References of "CRIELAARD, Jean-Michel"
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See detailDevelopment and validation of the French version of a tool assessing patient's expectations in lower limb osteoarthritis
NEUPREZ, Audrey ULg; Delcour, JP; Fatemi, F et al

in Journal of Orthopaedics (in press)

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See detailOne injection of platelet-rich plasma associated to a submaximal eccentric protocol to treat chronic jumper's knee
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Bruyère, Olivier ULg et al

in The Journal of sports medicine and physical fitness (in press)

INTRODUCTION: Jumper's knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons ... [more ▼]

INTRODUCTION: Jumper's knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons. METHODS: Twenty patients with chronic upper patellar tendinopathy were enrolled. Assessments were made before infiltration of PRP, and 6 weeks and 3 months after the infiltration, using a 10--point Visual Analogic Scale, clinical examinations with a pressure algometer, algofunctional scores (IKDC and VISA--P), functional assessments (isokinetic and optojump evaluations) and imagery (ultrasounds and MRI). The PRP was obtained with an apheresis system (COM.TEC, Fresenius). Six millilitres of PRP were injected without local anaesthetic. One week after infiltration, patients started a standardised sub--maximal eccentric reeducation. RESULTS: Pain during daily activities significantly decreased with time. During functional evaluation, it decreased as well, but without significant functional improvement. No improvements in the imagery measurements were observed. Younger patients seemed to be more susceptible to have an improvement of pain by the PRP infiltration. CONCLUSION: This study demonstrates that a local infiltration of PRP associated with a submaximal eccentric protocol can improve symptoms of chronic jumper's knee in patients non--responsive to classical conservative treatments. [less ▲]

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See detailEvaluation of the impact of 6-month training by whole body vibration on the risk of falls among nursing home residents, observed over a 12-month period: a single blind, randomized controlled trial.
Buckinx, Fanny ULg; Beaudart, Charlotte ULg; Maquet, Didier ULg et al

in Aging clinical and experimental research (in press)

BACKGROUND: We have previously shown that short sessions of whole body vibration (WBV) were not able to significantly improve fall risk among nursing home residents but some trends towards an improvement ... [more ▼]

BACKGROUND: We have previously shown that short sessions of whole body vibration (WBV) were not able to significantly improve fall risk among nursing home residents but some trends towards an improvement of motor capacity were observed. OBJECTIVE: The objective of the present study was to evaluate the impact of 6-month training by WBV on functional and motor abilities among nursing home residents observed over a 12-month period. METHODS: Patients were randomized into two groups: the WBV group which received three training sessions every week composed of five series of 15 s of vibration at 30 Hz intensity for a period of 6 months and a control group with normal daily life. The impact of this training on the risk of falls was assessed blindly after 6 and 12 months by the Tinetti Test, the "Timed Up and Go" test and a quantitative evaluation of a 10-s walk performed with a tri-axial accelerometer. The occurrence of falls was also observed. RESULTS: 62 elderly healthy volunteers, (47 women and 15 men, mean age 83.2 +/- 7.9 years) were included in this study. There was no significant difference between the two groups regarding the Tinetti test (p = 0.75), the "Timed Up and Go" test (p = 0.19) and the Locometrix(R) test, except for the step length, measured by dual task (p < 0.01). No significant inter-group difference in the frequency of falls was observed during the 12 months of research. A total of 42 falls were recorded during the first 6 months of experimentation: 24 falls in the treated group and 18 in the control group (p = 0.60). During the next 6 months, 19 falls occurred: 8 falls in the treated group and 11 in the control group (p = 0.52). CONCLUSION: This study failed to establish the effectiveness of low doses of WBV, under the conditions used in our study, on functional and motor abilities of institutionalized elderly patients. However, given the positive results of other studies, further investigations, with modified therapeutic protocols, seem necessary to clarify the effects of WBV in the elderly. [less ▲]

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See detailLe point sur l’évaluation de la force des muscles respiratoires
Kellens, Isabelle ULg; Crielaard, Jean-Michel ULg

in Revue Médicale de Liège (in press)

The strength of respiratory muscles is crucial for quality of life, especially for patients with lung or neurological disorders. Several methods can be used to assess them: i.e direct or indirect ... [more ▼]

