References of "Vandenbol, Micheline"
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See detailExpression and purification of the human Tre2 product, a putative Ypt/Rab GTPase activating protein.
Bizimungu, Christelle; Stroobants, Aurore ULg; Tricot, Catherine et al

in Archives Internationales de Physiologie et de Biochimie (2005), 191

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See detailQuantification of Bifidobacterium ssp and Lactobacillus spp in rat fecal samples by real-time PCR
Delroisse, Jean-Marc; Boulvin, Anne-Lise; Parmentier, Isabelle et al

in Archives Internationales de Physiologie et de Biochimie (2005), 191

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See detailExpression of a synthetic gene encoding a Tribolium castaneum carboxylesterase in Pichia pastoris
Delroisse, Jean-Marc; Dannau, Marie; Gilsoul, Jean-Jacques et al

in Protein Expression & Purification (2005), 42(2), 286-294

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See detailEstimation of bioreactor efficiency through structured hydrodynamic modeling case study of a Pichia pastoris fed-batch process.
Delvigne, Frank ULg; El Mejdoub, Thami ULg; Destain, Jacqueline ULg et al

in Applied Biochemistry and Biotechnology (2005), 121-124

In this article, two theories are unified to investigate the effect of hydrodynamics on a specific bioprocess: the network-of-zones (NOZ) hydrodynamic structured modeling approach (developed by several ... [more ▼]

In this article, two theories are unified to investigate the effect of hydrodynamics on a specific bioprocess: the network-of-zones (NOZ) hydrodynamic structured modeling approach (developed by several researchers but applied to only a few bioprocesses) and the effectiveness factor eta approach. Two process scales were investigated (20 and 500 L), and for each, hydrodynamics were quantified using an NOZ validated by homogeneity time measurements. Several impeller combinations inducing quite different hydrodynamics were tested at the 20-L scale. After this step, effectiveness factors were determined for each fermentation run. To achieve this, a perfectly mixed microbial kinetic model was evaluated by using simple Monod kinetics with a fed-batch mass balance. This methodology permitted determination of the effectiveness factor with more accuracy because of the relation with the perfect case deduced from the Monod kinetics. It appeared that for the small scale, eta decreased until reaching a value of approx 0.7 (30% from the ideal case) for the three impeller systems investigated. However, stirring systems that include hydrofoils seemed to maintain higher effectiveness factors during the course of the fermentation. This effect can be attributed to oxygen transfer performance or to homogenization efficiency exhibited by the hydrofoils. To distinguish the oxygen transfer from the homogenization component of the effectiveness factor, these phenomena were analyzed separately. After determining the evolution of etaO2 linked to oxygen transfer for each of the fermentation runs, the NOZ model was employed to quantify substrate gradient appearance. After this step, another effectiveness factor, etamix, related to mixing was defined. Consequently, it is possible to distinguish the relative importance of the mixing effect and oxygen transfer on a given bioprocess. The results have highlighted an important scale effect on the bioprocess that can be analyzed using the NOZ model. [less ▲]

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See detailGenetic Characterization Of The Yeast Pichia Anomala (Strain K), An Antagonist Of Postharvest Diseases Of Apple
Friel, D.; Vandenbol, Micheline ULg; Jijakli, Mohamed ULg

in Journal of Applied Microbiology (2005), 98(3),

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See detailAt Least Two Regions Of The Oncoprotein Tre2 Are Involved In Its Lack Of Gap Activity
Bizimungu, C.; Vandenbol, Micheline ULg

in Biochemical and Biophysical Research Communications (2005), 335(3),

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See detailIsolement de suppresseurs hétérologues extragéniques multi-copies de la double mutation de levure msb3- msb4-
Delroisse, Jean-Marc; Breban, Martine; Burny, Arsène et al

Poster (2003, April)

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See detailExpression dans le double mutant levurien msb3msb4 de 2 gènes humains homologues
Bizimungu, Christelle; Burny, Arsène; Portetelle, Daniel ULg et al

Poster (2003, April)

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See detailExpression In A Rabgap Yeast Mutant Of Two Human Homologues, One Of Which Is An Oncogene
Bizimungu, C.; De Neve, N.; Burny, A. et al

in Biochemical and Biophysical Research Communications (2003), 310(2),

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See detailExpression in an msb3msb4 yeast mutant of 2 human homologues of the yeast MSB3 MSB4 genes: RN-tre and Tre2 oncogene
Bizimungu, Christelle; Burny, Arsène; Portetelle, Daniel ULg et al

Poster (2003)

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