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See detailPhysical forcing and physical/biochemical variability of the Mediterranean Sea: A review of unresolved issues and directions for future research
Malanotte-Rizzoli et al, Paula; Artale, V; Borzelli-Eusebi, G et al

in Ocean Science (2014), 10(3),

This paper is the outcome of a workshop held in Rome in November 2011 on the occasion of the 25th anniversary of the POEM (Physical Oceanography of the Eastern Mediterranean) program. In the workshop ... [more ▼]

This paper is the outcome of a workshop held in Rome in November 2011 on the occasion of the 25th anniversary of the POEM (Physical Oceanography of the Eastern Mediterranean) program. In the workshop discussions, a number of unresolved issues were identified for the physical and biogeochemical properties of the Mediterranean Sea as a whole, i.e., comprising the Western and Eastern sub-basins. Over the successive two years, the related ideas were discussed among the group of scientists who participated in the workshop and who have contributed to the writing of this paper. Three major topics were identified, each of them being the object of a section divided into a number of different sub-sections, each addressing a specific physical, chemical or biological issue: 1. Assessment of basin-wide physical/biochemical properties, of their variability and interactions. 2. Relative importance of external forcing functions (wind stress, heat/moisture fluxes, forcing through straits) vs. internal variability. 3. Shelf/deep sea interactions and exchanges of physical/biogeochemical properties and how they affect the sub-basin circulation and property distribution. Furthermore, a number of unresolved scientific/methodological issues were also identified and are reported in each sub-section after a short discussion of the present knowledge. They represent the collegial consensus of the scientists contributing to the paper. Naturally, the unresolved issues presented here constitute the choice of the authors and therefore they may not be exhaustive and/or complete. The overall goal is to stimulate a broader interdisciplinary discussion among the scientists of the Mediterranean oceanographic community, leading to enhanced collaborative efforts and exciting future discoveries [less ▲]

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See detailIBR and BVD control : the key to successful herd management
Makoschey, B.; Franken, P.; Mars, J. M. H. et al

in Berliner und Munchener Tierarztliche Wochenschrift (2010), 123

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See detailMultisite Observations of delta Scuti Stars 7 Aql and 8 Aql (a New delta Scuti Variable): The Twelfth STEPHI Campaign in 2003
Fox Machado, L.; Michel, Eric; Pérez Hernández, F. et al

in Astronomical Journal (The) (2007), 134

We present an analysis of the pulsation behavior of the delta Scuti stars 7 Aql (HD 174532) and 8 Aql (HD 174589), a new variable star, observed in the framework of the STEPHI XII campaign during 2003 ... [more ▼]

We present an analysis of the pulsation behavior of the delta Scuti stars 7 Aql (HD 174532) and 8 Aql (HD 174589), a new variable star, observed in the framework of the STEPHI XII campaign during 2003 June and July; 183 hr of high-precision photometry were acquired by using four-channel photometers at three sites on three continents during 21 days. The light curves and amplitude spectra were obtained following a classical scheme of multichannel photometry. Observations in different filters were also obtained and analyzed. Six and three frequencies have been unambiguously detected above a 99% confidence level in the range 190-300 muHz and 100-145 muHz in 7 Aql and 8 Aql, respectively. A comparison of observed and theoretical frequencies shows that 7 Aql and 8 Aql may oscillate with p-modes of low radial orders, typical among delta Scuti stars. In terms of radial oscillations the range of 8 Aql goes from n=1 to 3, while for 7 Aql the range spans from n=4 to 7. Nonradial oscillations have to be present in both stars as well. The expected range of excited modes according to a nonadiabatic analysis goes from n=1 to 6 in both stars. [less ▲]

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See detailDistinct behavior of mutant triosephosphate isomerase in hemolysate and in isolated form: molecular basis of enzyme deficiency
Orosz, F.; Olah, J.; Alvarez, M. et al

in Blood (2001), 98(10), 3106-12

In a Hungarian family with severe decrease in triosephosphate isomerase (TPI) activity, 2 germ line-identical but phenotypically differing compound heterozygote brothers inherited 2 independent (Phe240Leu ... [more ▼]

In a Hungarian family with severe decrease in triosephosphate isomerase (TPI) activity, 2 germ line-identical but phenotypically differing compound heterozygote brothers inherited 2 independent (Phe240Leu and Glu145stop codon) mutations. The kinetic, thermodynamic, and associative properties of the recombinant human wild-type and Phe240Leu mutant enzymes were compared with those of TPIs in normal and deficient erythrocyte hemolysates. The specific activity of the recombinant mutant enzyme relative to the wild type was much higher (30%) than expected from the activity (3%) measured in hemolysates. Enhanced attachment of mutant TPI to erythrocyte inside-out vesicles and to microtubules of brain cells was found when the binding was measured with TPIs in hemolysate. In contrast, there was no difference between the binding of the recombinant wild-type and Phe240Leu mutant enzymes. These findings suggest that the missense mutation by itself is not enough to explain the low catalytic activity and "stickiness" of mutant TPI observed in hemolysate. The activity of the mutant TPI is further reduced by its attachment to inside-out vesicles or microtubules. Comparative studies of the hemolysate from a British patient with Glu104Asp homozygosity and with the platelet lysates from the Hungarian family suggest that the microcompartmentation of TPI is not unique for the hemolysates from the Hungarian TPI-deficient brothers. The possible role of cellular components, other than the mutant enzymes, in the distinct behavior of TPI in isolated form versus in hemolysates from the compound heterozygotes and the simple heterozygote family members is discussed. [less ▲]

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