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See detailDepression is a heterogeneous condition: A cluster-analysis approach
Wagener, Aurélie ULiege; Baeyens, Céline; Van der Linden, Martial ULiege et al

Poster (2017, March 24)

The heterogeneity of depression (i.e., symptomatology profiles, treatment responsiveness) is more and more evidenced. From a clinical perspective, having a clearer overview of the symptoms’ heterogeneity ... [more ▼]

The heterogeneity of depression (i.e., symptomatology profiles, treatment responsiveness) is more and more evidenced. From a clinical perspective, having a clearer overview of the symptoms’ heterogeneity of depression will help (1) to deeper understand its underlined psychological processes and (2) to tailor clinical treatments (i.e., psychological interventions and/or antidepressant medications). In order to so, an effort to determine subtypes of depression has been developed through a cluster-analysis approach. Andreasen et al. (1980) identified three clusters of depressed patients based on the Schedule for Affective Disorders and Schizophrenia; Schacht et al. (2014) evidenced five clusters based on the Hamilton Depression Rating Scale (i.e., lack of insight, sleep/sexual/somatic, typical MDD, gastrointestinal/weight loss, mild MDD); Hybels et al. (2012) found three clusters of depressive patients based on the Center for Epidemiologic Studies-Depression Scale in community seniors; and Guidi et al. (2011) found two clusters of depressives in medically ill patients based on the Structured Clinical Interview for DSM-IV (i.e., depressed somatizers, irritable/anxious depression). The current study aims at replicating and extending these previous findings in adults presenting depressive symptoms through a cluster-analysis approach. Unlike previous studies, the highlighting of the clusters will be based on the most frequently used assessment of depression, the Beck Depression Inventory-Second Edition (BDI-II). Further, the definition of the clusters will be based on the presence of the depressive symptoms rather than on their severity because symptoms’ severity on the BDI-II can be misrepresentative of the phenomenology of depressive symptoms’ clusters. A sample of 619 adults from community and mental healthcare centers has been recruited. Inclusion criteria were as follows: being a French-speaking adult aged between 18 and 60 years and presenting at least five symptoms on the BDI-II, irrespective of their severity. Data grouping was achieved through a combination of hierarchical (Ward’s method with squared Euclidian distance measurement) and nonhierarchical procedures (K-means cluster analysis), as recommended by recent theoretical trends. A six-cluster solution was evidenced: heavy sleepers (high levels of tiredness, loss of energy and increase of sleep), cognitive depressives (high levels of pessimism, past failures, guilty feelings, self-dislike and worthlessness), affective-somatic depressives (high levels of affective symptoms - loss of interest and pleasure - and somatic symptoms - increase of appetite and sleep, irritability), mild depressives (mild levels of all symptoms), sleepless depressives (high levels of decrease of sleep and tiredness), typical depressives (high levels of all symptoms). Results evidenced the heterogeneity of depressive symptoms, as six different clusters of depressive adults have been found. Two of the clusters identified in the current study are similar to two clusters identified by Schacht et al. (2014) (sleepless depressives are similar to the cluster “sleep/sexual/somatic” because their profile are highly characterized by symptoms related to insomnia and tiredness; mild depressives are similar to the cluster “mild MDD/symptoms” because their profile are characterized by low to average levels on all symptoms). The take-home message of this study is that depression is a heterogeneous condition. Consequently, it is necessary to consider this heterogeneity in order to tailor the psychological intervention. [less ▲]

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See detailLa modification du biais attentionnel dans les troubles anxieux et la dépression : une revue synthétique de la littérature
Blairy, Sylvie ULiege

in Annales Médico-Psychologiques (2017), 175(6), 522-527

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See detailA comparative study of guided vs pure self-treatment for premature ejaculation
Kempeneers, Philippe ULiege; ANDRIANNE, Robert ULiege; Cuddy, Marion et al

in Sexual and Relationship Therapy (2017)

Self-treatments have previously shown some efficacy in treating premature ejaculation (PE). It has been hypothesized that adding professional support to cognitive-behaviour bibliotherapy could improve ... [more ▼]

