References of "Thoreau, François"
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See detailPratiques de l'enquête (Ouvrage collectif aux Presses Universitaires de Liège, en cours d'élaboration)
Pieron, Julien ULg; Thoreau, François ULg

Book published by Presses Universitaires de Liège (in press)

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See detailQSAR models and the flexible regulation of chemicals
Thoreau, François ULg

Scientific conference (2017, March 14)

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See detailDu bon usage des faits en régime de " post­-vérité"
Thoreau, François ULg; Zimmer, Alexis

Article for general public (2017)

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See detailDancing without listening to the music: learning from some failures of the ‘national innovation systems’ in Latin America
Delvenne, Pierre ULg; Thoreau, François ULg

in Kuhlmann, Stefan; Ordóñez-Matamoros, Gonzalo (Eds.) Research Handbook on Innovation Governance for Emerging Economies (2017)

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See detailDrawing technical contrasts to address prenatal testing
Thoreau, François ULg

Conference (2016, December 07)

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See detailRejouer les partitions disciplinaires : l’interdisciplinarité comme épreuve dans le cas de la génomique
Fallon, Catherine ULg; Thoreau, François ULg

in Benninghoff, Martin; Crespy, Cecile; Charlier, Jean Emile (Eds.) et al Le gouvernement des disciplines académiques Acteurs, dynamiques, instruments, échelles (2016)

Les chercheurs en sciences politiques et sociales, voire les philosophes politiques, sont de plus en plus souvent « embarqués » dans des projets résolument transdisciplinaires, portés par les groupes de ... [more ▼]

Les chercheurs en sciences politiques et sociales, voire les philosophes politiques, sont de plus en plus souvent « embarqués » dans des projets résolument transdisciplinaires, portés par les groupes de recherche de différentes disciplines, engagés dans les développement scientifico-technologiques les plus pointus (que ce soit dans le secteur des nanotechnologies ou des biotechnologies médicale, voire de la gestion de la sécurité nucléaire, pour citer trois exemples récents) Le point de départ de cette proposition est l’observation du décloisonnement majeur opéré entre les disciplines de médecine et de sciences au cours des dix dernières années; y compris l'invitation des chercheurs en philosophie et en sciences politiques dans les departements de génétique humaine. Le texte analyse les enseignements de l’embarquement ab initio d’un groupe de chercheurs en science politique et philosophie dans le cadre du développement de thérapies géniques et de diagnostics prénatals. Ce projet GIGS (Gouvernementalité, génomique & santé) résulte en grande partie des réflexions d’un groupe de généticiens du centre hospitalo-universitaire qui observe avec étonnement des pratiques innovantes outre Atlantique, où l’embarquement des sciences humaines au cœur même des projets de sciences naturelles et médicales est une réalité. Si les apports potentiels de cette démarche sur le développement des sciences naturelles sont bien documentés dans la littérature STS (Van Oudheusden & Laurent 2013 ; Meyers et al 2014 ), la plupart de ces travaux traitent moins des effets de ces embarquements sur le développement de la discipline source, par exemple la science politique. Quelles sont les conditions de développement disciplinaire propre, pour les politologues et les autres chercheurs, dans un environnement aussi intégré que le GIGA où vétérinaires, médecins, ingénieurs et bientôt politologues et philosophes se côtoient, transformant les patients et leurs ADN autant que leurs propres outils disciplinaires tout en conservant un ancrage disciplinaire spécifique fort pour garantir la cohérence de leurs questionnements et l’acuité de leurs méthodes d’investigation face à un terrain partagé (Thoreau & Despret 2014). [less ▲]

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See detailWhat can a diagnosis do? The case of the "genetization" of autism
Thoreau, François ULg; Duysens, Fanny ULg

Conference (2016, November 25)

The loose condition of "autism" is undergoing through a broad process of (re)definition under the aegis of genomic medicine, which promises to find (epi)genetic causes to autism, or at least to some forms ... [more ▼]

