References of "Van der Linden, Martial"
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See detailExploration des troubles attentionnels consécutifs à un traumatisme crânien léger
Marique, Patricia; Catale, Corinne ULg; Closset, Annette et al

in Revue de Neuropsychologie (2001), 11

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See detailDeep dysphasia : Further evidence on the relationship between phonological short-term memory and language processing impairments
Majerus, Steve ULg; Lekeu, Françoise ULg; Van der Linden, Martial ULg et al

in Cognitive Neuropsychology (2001), 18(5), 385-410

We report a cognitive investigation of a case of deep dysphasia appearing in the context of primary progressive aphasia. Over a period of 5 years, patient CO presented progressive difficulties in word ... [more ▼]

We report a cognitive investigation of a case of deep dysphasia appearing in the context of primary progressive aphasia. Over a period of 5 years, patient CO presented progressive difficulties in word finding and in oral comprehension, while nonverbal cognitive functions remained preserved. As in other deep dysphasic patients, CO's repetition performance showed marked imageability and lexicality effects, and semantic paraphasias. The same effects were observed in writing-to-dictation. Regularisation errors occurred in word reading. CO's short-term memory span was less than two words. A cognitive analysis of language processing revealed difficulties in phoneme identification and rhyme judgement, in detecting grammatical class for orally presented words, and in oral and written naming. The interpretation of CO's deep dysphasic symptoms within interactive models of language processing confirmed the importance of a phonological short-term storage impairment as an explanatory factor of deep dysphasia. [less ▲]

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See detailLes troubles des fonctions exécutives dans la maladie d'Alzheimer
Collette, Fabienne ULg; Van der Linden, Martial ULg

in Alzheimer Actualités (2001), (155), 6-9

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See detailExperience-dependent changes in cerebral functional connectivity during human rapid eye movement sleep
Laureys, Steven ULg; Peigneux, Philippe ULg; Phillips, Christophe ULg et al

in Neuroscience (2001), 105(3), 521-525

One function of sleep is hypothesized to be the reprocessing and consolidation of memory traces (Smith, 1995; Gais et al., 2000; McGaugh, 2000; Stickgold et al., 2000). At the cellular level, neuronal ... [more ▼]

One function of sleep is hypothesized to be the reprocessing and consolidation of memory traces (Smith, 1995; Gais et al., 2000; McGaugh, 2000; Stickgold et al., 2000). At the cellular level, neuronal reactivations during post-training sleep in animals have been observed in hippocampal (Wilson and McNaughton, 1994) and cortical (Amzica et al., 1997) neuronal populations. At the systems level, using positron emission tomography, we have recently shown that some brain areas reactivated during rapid-eye-movement sleep in human subjects previously trained on an implicit learning task (a serial reaction time task) (Maquet et al., 2000). These cortical reactivations, located in the left premotor area and bilateral cuneus, were thought to reflect the reprocessing - possibly the consolidation - of memory traces during post-training rapid-eye-movement sleep. Here, the experience-dependent functional connectivity of these brain regions is examined. It is shown that the left premotor cortex is functionally more correlated with the left posterior parietal cortex and bilateral pre-supplementary motor area during rapid-eye-movement sleep of subjects previously trained to the reaction time task compared to rapid-eye-movement sleep of untrained subjects. The increase in functional connectivity during post-training rapid-eye-movement sleep suggests that the brain areas reactivated during post-training rapid-eye-movement sleep participate in the optimization of the network that subtends subject's visuo-motor response. The optimization of this visuo-motor network during sleep could explain the gain in performance observed during the following day. [less ▲]

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See detailDevelopment of a test battery for assessing cognitive functions of elderly patients with Down syndrome
Georges, Michel ULg; Thewis, B.; Van der Linden, Martial ULg et al

in Revue de Neuropsychologie (2001), 11(4), 549-579

Post-mortem studies of Down syndrome (DS) individuals older than 35 years show that almost 100% of them develop the neuropathological symptoms of Alzheimer disease (AD). A test battery designed to assess ... [more ▼]

Post-mortem studies of Down syndrome (DS) individuals older than 35 years show that almost 100% of them develop the neuropathological symptoms of Alzheimer disease (AD). A test battery designed to assess several domains of cognition was administered to a group of 12 DS individuals older than 35 years. It proved sensitive to individual differences and thus appears to be appropriate for the observation of cognitive change linked to age. Statistical analyses do not reveal cognitive changes in the DS subjects after one year time. However qualitative analyses of individual profiles suggest a cognitive decline in one subject. Additionally, in a PET-scan examination, three subjects present a mild decrease in cerebral glucose metabolism similar to that usually observed in AD. An AD diagnostic though remains uncertain at this stage. [less ▲]

