References of "Van der Linden, Martial"
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See detailAttention and normal ageing
Van der Linden, Martial ULg; Collette, Fabienne ULg

in Leclercq, M.; Zimmerman, P. (Eds.) Applied neuropsychology of attention : theory, diagnosis and rehabilitation (2002)

Over the past twenty-five years, a great deal of evidence has been accumulated indicating that advancing age is accompanied by a systematic decline in performance on a wide variety of cognitive tasks ... [more ▼]

Over the past twenty-five years, a great deal of evidence has been accumulated indicating that advancing age is accompanied by a systematic decline in performance on a wide variety of cognitive tasks, both in the laboratory and in everyday life. However, age-related decline is not observed in all situations and older adults may even show a relative advantage in some tasks. [less ▲]

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See detailNeural and cognitive bases of upper limb apraxia in corticobasal degeneration
Peigneux, Philippe ULg; Salmon, Eric ULg; Garraux, Gaëtan ULg et al

in Neurology (2001), 57(7), 1259-1268

OBJECTIVE: To investigate the neural and cognitive bases of upper limb apraxia in corticobasal degeneration (CBD). METHODS: Eighteen patients with CBD underwent a cognitive neuropsychological assessment ... [more ▼]

OBJECTIVE: To investigate the neural and cognitive bases of upper limb apraxia in corticobasal degeneration (CBD). METHODS: Eighteen patients with CBD underwent a cognitive neuropsychological assessment of apraxia and resting [(18)F]-fluorodeoxyglucose PET scanning. Two complementary measures of apraxia were computed for each modality of gesture production. First, a performance score measured error frequency during gesture execution. Second, as a more stringent test of the integrity of the praxis system, the correction score measured the patient's ability to correct his or her errors on a second attempt. For each measure type, a cut-off score for the presence of apraxia was defined with regard to healthy controls. Using each cut-off score, the regional cerebral glucose metabolism of patients with CBD with apraxia (i.e., performing below cut-off score) was compared with that of patients with CBD without apraxia. RESULTS: Mean performance scores were below normal values in all modalities. Anterior cingulate hypometabolism predominated in patients with CBD who performed below the cut-off performance score. At variance, mean correction scores were below normal values for gesture imitation only. Hypometabolism in superior parietal lobule and supplementary motor area characterized patients with CBD who were unable to correct their errors at the same rate as control subjects did. CONCLUSIONS: Distinct neural networks underlie distinct aspects of the upper limb apraxic deficits in CBD. Extending previous findings of gesture production deficits in CBD, the use of complementary measures of apraxic behavior discloses a visuoimitative upper limb apraxia in CBD, underlain by a metabolic decrease in a parietofrontal neural network. [less ▲]

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See detailThe functional anatomy of inhibition processes investigated with the Hayling task
Collette, Fabienne ULg; Van der Linden, Martial ULg; Delfiore, Guy et al

in Neuroimage (2001), 14(2), 258-267

The cortical areas involved in inhibition processes were examined with positron emission tomography (PET). The tasks administered to subjects were an adaptation of the Hayling test. In the first condition ... [more ▼]

The cortical areas involved in inhibition processes were examined with positron emission tomography (PET). The tasks administered to subjects were an adaptation of the Hayling test. In the first condition (response initiation), subjects had to complete sentences with a word clearly suggested by the context, whereas in the second condition (response inhibition), subjects had to produce a word that made no sense in the context of the sentence. Results indicated that the response initiation processes were associated to increases of activity in the left inferior frontal gyrus (BA 45/47), whereas response inhibition processes led to increases in a network of left prefrontal areas, including the middle (BA 9 and BA 10) and inferior (BA 45) frontal areas. [less ▲]

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See detailWord priming in normal aging with a task that circumvent explicit memory contamination
Adam, Stéphane ULg; Gouvars, Sébastien; Van der Linden, Martial ULg

Poster (2001, July 18)

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See detailAge differences, cognitive control, and prefrontal cortex in the process dissociation procedure
Chicherio, Christian; Ludwig, C.; de Ribaupierre, S. et al

Poster (2001, July 18)

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See detailImpaired controlled recollection processes in depression and subjective memory complaints
Jermann, Françoise; Adam, Stéphane ULg; Ceschi, Grazia et al

Poster (2001, July 18)

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See detailContribution of Lexico-Semantic Processes to Verbal Short-Term Memory Tasks: A Pet Activation Study
Collette, Fabienne ULg; Majerus, Steve ULg; Van der Linden, Martial ULg et al

in Memory (2001), 9(4-6), 249-259

Recent studies have demonstrated the intervention of long-term memory processes in verbal STM tasks and several cognitive models have been proposed to explain these effects. A PET study was performed in ... [more ▼]

Recent studies have demonstrated the intervention of long-term memory processes in verbal STM tasks and several cognitive models have been proposed to explain these effects. A PET study was performed in order to determine whether supplementary cerebral areas are involved when subjects have to execute short-term memory tasks for items having representations in long-term memory (in comparison to items without such representations: words vs non-words). Results indicate that verbal STM for words specifically involves the left middle temporal gyrus (BA 21) and temporo-parietal junction (BA 39). These areas can be associated with lexical and semantic processes. These results are in agreement with cognitive models that postulate the simultaneous influence of lexical and semantic long-term representations on verbal STM processes and/or a lexico-semantic buffer. [less ▲]

