References of "Thomé, Jean-Pierre"
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See detailExposure to an organochlorine pesticide (chlordecone) and development of 18-month-old infants
Boucher, O; Simard, M.-N.; Muckle, G et al

in NeuroToxicology (2013), 35(1), 162-168

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See detailEffects of tributyltin (TBT) and triphenyltin (TPT) on the reproduction of the freshwater snail Lymnaea stagnalis
Lagadic, Laurent; Giusti, Arnaud ULg; Barsi, Alpar et al

Conference (2012, December 10)

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See detailStare-Capmed : Présentation générale du projet et exemple d'une action : "Impact de l'ancrage sur la dynamique des herbiers de posidonies".
Michel, Loïc ULg; Champenois, Willy ULg; Borges, Alberto ULg et al

Conference (2012, May 16)

STARE-CAPMED (STAtion of Reference and rEsearch on Change of local and global Anthropogenic Pressures on Mediterranean Ecosystems Drifts) est un projet de recherche mis en place par Stareso S.A.S. depuis ... [more ▼]

STARE-CAPMED (STAtion of Reference and rEsearch on Change of local and global Anthropogenic Pressures on Mediterranean Ecosystems Drifts) est un projet de recherche mis en place par Stareso S.A.S. depuis janvier 2012. Il a pour objectif d’établir un site de référence à long terme pour la compréhension, par la recherche fondamentale, des processus de l’évolution des écosystèmes méditerranéens côtiers et océaniques en réponse aux changements actuels globaux et locaux des pressions anthropiques. Centré sur la Baie de Calvi et le proche large, il vise à fournir un référentiel basé sur des mesures à haute fréquence qui doivent pouvoir complémenter les réseaux de surveillance basse fréquence et de recherches existants et ainsi faire progresser la compréhension des processus. En outre, le projet doit fournir aux utilisateurs finaux (collectivités locales et régionales, administrations nationales, ...) des orientations de gestion basées sur l’analyse étayée des processus en jeux. Financé par l’Agence de l’eau RMC et la Collectivité Territoriale de Corse, le projet, multidisciplinaire, se décline actuellement selon 10 axes de travail : • Suivi du cadre hydrographique et physico-chimique • Suivi et quantification des pressions anthropiques • Ecosystème planctonique • Benthos de substrat meuble • Benthos de substrat dur et faune vagile • Phanérogames marines et écosystèmes associés • Mouillages et processus d’altération des herbiers de posidonies • Ecotoxicologie et polluants émergents • Bilan CO2 et métabolisme des écosystèmes • Zones protégées, espèces nouvelles, recrutement Pour chacun de ces axes, la stratégie d’échantillonnage est basée sur la comparaison de données obtenues durant des périodes où l’impact anthropique est faible (octobre-avril) avec celles obtenues durant des périodes de pression intense (mai-septembre), et sur la comparaison de données issues de sites de référence peu impactés avec celles provenant de sites où l’impact anthropique est reconnu. A titre d’exemple, le but de l’action "Mouillages et processus d’altération des herbiers de posidonies" est de mettre en évidence les conséquences des altérations liées à l’arrachage de faisceaux de posidonies sur la vitalité de l’herbier. Des zones où la pression de mouillage est reconnue seront définies sur base des travaux de cartographie de l’herbier, également réalisés dans le cadre du projet STARE-CAPMED. Elles seront comparées avec des zones d’herbiers sains témoins par la caractérisation du sédiment (mesures de compacité in situ, mesures des concentrations en O2 et nutriments et du pH de l’eau interstitielle, granulométrie et teneur en matière organique du sédiment, proportions de rhizomes et morts) ainsi que par la définition de l’état physiologique des faisceaux de posidonies (mesures biométriques classiques, analyses des contenus élémentaires en carbone, azote et phosphore) et par l’application d’indices écologiques définis par la DCE (PREI, BIPO, …). Les résultats obtenus permettront d’avoir une vue d’ensemble des processus par lesquels l’impact physique des mouillages de bateaux de plaisance occasionne des dégâts aux herbiers de posidonies. Ils pourront ainsi fournir une base de connaissances solide aux gestionnaires soucieux de limiter cet impact. [less ▲]

