References of "Van der Linden, Martial"
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See detailExploring the unity and diversity of the neural substrates of executive functioning
Collette, Fabienne ULg; Van der Linden, Martial ULg; Laureys, Steven ULg et al

in Human Brain Mapping (2005), 25(4), 409-423

Previous studies exploring the neural substrates of executive functioning used task-specific analyses, which might not be the most appropriate approach due to the difficulty of precisely isolating ... [more ▼]

Previous studies exploring the neural substrates of executive functioning used task-specific analyses, which might not be the most appropriate approach due to the difficulty of precisely isolating executive functions. Consequently, the aim of this study was to use positron emission tomography (PET) to reexamine by conjunction and interaction paradigms the cerebral areas associated with three executive processes (updating, shifting, and inhibition). Three conjunction analyses allowed us to isolate the cerebral areas common to tasks selected to tap into the same executive process. A global conjunction analysis demonstrated that foci of activation common to all tasks were observed in the right intraparietal sulcus, the left superior parietal gyrus, and at a lower statistical threshold, the left lateral prefrontal cortex. These regions thus seem to play a general role in executive functioning. The right intraparietal sulcus seems to play a role in selective attention to relevant stimuli and in suppression of irrelevant information. The left superior parietal region is involved in amodal switching/integration processes. One hypothesis regarding the functional role of the lateral prefrontal cortex is that monitoring and temporal organization of cognitive processes are necessary to carry out ongoing tasks. Finally, interaction analyses showed that specific prefrontal cerebral areas were associated with each executive process. The results of this neuro-imaging study are in agreement with cognitive studies demonstrating that executive functioning is characterized by both unity and diversity of processes. [less ▲]

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See detailInvolvement of both prefrontal and inferior parietal cortex in dual-task performance
Collette, Fabienne ULg; Olivier, L.; Van der Linden, Martial ULg et al

in Cognitive Brain Research (2005), 24(2), 237-251

This PET study explored the neural substrate of both dual-task management and integration task using single tasks that are known not to evoke any prefrontal activation. The paradigm included two simple ... [more ▼]

This PET study explored the neural substrate of both dual-task management and integration task using single tasks that are known not to evoke any prefrontal activation. The paradigm included two simple (visual and auditory) discrimination tasks, a dual task and an integration task (requiring simultaneous visual and auditory discrimination), and baseline tasks (passive viewing and hearing). Data were analyzed using SPM99. As predicted, the comparison of each single task to the baseline task showed no activity in prefrontal areas. The comparison of the dual task to the single tasks demonstrated left-sided foci of activity in the frontal gyrus (BA 9/46, BA 10/47 and BA 6), inferior parietal gyrus (BA 40), and cerebellum. By reference to previous neuroimaging studies, BA 9/46 was associated with the coordinated manipulation of simultaneously presented information, BA 10/47 with selection processes, BA 6 with articulatory rehearsal, and BA 40 with attentional shifting. Globally similar regions were found for the integration task, except that the inferior parietal gyrus was not recruited. These results confirm the hypothesis that the left prefrontal cortex is implicated in dual-task performance. Moreover, the involvement of a parietal area in the dual task is in keeping with the hypothesis that a parieto-frontal network sustains executive functioning. [less ▲]

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See detailFurther exploration of controlled and automatic memory processes in early Alzheimer's disease
Adam, Stéphane ULg; Van der Linden, Martial ULg; Collette, Fabienne ULg et al

in Neuropsychology (2005), 19(4), 420-427

The authors' aim in this study was to explore automatic and controlled processes in Alzheimer's disease (AD) by using a variant of the word-stem completion task that applies the process-dissociation ... [more ▼]

The authors' aim in this study was to explore automatic and controlled processes in Alzheimer's disease (AD) by using a variant of the word-stem completion task that applies the process-dissociation procedure. Several methodological precautions were taken in order to limit problems observed in previous studies (e.g., poor task sensitivity, ceiling and/or floor effects, no control over comprehension of instructions). Our results (a) confirmed the marked deterioration in controlled processes and (b) showed that when psychometric constraints were limited, automatic memory processes were preserved in AD. These data are in line with those from more global studies in suggesting that AD is characterized by an early deterioration in controlled processes and an initial preservation of automatic processes. [less ▲]

