References of "Billen, Frédéric"
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See detailDetection of Angiostrongylus vasorum in the bronchoalveolar lavage fluid or faeces of coughing and healthy dogs in Belgium.
Canonne-Guibert, Morgane ULg; Roels, Elodie ULg; Caron, Yannick ULg et al

in Proceedings of the 24th Ecvim Meeting, Mainz, Germany - 4-6 September 2014 (2014, September)

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See detailComparison of four cartridge type automated blood gas analysers for arterial blood gas analysis in dogs
Roels, Elodie ULg; Delvaux, François ULg; Farnir, Frédéric ULg et al

in Proceedings of the 23th ECVIM Meeting (2013, September)

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See detailPersistent right aortic arch associated with an aberrant left subclavian artery arising from a patent ductus arteriosus in a puppy
Rizza, Maïlis ULg; Claeys, Stéphanie ULg; Billen, Frédéric ULg et al

Poster (2013, August 31)

PERSISTENT RIGHT AORTIC ARCH ASSOCIATED WITH AN ABERRANT LEFT SUBCLAVIAN ARTERY ARISING FROM A PATENT DUCTUS ARTERIOSUS IN A PUPPY Rizza M.*, Claeys S.**, Billen F.***, Mc Entee K. ***, Bolen G ... [more ▼]

PERSISTENT RIGHT AORTIC ARCH ASSOCIATED WITH AN ABERRANT LEFT SUBCLAVIAN ARTERY ARISING FROM A PATENT DUCTUS ARTERIOSUS IN A PUPPY Rizza M.*, Claeys S.**, Billen F.***, Mc Entee K. ***, Bolen G.* *Diagnostic Imaging Section, **Small Animal Surgery Section, ***Small Animal Internal Medicine Section, Department of Clinical Sciences (Companion Animal and Equides), Faculty of Veterinary Medicine, University of Liege, Belgium. Introduction Vascular anomalies develop during foetal development and single or multiple aberrant vessels can be present. Persistent right aorta arch (PRAA) represents over 90% of described vascular ring anomalies and can be accompanied by a left ligamentum arteriosum or a patent left ductus arteriosus (approximately 10% of patients) that causes oesophageal entrapment and secondary sub-obstruction. Radiography is an effective means of detecting vascular ring anomalies when oesophageal dilation and left-sided tracheal displacement are visible. Computed tomography angiography (CTA) is necessary to confirm the nature and the patency of the vascular anomalies present and to identify which of the identified anomalies is causing the clinical signs. Materials and methods A 3.5-month-old, male French Bulldog was presented for regurgitation and vomiting since weaning. Besides a low body score, physical exam was unremarkable. Hypoglycemia was observed on routine blood analysis. Thoracic radiographs and CTA of the thorax were performed. Results The radiographs revealed severe oesophageal dilation cranial to the base of the heart and a ventral and left-sided tracheal displacement. A congenital oesophageal diverticulum secondary to a vascular anomaly was suspected. CTA showed multiple vascular anomalies. A PRAA was observed. An aberrant right subclavian artery (ARSA) was identified originating from the PRAA next to the brachiocephalic trunk. A patent left-to-right patent ductus arteriosus (PDA) was detected between the aorta and the pulmonary trunk and an aberrant left subclavian artery (ALSA) originated from the PDA. The oesophagus was compressed between the PDA and the trachea and was dilated cranially to this narrowing. Endoscopy revealed severely esophageal distension cranially to an extraluminal stenosis. Surgery was performed to ligate and cut the PDA. Discussion Seven types of vascular ring anomaly are described: types I - III have a PRAA, type IV has a double aortic arch, and types V -VII have a left aortic arch with combinations of persistent right ligamentum arteriosum and right subclavian arteries. In the patient described here, the vascular ring anomalies are a novel variant of the defined types. To the authors’ knowledge, an ALSA originating from a PDA has not been described previously. The severe compression of the oesophagus with severe dilation cranial to the heart was caused by the PDA and was resolved by surgical intervention. In conclusion, CTA is necessary to determine which vascular anomalies are present and to identify which of these anomalies is responsible for the clinical signs. This technique enables accurate pre-operative planning. Pownder S. Scrivani PV. Non-selective computed tomography angiography of a vascular ring anomaly in a dog. J Vet Cardiol. 2008 Dec;10(2):125-8 Henjes CR, Nolte I, Wefstaedt P. Multidetector-row computed tomography of thoracic aortic anomalies in dogs and cats: patent ductus arteriosus and vascular rings. BMC Vet Res. 2011 Sep 23;7:57 [less ▲]