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See detailFrom field to laboratory studies: case of selenium in Chelonians
Dyc, Christelle ULg; Thomé, Jean-Pierre ULg; Das, Krishna ULg

in Proceedings of the 32nd Annual Symposium on Sea Turtle Biology and Conservation (2012, March)

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See detailCombined effects of deltamethrin, temperature and salinity on oxidative stress biomarkers and acetylcholinesterase activity in the black tiger shrimp (Penaeus monodon)
Tu, H.T.; Silvestre, F; Meulder, B.D. et al

in Chemosphere (2012), 86(1), 83-91

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See detailAccumulation of Polychlorinated biphenyls in adipocytes: Selective targeting to lipid droplets and role of caveolin-1
Bourez, S; Le Lay, S; Van den Daelen, C et al

in PLoS ONE (2012), 7(2), 31834

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See detailDifferential changes of fat-soluble vitamins and pollutants during lactation in northern elephant seal mother-pup pairs
Debier, C; Crocker, D.E.; Houser, D.S. et al

in Comparative Biochemistry & Physiology Part A : Molecular & Integrative Physiology (2012), 162(4), 323-330

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See detailPrecision-cut liver slices to investigate responsiveness of deep-sea fish to contaminants at high pressure
Lemaire, B; Debier, C; Buc Calderon, P et al

in Environmental Science & Technology (2012), 46(18), 10310-10316

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See detailScaphandre La science rencontre l'art: L'art
Haubruge, Eric ULg; Bay, Daniel ULg; Semal, Jean et al

in Haubruge, Eric; Bay, Daniel; Semal, Jean (Eds.) Scaphandre La science rencontre l'art (2012)

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See detailFlux-based Risk Assessement of the impact of Contaminants on Water resources and ECOsystems
Jamin, Pierre ULg; Dujardin, Juliette; Crèvecoeur, Sophie et al

Report (2012)

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See detailFlux-based risk assessment of the impact of contamnants on water ressources and ecosystems - FRAC-WECO.
Jamin, Pierre ULg; Dujardin, J.; Crévecoeur, Sophie et al

Report (2012)

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See detailUsing sets of behavioral biomarkers to assess short-term effects of pesticide: a study case with endosulfan on frog tadpoles
Denoël, Mathieu ULg; D'hooghe, Bastien; Ficetola, G. Francesco et al

in Ecotoxicology (2012), 21(4), 1240-1250

Pesticides and other chemicals often have detrimental effects at environmental concentrations. Many amphibian species are particularly threatened because of their susceptibility but also because wetlands ... [more ▼]

Pesticides and other chemicals often have detrimental effects at environmental concentrations. Many amphibian species are particularly threatened because of their susceptibility but also because wetlands are often polluted. Behavioral assessments of toxicity have the advantage of showing sublethal effects but quantitative measures at varied scales of integrations are rarely considered together. In this study, we aimed at showing that these behavioral endpoints could be differently affected across time and concentrations, and be biomarkers of toxicity. To this end, we tested the effects of an organochlorine pesticide (endosulfan) on amphibians during a standard 96 h test. We evaluated possible lag effects in continuing the analyses after removal of the pesticide. The study was based on 240 tadpoles (4 pesticide treatments: 0.4, 3, 22, and 282 lg/l, 1 control and 1 solvent-control). Abnormal behaviors such as lying and swirling rapidly were exhibited only in the presence of the pesticide. Essential functions such as breathing and feeding were deeply affected by the pesticide: contaminated tadpoles breathed and fed less than control tadpoles. They also moved less and occupied a more central position in the aquariums in the presence of the pesticide. A higher mortality was only found at the highest concentration. These results suggest that endosulfan is toxic to amphibians at environmental concentrations. Behavioral markers showed potential as early warning systems. They should thus be used in complement to other markers to detect sublethal effects only a few days after application of the pesticide and at concentrations where mortality does not occur. [less ▲]