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See detailControlled and automatic uses of memory in depressed patients: effect of retention interval lengths
Jermann, Françoise; Van der Linden, Martial ULg; Adam, Stéphane ULg et al

in Behaviour Research and Therapy (2005), 43(5), 681-690

The present study examines controlled and automatic uses of memory in clinically depressed patients by applying the Process Dissociation Procedure developed by Jacoby (1991) to a stem completion memory ... [more ▼]

The present study examines controlled and automatic uses of memory in clinically depressed patients by applying the Process Dissociation Procedure developed by Jacoby (1991) to a stem completion memory task with short and long retention intervals. The results show that the contribution of controlled processes is lower in depressed patients than in controls, especially for the longest retention interval, whereas the contribution of automatic processes is equivalent in both groups and unaffected by the length of the retention interval. These findings are discussed in a cognitive control framework. (c) 2004 Elsevier Ltd. All rights reserved. [less ▲]

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See detailSelf-referential reflective activity and its relationship with rest : a PET study
D'Argembeau, Arnaud ULg; Collette, Fabienne ULg; Van der Linden, Martial ULg et al

in NeuroImage (2005), 25(2), 616-624

This study used positron emission tomography (PET) to identify the brain substrate of self-referential reflective activity and to investigate its relationship with brain areas that are active during the ... [more ▼]

This study used positron emission tomography (PET) to identify the brain substrate of self-referential reflective activity and to investigate its relationship with brain areas that are active during the resting state. Thirteen healthy volunteers performed reflective tasks pertaining to three different matters (the self, another person, and social issues) while they were scanned. Rest scans were also acquired, in which subjects were asked to simply relax and not think in a systematic way. The mental activity experienced during each scan was assessed with rating scales. The results showed that, although self-referential thoughts were most frequent during the self-referential task, some self-referential reflective activity also occurred during rest. Compared to rest, performing the reflective tasks was associated with increased blood flow in the dorsomedial prefrontal cortex, the left anterior middle temporal gyros, the temporal pole bilaterally, and the right cerebellum; there was a decrease of blood flow in right prefrontal regions,and in medial and right lateral parietal regions. In addition, the ventromedial prefrontal cortex (VMPFC) (1) was more active during the self-referential reflective task than during the other two reflective tasks, (2) showed common activation during rest and the self-referential task, and (3) showed a correlation between cerebral metabolism and the amount of self-referential processing. It is suggested that the VMPFC is crucial for representing knowledge pertaining to the self and that this is an important function of the resting state. [less ▲]

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See detailModulation of brain activity during phonological familiarization
Majerus, Steve ULg; Van der Linden, Martial ULg; Collette, Fabienne ULg et al

in Brain & Language (2005), 92(3), 320-331

We measured brain activity in 12 adults for the repetition of auditorily presented words and nonwords, before and after repeated exposure to their phonological form. The nonword phoneme combinations were ... [more ▼]

We measured brain activity in 12 adults for the repetition of auditorily presented words and nonwords, before and after repeated exposure to their phonological form. The nonword phoneme combinations were either of high (HF) or low (LF) phonotactic frequency. After familiarization, we observed, for both word and nonword conditions, decreased activation in the left posterior superior temporal gyrus, in the bilateral temporal pole and middle temporal gyri. At the same time, interaction analysis showed that the magnitude of decrease of activity in bilateral posterior temporal lobe was significantly smaller for LF nonwords, relative to words and HF nonwords. Decrease of activity in this area also correlated with the size of behavioral familiarization effects for LF nonwords. The results show that the posterior superior temporal gyrus plays a fundamental role during phonological learning. Its relationship to sublexical and lexical phonological processing as well as to phonological short-term memory is discussed. (c) 2004 Elsevier Inc. All rights reserved. [less ▲]

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See detailMemory evaluation with a new cued recall test in patients with mild cognitive impairment and Alzheimer's disease
Ivanoiu, Adrian; Adam, Stéphane ULg; Van der Linden, Martial ULg et al

in Journal of Neurology (2005), 252(1), 47-55

Free delayed recall is considered the memory measure with the greatest sensitivity for the early diagnosis of dementia. However, its specificity for dementia could be lower, as deficits other than those ... [more ▼]