The strength of respiratory muscles is crucial for quality of life, especially for patients with lung or neurological disorders. Several methods can be used to assess them: i.e direct or indirect, voluntary or involuntary. The conventional spirometry method assesses indirectly the respiratory function by measuring maximum inspiratory and expiratory pressure, which reflects the coordination of all respiratory muscles. Techniques of magnetic and electrical stimulation can detect a specific muscle dysfunction, independently of the patient's motivation, however they are invasive methods as measurements are made in the esophagus and stomach. The voluntary techniques are generally non-invasive and require patient's cooperation. Measures of respiratory muscle strength, coupled to a conventional spirometry, can predict the development of ventilatory support in patients at risk, and may be useful during weaning from mechanical ventilation in intensive care units. [less ▲]

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See detailAdaptation interculturelle et validation du questionnaire VISA-P en français
Oppong-Kyei, Julian; Bruyère, Olivier ULg; Delvaux, François ULg et al

in 7ème Congrès National SFMES & SFTS 2014 (2014, September)

Introduction La tendinopathie patellaire est une affection musculo-squelettique très fréquentes chez le sportif et la plus fréquente au niveau du genou. Elle affecte le plus souvent des disciplines qui ... [more ▼]

Introduction La tendinopathie patellaire est une affection musculo-squelettique très fréquentes chez le sportif et la plus fréquente au niveau du genou. Elle affecte le plus souvent des disciplines qui nécessitent soit des impulsions et des sauts soit un travail important du quadriceps. Le Victorian Institute of Sports Assessment–Patellar (VISA-P) est un questionnaire permettant d’évaluer les symptômes et leurs retentissements sur les activités physiques quotidiennes et sportives de la tendinopathie patellaire (Jumper’s knee). Comme la plus part des questionnaires de ce type, le VISA-P fut originalement développé pour des patients anglophones et n'est donc pas adapté à une population francophone. En conséquence, l'objectif de cette étude sera de traduire, adapter et valider une version française fiable du VISA-P et d'en évaluer ses propriétés psychométriques. Matériel et méthode La traduction et l’adaptation interculturelle du VISA-P ont été réalisées selon les recommandations internationales (Guidelines for the Process of Cross-Cultural Adaptation of Self-Report Measures). Ce processus s'est déroulé en 6 étapes : traductions initiales, synthèse des traductions, traduction de retour vers la langue d’origine, comité expert, test de la version pré-finale et approbation du comité expert. La version française finale obtenue fut ensuite l’objet d’une évaluation de certaines propriétés psychométriques telles que la fidélité test-retest, la cohérence interne, la validité de construit et les effets plancher et plafond. Nonante-deux sujets furent recruté au total afin de tester ces propriétés psychométriques. Trois groupes de sujets furent utilisés pour répondre conjointement aux VISA-P et à un questionnaire supplémentaire, le Medical Outcomes Survey Short Form 36 questionnaire (SF-36) pour la validité de construit : un groupe de sujets pathologiques principalement recrutés parmi les patients du Centre Hospitalier Universitaire de Liège (28), un groupe de sujets asymptomatiques (22) et un groupe de sportifs à risque recrutés dans divers clubs sportif (42). L'ensemble des participants ont été recrutés au sein de la province de Liège. Résultats Aucun sujet ne présenta de grosses difficultés à comprendre le questionnaire suite au test de la version pré-finale. Les différents membres du comité expert se montrèrent satisfait de la version finale et donnèrent donc leur approbation. La moyenne des scores obtenu est de 53 (± 17) pour le groupe pathologique, 99 (± 2) pour le groupe sain et 86 (± 14) pour le groupe à risque. Les corrélations entre le VISA-P et certaines mesures divergentes du SF-36 semblent donner des résultats faibles. Les coefficients de corrélation mesurés entre les scores du VISA-P et les items convergents du SF-36 paraissent être élevés. Aucun effet plancher ou plafond n'a pu être observer lors de l'évaluation des propriétés psychométriques du VISA-P dans le groupe pathologique. Conclusion La version française du VISA-P est donc être un questionnaire compréhensible, fiable et adapté aux patients francophones souffrant d'une tendinopathie patellaire supérieur. [less ▲]

