References of "Bloch, B"
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See detailACTH silent adenoma shrinking under cabergoline.
Petrossians, Patrick ULg; Ronci, N.; Valdes Socin, Hernan Gonzalo ULg et al

in European Journal of Endocrinology (2001), 144(1), 51-57

OBJECTIVES: The authors present a case report that proposes the use of cabergoline treatment in silent ACTH adenoma, an unusual member of the heterogeneous group of the so-called clinically non ... [more ▼]

OBJECTIVES: The authors present a case report that proposes the use of cabergoline treatment in silent ACTH adenoma, an unusual member of the heterogeneous group of the so-called clinically non-functioning pituitary adenomas. DESIGN: Following the clinical and radiological improvement of a recurrent silent ACTH adenoma in a 77-year-old patient treated with cabergoline (0.5 mg every 2 days for 2 years), in vitro studies of the original tumor were performed. METHODS: The original tumor from the patient was studied by in situ hybridization and dopamine D2 receptor autoradiography. It was compared with four macroprolactinomas and two macroadenomas from patients with Cushing's disease. RESULTS: The D2 receptor mRNA signal of the reported case was intense and of the same order of magnitude as that observed in control prolactinomas. Dopamine D2 receptor autoradiography was twice that of control corticotroph adenomas and was close to that observed in prolactinomas. CONCLUSIONS: This is the first description of an in vivo shrinkage of an ACTH silent adenoma under cabergoline. We demonstrate in vitro, the presence of D2 receptors in the primitive tumor in concentrations similar to those found in control prolactinomas. These results suggest that therapeutic trials with cabergoline might be undertaken in recurring cases of ACTH silent tumors and more generally, non-functioning pituitary adenomas. [less ▲]

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See detailExpression of somatostatin receptor subtypes 2 and 5 in human prolactinomas
Baillet, L.; Ronci, N.; Epelbaum, J. et al

in 81st Annual Meeting of the Endocrine society - Abstract book (1999)

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See detailSomatostatini SSTR2 and dopamine D2 receptors gene expression in Growth hormone-producing pituitary adenomas
Ronci, N.; Tabarin, A.; Beckers, Albert ULg et al

in 78th Endocrine Society Annual Meeting - Abstract book (1997)

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See detailExpression des récepteurs somatostatinergiques SSTR2 et dopaminergiques D2 dans les adénomes somatotropes
Tabarin, A.; Ronci, N.; Carrié, F. et al

in Annales d'Endocrinologie (1997), 58(2),

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See detailSomatostatin SSTR2 and Dopamine D2 receptors gene expression in Growth Hormone-producing pituitary adenomas
Ronci, N.; Tabarin, A.; Beckers, Albert ULg et al

in Annales d'Endocrinologie (1997), 58(1),

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See detailDopamine D2 receptor gene expression in growth hormone-producing pituitary adenomas
Tabarin, A.; Carrié, F.; Ronci, N. et al

in 4th International Pituitary Congress of Endocrinology - Abstract book (1996)

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See detailDopamine D2 receptor gene expression in growth hormone-producing pituitary adenomas
Tabarin, A.; Carrie, F.; Beckers, Albert ULg et al

in 10th international Congress of Endocrinology - Abstract book (1996)

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