Self-treatments have previously shown some efficacy in treating premature ejaculation (PE). It has been hypothesized that adding professional support to cognitive-behaviour bibliotherapy could improve self-treatment outcomes. Therefore, the aim of this study was to compare treatment outcomes for participants with PE who used bibliotherapy alone (pure self-treatment) versus those who used the bibliotherapy with brief support from a health professional (guided self-treatment). Health professionals were not experienced sex therapists, but had attended a short training session in order to equip them to support the self-help process. 135 men reporting difficulties with PE were recruited between February and June 2013. Seventy-one (52.59%) completed the protocol: 37 in the pure self-treatment condition, 34 in the guided self-treatment condition. Thirty-five participants (50%) met criteria for ISSM definition of lifelong PE, 14 (20%) for acquired PE, and 22 (30%) presented other forms of PE complaints. At 4-8 months post-treatment, improvements were found in both groups and in each subtype of PE on self-reported measures of sexual functioning and sexual cognitions. Univariate analyses indicated slightly greater treatment effects in the guided self-treatment group, but multivariate tests failed to identify a significant effect of therapist support. These mixed findings raise questions regarding the amount and quality of therapist input used in this study, and also about a possible ceiling effect of cognitive-behaviour therapy for PE. [less ▲]

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See detailDéficits de la conscience autonoétique et de la mémoire autobiographique: résultats d'une intervention cognitive dans la schizophrénie.
Boulanger, Marie ULiege; Neumann, Aurore; Blairy, Sylvie ULiege

in Pratiques Psychologiques (2017)

The study evaluates the effects of a cognitive intervention called Self-Awareness Therapy (SAT) on abilities of mental time travel in deficit in schizophrenia. Among whole schizophrenia participants ... [more ▼]

The study evaluates the effects of a cognitive intervention called Self-Awareness Therapy (SAT) on abilities of mental time travel in deficit in schizophrenia. Among whole schizophrenia participants, seven participated in SAT, four took part in the Integrative Program Therapy (IPT) and six followed a treatment as usual. Before and after interventions, participants were asked to complete TEMPau for autonoetic awareness and autobiographical memory such as TeMA, for autobiographical memory and projection into future events. Intragroups and individual statistical analyses were conducted. The participants of SAT intervention reported more specific past TEMPau and future specific events on TeMA after therapy. Results support that, in schizophrenia, the retrieving of past specific memories and projection into future specific events could be improved under certain conditions only. [less ▲]

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See detailUne vision moderne de la dépression et de son hétérogénéité
Wagener, Aurélie ULiege; Blairy, Sylvie ULiege

in Revue Francophone de Clinique Comportementale et Cognitive (2016), XXI(3),

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See detailL'activation comportementale est-elle pertinente pour tous les adultes dépressifs ? Une analyse en clusters
Wagener, Aurélie ULiege; Baeyens, Céline; Van der Linden, Martial ULiege et al

Poster (2016, November 26)

INTRODUCTION : L’hétérogénéité de la dépression est de plus en plus mise en évidence en termes de profils de symptômes, de réponse au traitement, etc. Les théories comportementales de la dépression ... [more ▼]

INTRODUCTION : L’hétérogénéité de la dépression est de plus en plus mise en évidence en termes de profils de symptômes, de réponse au traitement, etc. Les théories comportementales de la dépression soulignent l’importance de l’inactivité ainsi que des faibles niveaux de plaisir et de fréquence d’activités plaisantes dans le maintien de la dépression. Cette étude poursuit deux objectifs : (1) investiguer l’hétérogénéité de la depression via une analyse en clusters, (2) investiguer les valeurs prédictives de l’inactivité ainsi que des faibles niveaux de plaisir et de fréquence d’activités plaisantes sur la dépression en fonction du cluster d’appartenance. METHODE : Des adultes tout venant et/ou consultant des centres de santé mentale ont été recrutés (âge entre 18 et 60 ans). Ils ont complété l’Inventaire de Dépression de Beck – Seconde Edition, l’Echelle d’Activation Comportementale pour la Dépression – Version courte, et l’Inventaire des événements plaisants. RESULTATS : Une solution en six clusters a été mise en évidence : “gros dormeurs/heavy sleepers”, “dépressifs cognitifs/cognitive depressives”, “dépressifs affectifs-somatiques/affective-somatic depressives”, “dépressifs légers/mild depressives”, “dépressifs dormant peu/sleepless depressives”, “dépressifs typiques/typical depressives”. Des relations significatives entre inactivité, fréquence d’activités plaisantes et dépression ont seulement été observées chez les “dépressifs cognitifs/cognitive depressives”, les “dépressifs légers/mild depressives” et les “dépressifs typiques/typical depressives”. DISCUSSION : Les résultats confirment l’hétérogénéité de la dépression puisque six clusters ont été mis en évidence. Par ailleurs, l’activation comportementale ne semble pertinente que pour trois de ces clusters dans lesquels les postulats du modèle comportemental de la dépression sont confirmés (“dépressifs cognitifs/cognitive depressives”, “dépressifs légers/mild depressives”, “dépressifs typiques/typical depressives”). [less ▲]

