Comparison of hydrodynamic parameters obtained by 2D measurements in a flat rectangular column with X-ray radiography and data from literature on 3D columns

Poster (2010)

Hydrodynamic tests are performed in a flat rectangular column packed with two sheets of Mellapak 250 Y (Sulzer structured packing). Measurements are realized with a single phase liquid flow as well as ... [more ▼]

Hydrodynamic tests are performed in a flat rectangular column packed with two sheets of Mellapak 250 Y (Sulzer structured packing). Measurements are realized with a single phase liquid flow as well as with a gas-liquid counter-current flow. Hydrodynamic parameters are compared to experimental results obtained in 3D columns found in the literature, as well as to literature model predictions and to values computed using an in-house Lattice Boltzmann CFD simulation code. [less ▲]

Measurement of liquid hold-up in catalytic structured packings: comparison of different experimental techniques

in de Haan, A. B.; Kooijman, H.; Gorak, A. (Eds.) Proceedings of 9th Distillation and Absorption Conference (DA2010), Eindhoven, Pays-Bas, 12-15 septembre 2010 (2010)

This paper presents the results of an experimental study carried out to examine liquid hold-up in 100 mm diameter catalytic structured packing Katapak-SP. Two versions of the packing have been ... [more ▼]

This paper presents the results of an experimental study carried out to examine liquid hold-up in 100 mm diameter catalytic structured packing Katapak-SP. Two versions of the packing have been investigated. Both global and local measurements were carried out on the very same packings, using water at ambient conditions as working liquid. To this scope, traditional methods like draining techniques were used to obtain global hold-up values. A non-intrusive high energy X-ray tomography was used for gathering information on local scale and study axial distribution of the liquid hold-up over the packed column, inside and outside the catalyst containing baskets. The total liquid hold-up of the catalytic packed bed was evaluated by averaging hold-up values obtained at different cross sections over the corresponding volume. Very good agreement was found between global values estimated with the different techniques. The experimental results are useful for supporting theoretical developments in hydrodynamic and mass transfer modeling. [less ▲]

Lattice Boltzmann 3D flow simulation based on X-ray microtomographic images of activated carbon beds

Poster (2010)

Stochastic modelling of micro-organisms displacements in a stirred-tank bioreactor

Poster (2010)

Dynamic adsorption of methyl iodide on carbon beds obtained from poly(ethylene) terephthalate wastes followed by X-ray microtomography

Poster (2010)

Interfacial area measurement in a catalytic distillation packing using high energy x-ray CT

in Chemical Engineering Science (2010), 65(1), 511-516

In this paper, we report on the use of X-ray tomography to visualize and quantify the gas–liquid interfacial area in modular catalytic distillation packing elements. The calculation method is based on ... [more ▼]

In this paper, we report on the use of X-ray tomography to visualize and quantify the gas–liquid interfacial area in modular catalytic distillation packing elements. The calculation method is based on processing of tomographic images. It is validated by comparing specific surface area determined on dry packings (Mellapak™ 752Y and Katapak™ SP12) tomographic binary images (gas and solid) to values announced by manufacturers, based on geometrical considerations. These data agree fairly well. However, tomographic images show that the specific area is not distributed uniformly over the height of a packing element due to the presence of perforations in corrugated sheets and of wall wipers between the packing and the column wall. X-ray tomography is a unique technique to access to the spatial distribution of these geometrical details in a non-intrusive way. The method used to determine the specific surface area of dry packing is then applied to irrigated packing in order to determine the gas–liquid interfacial area. The axial distribution of the interfacial area is non-uniform and is correlated to the packing specific area. The maxima of the specific surface area correspond to the presence of wall wipers. The gas–liquid interfacial area averaged over the column length is determined. It increases logically with the liquid superficial velocity and slightly with the gas velocity. The effect of the gas velocity is however more pronounced when reaching loading point. [less ▲]

Quality of mixing in a stirred bioreactor used for animal cells culture: heterogeneities in a lab scale bioreactor and evolution of mixing time with scale up

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2010), 14

Animal cells are industrially cultivated inside stirred bioreactors to produce proteinic compounds. Due to the use of mild agitation conditions in order to limit mechanical constraints, the homogeneity of ... [more ▼]

Animal cells are industrially cultivated inside stirred bioreactors to produce proteinic compounds. Due to the use of mild agitation conditions in order to limit mechanical constraints, the homogeneity of the culture medium can be far from perfect. This study has therefore two objectives. 1) the global characterization of the mixing via the mixing time 2) the local description of concentration fields. The mixing time is measured by conductimetry inside 20 L, 80 L, 600L tanks. The Grenville correlation is adjusted on these experimental measurements to improve the prediction of the mixing time during the scale-up of the process. The concentration fields are visualized by the Planar Laser Induced Fluorescence (P.L.I.F) technique in the 20 L tank. This part of the study is focused on the time evolution of the maximum value of the tracer concentration inside measurement planes and of the numerical distribution of theses concentration fields. [less ▲]

Effet de la viscosité sur la structure de l'écoulement et sur le mélange dans un bioréacteur à cuve agitée utilisé en culture de cellules animales

Poster (2009, October 14)

Study of the mixing time evolution during the scale-up of an animal cells culture in a stirred tank bioreactor

Poster (2009, April 01)

Effet de la viscosité sur la structure de l'écoulement et sur le mélange dans un bioréacteur à cuve agitée utilisé en culture de cellules animales

in Récents Progrès en Génie des procédés - A la croisée des sciences et des cultures, pour relever les défis industriels du XXIème siècle (2009)