  Venecurine, an Indole Alkaloid from Curare; ; et al in Phytochemistry (1989), 28(9), 2221-2223 A new quaternary indole alkaloid, venecurine, has been isolated by chromatographic techniques from a curare obtained from the Hoti tribe of Venezuela. Elucidation of its structure is based mainly on 2D ... [more ▼] A new quaternary indole alkaloid, venecurine, has been isolated by chromatographic techniques from a curare obtained from the Hoti tribe of Venezuela. Elucidation of its structure is based mainly on 2D-NMR studies. Concurrently with the structural work, frog bioassays were carried out. The curare and venecurine exhibit the same type of activity that is relatively low as compared with the dimeric curarizing alkaloids.These results may be an indication that the sample of curare investigated was a weak one intended to be used for capturing rather than killing animals. [less ▲] Detailed reference viewed: 11 (0 ULg)Isolation and Purification of Panarine, a Quaternary Alkaloid from a Venezuelian Curare; Angenot, Luc  ; et alin Phytochemistry (1988), 27(12), 4002-4004 High Speed Counter Current Chromatography (HSCCC) has been used to isolate and purify two quaternary alkaloids from a sample of curare prepared by the Panare Indians of Estado Bolivar, Venezuela. One of ... [more ▼] High Speed Counter Current Chromatography (HSCCC) has been used to isolate and purify two quaternary alkaloids from a sample of curare prepared by the Panare Indians of Estado Bolivar, Venezuela. One of the compounds is the known base Macusine B. The other one is a new but related base named panarine. Its structure has been established unequivocally by spectral and X-ray cristallographic analysis. [less ▲] Detailed reference viewed: 29 (0 ULg)A propos des transformations de la strychnine et (à propos des principes actifs) des Strychnos curarisants africainsAngenot, Luc ; ; et alin Journal de Pharmacie de Belgique (1976), 31(5), 509-510 Strychnine is unstable under light in chloroformic solution and is partly transformed in pseudostrychnine, genostrychnine (Nb-oxy-strychnine) and chloromethostrychninium (a quaternary derivative). In ... [more ▼] Strychnine is unstable under light in chloroformic solution and is partly transformed in pseudostrychnine, genostrychnine (Nb-oxy-strychnine) and chloromethostrychninium (a quaternary derivative). In other respects the curarizing activity of African Strychnos (e.g. Strychnos usambarensis) is not due to isostrychnine as erroneously written by TURKOVIC (J.Pharm Belg. 1976, 31, 277-286) but to quaternary alkaloids like C-dihydrotoxiferine, C-curarine, afrocurarine and C-calebassine (cf L.ANGENOT et al. Arch. Intern. Pharmacodyn. Ther. 1975, 215, 246-258). [less ▲] Detailed reference viewed: 28 (3 ULg)La désacétylrétuline extraite du Strychnos variabilisAngenot, Luc ; ; in Phytochemistry (1975), 14 Desacetylretuline has been extracted from the rootbark of Strychnos variabilis collected in Congo (Zaïre). The structure determinatiion was deduced from spectral data (UV,IR, MS, NMR, and CD).It is the ... [more ▼] Desacetylretuline has been extracted from the rootbark of Strychnos variabilis collected in Congo (Zaïre). The structure determinatiion was deduced from spectral data (UV,IR, MS, NMR, and CD).It is the first time that this alkaloid is found in Nature. [less ▲] Detailed reference viewed: 12 (2 ULg)Alcaloïdes des Loganiacées: sur l'isolement de l'harmane à partir du Strychnos usambarensisAngenot, Luc ; ; in Plantes Médicinales et Phytothérapie (1973), 7(1), 33-36 Harman has been isolated for the first time from a species of the Family of Loganiaceae. MS data are provided as well as the list of plants where this product has een previously detected. Detailed reference viewed: 14 (0 ULg) |
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