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See detailInvestigation of phonological abilities and phonological STM in Williams syndrome.
Majerus, Steve ULg; Palmisano, I.; Barisinikov, K. et al

Conference (2001, February)

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See detailElaboration d'une batterie d'évaluation des fonctions cognitives de sujets âgés porteurs d'un syndrome de Down
Georges, M.; Théwis, B.; Van der Linden, Martial ULg et al

in Revue de Neuropsychologie (2001), 11

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See detailAcquisition of a novel vocabulary in an amnesic patient
Van der Linden, Martial ULg; Cornil, Valérie; Meulemans, Thierry ULg et al

in Neurocase : Case Studies in Neuropsychology, Neuropsychiatry & Behavioural Neurology (2001), 7(4), 283-293

This study explored the ability of a severe amnesic patient (AC) to acquire new vocabulary words. We compared AC's knowledge of words entered into the French lexicon during three different periods: before ... [more ▼]

This study explored the ability of a severe amnesic patient (AC) to acquire new vocabulary words. We compared AC's knowledge of words entered into the French lexicon during three different periods: before 1920, between 1965 and 1985, and after 1986 (i.e. after the onset of his amnesia). AC's knowledge was assessed by asking him to give, for each word, its definition (word-definition task), the general domain Io which the word belonged ('domain' task), and to generate a sentence containing the word (sentence-generation task). Finally, we administered a recognition task in which AC had to select, for each word, its correct definition amongst four definitions. For all of these tasks, the results showed that AG's performance was similar to that of four control subjects matched for age, education, and profession. In particular, there was no difference with regard to AC's knowledge of words entered into the language after the onset of his amnesia. Therefore, these results indicate that, despite his profound amnesia, AC was able to learn normally new vocabulary words. More generally, they confirm that, at least is some cases, semantic learning can be spared in amnesia. [less ▲]

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See detailExploration des troubles attentionnels consécutifs à un traumatisme crânien léger
Marique, Patricia; Catale, Corinne ULg; Closset, Annette et al

in Revue de Neuropsychologie (2001), 11

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See detailDeep dysphasia : Further evidence on the relationship between phonological short-term memory and language processing impairments
Majerus, Steve ULg; Lekeu, Françoise ULg; Van der Linden, Martial ULg et al

in Cognitive Neuropsychology (2001), 18(5), 385-410

We report a cognitive investigation of a case of deep dysphasia appearing in the context of primary progressive aphasia. Over a period of 5 years, patient CO presented progressive difficulties in word ... [more ▼]

We report a cognitive investigation of a case of deep dysphasia appearing in the context of primary progressive aphasia. Over a period of 5 years, patient CO presented progressive difficulties in word finding and in oral comprehension, while nonverbal cognitive functions remained preserved. As in other deep dysphasic patients, CO's repetition performance showed marked imageability and lexicality effects, and semantic paraphasias. The same effects were observed in writing-to-dictation. Regularisation errors occurred in word reading. CO's short-term memory span was less than two words. A cognitive analysis of language processing revealed difficulties in phoneme identification and rhyme judgement, in detecting grammatical class for orally presented words, and in oral and written naming. The interpretation of CO's deep dysphasic symptoms within interactive models of language processing confirmed the importance of a phonological short-term storage impairment as an explanatory factor of deep dysphasia. [less ▲]

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See detailLes troubles des fonctions exécutives dans la maladie d'Alzheimer
Collette, Fabienne ULg; Van der Linden, Martial ULg

in Alzheimer Actualités (2001), (155), 6-9

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See detailExperience-dependent changes in cerebral functional connectivity during human rapid eye movement sleep
Laureys, Steven ULg; Peigneux, Philippe ULg; Phillips, Christophe ULg et al

in Neuroscience (2001), 105(3), 521-525

One function of sleep is hypothesized to be the reprocessing and consolidation of memory traces (Smith, 1995; Gais et al., 2000; McGaugh, 2000; Stickgold et al., 2000). At the cellular level, neuronal ... [more ▼]

One function of sleep is hypothesized to be the reprocessing and consolidation of memory traces (Smith, 1995; Gais et al., 2000; McGaugh, 2000; Stickgold et al., 2000). At the cellular level, neuronal reactivations during post-training sleep in animals have been observed in hippocampal (Wilson and McNaughton, 1994) and cortical (Amzica et al., 1997) neuronal populations. At the systems level, using positron emission tomography, we have recently shown that some brain areas reactivated during rapid-eye-movement sleep in human subjects previously trained on an implicit learning task (a serial reaction time task) (Maquet et al., 2000). These cortical reactivations, located in the left premotor area and bilateral cuneus, were thought to reflect the reprocessing - possibly the consolidation - of memory traces during post-training rapid-eye-movement sleep. Here, the experience-dependent functional connectivity of these brain regions is examined. It is shown that the left premotor cortex is functionally more correlated with the left posterior parietal cortex and bilateral pre-supplementary motor area during rapid-eye-movement sleep of subjects previously trained to the reaction time task compared to rapid-eye-movement sleep of untrained subjects. The increase in functional connectivity during post-training rapid-eye-movement sleep suggests that the brain areas reactivated during post-training rapid-eye-movement sleep participate in the optimization of the network that subtends subject's visuo-motor response. The optimization of this visuo-motor network during sleep could explain the gain in performance observed during the following day. [less ▲]

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