References of "Van Galen, Gaby"
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See detailEffect of breed on Doppler echocardiographic measurements in equids
Al Haidar, A; Sandersen, Charlotte ULg; Van Erck, Emmanuelle et al

in Proceedings of the 3rd Annual Congress of the European College of Equine Internal Medicine (ECEIM) (2009)

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See detailGestion médicale des myopathies: les premiers gestes
Votion, Dominique ULg; Van Galen, Gaby ULg; Caudron, Isabelle et al

in Pratique Vétérinaire Equine (2009), 41(numero special), 119-126

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See detailVariations of plasmatic concentrations of Insulin-like Growth Factor-I in post-pubescent horses affected with developmental osteochondral lesions.
Verwilghen, Denis ULg; Vander Heyden, Laurent ULg; Franck, Thierry ULg et al

in Veterinary Research Communications (2009)

Developmental osteochondral lesions are often encountered in the equine population and are a major cause of lameness. Different growth factors that act systemically as well as locally regulate the growth ... [more ▼]

Developmental osteochondral lesions are often encountered in the equine population and are a major cause of lameness. Different growth factors that act systemically as well as locally regulate the growth of cartilage. Among them is Insulin-like Growth Factor I that has been demonstrated to promote chondrocyte growth and differentiation and that has been shown to influence cartilage repair. The aims of this study were to investigate differences in circulating plasma levels of Insulin-like Growth Factor-I in post-pubescent horses affected with developmental osteochondral lesions compared to unaffected ones. Significantly higher values of circulating Insulin-like Growth Factor-I levels were found in the affected group (n = 82) compared to controls (n = 86). This result may still reflect an earlier imbalance in IGF-I levels from horses with developmental osteochondral lesions considering the aetiopathological link which has been made between IGF-I and the occurrence of osteochondrosis. However, other studies have shown increased expression of IGF-I after cartilage damage. The higher levels found in this study could be due to a healing response of the cartilage to the damage caused by the osteochondral lesions. [less ▲]

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See detailAtypical Myopathy In Grazing Horses: A First Exploratory Data Analysis
Votion, Dominique ULg; Linden, Annick ULg; Delguste, Catherine ULg et al

in Veterinary Journal (2009), 180(1),

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See detailLe diagnostic différentiel des troubles musculaires
Van Galen, Gaby ULg; Votion, Dominique ULg

Conference (2008, October 10)

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See detailRésultats préliminaires d’une étude sur les biopsies rectales prélevées avec une pince à biopsie utérine
Leroux, Aurélia ULg; Amory, Hélène ULg; Van Galen, Gaby ULg

Poster (2008, October 09)

Introduction : La description pratique de la technique de biopsie rectale dans l’espèce équine diffère d’un auteur à l’autre. Pour obtenir des échantillons représentatifs, il est souvent suggéré effectuer ... [more ▼]