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See detailSelf-defining memories and future projections as a means to facilitate reflection on life values in depressed adults: A preliminary study
Wagener, Aurélie ULiege; Brouette, Béatrice ULiege; Blairy, Sylvie ULiege

Poster (2016, September 10)

Introduction. In the Brief Behavioral Activation Treatment for Depression, depressed patients are lead to a reflection on their personal values per life domains (e.g., family relationships, employment ... [more ▼]

Introduction. In the Brief Behavioral Activation Treatment for Depression, depressed patients are lead to a reflection on their personal values per life domains (e.g., family relationships, employment). The aim of this reflection is to tailor behavioral assignments through valued activities. This reflection is usually difficult for depressed patients. The current study hypothesized that exercises on autobiographical memories might act as a means to facilitate the reflection on personal values. In this perspective, self-defining memories (SDMs) and self-defining future projections (SDFPs) appear to be particularly relevant. SDMs and SDFPs concern reflections on the past and on the potential future central goals, values and conflicts of one’s life. SDMs and SDFPs are vivid and well-rehearsed autobiographical memories related to a meaning-making (i.e., a learned lesson about oneself, others or the world). The emotional valence of SDMs and SDFPs can either be positive, neutral or negative. Further, SDMs and SDFPs can consist in either specific events or categorical ones. Due to the relevance of these memories for the self, it is to be expected that recalling SDMs and imagine SDFPs will help individuals to have a clearer view of their personal values which in turn might facilitate the selection of valued activities. Further, it is hypothesized that these exercises might decrease depression and disturbances of psychological processes (i.e., rumination, self-concept clarity, environmental satisfaction). Therefore, this study aims were two-fold. First, it aimed at assessing the feasibility for depressed patients to recall SDMs and to imagine SDFPs per life domains. Second, it aimed at assessing the impact of these exercises on depression and psychological processes. Method. Nineteen depressed patients and 17 paired healthy controls (25-60 years) were recruited (data collection is still ongoing). This study comprises four meetings. During the first and the last meetings, participants completed self-reported assessments of depression and psychological processes. During the third and fourth meetings, participants were asked either to recall SDMs or to imagine SDFPs per life domains. SDMs and SDFPs were rated on specificity, meaning-making and emotional. The impact of these exercises was assessed on depression and psychological processes. Results. Preliminary results indicate that depressed patients are as able as healthy controls to recall SDMs and imagine SDFPs per life domains. Depressed patients recall less SDMs and SDFPs with meaning-making than healthy controls. Depressed patients report less SDMs and less SDFPs related to employment and less SDMs related to hobbies than healthy controls. Preliminary results show a decrease of depression in depressed patients only. Discussion. Even though depressed patients are as able as the healthy controls to recall SDMs and to imagine SDFPs, preliminary results highlight significant differences between depressed patients and healthy controls on SDMs and SDFPs. Preliminary results indicate that SDMs and SDFPs positively impact depression in depressed patients. Experimental and clinical implications of these findings will be discussed during the conference. [less ▲]

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See detailInactivité, procrastination, apathie et manque d'objectifs quotidiens : Un même concept ?
Wagener, Aurélie ULiege; Carré, Arnaud; Bouvard, Martine et al

Conference (2016, June 10)