Free delayed recall is considered the memory measure with the greatest sensitivity for the early diagnosis of dementia. However, its specificity for dementia could be lower, as deficits other than those of pure memory might account for poor performance in this difficult and effortful task. Cued recall is supposed to allow a better distinction between poor memory due to concurrent factors and impairments related to the neurodegenerative process. The available cued recall tests suffer from a ceiling effect. This is a prospective, longitudinal study aiming to assess the utility of a new memory test based on cued recall that avoids the ceiling effect in the early diagnosis of Alzheimer's disease (AD). Twenty-five patients with mild cognitive impairment (MCI), 22 probable AD patients ( NINCDS-ADRDA) at a mild stage, 22 elderly patients with subjective memory complaints (SMC) and 38 normal age-matched controls took part in the study. The patients underwent a thorough cognitive evaluation and the recommended screening procedure for the diagnosis of dementia. All patients were re-examined 12 - 18 months later. A newly devised delayed cued recall test using semantic cues ( The RI48 Test) was compared with three established memory tests: the Ten Word-List Recall from CERAD, the "Doors" and the "Shapes" Tests from "The Doors and People Test Battery". Forty-four % of the MCI patients fulfilled criteria for probable AD at follow-up. The RI48 Test classified correctly 88% of the MCI and SMC participants and was the best predictor of the status of MCI and mild AD as well as the outcome of the MCI patients. Poor visual memory was the second best predictor of those MCI patients who evolved to AD. A cued recall test which avoids the ceiling effect is at least as good as the delayed free recall tests in the early detection of AD. [less ▲]

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See detailA quantitative and qualitative assessment of verbal short-term memory and phonological processing in 8-year-olds with a history of repetitive otitis media
Majerus, Steve ULg; Amand, Pierre; Boniver, Vincent et al

in Journal of Communication Disorders (2005), 38(6), 473-498

Language outcome in children experiencing fluctuant hearing loss due to otitis media (OME) remains highly equivocal. In the current study, we assessed performance on highly sensitive verbal short-term ... [more ▼]

Language outcome in children experiencing fluctuant hearing loss due to otitis media (OME) remains highly equivocal. In the current study, we assessed performance on highly sensitive verbal short-term memory (STM), new word learning and phonological processing tasks in 8-year-old children who had suffered from recurrent OME before the age of 3. Relative to a control group with no history of OME, we observed strictly normal performance for different STM and new word learning tasks. Performance on these tasks was also normally influenced by phonotactic, lexical and semantic variables. However, at the level of phonological processing, a small but significant decrease of performance was found in a speeded nonword identification task and a rhyme judgment task. The results of this study suggest that outcome of OME is characterized by subtle impairments at the level of perceptual-phonological analysis, but there is no significant impact on verbal STM and new word learning abilities. Learning outcomes: As a result of this activity, the participant will be able to (1) explain the outcome of recurrent OME before age 3 on later language and verbal STM development, (2) be aware of the complex relationships that link language development and verbal STM, (3) explain how fluctuant hearing loss during infancy and early childhood could affect verbal STM development and learning capacity for new phonological information, (4) describe different verbal STM measures that distinguish retention capacities for phonological and lexico-semantic information, and (5) explain the influence of phonotactic frequency on nonword processing in language and verbal STM tasks. (c) 2005 Elsevier Inc. All rights reserved. [less ▲]

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See detailNonclinical Participants' Reports of Hallucinatory Experiences
Laroi, Frank ULg; Van der Linden, Martial ULg

in Canadian Journal of Behavioural Science = Revue Canadienne des Sciences du Comportement (2005), 37

Hallucinatory experiences in nonclinical subjects were examined using a French adaptation of a self-report questionnaire (Launay-Slade Hallucinations Scale; LSHS). The factor structure of this ... [more ▼]

