References of "Andreykiv, A"
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See detailNumerical simulation of tissue differentiation around loaded titanium implants in a bone chamber.
Geris, Liesbet ULg; Andreykiv, A.; Van Oosterwyck, H. et al

in Journal of Biomechanics (2004), 37(5), 763-9

The application of a bone chamber provides a controlled environment for the study of tissue differentiation and bone adaptation. The influence of different mechanical and biological factors on the ... [more ▼]

The application of a bone chamber provides a controlled environment for the study of tissue differentiation and bone adaptation. The influence of different mechanical and biological factors on the processes can be measured experimentally. The goal of the present work is to numerically model the process of peri-implant tissue differentiation inside a bone chamber, placed in a rabbit tibia. 2D and 3D models were created of the tissue inside the chamber. A number of loading conditions, corresponding to those applied in the rabbit experiments, were simulated. Fluid velocity and maximal distortional strain were considered as the stimuli that guide the differentiation process of mesenchymal cells into fibroblasts, chondrocytes and osteoblasts. Mesenchymal cells migrate through the chamber from the perforations in the chamber wall. This process is modelled by the diffusion equation. The predicted tissue phenotypes as well as the process of tissue ingrowth into the chamber show a qualitative agreement with the results of the rabbit experiments. Due to the limited number of animal experiments (four) and the observed inter-animal differences, no quantitative comparison could be made. These results however are a strong indication of the feasibility of the implemented theory to predict the mechano-regulation of the differentiation process inside the bone chamber. [less ▲]

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See detailExperimental and numerical study on mechanoregulation of tissue differentiation around a loaded implant in a bone chamber
Van Oosterwyck; Geris, Liesbet ULg; Duyck, Joke et al

in Bischoff, G.; Hein, H.-J. (Eds.) Proceedings of the seventh conference of ESEM (2003)

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See detailNumerical simulations of tissue ingrowth and differentiation around a loaded titanium implant in a bone chamber
Van Oosterwyck, Hans; Geris, Liesbet ULg; Vander Sloten, Jos et al

in Proceedings of the symposium on integrated systems in dental healthcare (2003)

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See detailNumerical simulation of peri-implant tissue differentiation in a bone chamber
Geris, Liesbet ULg; Van Oosterwyck, Hans; Andreykiv, A. et al

in European Cells and Materials (2003), 5(2), 16-17

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