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See detailImpact d'un programme d'activation comportementale sur l'humeur, le niveau d'engagement dans des activités, les ruminations et les biais attentionnels chez des étudiantes universitaires
Krings, Audrey ULiege; Wagener, Aurélie ULiege; Blairy, Sylvie ULiege

Poster (2016, June)

A Behavioral activation program was proposed to undergraduated students with difficulties to deal with their mood. Six sessions of a Martell's program was proposed with two evaluations, before (T0) and ... [more ▼]

A Behavioral activation program was proposed to undergraduated students with difficulties to deal with their mood. Six sessions of a Martell's program was proposed with two evaluations, before (T0) and after (T1) the sessions. Different psychological processes were evaluated (behavioral activation, avoidance, rumination and attentional biases). Compared to the control group, a significal reduction was observed for abstract rumination, avoidance and a significant enhancement of selective attention to positive faces in the dot probe task was also observed. [less ▲]

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See detail• BibliothEP: a study evaluating the effectiveness of bibliotherapy for premature ejaculation
Kempeneers, Philippe ULiege; Andrianne, Robert ULiege; Bauwens, Sabrina et al

Conference (2016, May 27)

Objective. The BibliothEP study aimed to assess the efficacy of a bibliotherapy for premature ejaculation (PE) Design and method. The study was conducted in two phases. First, a sample of 120 participants ... [more ▼]

Objective. The BibliothEP study aimed to assess the efficacy of a bibliotherapy for premature ejaculation (PE) Design and method. The study was conducted in two phases. First, a sample of 120 participants suffering from PE read a concise cognitive behavioural self-help manual for PE (51 A5 pages including illustrations) and were compared after treatment to 66 waiting list controls. Second, 36 subjects received and read the self-help manual and were compared after treatment to 32 subjects having received the same manual plus a complementary brief guidance (45-90 minutes) from a coach not specialised in sex therapy, but who had been specifically trained to support the bibliotherapy intervention (by attending a 5-hour training module). The main outcome measures were self-determined latency time to ejaculation, feelings of control, sexual satisfaction, PE-related distress and subjective impression of improvement. Results. At 6-month posttreatment, all participants showed significant improvements as compared to waiting list condition. The improvements were maintained at 12 month. They were slightly greater in the case of complementary therapist support. Improvements were demonstrated for all forms of PE, but the intervention appeared to be slightly more effective when the problem was of moderate severity. In all cases, improvements in sexual functioning were accompanied by improvements in sexual cognitions. Conclusions. The cost-effectiveness of the self-help manual makes it a valuable first-line treatment for any form of PE. Moreover, the outcome of the bibliotherapy process might be increased by coaching from a health worker specifically trained to this aim. [less ▲]

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See detailDepressive symptomatology and the influence of the behavioral avoidance and activation: A gender-specific investigation
Wagener, Aurélie ULiege; Baeyens, Céline; Blairy, Sylvie ULiege

in Journal of Affective Disorders (2016), 193

BACKGROUNG: Depression is a highly prevalent disorder which is usually considered as differentially experienced depending on gender. Behavioral theories of depression pinpoint the importance of the ... [more ▼]

BACKGROUNG: Depression is a highly prevalent disorder which is usually considered as differentially experienced depending on gender. Behavioral theories of depression pinpoint the importance of the behavioral avoidance in the maintenance of depression. However, little is known about the specific impact of the behavioral avoidance and activation on each depressive symptom as well as on gender differences on the behavioral features of depression. METHODS: This study’s aim was two-fold: (1) to assess the presence of gender differences on the BDI-II; (2) to investigate the respective predictive value of behavioral avoidance and of behavioral activation on each depressive symptom assessed by the BDI-II depending on gender. Community adults and adults attending mental healthcare composed the sample. RESULTS: Results showed differences in symptomatology profiles depending on gender (e.g. higher scores of sadness, self-criticalness in women, higher scores of past failure and loss of pleasure in men). Behavioral avoidance positively predicted almost all depressive symptoms in women and in men while behavioral activation negatively predicted almost all symptoms in both gender. Nevertheless, the strengths of these relationships were different for some symptoms (e.g. pessimism). LIMITATIONS: The use of self-report instruments; the lack of assessment of causal or precipitating factors of the depressive symptomatology; the higher number of women in the sample. CONCLUSIONS: Results are discussed with respect to previous findings and present clinical implications: (1) to underline the relevance of the combination of gender-specific assessment tools; (2) to highlight the need of tailored psychological intervention. [less ▲]