Hallucinatory experiences in nonclinical subjects were examined using a French adaptation of a self-report questionnaire (Launay-Slade Hallucinations Scale; LSHS). The factor structure of this questionnaire was examined. In addition to prevalence, we explored various characteristics of the reported hallucinatory experiences, including frequency, degree of control, emotional reaction, relationship to stressful events, and personal saliency. We also examined the relationship between the presence of hallucinatory experiences and other factors, such as substance use and social desirability. Two hundred and thirty-six nonclinical participants completed a modified version of the LSHS, a social desirability scale, and answered follow up questions. Factor analysis of the present version of the LSHS revealed a five-factor structure. Results regarding participants' hallucination frequency, perceived levels of control, and affective responses are reported. Additional results and implications are discussed. [less ▲]

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See detailMemory for temporal context : Effects of aging, encoding instructions and retrieval strategies
Bastin, Christine ULg; Van der Linden, Martial ULg

in Memory (2005), 13(1), 95-109

Young and older adults were compared on a list discrimination task. In Experiment 1, performance declined with aging after incidental and intentional encoding of the temporal context. Moreover, there was ... [more ▼]

Young and older adults were compared on a list discrimination task. In Experiment 1, performance declined with aging after incidental and intentional encoding of the temporal context. Moreover, there was no benefit for intentional encoding in either group. In Experiment 2, each list was associated with a different encoding context. There were age differences in performance when participants tried to retrieve the encoding context of the items as a cue for their list of occurrence, but not when participants evaluated temporal distance from the strength of the memory trace. This suggests that the age-related decrease in list discrimination could be at least partly due to a difficulty to infer strategically the temporal context of the items from information encoded in the same time. [less ▲]

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See detailLa mémoire de travail
Collette, Fabienne ULg; Van der Linden, Martial ULg

in Gély-Nargeot, Marie-Christine; Ergis, Anne-Marie; Van der Linden, Martial (Eds.) Les troubles de la mémoire dans la maladie d'Alzheimer (2005)

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See detailPhenomenal characteristics of autobiographical memories for emotional and neutral events in older and younger adults
Comblain, Christine; D'Argembeau, Arnaud ULg; Van der Linden, Martial ULg

in Experimental Aging Research (2005), 31(2), 173-189

The authors investigated age-related differences in phenomenal characteristics of autobiographical memories for positive, negative, and neutral events. Younger and older participants were asked to recall ... [more ▼]

The authors investigated age-related differences in phenomenal characteristics of autobiographical memories for positive, negative, and neutral events. Younger and older participants were asked to recall two specific memories of each type and then to rate their memories on several sensorial ( e. g., visual, taste) and contextual ( e. g., location, time) characteristics. The authors found that emotional ( both positive and negative) memories contained more sensorial and contextual details than neutral memories in both age groups, whereas positive and negative memories did not differ on most dimensions. In addition, negative memories were associated with a higher intensity of positive feelings and a reduced complexity of storyline in older as compared to younger adults. These results suggest that the effect of emotion on phenomenal characteristics of autobiographical memories is similar in younger and older adults, but that older adults tend to reappraise negative events in a more positive light than younger adults. [less ▲]

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See detailInvestigation of automatic memory during general anesthesia for elective surgery using the process dissociation procedure
Willems, Sylvie ULg; Iselin-Chaves, Irène A.; Jermann, Françoise J. et al

in Anesthesiology (2005), 103

Background: This prospective study evaluated memory function during general anesthesia for elective surgery and its relation to depth of hypnotic state. The authors also compared memory function in ... [more ▼]

Background: This prospective study evaluated memory function during general anesthesia for elective surgery and its relation to depth of hypnotic state. The authors also compared memory function in anesthetized and nonanesthetized subjects. Methods: Words were played for 70 min via headphones to 48 patients (aged 18–70 yr) after induction of general anesthesia for elective surgery. Patients were unpremedicated, and the anesthetic regimen was free. The Bispectral Index (BIS) was recorded throughout the study. Within 36 h after the word presentation, memory was assessed using an auditory word stem completion test with inclusion and exclusion instructions. Memory performance and the contribution of explicit and implicit memory were calculated using the process dissociation procedure. The authors applied the same memory task to a control group of nonanesthetized subjects. Results: Forty-seven patients received isoflurane, and one patient received propofol for anesthesia. The mean ( SD) BIS was 49 9. There was evidence of memory for words presented during light (BIS 61–80) and adequate anesthesia (BIS 41–60) but not during deep anesthesia (BIS 21–40). The process dissociation procedure showed a significant implicit memory contribution but not reliable explicit memory contribution (mean explicit memory scores 0.05 0.14, 0.04 0.09, and 0.05 0.14; mean automatic influence scores 0.14 0.12, 0.17 0.17, and 0.18 0.21 at BIS 21–40, 41–60, and 61–80, respectively). Compared with anesthetized patients, the memory performance of nonanesthetized subjects was better, with a higher contribution by explicit memory and a comparable contribution by implicit memory. Conclusion: During general anesthesia for elective surgery, implicit memory persists even in adequate hypnotic states, to a comparable degree as in nonanesthetized subjects. [less ▲]