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See detailCytokine and transcription factor expression by Aspergillus fumigatus-stimulated peripheral blood mononuclear cells in dogs with sino-nasal aspergillosis
Vanherberghen, Morgane; Bureau, Fabrice ULg; Peters, I.R. et al

in Veterinary Immunology and Immunopathology (2013), 154(3-4), 111-20

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See detailPotential role of Alternaria and Cladosporium species in canine lymphoplasmacytic rhinitis
Mercier, Elise ULg; Peters, I.R.; Billen, Frédéric ULg et al

in Journal of Small Animal Practice (2013), 54 (4)

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See detailSalmeterol or doxycycline do not inhibit acute bronchospasm and airway inflammation in cats with experimentally-induced asthma
Leemans, J.; Kirschvink, N.; Bernaerts, Frederique ULg et al

in Veterinary Journal (2011)

The objective of this study was to determine if inhaled salmeterol, a long-acting β2-adrenergic agonist, and oral doxycycline, a tetracycline antibiotic displaying matrix metalloproteinase (MMP ... [more ▼]

The objective of this study was to determine if inhaled salmeterol, a long-acting β2-adrenergic agonist, and oral doxycycline, a tetracycline antibiotic displaying matrix metalloproteinase (MMP) inhibitory activity, reduce airway inflammation and obstruction in cats with experimentally-induced asthma. Eight Ascaris suum (AS)-sensitised cats were enrolled in a prospective study in which they underwent four AS-challenges at 1 month intervals. The challenged animals were given no treatment or were treated on 4 consecutive days with either: (1) oral prednisolone (1 mg/kg twice daily), (2) inhaled salmeterol (50 μg twice daily), or (3) oral doxycycline (5 mg/kg twice daily), according to a randomised cross-over design. Inhibition of allergen-induced early (EAR) and late (LAR) asthmatic reactions were assessed by barometric whole-body plethysmography. Cytology and measurement of MMP-2 and -9 activities were carried out on bronchoalveolar lavage fluid (BALF). Although none of the treatments prevented the EAR, prednisolone treatment inhibited the LAR. Relative to untreated cats, the eosinophil percentage and MMP-2 activity in BALF were significantly reduced following prednisolone treatment (P < 0.05). Short-term therapy with either salmeterol or doxycycline had no effect on the EAR or LAR or on airway inflammation. Given the chronic nature of this disease in cats, long-term therapy may be required to produce more favourable functional and clinical outcomes. [less ▲]

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See detailDetection of Alternaria and Cladosporium DNA in nasal mucosa from dogs with idiopathic lymphoplasmacytic rhinitis
Mercier, Elise ULg; Peters, Iain; Billen, Frédéric ULg et al

in Proceedings of the 21st ECVIM-CA congress (2011, September 06)

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See detailCCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs.
Merveille, Anne-Christine ULg; Davis, Erica E; Becker-Heck, Anita et al

in Nature Genetics (2011), 43(1), 72-8

Primary ciliary dyskinesia (PCD) is an inherited disorder characterized by recurrent infections of the upper and lower respiratory tract, reduced fertility in males and situs inversus in about 50% of ... [more ▼]

Primary ciliary dyskinesia (PCD) is an inherited disorder characterized by recurrent infections of the upper and lower respiratory tract, reduced fertility in males and situs inversus in about 50% of affected individuals (Kartagener syndrome). It is caused by motility defects in the respiratory cilia that are responsible for airway clearance, the flagella that propel sperm cells and the nodal monocilia that determine left-right asymmetry. Recessive mutations that cause PCD have been identified in genes encoding components of the outer dynein arms, radial spokes and cytoplasmic pre-assembly factors of axonemal dyneins, but these mutations account for only about 50% of cases of PCD. We exploited the unique properties of dog populations to positionally clone a new PCD gene, CCDC39. We found that loss-of-function mutations in the human ortholog underlie a substantial fraction of PCD cases with axonemal disorganization and abnormal ciliary beating. Functional analyses indicated that CCDC39 localizes to ciliary axonemes and is essential for assembly of inner dynein arms and the dynein regulatory complex. [less ▲]

