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See detailChanges in the Chemical composition of the atmosphere
Adams, F.; Colin, R. G.; De muer, D. et al

Report (1997)

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See detailDepressed Immune Surveillance against Cancer: Role of Deficient T Cell: Extracellular Matrix Interactions
Gorski, A.; Castronovo, Vincenzo ULg; Stepien-Sopniewska, B. et al

in Cell Adhesion and Communication (1994), 2(3), 225-33

Although T cells infiltrate malignant tumors, the local immune response is usually inefficient and tumors escape destruction. While extracellular matrix proteins strongly costimulate T cell responses in ... [more ▼]

Although T cells infiltrate malignant tumors, the local immune response is usually inefficient and tumors escape destruction. While extracellular matrix proteins strongly costimulate T cell responses in normal individuals, our studies indicate that peripheral blood T cells from cancer patients and tumor infiltrating cells respond poorly or are resistant to stimulative signals mediated by collagen I and IV and fibronectin. Moreover, the adhesive properties of cancer T cells are markedly depressed. Those functional deficiencies are paralleled by variable deficits in integrin and non-integrin T cell receptors for extracellular matrix. Immunotherapy with BCG causes a dramatic but transient increase in T cell: ECM interactions. [less ▲]

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See detailL'ingénieur et son art. Défi de la R&D et défi du marché
Vankerkem, Michel; Claustriaux, Jean-Jacques ULg; et al.

in Gestion 2000 (1994), 4

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See detailIn Vitro and in Vivo Modulation of 5-Hydroxytryptamine-, Thyrotropin-Releasing Hormone- and Calcitonin-Gene Related Peptide-Like Immunoreactivities in Adult Rat Sensory Neurons
Delree, P.; Martin, Didier ULg; Sadzot-Delvaux, Catherine ULg et al

in Neuroscience (1992), 51(2), 401-10

In a previous work we have shown that culturing adult rat dorsal root ganglia neurons modifies their neurotransmitter phenotype in such a way that cultured neurons synthesize transmitters that are not ... [more ▼]

In a previous work we have shown that culturing adult rat dorsal root ganglia neurons modifies their neurotransmitter phenotype in such a way that cultured neurons synthesize transmitters that are not found in situ, while several other transmitters are expressed in a much higher percentage of neurons in culture than in situ [Schoenen J. et al. (1989) J. Neurosci. Res. 22, 473-487]. The aim of the present study was to investigate the origin and the nature of the relevant environmental signals that allow this plasticity to be expressed, focusing on three neurotransmitters: 5-hydroxytryptamine, thyrotropin-releasing hormone and calcitonin-gene related peptide. The main results can be summarized as follows: (1) culturing cells in fetal calf serum or on feeder layers of astrocytes, Schwann cells or fibroblasts partially inhibits the serotoninergic phenotype of dorsal root ganglia neurons; (2) in vivo disconnection of dorsal root ganglia from their spinal targets but not from their peripheral or supraspinal targets induces a significant increase of the percentage of 5-hydroxytryptamine- and thyrotropin-releasing hormone-positive neurons in disconnected ganglia; (3) growth factors such as ciliary neuronotrophic factor or basic fibroblast growth factor but not nerve growth factor repress 5-hydroxytryptamine and calcitonin gene-related peptide immunoreactivity in cultured sensory neurons. In conclusion, neurotransmitter gene expression of adult dorsal root ganglia neurons is controlled by complex influences. Our data suggest that thyrotropin-releasing hormone and 5-hydroxytryptamine gene expression are tonically repressed in vivo by factors originating from the spinal segmental level and that growth factors such as ciliary neurotrophic factor or basic fibroblast growth factor could be potential vectors of this repressing effect. [less ▲]

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See detailRapport d'activité 1990-1991
Claustriaux, Jean-Jacques ULg; et al.

Report (1992)

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See detailCell Surface Receptors in Lymphoid Cells: From Cytochemistry to Molecular Biology and from a Phenotype to a Function
Boniver, Jacques ULg; Courtoy, R.; Schaaf-Lafontaine, Nicole ULg et al

in Progress in Histochemistry and Cytochemistry (1992), 26(1-4), 169-81

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See detailRapport d'activité 1990
Claustriaux, Jean-Jacques ULg; et al.

Report (1991)

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See detailLa gestion des ressources humaines dans les institutions du secteur socio-éducatif
Robert, Jocelyne ULg; et al.

Conference (1990, May 15)

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See detailRapport d'activité du bureau de biométrie 1988-1989
Claustriaux, Jean-Jacques ULg; et al.

Report (1990)

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See detailRapport d'activité du bureau de biométrie 1988
Claustriaux, Jean-Jacques ULg; et al.

Report (1989)

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See detailRapport d'activité du Bureau de Biométrie - 1986-1987
Claustriaux, Jean-Jacques ULg; et al.

Report (1988)

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See detailBureau de Biométrie - Rapport d'activité 1986
Claustriaux, Jean-Jacques ULg; et al.

Report (1987)

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