References of "Verloes, Alain"
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See detailMental Retardation with Blepharo-Naso-Facial Abnormalities and Hand Malformations: A New Syndrome?
Van Maldergem, Lionel ULg; Wetzburger, C.; Verloes, Alain ULg et al

in Clinical Genetics (1992), 41(1), 22-4

A syndrome involving facial abnormalities (telecanthus, epicanthus, broad flattened nose, large inverted W-shaped mouth and malformed ears), malformed extremities (camptodactyly, clinodactyly ... [more ▼]

A syndrome involving facial abnormalities (telecanthus, epicanthus, broad flattened nose, large inverted W-shaped mouth and malformed ears), malformed extremities (camptodactyly, clinodactyly, interdigital webbing and joint hyperlaxity) and mental retardation is described in a girl at birth and at 11 years old. A comparison with Pashayan-Pruzansky syndrome, fetal alcohol syndrome, VATER association, Marden-Walker syndrome and Tel-Hashomer syndrome is discussed. We suggest this patient represents a new malformation syndrome or an extreme phenotypic variant of one of the above-mentioned syndromes. [less ▲]

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See detailCombined 10pter-->P11 and 18pter-->Q11 Trisomy in a 7-Year-Old Child
Lapiere, J. C.; Verloes, Alain ULg; Herens, Christian ULg et al

in Genetic Counseling (Geneva, Switzerland) (1992), 3(3), 155-9

We report a severely mentally retarded, dysmorphic girl aged 7 years with a 47,XX, +der(18), t(10;18)(p11.2;q11.2)mat. The phenotype of our patient is compared with 6 cases of trisomy 10p and 10 cases of ... [more ▼]

We report a severely mentally retarded, dysmorphic girl aged 7 years with a 47,XX, +der(18), t(10;18)(p11.2;q11.2)mat. The phenotype of our patient is compared with 6 cases of trisomy 10p and 10 cases of trisomy 18q- from the literature. The short trisomic segment 10pter-10p11 appears to affect more the phenotype than the trisomic segment 18qter-q11. [less ▲]

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See detailLe dépistage prénatal de la trisomie 21 sur sérum maternel. Mise au point
Koulischer, Lucien ULg; Schoos, Roland ULg; Verloes, Alain ULg et al

in Revue Médicale de Liège (1991), 46(12), 625-32

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See detailPrenatal Diagnosis of Cystic Hygroma and Chorioangioma in the Wolf-Hirschhorn Syndrome
Verloes, Alain ULg; Schaaps, Jean-Pierre ULg; Herens, Christian ULg et al

in Prenatal Diagnosis (1991), 11(2), 129-32

We report the prenatal diagnosis of Wolf-Hirschhorn syndrome (4p-) in a 24-week-old fetus. Echographic features included cystic hygroma, a complex heart defect with right ventricular hypoplasia, and a ... [more ▼]

We report the prenatal diagnosis of Wolf-Hirschhorn syndrome (4p-) in a 24-week-old fetus. Echographic features included cystic hygroma, a complex heart defect with right ventricular hypoplasia, and a large placental chorioangioma. We suggest that chorioangioma may be associated with chromosomal imbalance and that systematic careful morphologic examination of the fetus and karyotyping of any pregnancy in which large chorioangioma is detected is advisable. Jugular lymphatic obstruction sequence has not been reported so far in association with 4p-syndrome. [less ▲]

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See detailBranchial Arch Anomalies in Trisomy 18
Verloes, Alain ULg; Seret, N.; Bernier, V. et al

in Annales de Génétique (1991), 34(1), 22-4

The authors report two newborns and one fetus with trisomy 18, who have severe anomalies of the first branchial arch: extreme microtia with imperforate external meatus in two cases, and hemifacial ... [more ▼]

The authors report two newborns and one fetus with trisomy 18, who have severe anomalies of the first branchial arch: extreme microtia with imperforate external meatus in two cases, and hemifacial microsomia in a third one. Those cases point to the huge phenotypic variability of the trisomy 18. [less ▲]

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See detailFamilial neuronal heterotopias as cerebral palsy. An inherited disorder of brain histogenesis
Misson, Jean-Paul ULg; Verloes, Alain ULg

in European Society of Human Genetics (1991)