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See detailThe relationships between executive dysfunction and frontal hypometabolism in Alzheimer's disease
Collette, Fabienne ULg; Delrue, Gaël ULg; Van der Linden, Martial ULg et al

in Brain & Cognition (2001), 47(1/2), 272-275

A serie of tasks assessing executive functions was administered to patients with Alzheimer's disease and control subjects. Two groups of Alzheimer patients were examined : patients with hypometabolism ... [more ▼]

A serie of tasks assessing executive functions was administered to patients with Alzheimer's disease and control subjects. Two groups of Alzheimer patients were examined : patients with hypometabolism restricted to the posterior (temporal and parietal) cerebral areas and patients with hypometabolism in both posterior and anterior (frontal) cerebral areas. The performance of Alzheimer patients was inferior to control subjects on all executive tasks. However, the two groups of Alzheimer patients did not differ from each other on all tasks except one. These data indicate that frontal lobe hypometabolism is not necessary to produce executive impairment in Alzheimer's disease. Consequently, executive dysfunction could be the consequence of a disconnection process between posterior and anterior cerebral areas; [less ▲]

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See detailFurther investigation of the supervisory attentional system in schizophrenia: Planning, inhibition, and rule abstraction
Marczewski, P.; Van der Linden, Martial ULg; Laroi, Frank ULg

in Cognitive Neuropsychiatry (2001), 6(3), 175-192

Investigated supervisory attentional system (SAS) functions in schizophrenic patients. 15 schizophrenic outpatients (mean age 29.93 yrs) and 15 normal controls matched for age, gender, and educational ... [more ▼]

Investigated supervisory attentional system (SAS) functions in schizophrenic patients. 15 schizophrenic outpatients (mean age 29.93 yrs) and 15 normal controls matched for age, gender, and educational level were compared. Three tasks (Tower of London, Hayling, and Brixton tests) were used to examine 3 executive processes (planning, inhibition, and rule detection). Schizophrenic patients performed significantly worse than normal controls on all 3 tasks. In addition, patients' performances on selected measures of the three tests were correlated, even when age and medication were partialled out. It is concluded that patients are impaired on all SAS functions. The possible role of a general impairment (processing speed or cognitive resources) is discussed [less ▲]

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See detailAssociative recognition and item recognition in amnesia
Bastin, Christine ULg; Van der Linden, Martial ULg; Pirenne, David et al

in Proceedings of the Third International Conference on Memory (2001)

It has been hypothesised that the hippocampal regions are involved specifically in the encoding of associations between different kinds of information and in the recollection process of recognition memory ... [more ▼]

It has been hypothesised that the hippocampal regions are involved specifically in the encoding of associations between different kinds of information and in the recollection process of recognition memory. We examined the performance of two severely amnesic patients (AC and MR) with different kinds of lesions on three associative (one intra-modal and two inter-modal) recognition tasks and two item recognition tasks. AC was impaired on all the tasks, whereas MR was impaired on the associative tasks but had a preserved familiarity-based recognition. Combined with the etiology and the loci of the patients’ lesions, these results support partly the hypothesis. [less ▲]

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See detailMemory for temporal context: Effects of aging and encoding conditions
Bastin, Christine ULg; Van der Linden, Martial ULg; Hogge, Michael

in Proceedings of the XII Conference of the European Society for Cognitive Psychology and XVIII Annual Conference of the British Psychological Society (2001)

Whether the memory for temporal context information is mediated by automatic or controlled processes is a matter of debate. If the coding of temporal context information is automatic, memory for temporal ... [more ▼]

Whether the memory for temporal context information is mediated by automatic or controlled processes is a matter of debate. If the coding of temporal context information is automatic, memory for temporal context should not be affected by intention to learn and aging. In order to address this issue, we administered a list discrimination task to young and older adults in either an incidental or an intentional encoding condition. The results showed that the list discrimination performance of the older adults was inferior to the performance of the young subjects. In addition, both young and older subjects’ discrimination performance did not improve in the intentional encoding condition. These results support the hypotheses that the temporal context of an item is encoded automatically. [less ▲]