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See detailMetacognitions in proneness towards hallucinations and delusions
Laroi, Frank ULg; Van der Linden, Martial ULg

in Behaviour research and therapy (2005), 43(11), 1425-1441

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See detailSource monitoring for actions in hallucination proneness
Laroi, Frank ULg; Collignon, O.; Van der Linden, Martial ULg

in Cognitive Neuropsychiatry (2005), 10

INTRODUCTION: In the present study we explored the role of cognitive factors in hallucinatory proneness by utilising an incidental source monitoring task consisting of actions. METHOD: A total of 65 ... [more ▼]

INTRODUCTION: In the present study we explored the role of cognitive factors in hallucinatory proneness by utilising an incidental source monitoring task consisting of actions. METHOD: A total of 65 normal subjects were administered a source monitoring task and were asked either to: (1) perform the action; (2) watch the experimenter perform the action; (3) imagine him/herself performing the action; (4) imagine the experimenter performing the action; (5) or listen to the experimenter say the action verbally. Following a delay, actions were presented consisting of those already presented in one of the 5 conditions (old), and those never before presented (new). For each action, subjects were required to identify if the action was old or new. If the action was identified as old, subjects were required to identify the source of the word (i.e., one of the 5 conditions). Subjects also completed a questionnaire assessing metacognitive beliefs. Subjects were grouped according to their scores on a revised and elaborated version of the Launay-Slade Hallucinations Scale (LSHS). Those with scores within the top 25% were included in the hallucination-prone group (HP) (n = 16), whereas scores within the lower 25% were included in the nonhallucination-prone group (NHP) (n = 16). RESULTS: Within the internal conditions, hallucination-prone subjects confused two internal sources (a specific internal-internal source discrimination error). That is, for imagined actions where the subjects performed the action, HP subjects erroneously attributed these towards an imagined action performed by the experimenter. Results also revealed that hallucination-proneness was associated with metacognitive beliefs. Finally, there was a significant relation between certain metacognitive beliefs and the internal-internal source discrimination error on the source monitoring task. CONCLUSIONS: Findings from the present study suggest that an important cognitive deficit in the genesis of hallucinations may be a perturbation in the control of interna [less ▲]

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See detailAssociations between hallucinations and personality structure in a non-clinical sample : comparison between young and elderly samples
Laroi, Frank ULg; DeFruyt, F.; van Os, J. et al

in Personality and Individual Differences (2005), 39(1), 189-200

Few studies have explored the prevalence of hallucinations in the non-clinical, elderly population. Also, the association between personality structure and hallucinations remains poorly investigated. The ... [more ▼]

Few studies have explored the prevalence of hallucinations in the non-clinical, elderly population. Also, the association between personality structure and hallucinations remains poorly investigated. The aims of the present study were twofold. First, to explore the influence of age on the prevalence of hallucination-proneness, and second, to examine the association between personality and hallucination-proneness in young and elderly subjects. A sample of young (n = 230) and elderly adults (n = 183) completed an elaborated and validated version of the Launay-Slade Hallucinations Scale (LSHS; Laroi, Marczewski, & Van der Linden, 2004) and the Five Factor Inventory version of the NEO Personality Inventory (NEO-FFI; Costa, [less ▲]

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See detailDissociation between recall and recognition memory in amnesia: The case of a patient with hippocampal damage following carbon monoxide poisoning
Bastin, Christine ULg; Van der Linden, Martial ULg; Charnallet, Annik et al

in Proceedings of the Joint Mid-year meeting of the International Neuropsychological Society, the Division of Neuropsychology of the British Psychological Society and the British Neuropsychological Society (2005)

