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See detailSocioeconomic and psychosocial conditions of parents and cardiovascular risk factors in their children: the Belgian Luxembourg Child Study III.
Guillaume, Michèle ULg; Lapidus, L.; Lambert, A. et al

in Acta Paediatrica (1999), 88(8), 866-73

Socioeconomic and psychosocial handicaps are often associated with disease. There is a large body of information on adults on such relationships, but data are sparse on children. In a cohort of 1028 boys ... [more ▼]

Socioeconomic and psychosocial handicaps are often associated with disease. There is a large body of information on adults on such relationships, but data are sparse on children. In a cohort of 1028 boys and girls, selected at random from school classes in Province de Luxembourg, a mainly rural area of Belgium, these problems were analysed in age strata of 6-8, 8-10, 10-12 years. Participation rate was 71%. Information was collected from questionnaires,. Anthropometric variables, blood pressure and glucose as well as cholesterol, triglycerides and insulin were measured in the children and related to the psychosocial and socioeconomic factors, organized into rural, psychosocial, socioeconomic and alcohol/smoking clusters of observations. Rural: Duration of living in the area of the child and parents correlated with diastolic blood pressure, particularly in boys (p < 0.01). Psychosocial: Housewives (p = 0.002) and their children (p = 0.002) had higher body mass indexes (BMI) than other mothers and their children. Sons of housewives also had higher blood pressure (systolic, p = 0.0007, diastolic, p = 0.007). Socioeconomic: Socioeconomic factors of parents (profession, unemployment) played relatively minor roles. Alcohol/smoking: Alcohol consumption was related to skinfold thickness in boys (p = 0.022), but not in girls. Girls, but not boys, with smoking parents had higher BMI (p=0.014). Multiple regression analyses suggested that psychosocial factors, such as housewives as mothers of large families, may be important for associations with cardiovascular risk factors in their children. There were apparent differences in the findings between girls and boys, suggesting that boys are more vulnerable to the impacts of the factors analysed. [less ▲]

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See detailPhysical activity and cardiovascular risk factors in children. The Belgian Luxembourg Child Study.
Guillaume, Michèle ULg; Lapidus, L.; Bjorntorp, P.

in Obesity Research (1997)

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See detailObesity and nutrition. The Belgian Luxembourg Child Study.
Guillaume, Michèle ULg; Lapidus, L.; Beckers, F. et al

in Obesity Research (1997)

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See detailObesity in children. Environmental and genetic Aspects
Guillaume, Michèle ULg; Bjorntorp, P.

in Hormone and Metabolic Research. Supplement Series (1996), 28

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See detailHigh prevalence of cardiovascular risk factors in children from the Belgian Luxembourg province. The Belgian Luxembourg Child Study.
Guillaume, Michèle ULg; Lapidus, L.; Beckers, F. et al

in American Journal of Epidemiology (1996)

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See detailCardiovascular risk factors in children from the Belgian province of Luxembourg. The Belgian Luxembourg Child Study.
Guillaume, Michèle ULg; Lapidus, L.; Beckers, L. et al

in American Journal of Epidemiology (1996), 144(9), 867-80

The Province of Luxembourg is an area in Belgium with a high prevalence of risk factors for cardiovascular disease and non-insulin-dependent diabetes mellitus among adults. In the present study, children ... [more ▼]

