References of "Van der Linden, Martial"
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See detailProcessus attentionnels et vieillissement normal
Adam, Stéphane ULg; Van der Linden, Martial ULg; Collette, Fabienne ULg

in Couillet, Josettte; Leclerq, Michel; Moroni, Christine (Eds.) et al Neuropsychologie de l'attention (2002)

De très nombreuses études ont mis en évidence une diminution de performance des sujets âgés dans une grande variété de tâches cognitives, à la fois en condition de laboratoire et dans la vie réelle ... [more ▼]

De très nombreuses études ont mis en évidence une diminution de performance des sujets âgés dans une grande variété de tâches cognitives, à la fois en condition de laboratoire et dans la vie réelle. Cependant, ce déclin lié à l'âge n'est pas observé dans toutes les situations et les personnes âgées peuvent même présenter dans certaines tâches des performances supérieures à celles des sujets jeunes. [less ▲]

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See detailEffet de Simple exposition et reconnaissance pour des objets tridimensionnels chez des enfants âgés de 5 à 12 ans et des jeunes adultes
Catale, Corinne ULg; Willems, Sylvie ULg; Van der Linden, Martial ULg

Poster (2002)

Introduction Chez l’adulte, il est classiquement observé que l’exposition répétée à des stimuli conduit à un accroissement de la préférence pour ces derniers en comparaison à de nouveaux stimuli (Effet de ... [more ▼]

Introduction Chez l’adulte, il est classiquement observé que l’exposition répétée à des stimuli conduit à un accroissement de la préférence pour ces derniers en comparaison à de nouveaux stimuli (Effet de simple exposition, ESE; [1]). En revanche, un grand nombre d’études [2] montrent chez l’enfant un effet inverse suggérant une préférence pour la nouveauté. Le but de cette étude est d’utiliser le paradigme de simple exposition chez des enfants de différentes tranches d’âge afin de déterminer la période durant laquelle la préférence pour la nouveauté s’inverse et est remplacée par la préférence pour la familiarité. Participant 16 enfants (de 5 à 6 ans et de 7 à 8 ans), 22 enfants (de 9 à 10 ans), et 17 enfants (de 11 à 12 ans) et 16 jeunes adultes (de 18 à 30 ans). Matériel Dans la phase d’encodage, les sujets évaluent l’orientation (droite/gauche) de 12 figures tridimensionnelles présentées 5 fois durant 2,5 secondes. Lors de la phase test, le sujet est soumis à deux tâches de jugement à choix forcés (préférence et reconnaissance) sur 12 paires d’objets tridimensionnels nouveaux-familiers. Les deux jugements se portent sur les mêmes items et leur ordre de passation est contrebalancés entre les sujets. Résultats et Discussion Un effet de préférence différent du hasard est observé chez les adultes (P<.05) dans le sens d’une préférence pour les stimuli préalablement exposés (ESE), mais non chez les enfants (Ps>.1). Pourtant, lorsque l’on examine les relations entre préférence et reconnaissance, on constate que les enfants de 5/6 ans ont tendance à préférer les nouvelles figures et non les figures préalablement exposées et reconnues (Chi-carré= -.15, p=.05). En revanche, cette tendance s’inverse au cours du développement, et ce, dès 11/12 ans où les enfants tendent à préférer les stimuli préalablement exposés et reconnus (Chi-carré=.17, p=.02). Ce choix de préférence pour les stimuli familiers persistent chez les jeunes adultes (p<.05). Notre étude montre que les plus jeunes enfants ont tendance à préférer les nouveaux stimuli alors que les jeunes adultes préfèrent les stimuli familiers quand on compare leurs choix de préférence à leur performance en reconnaissance. A partir de 11-12 ans, les enfants montrent le pattern inverse indiquant un « shifting » de la préférence pour la nouveauté vers la préférence pour la familiarité. Ces données montrent que les scores en reconnaissance influencent différemment la préférence en fonction de l’âge. [less ▲]

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See detailImplicit learning abilities of amnesic patients
Meulemans, Thierry ULg; Van der Linden, Martial ULg

in French, R. (Ed.) Implicit learning (2002)

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See detailEffects of incidental and intentional feature binding on recognition: a behavioural and PET activation study
Lekeu, Françoise ULg; Van der Linden, Martial ULg; Collette, Fabienne ULg et al

in Neuropsychologia (2002), 40(2), 131-144

Using Positron Emission Tomography (PET), we investigated cerebral regions associated with the episodic recognition of words alone and words bound to contextual colours. Two modes of colour encoding were ... [more ▼]