The loose condition of "autism" is undergoing through a broad process of (re)definition under the aegis of genomic medicine, which promises to find (epi)genetic causes to autism, or at least to some forms of the Autism Spectrum Disorder. What is at stake is a scientific controversy about the very definition of the condition, i.e. the diagnosis itself. Whether it is considered primarily as a psychopathology or as a genetic disorder has consequences. It has implications regarding who would have the authority to diagnose the condition but also about the ways of taking care of persons with autism. In this paper, we depart from the paradox that some patients' organizations claim for a "geneticization" of the condition, so as to get rid of any sort of "psy-" related dimensions. It seems paradoxical because if the causes of autism are to be found in the genes, and hereby partly determined, it would seem to imply that the margins for effective therapy are narrowing down. We want to test the hypothesis that the more objective, "naturalized" a diagnosis is, the more it opens up possibilities for broadening the therapeutic reach outside the autist bodies, questioning the "milieu" of the disorder — the environment through which it is produced and the wealth of linkages and relationships through which living with autism could be eased. In other words, stressing that the diagnosis is a site to explore these contested dimensions of autism, its "geneticization" could lead to more active uptakes in patients care, whereas blurry diagnosis could not afford a similar reach. Following a pragmatic stance of an "art of consequences" (I. Stengers), we investigate the tensions raised by a genetic diagnosis which tends to "objectify" or "naturalize" the causes of the condition with respect to the lived experiences of persones with autism and their relatives, following some of the contested dimensions of a "politics of diagnosis" in their effects on affected autistic bodies and minds. To unfold those issues, our ongoing inquiry considers the interactions between various persons and institutions involved in the debate in Belgium. [less ▲]

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See detailWhat do these cattle do in a biomedical research center?
Thoreau, François ULg

Conference (2016, September)

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See detailThe politics of “grayboxing”: The use of QSAR models for the flexible regulation of chemicals
Thoreau, François ULg; Laurent, Brice

Conference (2016, May 12)

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See detailReset Inquiry!
Thoreau, François ULg; d'Hoop, Ariane; Amat, Amandine et al

in Latour, Bruno (Ed.) Reset Modernity (2016)

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See detail‘A mechanistic interpretation, if possible’: How does predictive modelling causality affect the regulation of chemicals?
Thoreau, François ULg

in Big Data & Society (2016), July-December(1), 1-11

The regulation of chemicals is undergoing drastic changes with the use of computational models to predict environmental toxicity. This particular issue has not attracted much attention, despite its major ... [more ▼]

The regulation of chemicals is undergoing drastic changes with the use of computational models to predict environmental toxicity. This particular issue has not attracted much attention, despite its major impacts on the regulation of chemicals. This raises the problem of causality at the crossroads between data and regulatory sciences, particularly in the case models known as quantitative structure–activity relationship models. This paper shows that models establish correlations and not scientific facts, and it engages anew the way regulators deal with uncertainties. It does so by exploring the tension and problems raised by the possibility of causal explanation afforded by quantitative structure–activity relationship models. It argues that the specificity of predictive modelling promotes rethinking of the regulation of chemicals. [less ▲]

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See detailVouloir vivre malgré le terrorisme
Thoreau, François ULg

Article for general public (2015)

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See detailGoverning anticipation through flexibility. The use of models for the regulation of chemicals
Thoreau, François ULg; Laurent, Brice

Conference (2015, November 18)

As the use of models is increasing within regulatory bodies, it is important to grasp both the empirical practices of producing and using them, and their political meaning. At stake here is the ... [more ▼]