Introduction : La description pratique de la technique de biopsie rectale dans l’espèce équine diffère d’un auteur à l’autre. Pour obtenir des échantillons représentatifs, il est souvent suggéré effectuer les biopsies à l’aveugle au moyen d’une pince à biopsie utérine plutôt que par endoscopie rectale. Les sites de prélèvement préconisés sont variables. Même si tous les auteurs s’accordent à dire qu’il faut réaliser la biopsie en arrière du cul-de-sac rétropéritonéal [1] [2], la distance de prélèvement en avant de l’anus varie de 15 cm [2] [5] à 30 cm [1] [3]. De plus, le prélèvement est réalisé tantôt au plafond [1] [5], tantôt au plancher [3] du rectum. De nombreux auteurs évoquent le très faible risque de complication suite à la biopsie rectale [1] [4], mais la perforation, l’abcès périrectal et la péritonite septique ont été décrits [2]. Objectifs : Le but de cette étude est d’évaluer les risques associés à la technique de biopsie rectale réalisée au moyen d’une pince à biopsie utérine. Méthodes : Cette étude a été effectuée sur 11 chevaux destinés à l’euthanasie : les 7 premiers ont été biopsiés sous anesthésie générale, et les 4 autres ont été biopsiés debout sous tranquillisation (0,01mg/kg détomidine IV ou 0,6mg/kg xylazine IV). Résultats : Aucun des 4 chevaux biopsiés debout n’a montré de signes de douleur au cours de la procédure. Pour un droitier, il s’est avéré plus facile d’effectuer la biopsie rectale avec la pince dans la main droite et la muqueuse rectale dans la main gauche et de prélever à 2H. Discussion et conclusions : La biopsie rectale est facile à faire et bien supportée sur le cheval tranquillisé, bien qu’elle soit fréquemment associée à des hémorragies locales. Le prélèvement devrait être fait à moins de 15 cm de profondeur pour réduire les risques de péritonite. Il est en outre conseillé d’effectuer les biopsies à 10H (gaucher) ou 2H (droitier) pour faciliter techniquement l’acte et réduire les risques d’hématomes. Attendu que l’euthanasie a été effectuée juste après les biopsies, le développement éventuel d’autres complications n’a pas été évalué dans cette étude. Dans une étude suivante, l’aspect histologique des prélèvements obtenus par biopsie sera évalué et comparé à celui obtenu post-mortem. References 1. BRAZIL T. (2007) How to: duodenal and rectal biopsy, BEVA Congress 2007 Proceedings, 66-67. 2. DEBOWES R.M. (1991) Standing rectal and tail surgery, Vet. Clin. North Am. Equine Pract., 7 : 3, 649-667. 3. LINDBERG R., NYGREN A., PERSSON S.G.B. (1996) Rectal biopsy diagnosis in horses with clinical signs of intestinal disorders: a retrospective study of 116 cases. Equine Vet. J., 28 : 4, 275-284. 4. PLUMMER P.J. (2006) Malabsorptive maldigestive disorder with concurrent Salmonella in a 3-year-old quarter horse. Vet. Clin. North Am. Equine Pract., 22 : 1, 85-94. 5. TAMZALI Y. (2006) Chronic weight loss syndrome in the horse: a 60 case retrospective study. Equine Vet. Educ., 18 : 6, 289-296. [less ▲]

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See detailConduite à tenir face a un cas de myopathie atypique du cheval au pré
Van Galen, Gaby ULg; Serteyn, Didier ULg; Marcillaud Pitel, Chistel et al

(2008, October)

Owing to the systematic recording of epidemiological and clinical data of European cases of atypical myopathy via the « Atypical Myopathy Alert Group » (AMAG) risk factors for AM have been recognized ... [more ▼]

Owing to the systematic recording of epidemiological and clinical data of European cases of atypical myopathy via the « Atypical Myopathy Alert Group » (AMAG) risk factors for AM have been recognized. Preventive measures may be advised from the identified demographic, managemental and environmental risk factors for atypical myopathy. From the clinical course of affected horses and the review of the lately published scientific papers, a symptomatic treatment is proposed as well as a supportive therapy based on the recently identified pathological process involved in atypical myopathy. [less ▲]

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See detailEvaluation of sedation depth and quality of performed procedures following administration of α2-agonists combined or not with butorphanol in horses.
Barbry, Stephanie; Verwilghen, Denis ULg; Van Galen, Gaby ULg et al

Poster (2008, October)

Several molecules available in equine medicine provide profound sedation and good analgesia when performing diagnostic or surgical procedures. They differ slightly in degree of action, as well in time as ... [more ▼]