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See detailAdaptation interculturelle et validation du questionnaire VISA-A en français
Oppong-Kyei, Julian; Bruyère, Olivier ULg; Delvaux, François ULg et al

in 7ème Congrès National SFMES & SFTS 2014 (2014, September)

Introduction La tendinopathie d’Achille, dont la discipline athlétique implique une grosse activité de course à pied, représente une source de douleurs et de handicap. Cette pathologie fait actuellement l ... [more ▼]

Introduction La tendinopathie d’Achille, dont la discipline athlétique implique une grosse activité de course à pied, représente une source de douleurs et de handicap. Cette pathologie fait actuellement l'objet de nouvelles découvertes sur le plan de la physiopathologie permettant l'exploration de nouvelles pistes thérapeutiques. Dans le cadre de telles études, des échelles d’évaluation sont utilisées afin d'évaluer des phénomènes subjectifs ou complexes tels la douleur, la qualité de vie, le handicap, etc. Elles sont généralement composées de plusieurs items dont la cotation est combinée en un score global ou des sous scores dimensionnels. La majorité des échelles algo-fonctionnelles sont développés dans des pays anglophones et sont par conséquence uniquement pertinents pour des sujets parlant l’anglais. Ceci est la cas pour le Victorian Institute of Sports Assessment–Achilles (VISA-A), un questionnaire développé dans le but d'évaluer la sévérité des symptômes de la tendinopathie achilléenne. L’intérêt de ce mémoire est donc de valider une version française fiable de ce questionnaire. Matériel et méthode La traduction et l’adaptation interculturelle du VISA-A ont été réalisées selon les recommandations internationales (Guidelines for the Process of Cross-Cultural Adaptation of Self-Report Measures). Ce processus s'est déroulé en 6 étapes : traductions initiales, synthèse des traductions, traduction de retour vers la langue d’origine, comité expert, test de la version pré-finale et approbation du comité expert. La version française finale obtenue fut ensuite l’objet d’une évaluation de certaines propriétés psychométriques telles que la fidélité test-retest, la cohérence interne, la validité de construit et les effets plancher et plafond. Pour ces évaluations, 116 sujets furent recruté et répartis en 3 groupes : un groupe de sujets pathologiques principalement recrutés parmi les patients du Centre Hospitalier Universitaire de Liège (31), un groupe de sujets asymptomatiques (22) et un groupe de sportifs à risque (63). Tous ces sujets durent également répondre à un questionnaire supplémentaire, le Medical Outcomes Survey Short Form 36 questionnaire (SF-36) pour la validité de construit. L'ensemble des participants ont été recrutés au sein de la province de Liège. Résultats Aucun sujets ne présenta de difficultés à comprendre le questionnaire suite au test de la version pré-finale. Les différents membres du comité expert se montrèrent satisfait de la version finale et donnèrent donc leur approbation. La moyenne des scores obtenus dans le groupe pathologique est de 59 (± 18), celle du groupe sain est de 99 (± 1) et celle du groupe à risque est de 94 (± 7). Aucun effet plancher ou plafond n'a pu être observer lors de l'évaluation des propriétés psychométriques du VISA-A (dans le groupe pathologique). Les corrélations entre le VISA-A et certaines mesures divergentes du SF-36 semblent être faibles. Les coefficients de corrélation mesurés entre les scores du VISA-A et les items convergents du SF-36 paraissent être élevé. Conclusion La version française du VISA-A est donc être un questionnaire compréhensible, fiable et adapté aux patients francophones souffrant d'une tendinopathie d'Achille. [less ▲]

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See detailIntérêt d’une seconde infiltration de plasma riche en plaquettes dans le traitement des tendinopathies patellaires ?
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Buhler, Frédéric et al

in 7ème Congrès National SFMES & SFTS 2014 (2014, September)

Introduction : Des études cliniques ont évalué l’effet du plasma riche en plaquettes (PRP) dans le traitement de la tendinopathie patellaire. Même si une seule infiltration peut améliorer les symptômes du ... [more ▼]