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See detailPrevalence of the mutation responsible for primary ciliary dyskinesia a large population of European and American old English sheepdogs
Merveille, Anne-Christine ULg; Bataille, G.; Davis, E. et al

in 20th ECVIM Meeting - Toulouse - France - 9-12 septembre 2010 (2010, September)

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See detailComputed Tomographic Features of Choanal Atresia in a Friesian Foal
Van Galen, Gaby ULg; Bolen, Géraldine ULg; Verwilghen, Denis ULg et al

in Journal of Equine Veterinary Science (2010), 30(8), 436-440

A 3 week old Friesian foal colt was presented with a history of respiratory distress since birth. Endoscopy showed obstruction of the right nasal passage to the nasopharynx. Computed tomography (CT) was ... [more ▼]

A 3 week old Friesian foal colt was presented with a history of respiratory distress since birth. Endoscopy showed obstruction of the right nasal passage to the nasopharynx. Computed tomography (CT) was performed to further characterize this unilateral blockage: images showed demonstrated a complete membranous obstruction of the ventral meatus, together with a deviation of the vomer bone to the left. The diagnosis of unilateral choanal atresia was confirmed. This is the first report describing CT features of choanal atresia in a foal. [less ▲]

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See detailL’aspergillose naso-sinusale chez le chien
Billen, Frédéric ULg; Peeters, Dominique ULg; Clercx, Cécile ULg

in Monde Vétérinaire (Le) : European Veterinary Magazine (2010), 107

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See detailEfficacy of intrasinusal administration of bifonazole cream alone or in combination with enilconazole irrigation in canine sino-nasal aspergillosis: 17 cases.
Billen, Frédéric ULg; Guieu, L. V.; Bernaerts, F. et al

in Canadian Veterinary Journal = Revue Vétérinaire Canadienne (2010), 51

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See detailProphylactic effects of omega-3 polyunsaturated fatty acids and luteolin on airway hyperresponsiveness and inflammation in cats with experimentally-induced asthma.
Leemans, Jérôme ULg; Cambier, Carole ULg; Chandler, T. et al

in Veterinary Journal (2010)

The aim of this study was to assess the preventive effects of omega-3 polyunsaturated fatty acids (omega3 PUFA) and luteolin supplementation on allergen-induced inflammation in eight Ascaris suum (AS ... [more ▼]

The aim of this study was to assess the preventive effects of omega-3 polyunsaturated fatty acids (omega3 PUFA) and luteolin supplementation on allergen-induced inflammation in eight Ascaris suum (AS)-sensitised cats. Airway responsiveness (AR) tests were performed and venous blood and bronchoalveolar lavage fluid (BALF) collected before and following a single (AS-stimulated) allergen exposure, as well as at the end of a 4-week treatment period, which was followed by a second AS-challenge. The omega6/omega3 fatty acid ratio in erythrocyte membranes, BALF cytology, AR to carbachol, and BALF lipoxin A(4) (LXA(4)), an endogenous inhibitor of inflammation, were assessed at each time point. Compared to respective unstimulated values, AS-challenged cats exhibited a significant rise in BALF eosinophil percentage and there was a trend to increased BALF total cell counts, increased AR and reduced BALF LXA(4) concentrations. The significant decrease in the blood omega6/omega3 ratio seen after supplementation demonstrated that omega3 PUFA were efficiently absorbed. No changes in BALF cytology were found between untreated and treated AS-stimulated cats, but BALF LXA(4) levels were significantly elevated and AR significantly decreased following supplement intake. The study suggests that omega3-luteolin supplementation may have some beneficial effects on AR through a LXA(4)-dependent pathway in cats with experimentally-induced asthma. [less ▲]

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See detailCorrelation of palpated pulse and invasive arterial blood pressure in dogs.
Gommeren, Kris ULg; Peyron, Clémence ULg; Lacoste-Garanger, Nicolas ULg et al

in Proceedings of the 9th EVECCS Annual meeting (2010)

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