References of "VALDES SOCIN, Hernan Gonzalo"
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See detailFamilial secreting-pinealomas : biological and preliminary genetic studies
Allouch, A.; Valdes Socin, Hernan Gonzalo ULg; Hendrick, J. C. et al

in 10th Meeting of the European Neuroendocrine Association - Abstract book (2002)

Introduction: Sporadic pinealomas are intracranial tumors which incidence account for less than 1/107. This is the second report of secretory familial pinealoma in a mother and sister. We report for the ... [more ▼]

Introduction: Sporadic pinealomas are intracranial tumors which incidence account for less than 1/107. This is the second report of secretory familial pinealoma in a mother and sister. We report for the first time neuroendocrine and preliminary genetic studies in these benign tumors. Methods and patients: Radioimmunoassay of urinary 6-sulphatoxymelatonin (a-MT6s) was performed in patients and in 90 control subjects aged 19-67 years. Samples were collected at 19-23 , 23-07 and 07-11 h. Endocrine studies including PRL, TSH, LH, FSH, ACTH, IGF1 and tumoral markers (bHCG, NSE, CEA) levels were measured. Lymphocytes caryotype was determined by CGH. Pituitary and pineal MRI were done in both patients. Results: The daughter was the index case. Diagnosis was done because of headaches. Pineal MRI showed a 17 x 14x 25 mm cystic lesion with gadolinium enhancement and no ventricular dilatation. Circadian rhythm of urinary a-MT6s was present but a-MT6s levels were clearly elevated compared to age-matched controls: 1455 ng/h at 19-23hs (308  261), 6012 ng/h at 23-07hs (1423753) and 3280 ng/h at 07-11hs (579340). The 55 years-old mother reported similar complaints during the daughter's follow-up. A pineal MRI identified a 18 x 20 x 14 mm cystic lesion. There were no signs of intracranial hypertension. None of the women reported sleep disturbances. Circadian rhythm of urinary a-MT6s was lost but a-MT6S levels were clearly elevated : 2380 ng/h at 19-23hs (173  153), 2812 ng/h at 23-07hs (768486) and 1897 ng/h at 07-11hs (480383). Endocrine studies and tumoral markers were in the normal range. No chromosomal abnormalities were found in both women (46,XX). Discussion: Due to the rare occurrence of sporadic pinealomas it is unlikely that such a tumor afflict two members in the same family. Although no histological proof was obtained in our patients, radiological findings and tumoral hypersecretion of melatonin derivated a-MT6s clearly suggest the pineal origin of these tumors. We suggest an autosomal dominant form of transmission with incomplete dominance as the most probable model of inheritance of familial pinealoma. [less ▲]

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See detailHyperthyroïdie sur Amiodarone : études complémentaires, traitement et suivi de 32 cas
Valdes Socin, Hernan Gonzalo ULg; Leisteidt, S.; Betea, Daniela ULg et al

in XXème Congrès de la Société Française d'Endocrinologie - Abstract book (2002)

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See detailAcromégalie : Diabète, intolérance au glucose et sensibilité à l'insuline
Valdes Socin, Hernan Gonzalo ULg; Vroonen, Laurent ULg; Betea, Daniela ULg et al

in XXème Congrès de la Société Française d'Endocrinologie - Abstract book (2002)

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See detailSevere Growth hormone deficiency in non diabetic patients with corticotroph microadenomas : effects of pituitary surgery and implications for GH replacement
Valdes Socin, Hernan Gonzalo ULg; Laret, V.; de Fays, C. et al

in 10th Meeting of the European Neuroendocrine Association - Abstract book (2002)

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See detailPinéalomes familiaux : Etudes biologiques et génétiques préliminaires
Allouch, A.; Valdes Socin, Hernan Gonzalo ULg; Hendrick, J. C. et al

in XXème Congrès de la Société Française d'Endocrinologie - Abstract book (2002)