Several molecules available in equine medicine provide profound sedation and good analgesia when performing diagnostic or surgical procedures. They differ slightly in degree of action, as well in time as in depth. The aim of this study was to evaluate the depth of sedation and quality of performing a standardized procedure after injection of an 2-agonist alone or associated with butorphanol. Horses presented to the Equine Clinic of Liege University from December 2007 to June 2008 for an endoscopic, dental, radiological or ophthalmological examination of which owner and clinician agreed to include the horse in the study were retained. All horses (n=133) were sedated in a randomized double blind fashion using one of the six following protocols: detomidine (D) (0.01mg/kg IV), romifidine (R) (0.04mg/kg IV), or xylazine (X) (0.5mg/kg IV) alone or associated with butorphanol (B) (0.02mg/kg IV). Stability, head position and the reaction to a stimulus (auditive and visual) were evaluated before the start of the procedure. An overall subjective grade using a 10 cm line scale was given to evaluate sedation depth (ranging from no effect to maximal depth on line) and the quality of the performed procedure (ranging from not realised to ideal examination). For each specific procedure, the same clinician experienced in his particular field evaluated the parameters. Data were related by a variance analysis using SAS system and considered significant if P<0.01. The used protocols significantly influenced both sedation depth and examination quality. Sedation depth increased significantly when B was added in all the three 2-agonists used (mean ± SD): D: 6.46±0.33; D+B: 7.06±0.37; R: 4.93±0.46; R+B: 7.04±0.45; X: 4.94±0.43; X+B: 7.75±0.40. Detomidine provided a significantly better quality of the examination compared to romifidine and xylazine. The addiction of butorphanol significantly decreased the examination quality when added to detomidine and increased the quality when combined with romifidine and xylazine. Mean (± SD) of the quality of performed procedures: D: 8.41±0.54; D+B: 6.06±0.64; R: 6.68±0.71; R+B: 7.16±0.67; X: 4.47±0.67; X+B: 4.52±0.64. Comparison of sedation depth and quality of performed examination revealed an increase in quality of examination scores with increasing depth of sedation until a certain level. As from sedation depths with scores of 8 or more, a decrease in quality of examination was encountered. This report shows the important effect of butorphanol addition on sedation. However, increasing sedation depth was not necessarily linked to a better quality of procedure, notably due to difficulties in handling strongly sedated horses for the procedures performed in this study. [less ▲]

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See detailThe T-cell population in lesions of polyneuritis equi
Van Galen, Gaby ULg; Amory, Hélène ULg; Cehak, Anja et al

in In Proceedings of the 45th Annual Congress of the British Equine Veterinary Association (2008, September 11)

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See detailMandibular osteodistraction for correction of deep bite class II malocclusion in a horse
Verwilghen, Denis ULg; Van Galen, Gaby ULg; Vander Heyden, Laurent ULg et al

in Veterinary Surgery : The Official Journal of the American College of Veterinary Surgeons (2008), 37(6), 571-579

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See detailEpidemiological and pathophysiological study of atypical myopathy in grazing horses
Van Galen, Gaby ULg

Master of advanced studies dissertation (2008)

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See detailThe Composition of the Inflammatory Infiltrate in Three Cases of Polyneuritis Equi
Van Galen, Gaby ULg; Cassart, Dominique ULg; Sandersen, Charlotte ULg et al

in Equine Veterinary Journal (2008), 40(2), 185-8

Polyneuritis equi (PNE) is a rare neurological disease in the horse. Because of the suspicion in PNE of a T-lymphocyte mediated immune response against the myelin, the objective of this study was to ... [more ▼]

Polyneuritis equi (PNE) is a rare neurological disease in the horse. Because of the suspicion in PNE of a T-lymphocyte mediated immune response against the myelin, the objective of this study was to determine the composition of the inflammatory infiltrate in the involved nerves of 3 horses with PNE, studied retrospectively. T-lymphocytes were demonstrated in the lesions, which suggests a T-lymphocyte mediated immune response against myelin. In addition, the presence of B-lymphocytes indicated a local production of antibodies. More research, involving a prospective study, is needed to determine whether the T-lymphocytes are cytotoxic or T-helper lymphocytes. [less ▲]