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See detailBibliothEP : a study evaluating the effectiveness of bibliotherapy for
Kempeneers, Philippe ULiege; Andrianne, Robert ULiege; Bauwens,, Sabrina et al

Poster (2016, February)

Objective. The BibliothEP study aimed to assess the efficacy of a bibliotherapy for premature ejaculation (PE) Design and method. The study was conducted in two phases. First, a sample of 120 participants ... [more ▼]

Objective. The BibliothEP study aimed to assess the efficacy of a bibliotherapy for premature ejaculation (PE) Design and method. The study was conducted in two phases. First, a sample of 120 participants suffering from PE read a concise cognitive behavioural self-help manual for PE (51 A5 pages including illustrations) and were compared after treatment to 66 waiting list controls. Second, 36 subjects received and read the self-help manual and were compared after treatment to 32 subjects having received the same manual plus a complementary brief guidance (45-90 minutes) from a coach not specialised in sex therapy, but who had been specifically trained to support the bibliotherapy intervention (by attending a 5-hour training module). The main outcome measures were selfdetermined latency time to ejaculation, feelings of control, sexual satisfaction, PErelated distress and subjective impression of improvement. Results. At 6-month posttreatment, all participants showed significant improvements as compared to waiting list condition. The improvements were maintained at 12 month. They were slightly greater in the case of complementary therapist support. Improvements were demonstrated for all forms of PE, but the intervention appeared to be slightly more effective when the problem was of moderate severity. In all cases, improvements in sexual functioning were accompanied by improvements in sexual cognitions. Conclusions. The cost-effectiveness of the self-help manual makes it a valuable first-line treatment for any form of PE. Moreover, the outcome of the bibliotherapy process might be increased by coaching from a health worker specifically trained to this aim. [less ▲]

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See detail"Quand voyager mentalement dans le temps est difficile) - Une étude comparative des souvenirs et projections définissant le soi chez des patients dépressifs et des sujets contrôles sains
Wagener, Aurélie ULiege; Thirion, Julie; PITCHOT, William ULiege et al

Poster (2016, January)

INTRODUCTION. Les patients dépressifs présentent des difficultés à effectuer le voyage mental dans le temps, une des fonctions principales de la mémoire autobiographique, c’est-à-dire à se projeter ... [more ▼]

INTRODUCTION. Les patients dépressifs présentent des difficultés à effectuer le voyage mental dans le temps, une des fonctions principales de la mémoire autobiographique, c’est-à-dire à se projeter mentalement dans le passé et le futur. Cette étude s’intéresse à des événements passés et futurs potentiels particuliers qui sont les souvenirs et les projections futures définissant le soi (SDS et PFDS, respectivement). Les SDS et les PFDS sont des événements autobiographiques particuliers hautement pertinents pour l’identité de l’individu et qui l’aident à se définir. Plus précisément, les SDS sont considérés comme une cristallisation des liens entre mémoire et identité. Le premier objectif de cette étude est d’évaluer les caractéristiques de ces SDS et des PFDS (spécificité, intégration, valence émotionnelle, modification de la valence émotionnelle pour les SDS) chez des patients dépressifs, en comparaison à des sujets contrôles sains. Le second objectif est d’évaluer les liens entre les caractéristiques des SDS et des PFDS avec la clarté du concept de soi. HYPOTHÈSES. Les patients dépressifs rapporteront des SDS et des PFDS moins spécifiques, moins intégrés et plus négatifs que les sujets contrôles sains. Ceci sera en lien avec une faible clarté du concept de soi. MÉTHODE. 19 patients dépressifs et 17 sujets contrôles sains appariés (sexe, âge, niveau d’éducation) ont évoqué des SDS et des PFDS en fonction de domaines de vie (ex. : relations familiales, hobbies, emploi/carrière). RÉSULTATS. La récolte des données est toujours en cours. Les résultats préliminaires mettent en évidence que les patients dépressifs évoquent des SDS et des PFDS moins intégrés que les sujets contrôles. Les patients dépressifs rapportent également davantage de séquence de contamination dans le rappel de SDS (la valence de l’événement lorsqu’il s’est déroulé était positive et devient négative lors de l’évocation du souvenir). DISCUSSION. Les résultats obtenus confirment partiellement nos hypothèses. Ces résultats semblent cohérents avec certains biais préalablement observés dans l’évocation de souvenirs autobiographiques tels que le biais de congruence à l’humeur. Les implications cliniques de ces résultats seront discutées. [less ▲]