Using Positron Emission Tomography (PET), we investigated cerebral regions associated with the episodic recognition of words alone and words bound to contextual colours. Two modes of colour encoding were tested: incidental and intentional word-to-colour binding. Word-only recognition was associated with brain activation in a lexico-semantic left middle temporal region and in the cerebellum following an incidental colour encoding, and with brain activation in the left posterior middle frontal gyrus, right anterior cingulate and right inferior frontal gyrus following an intentional encoding. Recognition of bound features was associated with activation in left prefrontal and superior parietal regions following an incidental colour encoding, and with preferential right prefrontal cortex activation following an intentional colour encoding. Our results are in line with the hypothesis of a parietal involvement in context processing, and prefrontal areas in monitoring retrieval processes. Our results also support the hypothesis of a 'cortical asymmetry for reflective activity' (CARA). [less ▲]

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See detailFrontal hypometabolism does not explain inhibitory dysfunction in Alzheimer disease
Collette, Fabienne ULg; Van der Linden, Martial ULg; Delrue, Gaël ULg et al

in Alzheimer Disease and Associated Disorders (2002), 16(4, Oct-Dec), 228-238

A series of tasks assessing inhibitory processes was administered to patients with Alzheimer disease and control subjects. Two groups of patients with Alzheimer disease were examined: patients with ... [more ▼]

A series of tasks assessing inhibitory processes was administered to patients with Alzheimer disease and control subjects. Two groups of patients with Alzheimer disease were examined: patients with hypometabolism restricted to the posterior (temporal and parietal) cerebral areas and patients with hypometabolism in both posterior and anterior (frontal) cerebral areas. The performances of the patients with Alzheimer disease were inferior to those of control subjects on all inhibitory tasks, but the two groups of patients obtained similar scores. These data indicate that frontal lobe hypometabolism is not necessary to produce inhibitory impairment in Alzheimer disease. Consequently, inhibitory dysfunction could be the consequence of a (partial) disconnection process between posterior and anterior cerebral areas. [less ▲]

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See detailAttention et mémoire de travail
Van der Linden, Martial ULg; Collette, Fabienne ULg

in Couillet, J.; Leclerq, M.; Moroni, C. (Eds.) et al La neuropsychologie de l'attention (2002)

Les concepts d'attention et de mémoire de travail ont très souvent été considérés de façon distincte, que ce soit dans le domaine de la recherche ou dans celui de la pratique clinique en neuropsychologie ... [more ▼]

Les concepts d'attention et de mémoire de travail ont très souvent été considérés de façon distincte, que ce soit dans le domaine de la recherche ou dans celui de la pratique clinique en neuropsychologie. Or, une analyse détaillée des modèles théoriques de l'attention et de la mémoire de travail indique au contraire qu'il existe un large recouvrement entre ces deux domaines. L'objectif de ce chapitre est de mettre en exergue ces relations et recouvrements. Plus spécifiquement, nous montrerons en quoi la mémoire de travail a une fonction essentielle de contrôle attentionnel de l'action, nous décrirons les études d'imagerie fonctionnelle ayant exploré les bases cérébrales de cette fonction de contrôle attentionnel et nous présenterons enfin quelques travaux ayant mis en évidence une relation spécifique entre mémoire de travail, attention sélective et vigilance. [less ▲]

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See detailInhibition et lobes frontaux
Le Gall, Didier; Van der Linden, Martial ULg; Andrès Bénito, Pilar et al

in Boujon, C. (Ed.) L'inhibition au carrefour des neurosciences et des sciences de la cognition : fonctionnements normal et pathologique (2002)

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See detailArtificial grammar learning and amnesia
Meulemans, Thierry ULg; Van der Linden, Martial ULg

in French, Robert; Cleeremans, Axel (Eds.) Implicit learning and consciousness : an empirical, philosophical, and computational consensus in the making (2002)

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See detailPreserved familiarity-based recognition memory in a case of global amnesia
Bastin, Christine ULg; Van der Linden, Martial ULg; Charnallet, Annik et al

in Journal of Cognitive Neuroscience (2002), 14(Supplemental), 32

Whether recognition memory can be preserved relative to recall in global amnesia is a matter of debate. Some studies suggest that amnesic patients with selective lesion to the hippocampal circuit show a ... [more ▼]