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See detailDéficience sévère en hormone de croissance chez les patients non diabétiques avec un microadénome corticotrope : Effets de la chirurgie hypophysaire et implications thérapeutiques
Valdes Socin, Hernan Gonzalo ULg; Laret, V.; de Fays, C. et al

in XXème Congrès de la Société Française d'Endocrinologie - Abstract book (2002)

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See detailClinical and genom-wide linkage studies of a multigénérational family with acromegaly and the exclusion of requiem gene
Khoo, S. K.; Chan, S.; Pendek, R. et al

in The Endocrine Society's 84th Annual Meeting - Abstract book (2002)

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See detailFamilial isolated pituitary tumors : clinical and molecular studies in 80 patients
Valdes Socin, Hernan Gonzalo ULg; Jaffrain-Réa, M. L.; Tamburrano, G. et al

in The Endocrine Society's 84th Annual Meeting - Abstract book (2002)

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See detailManagement of hypercalcemia from Parathyroid Carcinoma by immunisation
Betea, Daniela ULg; Bradwell, A. R.; Valdes Socin, Hernan Gonzalo ULg et al

in The Endocrine Society's 84th Annual Meeting - Abstract book (2002)

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See detailFamilial Pituitary tumors
Valdes Socin, Hernan Gonzalo ULg; Poncin, J.; Vanbellinghen, Jean-François ULg et al

in Neuroendocrinologica : Dalla Riserca di base alla Clinica (2002)

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See detailCarcinome parathyroïdien : Contrôle de l'hypercalcémie par immunothérapie
Betea, Daniela ULg; Bradwel, A.; Valdes Socin, Hernan Gonzalo ULg et al

in Annales d'Endocrinologie : XIXe Congrès de la Société Française d'Endocrinologie - Abstract book (2001)

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See detailMétamorphose d'une acromégalie en un adénome hypophysaire non-fonctionnel : Etudes clinique et génétiques
Valdes Socin, Hernan Gonzalo ULg; Stevenaert, Achille ULg; Legros, Jean-Jacques ULg et al

in Annales d'Endocrinologie : XIXe Congrès de la Société Française d'Endocrinologie - Abstract book (2001)

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See detailLes tumeurs à calcitronine extrathyroïdiennes
Valdes Socin, Hernan Gonzalo ULg; Corhay, Jean-Louis ULg; de Leval, Laurence ULg et al

in Annales d'Endocrinologie : XIXe Congrès de la Société Française d'Endocrinologie - Abstract book (2001)

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See detailMetamorphosis of acromegaly to a non-functioning pituitary adenoma
Valdes Socin, Hernan Gonzalo ULg; Stevenaert, Achille ULg; Legros, Jean-Jacques ULg et al

in 5th European Congress of Endocrinology - Abstract book (2001)

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See detailStruma Ovarii toxique : Etudes Génétiques
Valdes Socin, Hernan Gonzalo ULg; Parma, J.; Vassart, G. et al

in Annales d'Endocrinologie : XIXe Congrès de la Société Française d'Endocrinologie - Abstract book (2001)

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See detailLa TSH recombinante (rHTSH) dans le traitement du cancer thyroïdien métastatique
Betea, Daniela ULg; Valdes Socin, Hernan Gonzalo ULg; Beckers, Albert ULg

in Annales d'Endocrinologie : XIXe Congrès de la Société Française d'Endocrinologie - Abstract book (2001)

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See detailSurgical outcome inagromecalics treated with somatostatin analogues before surgery
Stevenaert, Achille ULg; Valdes Socin, Hernan Gonzalo ULg; Flandroy, P. et al

in 5th European Congress of Endocrinology - Abstract book (2001)

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See detailApport du cathétérisme des sinus pétreux inférieux (CSPI) dans la prédiction de la localisation d'un adénome hypophysaire
Valdes Socin, Hernan Gonzalo ULg; Bataille, Yoann ULg; Meurisse, Nicolas ULg et al

in Annales d'Endocrinologie : XIXe Congrès de la Société Française d'Endocrinologie - Abstract book (2001)

Detailed reference viewed: 21 (2 ULg)