References of "Bicchielli, Dario"
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See detailRecent Applications of Alkene Metathesis in Fine Chemical Synthesis
Bicchielli, Dario ULg; Borguet, Yannick ULg; Delaude, Lionel ULg et al

in Dragutan, Valerian; Demonceau, Albert; Dragutan, Ileana (Eds.) et al Green Metathesis Chemistry (2010)

During the last decade or so, the emergence of the metathesis reaction in organic synthesis has revolutionised the strategies used for the construction of complex molecular structures. Olefin metathesis ... [more ▼]

During the last decade or so, the emergence of the metathesis reaction in organic synthesis has revolutionised the strategies used for the construction of complex molecular structures. Olefin metathesis is indeed particularly suited for the construction of small open-chain molecules and macrocycles using crossmetathesis and ring-closing metathesis, respectively. These reactions serve, inter alia, as key steps in the synthesis of various agrochemicals and pharmaceuticals such as macrocyclic peptides, cyclic sulfonamides, novel macrolides, or insect pheromones. The present chapter is aiming at illustrating the great synthetic potential of metathesis reactions. Shortcomings, such as the control of olefin geometry and the unpredictable effect of substituents on the reacting olefins, will also be addressed. Examples to be presented include epothilones, amphidinolides, spirofungin A, and archazolid. Synthetic approaches involving silicon-tethered ring-closing metathesis, relay ring-closing metathesis, sequential reactions, domino as well as tandem metathesis reactions will also be illustrated. [less ▲]

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See detailMicrowave-Assisted Olefin Metathesis
Nicks, François; Borguet, Yannick ULg; Sauvage, Xavier et al

in Dragutan, Valerian; Demonceau, Albert; Dragutan, Ileana (Eds.) et al Green Metathesis Chemistry (2010)

Since the first reports on the use of microwave irradiation to accelerate organic chemical transformations, a plethora of papers have been published in this field. In most examples, microwave heating has ... [more ▼]

Since the first reports on the use of microwave irradiation to accelerate organic chemical transformations, a plethora of papers have been published in this field. In most examples, microwave heating has been shown to dramatically reduce reaction times, increase product yields, and enhance product purity by reducing unwanted side reactions compared to conventional heating methods. The present contribution aims at illustrating the advantages of this technology in olefin metathesis and, when data are available, at comparing microwave-heated and conventionally heated experiments. [less ▲]

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See detailATRP of Methacrylates Catalysed by Homo- and Heterobimetallic Ruthenium Complexes
Borguet, Yannick ULg; Sauvage, Xavier; Bicchielli, Dario ULg et al

in Matyjaszewski, Krzysztof (Ed.) Controlled/Living Radical Polymerization: Progress in ATRP (2009)

The catalytic activity of a series of ruthenium-based homo- and heterobimetallic complexes was determined by investigating the atom transfer radical polymerisation of methyl methacrylate. The complexes ... [more ▼]

The catalytic activity of a series of ruthenium-based homo- and heterobimetallic complexes was determined by investigating the atom transfer radical polymerisation of methyl methacrylate. The complexes under investigation were [(arene)Ru(µ-Cl)3RuCl(C2H4)-(L)] (L = PCy3 or a N-heterocyclic carbene ligand), [(p-cymene)-Ru(µ-Cl)3RuCl(=C=CHR)(PCy3)] (R = Ph or t-Bu), and [RuCl2-(p-cymene){PCy2(CH2)2(eta5-C5H4)TiX2(eta5-C5H5)}] (X = Cl, F, and OBz). The catalytic activity of a variety of related [(p-cymene)-ClRu(µ-Cl)2Ru(O‚^N)(=CHPh)] complexes (O^N is a Schiff base ligand) is also reported. The results clearly demonstrate that the ligands strongly affect the ability of the resulting ruthenium complexes to favour the occurrence of a well-behaved ATRP. [less ▲]

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See detailMicrowave-Assisted Ruthenium-Catalyzed Reactions
Nicks, Francois ULg; Borguet, Yannick ULg; Delfosse, Sebastien et al

in Australian Journal of Chemistry (2009), 62(3), 184-207

Since the first reports on the use of microwave irradiation to accelerate organic chemical transformations, a plethora of papers has been published in this field. In most examples, microwave heating has ... [more ▼]

Since the first reports on the use of microwave irradiation to accelerate organic chemical transformations, a plethora of papers has been published in this field. In most examples, microwave heating has been shown to dramatically reduce reaction times, increase product yields, and enhance product purity by reducing unwanted side reactions compared with conventional heating methods. The present contribution aims at illustrating the advantages of this technology in homogeneous catalysis by ruthenium complexes and, when data are available, at comparing microwave-heated and conventionally heated experiments. Selected examples refer to olefin metathesis, isomerization reactions, 1,3-dipolar cycloadditions, atom transfer radical reactions, transfer hydrogenation reactions, and H/D exchange reactions. [less ▲]

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See detailATRP of methyl methacrylate and styrene catalysed by homobimetallic ruthenium-vinylidene complexes
Bicchielli, Dario ULg; Borguet, Yannick ULg; Sauvage, Xavier ULg et al

in Polymer Preprints (2008)

Styrene and Me methacrylate were subjected to atom transfer radical polymn. using a homobimetallic ruthenium-vinylidene complex (p-cymene)RuCl2/(PCy3)(styrylidene)RuCl2 as catalyst and Et 2 ... [more ▼]

Styrene and Me methacrylate were subjected to atom transfer radical polymn. using a homobimetallic ruthenium-vinylidene complex (p-cymene)RuCl2/(PCy3)(styrylidene)RuCl2 as catalyst and Et 2-bromoisobutyrate (EBiB), 1-phenylethyl bromide, or CCl4 as initiators (in toluene). The polymns. proceeded in a controlled fashion and the polydispersities were quite narrow. Using (EBiB), an induction period was obsd. The polymn. of styrene ceased after 80% conversion because of the degrdn. of the complex into inactive species. With both monomers and CCl4 as initiator, the mol. wt. of the polymers was lower than the calcd. value, i.e., the initiation efficiency was >1. [less ▲]

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