Whether recognition memory can be preserved relative to recall in global amnesia is a matter of debate. Some studies suggest that amnesic patients with selective lesion to the hippocampal circuit show a relatively normal recognition memory in the presence of impaired recall. However, other findings did not support this assumption. We investigated the recognition memory performance of a patient (ER) who became amnesic following a carbon monoxide poisoning. The MR scan revealed bilateral lesions to the pallidum. Based on the aetiology, a hippocampal lesion is suspected, but needs to be confirmed by a volumetric analysis. The recall and recognition performance of the patient was tested by means of the nonverbal subtests of the Doors and People Test Battery, which were matched on difficulty. On these subtests, ER’s recall performance was much more impaired than his recognition memory. ER’s recognition memory performance was further examined on a yes-no and a forced-choice recognition memory task, using faces as material. On the yes-no task, ER’s hit rate was normal, but he made a lot of false alarms compared to control subjects. By contrast, his forced-choice recognition memory was completely normal. This suggests that ER is able to use the familiarity process to make recognition decisions. Familiarity and recollection were finally investigated with a recognition task using the Process Dissociation Procedure (Jacoby, 1991). On this task, ER’s familiarity score was normal, whereas his recollection score was lower. These results support the assumption that familiarity-based recognition memory can be preserved in amnesia. [less ▲]

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See detailMemory for temporal context: Effects of aging and retrieval strategies
Bastin, Christine ULg; Van der Linden, Martial ULg

in Proceedings of the International Conference Binding in Human Memory: A neurocognitive approach (2002)

The purpose of the present study was to re-explore the effects of age on memory for temporal context, assessed by a list discrimination task. Contrary to previous studies, each list (with faces as stimuli ... [more ▼]

The purpose of the present study was to re-explore the effects of age on memory for temporal context, assessed by a list discrimination task. Contrary to previous studies, each list (with faces as stimuli) was associated with a different type of judgement (honesty versus intelligence rating). The results showed no age differences on this task when no particular retrieval strategy was induced. However, when participants were encouraged to retrieve the list of occurrence of the items by retrieving the type of judgement made at encoding, there was an age effect. Older adults’ performance was at chance, whereas younger adults had a good performance. Moreover, younger adults who reported using the strategy performed as well as younger adults who did not use it. These results will be discussed by reference to the distinction between automatic versus effortful encoding processes. [less ▲]

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See detailProcessus attentionnels et maladie d'Alzheimer
Collette, Fabienne ULg; Van der Linden, Martial ULg

in Couillet, J.; Leclerq, M.; Moroni, C. (Eds.) et al La neuropsychologie de l'attention (2002)

La maladie d'Alzheimer se caractérise par l'accumulation progressive de déficits affectant différents domaines cognitifs.(...)Il est maintenant largement reconnu que la maladie d'Alzheimer n'affecte pas ... [more ▼]

La maladie d'Alzheimer se caractérise par l'accumulation progressive de déficits affectant différents domaines cognitifs.(...)Il est maintenant largement reconnu que la maladie d'Alzheimer n'affecte pas tous les processus cognitifs de façon équivalente.(...)Les modèles cognitifs de l'attention suggèrent que l'attention n'est pas un système homogène et que différents types de processus attentionnels peuvent être distingués.(...)Le but de ce chapitre est de présenter les travaux les plus représentatifs ayant exploré ces différents types de processus dans la maladie d'Alzheimer. [less ▲]

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See detailAttention disorders in neurodegenerative diseases
Collette, Fabienne ULg; Van der Linden, Martial ULg

in Leclerq, M.; Zimmerman, P. (Eds.) Applied neuropsychology of attention : theory, diagnosis and rehabilitation (2002)

A number of neuropsychological studies in recent years have shown that demented patients do not necessarily present a global deterioration and that the disease can impair some cognitive processes or ... [more ▼]

A number of neuropsychological studies in recent years have shown that demented patients do not necessarily present a global deterioration and that the disease can impair some cognitive processes or systems, while sparing others. Moreover, qualitatively different patterns of cognitive impairment have been identified in association with different types of neurodegenerative dementias, such as Alzheimer's disease, Huntington's disease, Parkinson's disease or frontotemporal dementia. [less ▲]

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See detailAttention and normal ageing
Van der Linden, Martial ULg; Collette, Fabienne ULg

in Leclercq, M.; Zimmerman, P. (Eds.) Applied neuropsychology of attention : theory, diagnosis and rehabilitation (2002)

Over the past twenty-five years, a great deal of evidence has been accumulated indicating that advancing age is accompanied by a systematic decline in performance on a wide variety of cognitive tasks ... [more ▼]

Over the past twenty-five years, a great deal of evidence has been accumulated indicating that advancing age is accompanied by a systematic decline in performance on a wide variety of cognitive tasks, both in the laboratory and in everyday life. However, age-related decline is not observed in all situations and older adults may even show a relative advantage in some tasks. [less ▲]

