrough of this study is the significant relationship between OC development and (1) the maternal nutrition during gestation and (2) the type of housing of the foals during their first year. It appears that mares fed with concentrates during gestation are more likely to produce foals that are subsequently affected by OC compared with other mares (P<0.05). Foals housed exclusively at pasture until one year of age are significantly less affected than foals exclusively housed in box or, alternatively, in box and at pasture (P<0.05). These results underline the role of the energy metabolism and the level of exercise in the aetiologic process of the disease, and help to develop preventive strategies during the crucial period of gestation to one year of age of the foal. [less ▲]

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See detailRelationship between exercise-induced systemic inflammatory like reaction and racing performance in endurance horses
Serteyn, Didier ULg; Caudron, Isabelle ULg; Lejeune, Jean-Philippe ULg et al

in Comparative Exercise Physiology (2012), 8(3/4), 213218

This study showed that systemic inflammatory like reaction is not clearly related to performance but also to horse-related factors such as intinsic capacity or training.

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See detailHorseshoeing styles comparison and detection of subclinic equine digit discomfort during movement
Noble, Prisca ULg; Lejeune, Jean-Philippe ULg; Serteyn, Didier ULg et al

Conference (2011, July 07)

Introduction: For the sound equine forelimb, ground reaction force (GRF) peaks to ~0.8-1 BodyWeight (BW) during the trot (4m/s). Little work investigates the effect of different horsehoeing styles ... [more ▼]

Introduction: For the sound equine forelimb, ground reaction force (GRF) peaks to ~0.8-1 BodyWeight (BW) during the trot (4m/s). Little work investigates the effect of different horsehoeing styles, directly on the limb GRF distribution and indirectly on the equine digit comfort during movement. This study investigates GRF distribution after application of different aluminium horseshoeing styles during movement. Methods: Two horses (H1,H2; mean 575kg) were used. However H2 had an old healed flexor tendons lesion, the horses were judged to be sound on locomotor examination (without lameness). According to the rules that respect the foot biomechanical balance, they were trimmed and shod with a non-broken foot-pastern axis. On the day of the tests, they were led on a treadmill at a trot (4m/s). Kinetics were collected, using a F-Scan system, during 3 following sessions : to both forehooves after application of classic roller, eggbarr and equi+ horseshoes. For each session, data from 3 strides for each left forelimb of each horse were averaged and kinetics (GRF) were obtained. Results: For the classic roller, eggbarr and equi+ horseshoes, GRF peaked respectively to 0.57+-0.006;0.36+-0.005;0.83+-0.009BW for H1 and 0.61+-0.007;0.84+-0.007;0.51+-0.009BW for H2. Theses horseshoes loading differences show a dynamic load transfer from the forelimbs to the hindlimbs, that is the result of a subclinic (without lameness) equine digit discomfort during movement. Conclusions: Subclinic equine digit discomfort after application of horshoes has been detected using the F-Scan system during movement. These results confirm the interest of the equi+ horseshoes on horses without flexor tendon lesion. [less ▲]

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See detailHeel effects on joint contact force components in the equine digit : a sensitivity analysis
Noble, Prisca ULg; Lejeune, Jean-Philippe ULg; Caudron, Isabelle ULg et al

in Equine Veterinary Journal. Supplement (2010), 42

Reasons for performing study: Whereas the effect of heel configuration on the tension of the suspensory apparatus is well documented in the literature, there are few reports of joint contact force ... [more ▼]

Reasons for performing study: Whereas the effect of heel configuration on the tension of the suspensory apparatus is well documented in the literature, there are few reports of joint contact force components in the equine distal forelimb. Objectives: To improve understanding of the effect of heel configuration on equine digit joint loading, a sensitivity analysis was performed to compare the effect of a raised heel on joint contact force components in the coffin and fetlock joints during the stance phase of the trot. Materials and methods: FourWarmblood horses were used. An inverse dynamic analysis was carried out using kinematic and kinetic data. Taking into account the tendon wrapping forces (WF) around the sesamoid bones in the calculations, the joint contact forces (CF) were estimated for the coffin and fetlock joints during the trot stance phase (4 m/s). To test the sensitivity of the results to heel configuration changes, calculations were performed repeatedly for different heel configurations (raised by 0, 6 and 12°). A one-way ANOVA with repeated measures was used to test the effect of heel configuration (at the 3 levels) (a = 0.05; P<0.05; post hoc testing: Bonferroni). Results: For heel configurations raised from 0–12°: whereas the tension of the deep digital flexor tendon decreased and the tension of the superficial digital flexor tendon increased, for the coffin joint the peakWF(1.4 +- 0.25 bwt; 1.2 +- 0.2 bwt; 0.95 +- 0.1 bwt) and the peak CF (2.45 +- 0.25 bwt; 2.2 +- 0.2 bwt; 2 +- 0.1 bwt) decreased significantly (P<0.05). For the fetlock joint, the peak WF (3.8 +- 0.7 bwt; 4.1 +- 0.3 bwt; 4.4 0.25 bwt) and the peak CF (4.35 +- 0.7 bwt; 4.7 +- 0.35 bwt; 5 +- 0.3 bwt) increased, but not significantly. Conclusion: This analysis suggests that the coffin joint loading and fetlock joint loading are strongly connected. The heel configuration may influence both coffin joint and fetlock joint contact force components. [less ▲]

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See detailEffect of intensive exercise on plasmatic neutrophil elastase level in eventing and endurance horses
Lejeune, Jean-Philippe ULg; Sandersen, Charlotte ULg; Votion, Dominique ULg et al

in Equine Veterinary Journal. Supplement (2010), 48

Reasons for performing the study – Intensive exercise induces a systemic inflammatory response characterized by an increase of blood neutrophil count and myeloperoxidase (MPO) release. Neutrophil elastase ... [more ▼]

Reasons for performing the study – Intensive exercise induces a systemic inflammatory response characterized by an increase of blood neutrophil count and myeloperoxidase (MPO) release. Neutrophil elastase (NE) could also contribute to tissues lesions by their proteinase activities. Objective – To compare plasmatic NE concentrations before and after different forms of intensive exercise. Materials and Methods – EDTA blood samples were taken from 51 eventing horses (EvH) and 32 endurance horses (EndH) were sampled before the race (T0). Blood sampling was performed 2 h (T1) after completing either phase D of a one or two star eventing competition (n=51) or a 120 or 160 km endurance race (n=32). Plasmatic NE and MPO were measured by a specific equine ELISA. Neutrophil counts and creatine kinase (CK) levels were also measured. A Wilcoxon test for paired samples was used to compare mean values of neutrophils, CK, MPO and NE at T0 and T1 in EvH and in EndH. Correlations were calculated between all the 4 parameters in EvH and EndH. Results – At T0, mean NE levels were 14.43 ± 3.63 ng/ml for EvH and 11.7 ± 2.11 ng/ml for EndH. The competition induced a significant increase of NE levels in (58.57 ± 24.06 ng/mL) EvH and (95.74 ± 22.70 ng/mL) EndH (p < 0,05). NE was significantly (p < 0,0001) correlated to MPO in EvH (r = 0.293) and EndH (0.594) and to CK (r = 0.297) in EndH (p<0.0001). Neutrophils, CK and MPO were significantly increased between T0 and T1 in both types of horses. Conclusions – Significant increase of NE was observed after intense exercise with a significant correlation between NE and MPO. The huge variability in MPO and ELT, indicates, that not all horses show the same intensity of systemic inflammatory response. [less ▲]

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