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See detailLe vieillissement et les processus de la reconnaissance
Bastin, Christine ULg; Van der Linden, Martial ULg

in Revue de Neuropsychologie (2001), 11

Le but de cette étude était double : d’une part, explorer les effets du vieillissement sur la recollection et la familiarité, et d’autre part, comparer deux procédures permettant de tester la ... [more ▼]

Le but de cette étude était double : d’une part, explorer les effets du vieillissement sur la recollection et la familiarité, et d’autre part, comparer deux procédures permettant de tester la reconnaissance (les procédures de type oui-non et à choix forcé). Nous avons administré un test de reconnaissance oui-non et un test de reconnaissance à choix forcé à 64 sujets jeunes (âge moyen : 21.73  2.36 ans) et à 64 sujets âgés (âge moyen : 64.36  3.03). Le matériel était composé de photos de visages d’hommes non familiers. Lors de la phase de reconnaissance, les sujets devaient préciser pour chaque visage reconnu s’il « se souvenait », « savait » ou « devinait » avoir vu le visage (Gardiner, Java, & Richardson-Klavehn, 1996). Les résultats ont montré un effet du vieillissement sur la proportion d’items correctement reconnus dans la tâche oui-non (F(1,124)=7.72, p<0.01), mais pas dans la tâche à choix forcé (F(1,126)=0.94, p=0.33). Par ailleurs, comparativement aux sujets jeunes, les sujets âgés donnaient moins de réponses « je me souviens » (p<0.01 dans la tâche oui-non et p=0.051 dans la tâche à choix forcé) et plus de réponses « je sais » (p=0.078 dans la tâche oui-non et p<0.0005 dans la tâche à choix forcé). Ces résultats confirment les données d’autres études (par exemple, Parkin et Walter, 1992). En ce qui concerne la contribution de la recollection et de la familiarité selon la procédure de test utilisée, les sujets jeunes avaient tendance à utiliser davantage de réponses « je me souviens » dans la tâche oui-non que dans la tâche à choix forcé (p=0.09). Dans les deux groupes d’âge, il y avait plus de réponses « je sais » et « je devine » dans la tâche à choix forcé que dans la tâche oui-non. Ces résultats semblent indiquer que la contribution des deux processus de la reconnaissance serait influencée par le type de procédure utilisé. [less ▲]

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See detailAging and recognition processes
Bastin, Christine ULg; Van der Linden, Martial ULg; Marczewski, Philippe

in Journal of Cognitive Neuroscience (2001), 13(Supplemental), 68

The aim of our study was twofold : to explore the effect of aging on recollection and familiarity and to compare two procedures for testing recognition (the yes-no and forced choice procedures). We ... [more ▼]

The aim of our study was twofold : to explore the effect of aging on recollection and familiarity and to compare two procedures for testing recognition (the yes-no and forced choice procedures). We administered a yes-no and a forced choice recognition task using unfamiliar faces as material to 32 young subjects (mean age: 23) and 32 older adults (mean age: 64.28). During the recognition phase, participants were asked to classify each recognised item as one that evoked a Remember response, a Know response or a Guess response. The results indicated significant age differences on global performance in the yes-no recognition task, but not in the forced choice task. Moreover, older adults gave less Remember responses and slightly more Know responses than young subjects. Our findings are consistent with previous studies indicating a reduction of recollection with aging. Concerning the contribution of recollection and familiarity to recognition as a function of the test format, participants in each age group used more Remember responses in the yes-no task than in the forced choice task and more Know responses in the forced choice than in the yes-no task. Our results seem to support the assumption that the contribution of recollection and familiarity depends on the type of testing procedure. [less ▲]

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See detailMémoire à court terme et pathologies du langage
Poncelet, Martine ULg; Majerus, Steve ULg; Van der Linden, Martial ULg

in Rééducation Orthophonique (2001), 208

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See detailUne approche cognitive de la démence : Implications pour l'évaluation et la prise en charge des patients déments
Van der Linden, Martial ULg; Collette, Fabienne ULg; Juillerat, Anne-Claude

in Albaret, J. M.; Aubert, E. (Eds.) Vieillissement et psychomotricité (2001)

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See detailExploration de l’effet de simple exposition dans le vieillissement
Willems, Sylvie ULg; Adam, Stéphane ULg; Van der Linden, Martial ULg

in Revue de Neuropsychologie (2000, November 25), 9

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See detailReducing apathy and depressive mood in Alzheimer's disease: A case report
Adam, Stéphane ULg; Van der Linden, Martial ULg; Juillerat, Anne-Claude et al

Conference (2000, September 21)

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