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See detailComment je traite… L’insomnie chronique par la thérapie comportementale et cognitive
Dethier, Marie ULiege; Blairy, Sylvie ULiege; POIRRIER, Robert ULiege

in Revue Médicale de Liège (2016)

L’insomnie est actuellement traitée majoritairement par la pharmacothérapie. Or la thérapie comportementale et cognitive pour l’insomnie présente une meilleure efficacité à long terme que celle-ci. Dans ... [more ▼]

L’insomnie est actuellement traitée majoritairement par la pharmacothérapie. Or la thérapie comportementale et cognitive pour l’insomnie présente une meilleure efficacité à long terme que celle-ci. Dans cet article nous décrivons les principes de base de ce traitement psychothérapeutique de courte durée. Il s’agit de combiner des méthodes de restriction de sommeil, de contrôle des stimuli en lien avec le sommeil, d’apprentissage de techniques de relaxation, des conseils sur l’hygiène de sommeil et des techniques de thérapie cognitive appliquées aux cognitions envahissants les moments d’insomnie. [less ▲]

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See detailLes souvenirs définissant le soi - Quel est l'intérêt de les aborder dans l’entretien clinique ? - Illustration dans le trouble dépressif majeur
Wagener, Aurélie ULiege; Boulanger, Marie ULiege; Blairy, Sylvie ULiege

Scientific conference (2015, October 16)

Les souvenirs définissant le soi (« Self-Defining Memories ») sont des souvenirs autobiographiques particuliers, conceptualisés comme une cristallisation des liens entre mémoire et identité. Ces souvenirs ... [more ▼]

Les souvenirs définissant le soi (« Self-Defining Memories ») sont des souvenirs autobiographiques particuliers, conceptualisés comme une cristallisation des liens entre mémoire et identité. Ces souvenirs semblent particulièrement intéressants pour la définition que nous avons de nous-mêmes et pour la clarté du concept de soi. Nous définirons ces souvenirs et fourniront quelques exemples issus de notre pratique clinique. Nous présenterons leurs caractéristiques (spécificité, intégration, contenu, valence émotionnelle). Nous évoquerons l'intérêt que nous voyons à aborder ces souvenirs dans l'entretien clinique comme outil servant à aider les patients présentant une faible clarté du concept de soi ou encore des difficultés liées à la définition de soi. Nous présenterons également des pistes de prise en charge concrètes. Sur base des résultats de recherches menées au sein de l'unité de psychologie clinique comportementale et cognitive, nous présenterons les caractéristiques particulières de ces souvenirs chez les patients dépressifs, comparés à des sujets contrôles sains. [less ▲]

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See detailLes souvenirs définissant le soi dans le trouble dépressif majeur unipolaire : Pourquoi les évoquer durant l’entretien clinique ?
Wagener, Aurélie ULiege; Boulanger, Marie ULiege; PITCHOT, William ULiege et al

in Acta Psychiatrica Belgica (2015), 116(2), 27-34

Unipolar depressed patients can experience a loss of sense of self-continuity. Self-defining memories which are particular autobiographical memories may consist in psychological interventions aiming at ... [more ▼]

Unipolar depressed patients can experience a loss of sense of self-continuity. Self-defining memories which are particular autobiographical memories may consist in psychological interventions aiming at reestablishing the sense of self-continuity. Working on self-defining memories may also help dealing with other psychological difficulties. This article presents the self-defining memories, their characteristics and different psychological interventions which aim is to enhance the quality of these memories. [less ▲]

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