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See detailReproductive impact and proteomic analysis of androgenic and anti-androgenic disruptors on the hermaphroditic freshwater gastropod Lymnaea stagnalis
Giusti, Arnaud ULg; Ducrot, Virginie; Joaquim-Justo, Célia ULg et al

Poster (2011, November)

In this study, e ects of two androgens (tributyltin and testosterone), one antiandrogen (cyproterone acetate) and one estrogen (chlordecone) on growth and reproduction were investigated in the ... [more ▼]

In this study, e ects of two androgens (tributyltin and testosterone), one antiandrogen (cyproterone acetate) and one estrogen (chlordecone) on growth and reproduction were investigated in the hermaphrodite gastropod Lymnaea stagnalis. In this study, exposure to a range of concentrations (ng/l to μg/l) of each chemical was performed during 21 days. e number of clutches and the number of eggs per clutch were monitored. A decrease in clutches laid per snail was observed after exposure to tributyltin (540, 1180 and 2600 ng/l) and chlordecone (10, 22, 50 and 110 μg/l). A signi cant decrease in egg laid per snail was observed after exposure to tributyltin (540, 1180 and 2600 ng/l) and chlordecone (50 and 110 μg/l). An increase of egg abnormalities ratio in exposed snails (atrophied albumen, polyembryonicity,...) was observed in L. stagnalis following exposure to testosterone (2, 22, 50 and 110 ng/l), cyproterone acetate (4,5 and 50 μg/l), tributyltin (110 and 244 ng/l) and chlordecone (4,5 and 10 μg/l). Investigation of alteration in protein expression in exposed snails was performed using proteomic analysis such as 2D-DIGE. Mass spectrometry identi cation was performed on proteins with altered expression. We could establish correlation between reproductive endpoints and changes in proteins involved in egg formation and in egg laying were underlined. Egg yolk ferritin, the main protein of egg yolk, was shown to be reduced signi cantly in relationship with a decrease of egg yolk quality after exposure to tributyltin 540 ng/l and cyproterone acetate 4,5 μg/l. Ovipostatin, a protein proved to reduce egg masses, was signi cantly over expressed in snails exposed to 50 μg/l of chlordecone and were in relationship with a reduction of clutches laid by individuals. Further western blot analysis on those proteins involved in the reproduction are underway. ese analysis will enable us to con rm and re ne with more speci city the 2D-DIGE results for the selected proteins. e results of this study can help to establish new biomarkers of exposure of endocrine disruptors in freshwater environment and can provide new insight on mode of action of endocrine disruptors in L. stagnalis. [less ▲]

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See detailGroundwater quality assessment of one former industrial site in Belgium using a TRIAD-like approach.
Crévecoeur, Sophie; Debacker, Virginie ULg; Joaquim-Justo, Célia ULg et al

in Environmental Pollution (2011), 159(10), 2461-2466

Contaminated industrial sites are important sources of pollution and may result in ecotoxicological effects on terrestrial, aquatic and groundwater ecosystems. An effect-based approach to evaluate and ... [more ▼]

Contaminated industrial sites are important sources of pollution and may result in ecotoxicological effects on terrestrial, aquatic and groundwater ecosystems. An effect-based approach to evaluate and assess pollution-induced degradation due to contaminated groundwater was carried out in this study. The new concept, referred to as “Groundwater Quality TRIAD-like” (GwQT) approach, is adapted from classical TRIAD approaches. GwQT is based on measurements of chemical concentrations, laboratory toxicity tests and physico-chemical analyses. These components are combined in the GwQT using qualitative and quantitative (using zero to one subindices)integration approaches. The TRIAD approach is applied for the first time on groundwater from one former industrial site located in Belgium. This approach will allow the classification of sites into categories according to the degree of contaminant-induced degradation. This new concept is a starting point for groundwater characterization and is open for improvement and adjustment. [less ▲]

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See detailThyroid hormone disrupting chemicals in sea bass (Dicentrarchus labrax) from European coasts
Schnitzler, Joseph ULg; Michel, Loïc ULg; Klaren, Peter et al

Conference (2011, February 25)