Introduction : Des études cliniques ont évalué l’effet du plasma riche en plaquettes (PRP) dans le traitement de la tendinopathie patellaire. Même si une seule infiltration peut améliorer les symptômes du sportif dans cette indication, la majorité des études évaluent les effets de 3 infiltrations successives. Le but de notre étude était donc de comparer l’efficacité d’une et de 2 infiltrations (rapprochées) de PRP dans le cade de tendinopathies patellaires chroniques, rebelles aux traitements conservateurs. Matériel et méthode : Vingt sportifs souffrant de tendinopathie patellaire depuis plus de 3 mois ont été inclus et randomisés en 2 groupes, respectivement 1 ou 2 infiltrations de PRP (15 jours d’intervalle). Le PRP a été obtenu à l’aide d’une machine d’aphérèse permettant d’obtenir une concentration plaquettaire identique pour tous les sujets. Ils ont bénéficié ensuite d’une rééducation excentrique sous-maximale standardisée. Le suivi a été réalisé à l’aide d’une échelle visuelle analogique de la douleur, de scores algo-fonctionnels (IKDC et VISA-P), ainsi qu’un questionnaire « mode de vie » avant l’infiltration, 3 et 12 mois post-infiltration. Résultats: La concentration de PRP employée était la même au sein des 2 groupes (9x106/µL), et ne contenait pas d’érythrocyte ni de leucocyte. Au terme du suivi (1 an), les résultats montrent une amélioration des scores EVA dans les deux groupes et significative pour le groupe 1 (p=0,005). Les scores VISA-P et IKDC ont tous deux augmentés, significativement dans les deux groupes. Un sujet par groupe n’a pas repris d’activité physique tandis 67% ont repris le sport au niveau antérieur dans le groupe 1 et 78% dans le groupe 2. Conclusion: La comparaison entre 1 et 2 infiltrations rapprochées de PRP n’a pas permis de mettre en évidence de différence entre les 2 groupes sur un suivi d’un an. Une seconde infiltration rapprochée ne semble donc pas indiquée pour améliorer l’efficacité de ce traitement. Cependant, un suivi à plus long terme serait nécessaire. De même l’évaluation d’une seconde infiltration plus à distance (3 mois) de la première mériterait d’être explorée. [less ▲]

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See detailPlatelet-rich plasma to treat patellar tendinopathies: a 1 year follow-up.
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Bruyère, Olivier ULg et al

in Clinical Chemistry & Laboratory Medicine (2014, June), 52(Special Suppl), 1285

Background: Jumper’s knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons ... [more ▼]

Background: Jumper’s knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons. Infiltration of Platelet Rich Plasma (PRP) may be considered as a recent therapeutic option for chronic tendinopathies. The aim of the current study is to evaluate the clinical status and the return to sports activities in patients with chronic upper patellar tendinopathies up to 1 year after 1 infiltration of PRP. Methods: Twenty patients with chronic upper patellar tendinopathy were enrolled. Assessments were made before infiltration of PRP, and 6 weeks and 3 months and 1 year after the infiltration, using a 10-point Visual Analogic Scale and algofunctional scores (IKDC and VISA-P). Moreover, they had to answer an information questionnaire concerning their life and sports activities. The PRP was obtained with an apheresis system (COM.TEC, Fresenius). Six millilitres of PRP were injected without local anaesthetic. One week after infiltration, patients started a standardised sub-maximal eccentric reeducation. Results: Pain during daily activities significantly decreased with time. VAS has significantly dropped, IKDC and VISA-P significantly improved over the follow-up of 1 year. Seventy percents of patients reported a favourable evolution with decrease of pain, 15% did never report any improvement and 15% were treated surgically. Seventy percents returned to sports activities, 64,3% without any pain, and 50% of them recovered the same sport level. Younger patients seemed to be more susceptible to have an improvement of pain by the PRP infiltration. Conclusions: This study demonstrates that a local infiltration of PRP associated with a submaximal eccentric protocol can improve, at 1 year, symptoms of chronic jumper’s knee in patients non-responsive to classical conservative treatments. [less ▲]

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See detailNo interest for a second close infiltration of platelet-rich plasma to treat upper patellar tendinopathies
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Buhler, Frédéric et al

in European Journal of Physical and Rehabilitation Medicine (2014, May), 50(Suppl. 1 to No. 3), 21639-002-

