References of "Cantineau, R"
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See detailChemical processing for the production of carrier free selenium-73 from germanium and arsenic targets and synthesis of L-[73Se]selenomethionine.
Plenevaux, Alain ULg; Guillaume, M.; Brihaye, C. et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1991), 30

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See detailNCA synthesis of an N-w-[18F]fluoroethyl analog of altanserine, a serotonine S2 receptor ligand.
Lemaire, Christian ULg; Damhaut, Ph.; Cantineau, R. et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1991), 30

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See detailRoutine production and improvement in the purification of 3-N-(2'-[18F]fluoroethyl)spiperone for clinical use.
Plenevaux, Alain ULg; Cantineau, R.; Labar, D. et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1991), 30

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See detailNCA asymmetric synthesis of 6-[18F]fluoro-L-dopa.
Lemaire, Christian ULg; Guillaume, M.; Cantineau, R. et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1991), 30

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See detail18F-substituted aromatic aldehydes, key intermediates for nca radiosyntheses.
Lemaire, Christian ULg; Guillaume, M.; Plenevaux, Alain ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1991), 30

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See detailSynthesis and preliminary animal studies of [131I]iodotropapride: a cerebral dopamine D2 receptor ligand.
Cantineau, R.; Damhaut, Ph.; Plenevaux, Alain ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1991), 30

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See detailAsymmetric synthesis of 4-[18F]fluoro-L-m-tyrosine via aromatic fluorination.
Lemaire, Christian ULg; Damhaut, Ph.; Plenevaux, Alain ULg et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1991), 32

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See detailSerotonine-S2 receptor imaging with [18F]altanserin and PET. Results in young normal controls.
Sadzot, Bernard ULg; Lemaire, Christian ULg; Cantineau, R. et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1991), 32

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See detail4-[18F]Fluorotropapride, a specific D2 receptor ligand for PET.
Damhaut, Ph.; Cantineau, R.; Lemaire, Christian ULg et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1991), 32

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See detail2 and 4-[18F]fluorotropapride, two specific D2 receptor ligand for PET.
Damhaut, Ph.; Cantineau, R.; Lemaire, Christian ULg et al

in European Journal of Nuclear Medicine (1991), 18

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See detail[131I]iodotropapride: a cerebral dopamine D2 receptor ligand.
Cantineau, R.; Damhaut, Ph; Plenevaux, Alain ULg et al

Poster (1990, August 26)

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See detailNo-Carrier-Added Regioselective Preparation of 6-[18f]Fluoro-L-Dopa
Bozet, Claire ULg; Guillaume, Marcel; Cantineau, R. et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1990), 31(7), 1247-51

This paper describes the preparation of 6-[18F]fluoro-L-dopa by a no-carrier-added method based on the nucleophilic displacement of nitro groups of two commercially available substrates, 3,4-dimethoxy-2 ... [more ▼]

This paper describes the preparation of 6-[18F]fluoro-L-dopa by a no-carrier-added method based on the nucleophilic displacement of nitro groups of two commercially available substrates, 3,4-dimethoxy-2-nitrobenzaldehyde (nitroveratraldehyde) and 6-nitropiperonal. Fluorination was conducted in DMSO with fluorine-18 (18F) in the presence of the aminopolyether Kryptofix 222 and potassium carbonate. The condensation of the fluorinated aldehydes with phenyloxazolone and the subsequent hydrolysis with HI/P yield, after purification by HPLC, only the 6-(D, L) isomers. The racemic mixture (50/50) was resolved on an analytical scale chiral column. The method, which requires 100 min (EOB) to complete, produces 6-[18F]fluoro-L-dopa with a decay-corrected radiochemical yield of 10%, an enantiomeric purity greater than 99%, and a specific activity of 1.2 Ci/mumole. [less ▲]

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See detailImaging serotonin-S2 receptors in humans with PET and the selective S2 antagonist [18F]altanserin. Preliminary results.
Sadzot, Bernard ULg; Lemaire, Christian ULg; Cantineau, R. et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1990, June 19), 31