Polychlorinated biphenyls (PCBs) and organochlorine pesticides like Dichloro-Diphenyl-Trichloroethane (DDTs), Hexachlorocyclohexanes (HCHs), aldrin, dieldrin and trace elements (Cd, Cu, Se, Pb, Zn and Hg ... [more ▼]

Polychlorinated biphenyls (PCBs) and organochlorine pesticides like Dichloro-Diphenyl-Trichloroethane (DDTs), Hexachlorocyclohexanes (HCHs), aldrin, dieldrin and trace elements (Cd, Cu, Se, Pb, Zn and Hg) were analysed in the muscle of sea bass (Dicentrarchus labrax) sampled in coastal regions near several important European river mouths (Gironde, Charente, Loire, Seine and Scheldt). These potential endocrine disrupting chemicals were present in European coastal waters. Even if their concentrations were well below the Maximum Residue Limits set by the governments, they induced alterations of the endocrine system. We established correlations between contaminant concentrations and effects on the thyroid system in sea bass. The contaminants induced modifications of the metabolic pathways of thyroid hormones and enhanced thyroid hormone synthesis. The activity of T4 Outer Ring Deiodinase was increased, that leads to an intensified conversion of thyroxine (T4) to its more biologically active form triiodothyronine (T3). Meanwhile, the activity of T4 sulfatation was reduced, that leads to a lowered biliary excretion of thyroid hormones. The modified metabolic pathways of the thyroid hormones can be interpreted as a tool to homeostatically maintain the thyroid hormone status. Of all tested compounds, the higher chlorinated PCBs seemed to be the most implicated in this perturbation. The nature of thyroid hormone synthesis, signalling and regulation is highly conserved among vertebrates. Although we cannot extrapolate thyroid toxicity data directly from one species to another, these environmental factors may well affect thyroid function in other species, including humans. [less ▲]

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See detailPrecision-Cut Liver Slices of Salmo salar as a tool to investigate the oxidative impact of CYP1A-mediated PCB 126 and 3-methylcholanthrene metabolism
Lemaire, B; Beck, M; Jaspart, M et al

in Toxicology in Vitro (2011), 25(1), 335-342

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See detailErratum to "Do sewage treatment plant discharges substantially impair fish reproduction in polluted rivers?" [Sci. Total Environ. 372 (2007) 497-514]
Douxfils, J; Mandiki, R; Silvestre, F et al

in Science of the Total Environment (2011), 409(19), 4139

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See detailToothed whales in the northwestern Mediterranean: Insight into their feeding ecology using chemical tracers
Praca, Emilie; Laran, Sophie; Lepoint, Gilles ULg et al

in Marine Pollution Bulletin (2011), 62(5), 1058-1065

Risso’s dolphins, pilot whales and sperm whales rarely strand in the northwestern Mediterranean. Thus, their feeding ecology, through the analysis of stomach contents, is poorly known. The aim of this ... [more ▼]

Risso’s dolphins, pilot whales and sperm whales rarely strand in the northwestern Mediterranean. Thus, their feeding ecology, through the analysis of stomach contents, is poorly known. The aim of this study was to gain further insight into the segregation/superposition of the diet and habitat of Risso’s dolphins, pilot whales and sperm whales using chemical tracers, namely, stable isotopes (d13C, d15N) and orga- nochlorines. Significantly different d15N values were obtained in Risso’s dolphins (11.7 ± 0.7‰), sperm whales (10.8 ± 0.3‰) and pilot whales (9.8 ± 0.3‰), revealing different trophic levels. These differences are presumably due to various proportions of Histioteuthidae cephalopods in each toothed whale’s diet. Similar d13C contents between species indicated long-term habitat superposition or corroborated impor- tant seasonal migrations. Lower congener 180 concentrations (8.20 vs. 21.73 lg.g􏰀1 lw) and higher tDDT/ tPCB ratios (0.93 vs. 0.42) were observed in sperm whales compared with Risso’s dolphins and may indi- cate wider migrations for the former. Therefore, competition between these species seems to depend on different trophic levels and migration patterns. [less ▲]

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