Background: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to ... [more ▼]

Background: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to be an effective treatment for this indication, most of the existing studies evaluated the effects of 2 or 3 successive infiltrations. The aim of this study was to evaluate whether 2 infiltrations of PRP proves more effective than a single treatment. Methods: Twenty patients suffering from jumper’s knee for over than 3 months were enrolled into the study and split into two randomized groups (1 or 2 infiltrations of PRP, respectively). The follow-up evaluation consisted of VAS, IKDC and VISA-P scores, along with algometer, isokinetic and ultrasounds evaluations. Results: The concentration of the PRP used for each infiltration was similar in both groups, and contained no red or white cells. Results revealed no difference in treatment efficacy between the groups. Conclusion: The comparison between 1 or 2 infiltrations of PRP did not reveal any difference between the 2 groups after a follow-up period of 3 months. A second closely-timed infiltration of PRP to treat jumper’s knees is not necessary to improve the efficacy of this treatment in the short term. [less ▲]

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See detailOne-year follow-up of platelet-rich plasma to treat chronic upper patellar tendinopathies
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Bruyère, Olivier ULg et al

in European Journal of Physical and Rehabilitation Medicine (2014, May), 50(Suppl. 1 to No. 3), 227250-

Introduction: Infiltration of PRP may be used as a recent therapeutic option for chronic tendinopathies The aim of the current study is to evaluate the clinic and the return to sports activities in ... [more ▼]

Introduction: Infiltration of PRP may be used as a recent therapeutic option for chronic tendinopathies The aim of the current study is to evaluate the clinic and the return to sports activities in patients with chronic upper patellar tendinopathies 1 year after 1 infiltration of PRP. Material and methods: The follow-up of 20 subjects who beneficed from 1 infiltration of PRP was made before infiltration, after 3 months and 1 year after infiltration; it was made as follow: VAS, IKDC and VISA-P scores. Moreover, they had to answer an information questionnaire concerning their life and sports activities. Results: Seventy percents of patients reported a favourable evolution with decrease of pain, 10% did never report any improvement and 20% were treated surgically. Eighty-seven percents returned to sports activities without any pain, and 50% of them recovered the same sport level. VAS has significantly (p<0.0001) dropped, IKDC significantly improved (p=0.0007) and VISA-P also significantly increased (p=0.0087) over the follow-up of 1 year. Discussion: This study confirms that a local injection of PRP coupled with a program of eccentric rehabilitation through a chronic Jumper's knee, improves painful symptoms and the functionality of the subjects’ knee up to a follow-up of 1 year. [less ▲]

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See detailTendinopathies chroniques et Plasma Riche en Plaquettes
KAUX, Jean-François ULg; Drion, Pierre ULg; Croisier, Jean-Louis ULg et al

in Revue Médicale de Liège (2014)

Platelets contain growth factors released during their degranulation following activation. These growth factors promote tissue remodeling, wound healing and angiogenesis. Currently, the clinical effect of ... [more ▼]

Platelets contain growth factors released during their degranulation following activation. These growth factors promote tissue remodeling, wound healing and angiogenesis. Currently, the clinical effect of Platelet-Rich Plasma (PRP) is still discussed or even controversial. Our researches have evaluated the effectiveness of PRP on the healing of animal tendons and human suffering from chronic jumper's knee. [less ▲]

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See detailEccentric training improves tendon biomechanical properties: a rat model
Kaux, Jean-François ULg; Drion, Pierre ULg; Libertiaux, Vincent et al

in British Journal of Sports Medicine (2014, April), 48(7), 155

Background: Even if eccentric exercises appear favourable in primary prevention of tendons lesions and, especially, in secondary prevention after tendinopathy, the biomechanical changes to the tissue are ... [more ▼]