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See detailNeural and cognitive bases of upper limb apraxia in corticobasal degeneration
Peigneux, Philippe ULg; Salmon, Eric ULg; Garraux, Gaëtan ULg et al

in Neurology (2001), 57(7), 1259-1268

OBJECTIVE: To investigate the neural and cognitive bases of upper limb apraxia in corticobasal degeneration (CBD). METHODS: Eighteen patients with CBD underwent a cognitive neuropsychological assessment ... [more ▼]

OBJECTIVE: To investigate the neural and cognitive bases of upper limb apraxia in corticobasal degeneration (CBD). METHODS: Eighteen patients with CBD underwent a cognitive neuropsychological assessment of apraxia and resting [(18)F]-fluorodeoxyglucose PET scanning. Two complementary measures of apraxia were computed for each modality of gesture production. First, a performance score measured error frequency during gesture execution. Second, as a more stringent test of the integrity of the praxis system, the correction score measured the patient's ability to correct his or her errors on a second attempt. For each measure type, a cut-off score for the presence of apraxia was defined with regard to healthy controls. Using each cut-off score, the regional cerebral glucose metabolism of patients with CBD with apraxia (i.e., performing below cut-off score) was compared with that of patients with CBD without apraxia. RESULTS: Mean performance scores were below normal values in all modalities. Anterior cingulate hypometabolism predominated in patients with CBD who performed below the cut-off performance score. At variance, mean correction scores were below normal values for gesture imitation only. Hypometabolism in superior parietal lobule and supplementary motor area characterized patients with CBD who were unable to correct their errors at the same rate as control subjects did. CONCLUSIONS: Distinct neural networks underlie distinct aspects of the upper limb apraxic deficits in CBD. Extending previous findings of gesture production deficits in CBD, the use of complementary measures of apraxic behavior discloses a visuoimitative upper limb apraxia in CBD, underlain by a metabolic decrease in a parietofrontal neural network. [less ▲]

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See detailThe functional anatomy of inhibition processes investigated with the Hayling task
Collette, Fabienne ULg; Van der Linden, Martial ULg; Delfiore, Guy et al

in Neuroimage (2001), 14(2), 258-267

The cortical areas involved in inhibition processes were examined with positron emission tomography (PET). The tasks administered to subjects were an adaptation of the Hayling test. In the first condition ... [more ▼]

The cortical areas involved in inhibition processes were examined with positron emission tomography (PET). The tasks administered to subjects were an adaptation of the Hayling test. In the first condition (response initiation), subjects had to complete sentences with a word clearly suggested by the context, whereas in the second condition (response inhibition), subjects had to produce a word that made no sense in the context of the sentence. Results indicated that the response initiation processes were associated to increases of activity in the left inferior frontal gyrus (BA 45/47), whereas response inhibition processes led to increases in a network of left prefrontal areas, including the middle (BA 9 and BA 10) and inferior (BA 45) frontal areas. [less ▲]

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See detailWord priming in normal aging with a task that circumvent explicit memory contamination
Adam, Stéphane ULg; Gouvars, Sébastien; Van der Linden, Martial ULg

Poster (2001, July 18)

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See detailAge differences, cognitive control, and prefrontal cortex in the process dissociation procedure
Chicherio, Christian; Ludwig, C.; de Ribaupierre, S. et al

Poster (2001, July 18)

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See detailImpaired controlled recollection processes in depression and subjective memory complaints
Jermann, Françoise; Adam, Stéphane ULg; Ceschi, Grazia et al

Poster (2001, July 18)

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See detailContribution of Lexico-Semantic Processes to Verbal Short-Term Memory Tasks: A Pet Activation Study
Collette, Fabienne ULg; Majerus, Steve ULg; Van der Linden, Martial ULg et al

in Memory (2001), 9(4-6), 249-259

Recent studies have demonstrated the intervention of long-term memory processes in verbal STM tasks and several cognitive models have been proposed to explain these effects. A PET study was performed in ... [more ▼]

Recent studies have demonstrated the intervention of long-term memory processes in verbal STM tasks and several cognitive models have been proposed to explain these effects. A PET study was performed in order to determine whether supplementary cerebral areas are involved when subjects have to execute short-term memory tasks for items having representations in long-term memory (in comparison to items without such representations: words vs non-words). Results indicate that verbal STM for words specifically involves the left middle temporal gyrus (BA 21) and temporo-parietal junction (BA 39). These areas can be associated with lexical and semantic processes. These results are in agreement with cognitive models that postulate the simultaneous influence of lexical and semantic long-term representations on verbal STM processes and/or a lexico-semantic buffer. [less ▲]

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