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See detailApproche diagnostique des myopathies chez le cheval
Van Galen, Gaby ULg; Serteyn, Didier ULg; Amory, Hélène ULg et al

in Le nouveau Praticien vétérinaire équine (2008), 15

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See detailVegetative endocarditis in the horse: retrospective study
Porter, Sarah ULg; Saegerman, Claude ULg; Van Galen, Gaby ULg et al

in Journal of Veterinary Internal Medicine (2008), 22(6), 1411-1416

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See detailAtypical myopathy: new insights into the pathophysiology, prevention and management of the condition
Van Galen, Gaby ULg; Serteyn, Didier ULg; Amory, Hélène ULg et al

in Equine Veterinary Education (2008), 20(5), 234-238

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See detailTetanus in the equine species: a retrospective study of 31 cases.
Van Galen, Gaby ULg; Delguste, Catherine ULg; Sandersen, Charlotte ULg et al

in Tijdschrift voor Diergeneeskunde (2008), 133(12), 512-7

BACKGROUND: Few studies exist about factors affecting the outcome of horses with tetanus. ANIMALS: 31 equids (30 horses and 1 donkey) with a clinical diagnosis of tetanus admitted to the Equine Clinic of ... [more ▼]

BACKGROUND: Few studies exist about factors affecting the outcome of horses with tetanus. ANIMALS: 31 equids (30 horses and 1 donkey) with a clinical diagnosis of tetanus admitted to the Equine Clinic of the University of Liege between 1991 and 2006. The cases were divided into two groups according to the outcome (survivors and non-survivors). METHODS: The clinical data of survivors and non-survivors were compared using an ANOVA (continuous data) or a Fisher's test (discrete data). RESULTS: The survival rate was 32%. Most animals were 5 years or younger, and none had been appropriately vaccinated. The non-survivors were significantly younger than the survivors. The development of dyspnoea, recumbency, and the combination of dysphagia, dyspnoea, and recumbency was observed significantly more in the non-survivors than in the survivors. The timing of tetanus antitoxin administration (either immediately after the onset of suggestive signs or after a delay) was not different between the two groups. The time between the occurrence of a wound and the first signs ranged from 2 days to 2 months and was not significantly different between groups. All non-survivors died within 8 days of the first signs. CONCLUSIONS & CLINICAL IMPORTANCE: This study suggests that young animals are affected more often and more severely by tetanus than older animals. Dyspnoea, recumbency, and the combination of dysphagia, dyspnoea, and recumbency can be considered as indicators of a poor prognosis in equids suffering from tetanus. [less ▲]

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See detailThe use of radial extracorporeal shockwave therapy in the treatment of urethral urolithiasis in the horse: a preliminary study.
Verwilghen, Denis ULg; Ponthier, Jérôme ULg; Van Galen, Gaby ULg et al

in Journal of Veterinary Internal Medicine (2008), 22(6), 1449-51

BACKGROUND: Radial extracorporeal shockwave therapy (ESWT) is widely used in equine practice for the treatment of orthopedic problems. However, its original use as a lithotripsy device in human and canine ... [more ▼]

BACKGROUND: Radial extracorporeal shockwave therapy (ESWT) is widely used in equine practice for the treatment of orthopedic problems. However, its original use as a lithotripsy device in human and canine urology led us to postulate that it could be used as an alternative to the surgical treatment of urethral calculi in horses. HYPOTHESIS: Radial ESWT can easily and safely fragment calculi in the distal urethra of the horse. ANIMALS: Two postmortem cases and 1 live case of obstructive urinary disease admitted at the Veterinary Teaching Hospital of Liege. METHODS: A radial shockwave device was directly applied to the urethra in an attempt to fragment calculi. An ex vivo trial was performed on the same retrieved calculi to investigate pressure settings in order to obtain complete fragmentation of the calculus. RESULTS: In all cases, radial ESWT was able to fragment the calculus partially, enabling retrieval of the remaining fragments via the urethra. Much higher pressure settings than those used for in vivo partial fragmentation were necessary to obtain complete destruction of the calculi ex vivo. CONCLUSIONS AND CLINICAL IMPORTANCE: This brief report suggests the use of radial ESWT as a safe and useful alternative to more invasive surgical management of urethral calculi in horses. [less ▲]

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See detailTetanus in the horse
Van Galen, Gaby ULg; Amory, Hélène ULg

Conference (2007, April 28)

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