There is currently a debate regarding the status of recall and recognition memory in amnesic patients with focal hippocampal damage. Proportionate deficits of recall and recognition memory have been ... [more ▼]

There is currently a debate regarding the status of recall and recognition memory in amnesic patients with focal hippocampal damage. Proportionate deficits of recall and recognition memory have been observed in some patients with selective hippocampal damage. In addition, these patients showed an impairment of both the recollection and familiarity aspects of recognition memory. In contrast, other amnesic patients with selective hippocampal lesions demonstrated relatively preserved recognition memory, despite severely impaired recall abilities. In some of them, familiarity processes were found to be intact. The resolution of this controversy has important implications for theories of episodic memory. In the present study, we examined the recall and recognition performance of an amnesic patient, MR, who suffered from bilateral hippocampal damage and temporoparietal cortical atrophy following carbon monoxide poisoning. Verbal and nonverbal recall and recognition memory were measured by tasks matched for difficulty. On these tasks, MR’s recall performance was more severely impaired than his recognition memory. In addition, MR’s recognition performance was normal on most of the tasks. In order to determine on which processes MR based his recognition decisions, we administered to the patient and to matched controls the process dissociation procedure. This evaluates the contribution of recollection and familiarity within a recognition task. The results indicated that, in this patient, familiarity was preserved, but recollection was impaired. This study thus supports the idea that amnesic patients with hippocampal damage can show preserved familiarity-based recognition memory, despite poor recall and recollection. [less ▲]

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See detailMémoire du contexte temporel: Effets du vieillissement, des instructions d'encodage et des stratégies de récupération
Bastin, Christine ULg; Van der Linden, Martial ULg

in Taconnat, Laurence; Vanneste, Sandrine; Isingrini, Michel (Eds.) Manifestations cognition du vieillissement psychologique (2005)

We explored the effects of aging on memory for the temporal context, assessed by a list discrimination task with unfamiliar faces. In a first experiment, we compared incidental and intentional encoding of ... [more ▼]

We explored the effects of aging on memory for the temporal context, assessed by a list discrimination task with unfamiliar faces. In a first experiment, we compared incidental and intentional encoding of the temporal context in young and older adults. The results indicated that list discrimination performance declines with aging. Moreover, intentional encoding of the temporal context does not improve performance of neither group, compared to incidental encoding. In a second experiment, each list was associated with a different encoding context. The results showed age differences on list discrimination performance when participants tried to remember the encoding context of the items as a cue to retrieve their list of occurrence. However, there is no age difference when participants relied on some other processes, mainly involving the assessment of the strength of the memory for the item. The difficulty of older adults to use a reconstruction process may be partly due to a less efficient encoding of the contextual information necessary to reconstruct the temporal context of the event. [less ▲]

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See detailPhenomenal characteristics associated with projecting oneself back into the past and forward into the future: Influence of valence and temporal distance
D'Argembeau, Arnaud ULg; Van der Linden, Martial ULg

in Consciousness & Cognition (2004), 13(4), 844-858

As humans, we frequently engage in mental time travel, reliving past experiences and imagining possible future events. This study examined whether similar factors affect the subjective experience ... [more ▼]

As humans, we frequently engage in mental time travel, reliving past experiences and imagining possible future events. This study examined whether similar factors affect the subjective experience associated with remembering the past and imagining the future. Participants mentally "re-experienced" or "pre-experienced" positive and negative events that differed in their temporal distance from the present (close versus distant), and then rated the phenomenal characteristics (i.e., sensorial, contextual, and emotional details) associated with their representations. For both past and future, representations of positive events were associated with a greater feeling of re-experiencing (or pre-experiencing) than representations of negative events. In addition, representations of temporally close events (both past and future) contained more sensorial and contextual details, and generated a stronger feeling of re-experiencing (or pre-experiencing) than representations of temporally distant events. It is suggested that the way we both remember our past and imagine our future is constrained by our current goals. (C) 2004 Elsevier Inc. All rights reserved. [less ▲]

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