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See detail99mtc-Mibi (Rp-30) to Define the Extent of Myocardial Ischemia and Evaluate Ventricular Function
Larock, M. P.; Cantineau, R.; Legrand, Victor ULg et al

in European Journal of Nuclear Medicine (1990), 16(4-6), 223-30

99mTc-MIBI, a new myocardial perfusion agent, is a technetium labeled isonitrile derivative. We have taken advantage of the physical characteristics of 99mTc to combine at rest, post infarction ... [more ▼]

99mTc-MIBI, a new myocardial perfusion agent, is a technetium labeled isonitrile derivative. We have taken advantage of the physical characteristics of 99mTc to combine at rest, post infarction, ventricular function studies with analysis of perfusion. We have studied at rest and at stress, 22 patients with coronary artery disease selected on the basis of an abnormal coronary angiogram or on the basis of a positive exercise ECG stress test for symptomatic angina. We have also studied, at rest only, 20 patients with a previous myocardial infarction. A comparative thallium planar scintigraphy was obtained for all patients. The sensitivity of 99mTc-MIBI scintigraphy for detecting individual vessel lesions at stress was 88% as compared with 83% for 201Tl. Sensitivity was higher in patients with previous myocardial infarction (93% for the 2 isotopes) than in patients without (85% for 99mTc-MIBI versus 81% for 201Tl). Segmental myocardial correspondence between 99mTc-MIBI and 201Tl was very close (92%). The overall sensitivity for the detection of acute myocardial infarction reached respectively 91% for 99mTc MIBI and 87% for 201Tl. The specificity in the regions corresponding to arteries not involved was excellent for both tracers as we did not observe any false positive result. This is important information but it does not correspond to the specificity to detect coronary artery disease in the overall patient population. The correlation between first pass left ventricular ejection fraction obtained with 99mTc-MIBI and equilibrium left ventricular ejection fraction obtained with 99mTc red cells was excellent (r = 0.96). It was not as good but was still satisfactory for the right ventricle (r = 0.75).(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailDevelopment of a new in vivo tracer of the cerebral pH.
Plenevaux, Alain ULg; Demonceau, G.; Cantineau, R. et al

in Journal of Cerebral Blood Flow & Metabolism (1989), 9S1

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See detailEvaluation of [73Se]PROMOSE as a tracer of the human cerebral pH.
Demonceau, G.; Cantineau, R.; Plenevaux, Alain ULg et al

Poster (1988, October 10)

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See detailA New Route for the Synthesis of [18f]Fluoroaromatic Substituted Amino Acids: No Carrier Added L-P-[18f]Fluorophenylalanine
Lemaire, Christian ULg; Guillaume, M.; Christiaens, Léon ULg et al

in International Journal of Radiation Applications and Instrumentation. Part A : Applied Radiation and Isotopes (1987), 38(12), 1033-8

L-p-[18F]fluorophenylalanine was designed as a potential marker for probing protein synthesis in the human brain by positron emission tomography. This radiotracer has been synthesized using nucleophilic ... [more ▼]

L-p-[18F]fluorophenylalanine was designed as a potential marker for probing protein synthesis in the human brain by positron emission tomography. This radiotracer has been synthesized using nucleophilic displacement of the activated nitro group of p-nitrobenzaldehyde by NCA 18F- obtained from the 18O (p, n) reaction on enriched water. The L-form of the [18F]fluoroamino acid can be separated on an analytical scale chiral column. A typical production run of 22.2 GBq (600 mCi) of 18F obtained after a 10 microA.h bombardment of 18 MeV protons on 99.8% 18O-enriched water leads to a batch of 1.11 GBq (30 mCi) of NCA L-p-[18F]fluorophenylalanine after a total synthesis time of 120 min. [less ▲]

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See detailSpecific uptake of N-isopropyl-p-I-123-iodomphetamine by the adrenal cortex.
Demonceau, G.; Beckers, Albert ULg; Desaive, C. et al

in Nuclear Medicine Communications (1987)

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See detailTwo step synthesis of a new Na channel marker by mild oxidation of tetrodotoxin, monitored by HPLC and coupling of (3)ethylenediamine of high specific radioactivity
Bontemps, J; Grandfils, Christian ULg; Cantineau, R et al

in Archives Internationales de Physiologie et de Biochimie (1984), 92

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