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See detailMicrospherophakia-Metaphyseal Dysplasia: A 'New' Dominantly Inherited Bone Dysplasia with Severe Eye Involvement
Verloes, Alain ULg; Van Maldergem, Lionel ULg; de Marneffe, Pierre et al

in Journal of Medical Genetics (1990), 27(7), 467-71

We report a father and son affected by a hitherto unpublished bone dysplasia with moderately severe dwarfism. On initial radiographs, thickening of the diaphyses of the long bones was striking. The small ... [more ▼]

We report a father and son affected by a hitherto unpublished bone dysplasia with moderately severe dwarfism. On initial radiographs, thickening of the diaphyses of the long bones was striking. The small bones of the extremities were almost unaffected. With age, the metaphyseal deformation became more prominent. The epiphyses became irregular and their growth was delayed (particularly the femoral heads). The femoral neck showed an unusual 'lip' on the inner edge. Later, the stubby appearance of the long bones faded and, in adulthood, only enlarged metaphyses and deformed femoral necks persisted. The vertebrae showed moderate deformation with irregular flattening, and narrowing of the spinal canal with a shortened interpedicular distance. The eye defects consisted of high grade myopia, microspherophakia, lens coloboma, lens luxation, and retinal detachment. The name 'microspherophakia-metaphyseal dysplasia' is suggested for this probably autosomal dominant bone dysplasia. [less ▲]

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See detailTrisomy 20q. A New Case and Further Phenotypic Delineation
Herens, Christian ULg; Verloes, Alain ULg; Laloux, Françoise ULg et al

in Clinical Genetics (1990), 37(5), 363-6

The present report concerns the clinical and cytogenetic findings in a liveborn girl with trisomy for the long arm of chromosome 20. She was the unbalanced product of a maternal t(18;20)(q23.2;q13.1 ... [more ▼]

The present report concerns the clinical and cytogenetic findings in a liveborn girl with trisomy for the long arm of chromosome 20. She was the unbalanced product of a maternal t(18;20)(q23.2;q13.1) translocation. Our case is compared to the 3 previous reports of trisomy 20q associated with telomeric translocation. Adenosine deaminase dosage falls in the normal range and confirms the exclusion of the ADA locus from the region extending distally to 20q13.1. [less ▲]

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See detailMosaicism of 46,Xx/47,Xx,+9/47,Xx,+?Mar in the Same Amniotic Fluid with Apparent Loss of One Cell Line after Delivery
Herens, Christian ULg; Pierquin, Geneviève ULg; Verloes, Alain ULg et al

in Prenatal Diagnosis (1989), 9(5), 373-5

A 46,XX;47,XX,+9;47,XX,+?mar karyotype was detected in an amniotic fluid cell culture and confirmed in a subsequent fetal blood sample from a 40-year-old woman. After termination of the pregnancy, none of ... [more ▼]

A 46,XX;47,XX,+9;47,XX,+?mar karyotype was detected in an amniotic fluid cell culture and confirmed in a subsequent fetal blood sample from a 40-year-old woman. After termination of the pregnancy, none of the 186 mitoses obtained from a second blood sample was trisomic for chromosome 9 (p less than 0.001). Selection against cells containing trisomy 9 is postulated to explain the disappearance of the lymphocyte clone. [less ▲]

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See detailRoberts-Sc Phocomelia Syndrome with Exencephaly
Verloes, Alain ULg; Herens, Christian ULg; Van Maldergem, Lionel ULg et al

in Annales de Génétique (1989), 32(3), 169-70

We report a 18 weeks old fetus with the typical limb reduction anomalies of SC phocomelia syndrome, associated with exencephaly and unilateral anophthalmia, a feature previously reported in only 2 cases ... [more ▼]

We report a 18 weeks old fetus with the typical limb reduction anomalies of SC phocomelia syndrome, associated with exencephaly and unilateral anophthalmia, a feature previously reported in only 2 cases of severe Roberts syndrome. This observation brings another argument for lumping both diseases in a unique Roberts-SC phocomelia syndrome. Diagnosis was settled by the observation of premature centromeric splitting. [less ▲]

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See detailChromosome 22 Mosaic Monosomy (46,Xy/45,Xy,-22)
Verloes, Alain ULg; Herens, Christian ULg; Lambotte, C. et al

in Annales de Génétique (1987), 30(3), 178-9

A slightly dysmorphic and mentally defective child with mosaic monosomy 22 is reported. Chromosome 22 is absent in 10.5% of lymphocytes and 8.3% of fibroblasts. This is the second case report of that kind.

Detailed reference viewed: 65 (4 ULg)