As the use of models is increasing within regulatory bodies, it is important to grasp both the empirical practices of producing and using them, and their political meaning. At stake here is the possibility of identifying the characteristics of a way of governing anticipations that would be based on models. In this paper, we engage in such an exploration by focusing on models developed to predict the potential risks of chemicals. These models, called “Quantitative Structure-Activities Relationship” (QSAR), are based on statistical correlations between a set of descriptors (e.g. chemical composition, crystalline structures…) and a set of physicochemical properties, including potential toxicity. They are developed using a limited number of substances that serve as reference points, so that the properties of other chemicals could later be predicted by the model, according to their proximities to the reference points. QSAR models have been promoted by regulatory agencies for over twenty years, but have been recently gaining momentum in Europe, in the wake of the REACH regulation. As the regulation on chemicals is becoming more constraining on private companies, usual experimental approaches raise many concerns (which are lengthy, costly and often requires animal testing). Based on the analysis of the relevant documentation, interviews with scientists and regulators, as well as the ethnographic observation of a recent research project attempting to developed QSAR models for nanomaterials, this paper provides the preliminary elements for describing the mode of governing anticipation that emerges from the use of such models. We contend that QSAR approaches offer empirical examples to identify a mode of governing anticipation based on flexibility, understood at the epistemic and political levels. [less ▲]

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See detailThe pragmatics of correlation or how models reshape the government of technical objects
Thoreau, François ULg; Laurent, Brice

Conference (2015, November)

In this paper we focus on how models carry out correlations and how correlations are used as techniques of government. Correlations are fragile exercises which put together two phenomenon, e.g. one ... [more ▼]

In this paper we focus on how models carry out correlations and how correlations are used as techniques of government. Correlations are fragile exercises which put together two phenomenon, e.g. one nanoparticle and one toxic effect, without linking them with a straight causality. We examine correlations in the situated case of QSAR (quantitative structure-activity relationship) models applied to the toxicity of nanoparticles. Using scientific and regulatory documentation related to QSAR, and the preliminary results of an empirical study of a QSAR project conducted in France, we analyze the initial expectations, i.e. providing knowledge on nanoparticles useful for regulatory purposes, and how this ambition was confronted to the refusal of nanoparticles to feed the QSAR models in a satisfying way. We argue that this led to "thinking on the edge" the wonders and worries of correlation. This calls for a pragmatics of correlation: what does it do? Which are the effects and consequences of a "co-relating" approach? Exploring these questions leads us to examine the type of knowledge produced through models applied to large sets of data, and how it contributes to certain types of regulatory objectivity, particularly in the European legal context. Thus, we discuss the ways in which a pragmatics of correlation offers analytical entry points for the study of the contemporary transformation of the public administration of technical objects.   [less ▲]

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See detailLes exigences de la « terrestrialité »: une épreuve pour l’enquête
Thoreau, François ULg

Conference (2015, October 27)

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See detailPremières notes pour l'ethnographie d'un projet européen en situation embarquée
Thoreau, François ULg

Conference (2015, September 08)

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See detailComment les disciplines se reconstruisent dans des environnements hybrides et dynamiques
Fallon, Catherine ULg; Thoreau, François ULg

Scientific conference (2015, February 06)

Les chercheurs en sciences politiques et sociales, voire les philosophes politiques, sont de plus en plus souvent « embarqués » dans des projets résolument transdisciplinaires, portés par les groupes de ... [more ▼]

Les chercheurs en sciences politiques et sociales, voire les philosophes politiques, sont de plus en plus souvent « embarqués » dans des projets résolument transdisciplinaires, portés par les groupes de recherche de différentes disciplines, engagés dans les développement scientifico-technologiques les plus pointus, que ce soit dans le secteur des nanotechnologies ou des biotechnologies médicales (pour citer deux exemples récents,Thoreau 2013) . Cet article prend comme point de départ un projet pluriannuel qui a obtenu des subsides pour plonger pendant une longue période trois chercheurs (philosophe, anthropologue, politologue) dans un centre de recherche en génomique humaine appliquée, installé dans une aile du Centre-Hospitalo-Universitaire. En tant que coordinateurs de ce projet, nous voulons aborder ab initio (1) la question des conditions d’exercice de notre démarche de terrain et (2) les conditions de notre service en tant que politologues au fil de cette trajectoire. [less ▲]

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See detailUn problème de constitution – faire exister des catégories réglementaires pour les objets techniques
Laurent, Brice; Thoreau, François ULg

Conference (2014, December 05)

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