Background: Even if eccentric exercises appear favourable in primary prevention of tendons lesions and, especially, in secondary prevention after tendinopathy, the biomechanical changes to the tissue are not yet clear. Objective: We aimed to better define the biomechanical changes that affect healthy tendon after eccentric and concentric training. Design: Randomised controlled trial. Participants: Eighteen Sprague-Dawley rats of 2 months. Interventions: The six rats in the control group (U) were not subjected to physical exercise. The 12 remaining rats (6 in each group) ran on a treadmill set at a +15° incline for concentric training (C) or a -15° incline for eccentric training (E), at a speed of 17 m/min for 1 h, three times per week for 5 weeks. Main Outcome Measurements: The tricipital, patellar and Achilles tendons were subsequently removed to perform a traction test until rupture, and a histological analysis was performed. Results: There was a significant improvement in the rupture force of the patellar and tricipital tendons between the U and E groups. The tricipital tendons in the control group presented a significantly smaller cross-section than the E- and C-trained groups, but none between E and C groups. No significant difference was observed for the mechanical stress at rupture per surface unit between the three groups for all three tendons. However, a tendency towards improvement these values was observed between the trained and the U groups for the patellar tendon. Histological studies demonstrated the tendency of the development of a greater number of blood vessels and a larger quantity of collagen in the eccentric group. Conclusions: The mechanical properties of tendons in rats improve after specific training, especially following eccentric training. Our results partly explained how mechanical loading, especially in eccentric mode, could improve the tendon structure. [less ▲]

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See detailEccentric training for elbow hypermobility
Kaux, Jean-François ULg; Delvaux, François ULg; Forthomme, Bénédicte ULg et al

in British Journal of Sports Medicine (2014, April), 48(7), 154

Background: Patients with hypermobility suffer from joints problems and chronic pain is the most frequently reported symptom. Objective: Eccentric muscle strengthening could be very important to protect ... [more ▼]

Background: Patients with hypermobility suffer from joints problems and chronic pain is the most frequently reported symptom. Objective: Eccentric muscle strengthening could be very important to protect hypermobile joints. Design: Case report. Patient: A girl (16 y.o.) affected by an Ehler-Danlos syndrome presented pain in the right elbow and the right wrist after a season of tennis. Interventions: Her training consisted of wrist prono-supination and flexion-extension muscle group reinforcement and proprioceptive training. To protect the wrist against excessive load, the eccentric strengthening exercises of prono-supinator and flexor-extensor muscles of elbow and wrist were undertaken gradually, at increasing speeds within a limited range of motion in flexion and extension, on an isokinetic device after an evaluation. She was also given an orthesis restricting the joint range of motion of the wrist. Main outcome measurements: The evaluation was made by isokinetic evaluation, visual analog scale and MOS-SF36 questionnaire before and after training. Results: The patient rapidly noted a decrease in pain and an increase in the stability of her right arm even when playing tennis. Isokinetic evaluation objectified a significant improvement in maximal torque in flexion-extension muscles of the right elbow. She was also given individualized home exercises. Conclusions: The goal of this eccentric training is to avoid hypermobility by using the muscles as a protective brake in the control of joint positioning. Muscles can be reinforced in eccentric mode with starting position at the maximum length of these muscles when unstreched. The exercises can be carried out safely on an isokinetic device, at slow speed and limited range of joint motion to avoid risk of luxation. Thus, in this case report, the eccentric exercises using an isokinetic device were effective to safely reinforce the muscles as a protective brake for joint hypermobility and prevent pain during practicing tennis. [less ▲]

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See detailExuberant inflammatory reaction as a side effect of platelet-rich plasma injection in treating one case of tendinopathy
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; LEONARD, Philippe ULg et al

in Clinical Journal of Sport Medicine (2014), 24(2), 150-152

Platelet-rich plasma (PRP) contains a large quantity of growth factors, which may enhance tendon healing processes. Local infiltration of PRP represents a relatively new treatment for tendinopathies. To ... [more ▼]

Platelet-rich plasma (PRP) contains a large quantity of growth factors, which may enhance tendon healing processes. Local infiltration of PRP represents a relatively new treatment for tendinopathies. To date, no side effects have been reported after infiltration of PRP to treat tendinopathy. We reported a case of exuberant inflammatory reaction after one infiltration of PRP to treat jumper’s knee in a type 1 diabetic patient who was 35 years old. Injections of PRP must be proposed after careful consideration for patients with morbidity risks linked to insulin-dependent diabetes. [less ▲]

