References of "Audiffren, Michel"
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See detailContribution of four lifelong factors of cognitive reserve on late cognition in normal aging and Parkinson’s disease
Rouillard, Maud; Audiffren, Michel; Albinet, Cédric et al

in Journal of Clinical and Experimental Neuropsychology (2016)

Introduction. Cognitive reserve (CR) was proposed to explain how individual differences in brain function help to cope with the effects of normal aging and neurodegenerative diseases. Education ... [more ▼]

Introduction. Cognitive reserve (CR) was proposed to explain how individual differences in brain function help to cope with the effects of normal aging and neurodegenerative diseases. Education, professional solicitations, engagement in leisure and physical activities across the lifetime are considered as major determinants of this reserve. Method. Using multiple linear regression analyses, we tested separately in healthy elderly and Parkinson's disease (PD) populations to what extent cognitive performance in several domains was explained by (1) any of these four environmental lifespan variables ; (2) demographic and clinical variables (age, gender, depression score and, for the PD group, duration of disease and dopaminergic drugs). We also tested for an interaction, if any, between these lifespan variables and brain pathology indexed by global atrophy measured from high-resolution anatomical magnetic resonance imaging. Results. Age was negatively associated with cognitive performance in the PD group. In healthy elderly participants, we observed significant positive associations between cognitive performance and 1) education, 2) leisure activities, 3) professional solicitation (decisional latitude). Furthermore, participants with greater brain atrophy benefited more from CR. In PD patients, education and professional solicitations contributed to cognitive performance but to a lesser extent than in controls. CR factors modulated the relationship between cognition and brain atrophy only in patients with a slight or moderate brain atrophy. Conclusions. Education is the CR factor that contributed the most to late cognitive functioning in both groups, closely followed by leisure activity in normal aging and professional solicitations in PD. Our results also provide evidence suggesting that the effects of CR does not express similarly in normal aging and PD. From a broader perspective, these results seem to indicate that CR factors the most consistently practiced across lifespan (education and professional solicitation) are those that are the more strongly associated to late cognitive efficiency. [less ▲]

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See detailQuantitative multi-parameter mapping in parkinson’s disease: preliminary results
Rouillard, Maud ULg; D'Ostilio, Kevin ULg; Albinet, Cedric et al

Poster (2014, May)

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See detailAn intervention study on physical activity and cognitive functioning in people with Parkinson’s disease
Rouillard, Maud ULg; Audiffren, Michel; Albinet, Cédric et al

Poster (2013)

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See detailChronic exercise differentially impacts perceptual or motor inhibition as a function of age: a cross-sectional study
Albinet, Cédric; Boucard, Geoffrey; Collette, Fabienne ULg et al

Poster (2013)

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See detailEffects of physical activity on the aging of motor and perceptual inhibition
Albinet, Cédric; Boucard, Geoffrey; Collette, Fabienne ULg et al

in Medicine & Science in Sports & Exercise (2012), 44(5), 544

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See detailEffects of Physical Activity on the Aging of Motor and Perceptual Inhibition
Albinet, Cédric; Boucard, Grégory; Collette, Fabienne ULg et al

Poster (2012)

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See detailLes troubles cognitifs associés au vieillissement normal
Collette, Fabienne ULg; Salmon, Eric ULg; Audiffren, Michel

in Audiffren, Michel; François, Pierre-Henri (Eds.) Créativité, Motivation et Vieillissement. Les science cognitives en débat. (2012)

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