The Province of Luxembourg is an area in Belgium with a high prevalence of risk factors for cardiovascular disease and non-insulin-dependent diabetes mellitus among adults. In the present study, children in the age groups 6-8, 8-10, and 10-12 years were selected at random from school classes (n = 1,028), with a participation rate of 70.3%. Anthropometric factors, blood pressure, and fasting blood glucose, plasma cholesterol, triglyceride, and insulin levels were measured in 1992. All anthropometric and metabolic variables increased with age, except for waist: hip circumference ratio in boys and cholesterol in girls. In the oldest group, girls who had passed menarche were taller and heavier and had greater skinfold, body mass index, insulin, and systolic blood pressure values but lower total cholesterol levels and waist: hip ratios than girls who had not passed menarche. Boys had lower skinfolds and higher waist: hip ratios than girls in all age groups, and were significantly shorter and lighter in the oldest age group. There was no difference in body mass index between the two sexes. Girls had higher triglyceride and insulin levels in the 10- to 12-year age group, lower blood glucose values in the 8-10 and 10-12 age groups, and lower diastolic blood pressures in the 8-10 age group. Obesity, blood glucose, triglycerides, insulin, and blood pressure were highly interrelated. Cholesterol, triglycerides, insulin, and blood pressure values were all among the highest of values previously reported in other studies. The deciles of body mass index above 50 appeared to be particularly elevated, suggesting that obesity, when present, was pronounced in this population of children. These findings suggest an accumulation of genetic susceptibility to cardiovascular disease and non-insulin-dependent diabetes mellitus in this stable, ethnically homogeneous, and rather isolated part of continental Europe. [less ▲]

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See detailFamilial trends of obesity through three generations: the Belgian-Luxembourg child study.
Guillaume, Michèle ULg; Lapidus, L.; Beckers, F. et al

in International Journal of Obesity (1995), 19 Suppl 3

Province de Luxembourg in Belgium is an area with clustering of obesity as well as other risk factors for cardiovascular diseases and non-insulin dependent diabetes mellitus. In this study, obesity was ... [more ▼]

Province de Luxembourg in Belgium is an area with clustering of obesity as well as other risk factors for cardiovascular diseases and non-insulin dependent diabetes mellitus. In this study, obesity was studied in a total of 1028 boys and girls in age-strata 6-8, 8-10, 10-12 years, selected at random from school classes. Participation rate was about 70%. Non-participants did not differ from participants in comparisons of school records of height and weight. Furthermore, information on birth weight, parents' height and weight was collected, as well as reported problems of obesity in grandparents. The results show a high prevalence of pronounced obesity in these children. BMIs were strongly correlated between the children and both parents. Furthermore, grandparents' obesity problems were related to the BMI of parents, and also to obesity indices in the children. Birth weights were related to current BMI of the children (in girls only for the youngest age-group), and to their mothers' BMI. It was concluded that obesity is prevalent in this area and can be traced through three generations, and seems to be discoverable already at birth. Energy intake is high and physical activity level is low in these children. However, statistical analyses suggest that familial factors exert a greater impact than environmental factors on the BMI of the children. These results, as well as the wide-spread, consistent familial clustering of obesity, traceable already at birth, suggest influence of strong genetic traits for obesity in this population. [less ▲]

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See detailInsulin and metabolic abnormalities in children and family history of NIDDM. The Belgian Luxembourg Child Study.
Guillaume, Michèle ULg; Lapidus, L.; Beckers, F. et al

in International Diabetes Epidemiology Group, Official Satellite Symposium of the 15th IDF Congress (1994)

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See detailObesity and the metabolic syndrome in children in Province de Luxembourg, Belgium
Guillaume, Michèle ULg; Lapidus, L.; Beckers, F. et al

in Prog. 7th ICO meeting (1994)

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See detailThe metabolic syndrome in children of Province de Luxembourg Belgium.
Guillaume, Michèle ULg; Lapidus, L.; Beckers, F. et al

in Prog 29th Annual Meeting of the European Diabetes Epidemiology Study Group of the EASD (1994)

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See detailNutrition and cardiovascular risk factors in children. Results from a population study. "TheBelgian Luxembourg Child Study".
Guillaume, Michèle ULg; Lapidus, L.; Beckers, F. et al

in Prog. XV International Congress of Nutrition (1993)

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See detailCardiovascular risk factor pattern in children. Results from a population study. "The Belgian Luxembourg Child Study".
Guillaume, Michèle ULg; Lapidus, L.; Beckers, F. et al

in Prog XV International Diabetes Epidemiology Group meeting (1993)

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See detailObesity and other cardiovascular risk factors in children. Results from a population study. "The Belgian Luxembourg Child Study".
Guillaume, Michèle ULg; Lapidus, L.; Beckers, F. et al

in Prog European meeting of EASO (1993)

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