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See detailRevue épidémiologique des blessures lors de la pratique du rugby à XV
Kaux, Jean-François ULg; Julia, Marc; Chupin, Marie et al

in Journal de Traumatologie du Sport (2014), 31(1), 49-53

Rugby is an increasingly popular sport. Full contact being a major characteristic of rugby, injuries are not uncommon. The incidence of injury in Rugby Union reaches 30–91 per 1,000 hours of game time ... [more ▼]

Rugby is an increasingly popular sport. Full contact being a major characteristic of rugby, injuries are not uncommon. The incidence of injury in Rugby Union reaches 30–91 per 1,000 hours of game time. This epidemiological review of injuries in rugby players reports their localization, nature, causes, moment of occurrence in matches and seasonal trends as well as the influence of the player’s position, field conditions, and duration of off time after injury. [less ▲]

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See detailLe contrôle moteur lombopelvien du joueur de footbal élite
GROSDENT, Stéphanie ULg; Demoulin, Christophe ULg; Namurois, Guy et al

in Abstarct Book de la 1ère Journée Guy Namurois (2014, February 22)

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See detailLe traitement médical conservateur des tendinopathies du genou
Kaux, Jean-François ULg; BAUVIR, Philippe ULg; Croisier, Jean-Louis ULg et al

in Ortho-Rhumato (2014), 12(1), 31-34

Les traitements «passifs» des tendinopathies sont généralement utilisés de manière empirique pour combattre la douleur mais ne modifient pas la structure histologique du tendon. Par contre, le travail ... [more ▼]

Les traitements «passifs» des tendinopathies sont généralement utilisés de manière empirique pour combattre la douleur mais ne modifient pas la structure histologique du tendon. Par contre, le travail excentrique a pour but de contrecarrer une théorie étiopathogénique proposant une insuffisance de résistance du tendon exposé à des charges externes qui peuvent progressivement entrainer des lésions. Les résultats cliniques suite à cette prise en charge montrent souvent une évolution favorable des douleurs. Les ondes de choc extra-corporelles demeurent une option thérapeutique non-invasives et présentent peu de complications. De plus, elles sont employées avec succès pour traiter des tendinopathies chroniques rebelles aux traitements conservateurs classiques. Le plasma riche en plaquettes (PRP) est obtenu par centrifugation de sang autologue afin d’obtenir une grande concentration plaquettaire dépendant de la technique employée. Malgré la preuve de l’efficacité du PRP sur la régénération tissulaire en laboratoire, il existe actuellement peu de preuves cliniques tangibles concernant le traitement des tendinopathies chroniques. Enfin, d’autres nouvelles options thérapeutiques (patches de dérivés nitrés, infiltrations de polidocanol, d’acide hyaluronique et de cellules souches) sont également abordées. [less ▲]

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See detailVascular Endothelial Growth Factor-111 (VEGF-111) and tendon healing: preliminary results in a rat model of tendon injury
Kaux, Jean-François ULg; Janssen, Lauriane ULg; Drion, Pierre ULg et al

in Muscles, Ligaments and Tendons Journal (2014), 4(1), 25-28

Tendon lesions are among the most frequent musculoskeletal pathologies. Vascular endothelial growth factor (VEGF) is known to regulate angiogenesis. VEGF-111, a biologically active and proteolysis ... [more ▼]

Tendon lesions are among the most frequent musculoskeletal pathologies. Vascular endothelial growth factor (VEGF) is known to regulate angiogenesis. VEGF-111, a biologically active and proteolysis-resistant splice variant of this family, was recently identified. This study aimed at evaluating whether VEGF-111 could have a therapeutic interest in tendon pathologies. Surgical section of one Achilles tendon of rats was performed before a local injection of either saline or VEGF-111. After 5, 15 and 30 days, the Achilles tendons of 10 rats of both groups were sampled and submitted to a biomechanical tensile test. The force necessary to induce tendon rupture was greater for tendons of the VEGF-111 group (p<0.05) while the section areas of the tendons were similar. The mechanical stress was similar at 5 and 15 days in the both groups but was improved for the VEGF-111 group at day 30 (p <0.001). No difference was observed in the mRNA expression of collagen III, tenomodulin and MMP-9. In conclusion, we observed that a local injection of VEGF-111 improves the early phases of the healing process of rat tendons after a surgical section. Further confirmatory experimentations are needed to consolidate our results. [less ▲]

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